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HS Code |
378555 |
| name | Cis-Himic Anhydride |
| molecular_formula | C7H8O3 |
| molecular_weight | 140.14 g/mol |
| CAS_number | 129-64-6 |
| appearance | White to off-white crystalline solid |
| melting_point | 196-198°C |
| solubility_in_water | Slightly soluble |
| density | 1.39 g/cm³ |
| smiles | O=C1OC(=O)C2CCC1C2 |
| synonyms | Cis-1,2,3,6-Tetrahydrophthalic anhydride |
| storage_conditions | Store in a cool, dry, well-ventilated area |
As an accredited Cis-Himic Anhydride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Cis-Himic Anhydride is packaged in a 100g amber glass bottle, sealed and labeled with hazard symbols, product name, and batch number. |
| Shipping | Cis-Himic Anhydride should be shipped in tightly sealed containers under cool, dry conditions, away from sources of moisture and incompatible materials. Ensure packaging complies with local and international regulations for hazardous chemicals. Proper labeling and documentation are required. Use appropriate cushioning to prevent breakage during transit and handle with care. |
| Storage | Cis-Himic Anhydride should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from moisture, heat, and incompatible substances such as strong bases, acids, and oxidizing agents. Ensure the chemical is protected from light and atmospheric humidity. Properly label the storage container, and follow all standard chemical safety and handling procedures. |
Applications of Cis-Himic Anhydride in Industrial ManufacturingCis-Himic Anhydride serves as a specialized intermediate in select chemical processes, contributing to performance and compliance in downstream production. As a dedicated manufacturer, we ensure grades and documentation support for direct industrial integration. 1. Polyimide Resin Synthesis for ElectronicsCis-Himic Anhydride enables production of high-performance polyimide resins used in flexible printed circuits and insulating films. Manufacturers utilize precise imide-forming reactions, maintaining defined molar ratios for superior heat stability and electrical insulation. Production requires strict adherence to moisture control and impurity profiles to meet electronics-industry expectations. Industry compliance standards
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2. Curing Agent for Automotive Polyurethane CoatingsThe compound functions as a specialty cyclic anhydride curing agent, enhancing hardness and chemical resistance in automotive topcoats. Formulators control addition rates based on crosslink density targets, while downstream users validate through accelerated weathering and solvent rub testing. Careful staging and heat profiles prevent yellowing or incomplete cure. Industry compliance standards
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3. Modifier in Fragrance Ingredient ManufacturingThis intermediate supports synthesis of macrocyclic musk compounds, imparting structural characteristics valued in fine fragrance and air care formulations. Chemical engineers rely on precise catalyst systems and temperature profiles for selective ring closure, minimizing byproducts such as unsaturated ketones to meet IFRA-defined purity requirements. Downstream processes include distillation and controlled hydrogenation. Industry compliance standards
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4. Precursor for Agrochemical Active Ingredient SynthesisCis-Himic Anhydride acts as a starter cycle for select herbicide and plant growth regulator APIs, especially in synthesis of pyridine or cyclopentanecarboxylic derivatives. Fine chemical plants tightly control feedstock purity and trace metal content before employing multi-stage hydrogenation and acylation protocols. Manufacturers calibrate usage to optimize crop-specific action spectrum and regulatory residue thresholds. Industry compliance standards
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Working in chemical manufacturing creates a unique rhythm. You get to see the lifecycle of a product from raw extraction to refined utility. Cis-Himic Anhydride, also recognized across some industries as cis-1,2,3,6-Tetrahydrophthalic anhydride, stands out for people who value consistency at the molecular level. When we measure each batch, the familiar tang of its distinct odor is one of the automatic signals our team uses to confirm the right outcome. In the production hall, the crystalline solid forms so neatly — it gives us confidence that the process lines up with careful filtration and distillation, as it should.
This compound, with its evocative aroma, has served perfumers and resin developers for decades. It’s more than a niche ingredient; it’s a ticket to reliable esterification in specialty scent chemistry or as a key building block for a variety of unsaturated polyester resins. We pay close attention to stereochemistry here. The cis-isomer’s structural quirks mean better reactivity in select reactions and less hassle with re-purification downstream.
The model we produce maintains a consistent specification — purity well above 99% by gas chromatography, low moisture, and tightly controlled melting range. We set our standards after learning over years what keeps customers from headaches. An uncontrolled melting point, a few tenths off where you want it, ruins a melt-blend process. Too much color and a formulator’s resin or fragrance profile veers into unwanted territory. Our steady process control catches these issues early on.
What separates our Cis-Himic Anhydride most clearly in daily work is its behavior in applications. The crystalline shape and low impurity content make solid-handling smoother for compounding. In resins production, batch consistency does not happen by accident. Screening for trace by-products in the anhydride step saves hours — and money — in downstream purifications.
Customers in the dyes, adhesives, or UV-curable formulations sectors come to us because their outcomes are tied to these specifications. Tiny loads of water or byproduct acids destabilize catalyst packages or shorten shelf life in demanding materials like CVD precursors or specialty polyesters.
Cis-Himic Anhydride is an isomer. The difference from its trans sibling or from generic phthalic anhydrides turns into real impact during synthesis. Chemists who work with both forms will vouch that the cis product opens up routes for making fine fragrance intermediates, reactive prepolymers, and even UV-curing agents that the trans simply cannot cover at the same performance level. Its melting point, odor character, and energy input change the rules in your reactor.
We get regular questions about switching between isomers if one or the other spikes in price. The short answer, learned the hard way, is that results rarely match up, and unexpected gels or color drifts are common if the molecular geometry changes mid-stream. Trying to stretch out a trans or mixed material in an application meant for cis usually brings more cost in lost productivity or surprise rework.
Our time in manufacturing turns up a handful of practical realities, especially for those running batch reactors, extruders, or fine fragrance compounding. Raw material stability shapes every day. Imagine watching over a vessel as it warms and realizing that impurity levels, moisture, or the wrong isomer keep fouling the batch valves, slowing up a week’s order. Every shift, we hear from operators who have adjusted maintenance schedules just to compensate for these issues before they choose our material. Once end-users switch to tighter-controlled Cis-Himic Anhydride, those line slowdowns become a memory.
Another hard-earned lesson involves handling. Cost sometimes opens doors to lower-purity or recycled material, but those choices cost twice in time and risk for most downstream uses. Since residual acids form sticky layers or unpredictable color, we keep our crystalline product tightly sealed from moisture the moment it leaves the reactor.
Users who melt, blend, or dissolve the anhydride directly into resins or intermediates tell us the fine particle consistency and high transparency of our crystals save on filtration, and let quality control move batches with fewer retests.
The real impact of chemical building blocks like Cis-Himic Anhydride lies in their ability to disappear into a process and let the operator focus on other pain points. The fewer process corrections an ingredient requires, the less downtime and scrap show up by period-end. We learned after a few rough years that making one less variable for our customers can save full shifts of labor over time.
For resin and coating clients, the advantages surface clearest. The cis isomer slots into unsaturated polyester synthesis where reactivity values, color needs, and flow requirements hold tight tolerances. Its structure supports quicker curing, steadier viscosity targets during blending, and a more predictable end-use profile for the final polymer.
Aroma chemists, especially those developing green or citrus bases, chase the unique profile of cis-Himic Anhydride. The compound builds middle and top notes for naturalistic fragrance designs. Any hint of the trans or generic isomers results in a muddiness that turns up on consumer testing strips, killing batch after batch. For these users, trace impurities — hard to spot without good analytics — ruin the work put into a custom formulation. We’ve heard the frustration from customers who chose a lower-grade source, only to see their flagship blend end up inconsistent on the retail shelf.
Cis-Himic Anhydride delivers steady value where selectivity boosts process yield or where product appearance needs to stay inside tight color windows. In unsaturated polyesters, for example, technicians see a reduction in side reactions because the cis orientation reduces unsaturated byproducts and oxidative color formation.
Adhesive formulators leverage the anhydride functionality for curing mechanisms in hot-melt and pressure-sensitive adhesives. They report that our material’s low free acid reduces corrosion in dispensing equipment and supports stronger shelf stability across seasonal temperature swings.
Colorant and pigment manufacturers appreciate the compound for its ability to help form clear, high-gloss finishes. Its crystalline structure disperses easily without settling, letting blenders run smoother lines and reduce scrap rates.
Producing Cis-Himic Anhydride involves its own share of headaches — not just synthesis, but also the practical matter of keeping it pure through drying, packaging, and storage. Our operation had to redesign the air filtration in the packaging area once seasonal humidity changes started caking the anhydride before shipping. Operators noticed a drift in melt-point values, directly traced back to traces of atmospheric moisture.
We shifted to nitrogen atmosphere handling and invested in new desiccant drying towers. The cost was noticeable, but the fewer customer complaints about off-spec batches paid off in repeat orders and credibility. For packagers, the small step of resealing bags immediately after sampling now matters far more than the cost of packaging film.
New entrants in chemical synthesis sometimes overlook these details. Chemical stability — not just at shipment, but on the dock, through the warehouse, and inside a day-to-day process — decides whether the final formulation performs at or above spec. All it takes is a few wet drums to teach anyone that material science and logistics go together.
Handling requirements in the warehouse grew as our customer base expanded into regions with higher temperature and moisture swings. We aligned our packaging standards accordingly, switching out undesirable fiber drums for lined, sealed options. Some of our resin manufacturing customers saw less dust-off and fewer clogged lines after the switch, doubling batch throughput. We treat each complaint and each improvement as another source of practical feedback.
Himic Anhydride appears in several forms, and users sometimes mix up the names. Standard Himic usually means a blend, sometimes dominated by the trans isomer. Phthalic anhydride, on the other hand, sports a very different backbone and melting behavior. The cis form has been a go-to for chemists who need selectivity — not just a commodity acid anhydride, but a compound with a specific, reliable function.
The reactivity of Cis-Himic Anhydride runs higher in reactions that depend on the cis geometry. For example, certain esterifications build from this isomer with higher conversions, yielding more predictable results during scale-up to pilot and commercial production. The functional performance becomes apparent during application — shorter cure times in unsaturated resins, more stable polymer backbones, and distinct contributions to aroma compounds.
Pricing swings can tempt a formulator to substitute generic or trans-heavy grades, but process experience has shown that off-quality material introduces more blend variability and, in high-value end-use manufacturing, increases the double-handling needed to catch color, purity, or yield excursions. This wastes not just raw feedstock, but also labor and reputation. Making this mistake on a rush order reveals how irreplaceable tight material choice really is.
Down in the lab, newer applications keep showing up on R&D benches. Some teams focus on modified resins offering greener, more durable packaging materials. Here, the cis isomer’s triple set of carbonyls and its reactivity pattern give polymer chemists tighter control of substitution positions, translating into improved thermomechanical properties or biodegradability targets.
There’s growing interest from materials scientists. A few university collaborators ran pilot runs with us to test the anhydride’s value in next-generation UV-cure composites. The results pointed to better cure rates, cleaner surfaces, and a drop in out-gassing. Less post-cure work translates into real cost savings.
Some electronics industry partners now look at Cis-Himic Anhydride as a reactive diluent for adhesives and encapsulants. Because the anhydride groups are reactive, formulators can fine-tune crosslink density and cut down on unwanted plasticizer migration. In test lines, cured components showed less warping after thermal cycling.
Battery and photovoltaic researchers raise the bar for purity every year. Here, too, the cis form’s clean handling matters more than ever, since even trace impurities measurably shift cell performance or contribute to fade. We get specification requests that demand near-total absence of metals or organics. This drives us to re-examine and re-invest in purification, filtration, and process analytics.
Cis-Himic Anhydride manufacturing is not immune to pressure points. Feedstock sourcing ties up time and capital since the raw material pool swings seasonally right along with upstream plant output. Logistics, especially global, adds headaches; during port slowdowns, critical customers request expedited production that compresses normal QA cycles.
Another area operators focus on is sustainability. Process waste and energy consumption are tightly monitored now. We saw a change once larger customers began publishing environmental metrics. Our own team invested in thermal energy recovery setups and redesigned process chillers to support a reduced carbon footprint. Some customers have even asked to audit solvent recovery lines as part of their supplier evaluations — another indicator that transparency around manufacturing methods pays off.
Yet at every production step, we find the most value in ongoing dialogue with end-users. The further we engage, the more insight we gain into how small purity or consistency tweaks pass through the entire value chain. Whether the feedback comes from a pilot plant, a coatings lab, or a perfume house, the result shapes the way we adjust synthesis and QA.
Price pressure in chemical supply chains never disappears. End-users often look for savings by swapping out high-purity materials for less refined options, especially in markets where short-term cost wins approvals. We learned from experience that more process issues spring from inconsistent anhydride supply than from nearly any other input. Once a cheaper material lands on the shop floor, performance drops are not always immediate — they pop up days or weeks later with quality deviations, slower runs, and customer complaints.
Factory runs rely on consistency. Experienced plant managers buy tight-range materials to keep scrap low and machine wear to a minimum. Managers often share stories about switching back to a steadier grade of Cis-Himic Anhydride after unsuccessfully trialing recycled or alternate suppliers. In large resin kettles, even minor impurity drifts balloon into lost yield, extra filtration, or expensive extended runs.
Real performance gains emerge not just on paper but at the interface of production and application. Consistent anhydride content, low water, and a predictable melt-point all mean fewer operator interventions. Each shift saved is a real-world win that multiplies at full manufacturing scale. For users running multi-ton operations, one or two percent higher conversion or a day’s shorter downtime moves the bottom line.
The focus for us as a manufacturer remains on strict sourcing, careful process control, and real-time batch analytics — not just at annual audits but every day, every shipment. Chemical production rarely gets easier, but the right foundation delivers dependability through whatever market swings or specification changes arise.
Cis-Himic Anhydride holds its stature among essential intermediates because of this reliability and performance — especially for resin, coating, and aroma compound producers. As more industries focus on lifecycle impact and traceability, our process innovations lean toward sustainable energy, documentation, and tighter tolerances.
Every improvement in throughput, batch-to-batch repeatability, or waste reduction comes as the direct result of feedback from those running the reactors and compounding machines. The working reality at a chemical manufacturing plant focuses less on what a product could do, and more on what it consistently delivers — both for internal QA teams and for every plant manager downstream. That accountability, paired with the lessons learned on the production floor, keeps Cis-Himic Anhydride’s value clear amidst constant shifts in demand, application techniques, and end-user requirements.