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Carbamic Acid

    • Product Name Carbamic Acid
    • Alias Aminic acid
    • Einecs 205-087-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    417190

    Chemical Name Carbamic acid
    Formula CH3NO2
    Molar Mass 61.04 g/mol
    Appearance Colorless solid (unstable in pure form)
    Melting Point Decomposes before melting
    Boiling Point Decomposes before boiling
    Iupac Name Aminoformic acid
    Cas Number 463-77-4
    Solubility In Water Soluble
    Pka 3.46
    Structure H2NCOOH
    Stability Unstable, decomposes to ammonia and carbon dioxide
    Odor Ammonia-like
    Uses Intermediate in urea and carbamate chemistry

    As an accredited Carbamic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Carbamic Acid, 100 grams, is packed in a sealed amber glass bottle with a tamper-evident cap and clear hazard labeling.
    Shipping Carbamic acid should be shipped in tightly sealed, corrosion-resistant containers, protected from moisture, heat, and incompatible substances. Transport should comply with relevant hazardous material regulations, ensuring proper labeling and documentation. Due to its instability, rapid delivery under controlled conditions and handling by trained personnel are essential for safety and material integrity.
    Storage Carbamic acid should be stored in a cool, dry, and well-ventilated area, away from sources of moisture and incompatible substances such as strong bases and oxidizers. It should be kept in tightly sealed, corrosion-resistant containers to prevent decomposition, as carbamic acid is unstable and can hydrolyze easily. Ensure labeling and handling procedures comply with safety regulations to minimize exposure risks.
    Application of Carbamic Acid

    Applications of Carbamic Acid in Industrial Manufacturing

    Carbamic Acid serves as a niche yet critical intermediate in multiple industrial channels, supporting the synthesis and modification of higher-value chemical products. Its unique reactivity and controlled decomposition profile enable precise transformations demanded by specialty segments. Below, we detail established application areas, focusing on downstream use cases that adhere to established compliance frameworks, process requirements, concentration guidance, and finished good profiles.

    1. Custom Synthesis of Pharmaceutical Intermediates

    Specialty pharma manufacturers use this raw material for the in-situ generation of carbamates and N-substituted urea derivatives, which are key building blocks in analgesic, anti-inflammatory, and antiviral APIs. Carbamic Acid’s transient nature requires tight process control, typically managed within closed systems under regulated cGMP protocols. It participates as an activated group donor in amination, alkylation, and acylation steps at defined synthesis stages preceding intermediate purification and final API conversion.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • 21 CFR Part 210/211 (FDA cGMP requirements)
    • EU GMP EudraLex Volume 4
    • Pharmacopoeia Monographs (USP-NF, EP, JP as per API destination)

    Typical usage ratio

    • 0.8–1.5 molar equivalents, oversupplied when necessary to drive complete conversion; engineering controls set the exact charge relative to downstream amine or alcohol nucleophile excess.

    Downstream process integration

    • Introduced after solvent swap or pre-activation with base, immediately preceding carbamoylation or alkylation stages; decomposes on heating or acidification to trigger intermediate formation.

    Final product types

    • N-monosubstituted urea, carbamate-protected pharmaceutical intermediates, direct precursors to therapeutic APIs (e.g., anti-HIV, anti-hypertensive agents).

    2. Organic Synthesis in Agrochemical Active Ingredients

    The crop protection industry employs Carbamic Acid as a masked isocyanate or carbamoyl transfer source, especially critical in the one-pot formation of pesticide and herbicide intermediates. It supports high-purity carbamate esterification, directly impacting the downstream safety and efficacy of agrochemical finished goods. The reagent's controlled introduction within closed reaction loops prevents exposure and promotes conversion specificity.

    Industry compliance standards

    • FAO/WHO Technical Guidelines for Pesticide Synthesis and QC
    • ISO 9001:2015 for Chemical Manufacturing
    • REACH (EC No 1907/2006)
    • Applicable OECD Guidelines for Testing of Chemicals

    Typical usage ratio

    • 1.1–1.3 equivalents relative to target alcohol or amine functional group, adjusted for impurity levels and stage yield optimization during batch synthesis.

    Downstream process integration

    • Metered into reaction during carbamoylation steps following in situ base treatment, used in flow chemistry or traditional stirred reactors prior to crystallization or extraction workup.

    Final product types

    • Carbamate-based pesticides (e.g., carbaryl, methomyl), herbicide intermediates, insecticide actives for encapsulation in seed treatment formulations.

    3. Polymer Modification and Specialty Resin Manufacturing

    Within the performance materials segment, manufacturers introduce Carbamic Acid to modify polyol and polyamine systems. Its purpose is to generate carbamate functionalities that enhance flexibility, reactivity, or crosslinking in specialty urethane and epoxy resins. Precise timed addition controls molecular weight, gel time, and decomposition profile, which are vital for setting final product characteristics and application compliance.

    Industry compliance standards

    • ISO 9001:2015 for Quality Management
    • ASTM D2578 (Polymer and Resin Testing)
    • RoHS and SVHC screening for end-use electronics compatibility
    • UL 94 (flammability assessment for plastics in electrical applications)

    Typical usage ratio

    • Up to 2.5% by weight based on total polyol content for reactive resin formulations; actual input proportional to desired crosslink density and end-use performance criteria.

    Downstream process integration

    • Added to prepolymer mixing tanks under inert atmosphere after temperature stabilization; reacts prior to or concurrent with chain extension/crosslinker stages within batch or continuous production lines.

    Final product types

    • Specialty polyurethane foams, flexible and rigid resin systems, high-performance adhesive backings, and engineered plastics for electronics or automotive sectors.

    4. Fine Chemical Synthesis for Textile Dye Precursors

    Specialty dye and pigment producers depend on controlled use of Carbamic Acid in the preparation of reactive dye intermediates, especially where carbamate-protected moieties are favored for lightfastness and wash resistance. It functions as a transient identifier, whether in small-molecule colorant synthesis or during stepwise coupling of aromatic scaffolds. Process engineers monitor charge timing and acidity to preserve color yield and downstream dyeing consistency.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (for hazardous substance exclusion in dyes)
    • ISO 14001 (environmental management during dye synthesis)
    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • REACH Annex XVII restrictions for textile chemicals

    Typical usage ratio

    • 0.9–1.2 molar equivalents per reactive site, with in-process analytical controls to prevent excess carbamate residuals in final dyes.

    Downstream process integration

    • Administered during protection reactions ahead of azo coupling, or directly in last-step modifications for improved substrate binding and post-treatment stability.

    Final product types

    • Reactive dye precursors for cotton and cellulose blends, intermediate color bases for high-performance dispersion dyes, and post-treat finished dyestuffs used in apparel, technical textiles, and digital printing inks.

    Free Quote

    Competitive Carbamic Acid prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Carbamic Acid: Precision Chemistry from the Manufacturer’s Bench

    A Direct Look at Carbamic Acid from Our Production Floor

    Every batch that leaves our plant carries not just a chemical name, but a reputation built from more than two decades of precision and disciplined work. Carbamic acid, known to chemists as H2NCOOH, finds a role in countless synthesis pathways and downstream formulations. This material’s profile stands apart in day-to-day applications, and our team understands the real substance beneath its formula, well beyond the abstractions you might see in a catalog. The way we process and package this acid underscores a commitment to purity, consistency, and performance that comes from firsthand experience.

    Understanding Carbamic Acid’s Role in Industry

    In modern chemical manufacturing, each intermediate speaks volumes about the discipline of the people who make it. Carbamic acid comes up constantly in conversations about urethane chemistry, pesticide intermediates, and advanced polymer science. This isn’t a material that sits quietly on a shelf; it starts reactions. Anyone blending isocyanates or working on green pesticide initiatives has run the numbers and tracked down the small variations that only matter after years of trial and error. What customers ask for is a batch that does what the books say it will. We track every run, measure every batch, and look for the outliers. If a specification reads 98.5% minimum purity, we know that means zero leeway for downstream surprises. Each shipment faces off against the calibration curve before it leaves our facility.

    Daily Routine Meets Technical Detail: How Production Choices Shape Carbamic Acid

    A few years in, you stop seeing carbamic acid as a laboratory curiosity and start treating it as an industrial mainstay with a personality. Moisture sensitivity often complicates the work—ambient water vapor can throw off the entire batch profile, leading to decomposition, so we run airtight production lines with dehumidified air streams. Temperatures must stay within a tight band, since even a minor excursion can remake the product, driving hydrolysis or unwanted rearrangement, and producing volatile fragments that nobody wants. The operational controls look routine, yet each day brings its own challenges in balancing batch yield, finished purity, and safe handling.

    The team keeps detailed logs, not only for compliance but as a ledger of hard-earned adjustments collected across years of small incidents and quick recoveries on line. For example, shifts in batch mixing speed can influence the distribution of carbamic acid in suspension; minor tweaks on our reactors have gradually brought down the average deviation by a few tenths of a percent. That's the margin that turns repeat customers into partners.

    Specifications as the Result of Real-World Demands

    Industry-standard specs do not grow out of thin air—they rise from negotiations, laboratory testing, and enough case studies to fill shelves. Our technical staff document not just target assay values, but trace impurity limits, particle size ranges, and storage recommendations. These decisions reflect hard realities. Carbamic acid’s known instability at room temperature prompts us to prioritize small-lot deliveries and cold-chain logistics whenever possible. Moisture analysis comes built into every batch scan, and cross-contamination risk receives more attention than the books suggest. Hydrogen ion content, free acid quantification, and gas-phase byproduct checks stand at the core of our final release protocol.

    Downstream customers, whether they focus on pharmaceuticals, specialty resins, or crop protection formulas, see direct impact from even minor variances. A standard request may specify crystalline or powder form with less than 50 ppm of urea byproduct—a figure we track with both online analytics and classic wet-chemistry titrations. Particle size distribution can seem trivial in theory, yet in practice it affects mixing, reactivity, and safety when using our product for solid blends. Feedback loops from our partners provide the strongest signals: minor changes in moisture or particle sizing have previously led entire production lines off schedule or created performance issues in end-use.

    Distinction from Other Bulk Chemicals and Competitive Products

    Real differences between carbamic acid and competing intermediates show up in both chemical behavior and manufacturing intricacy. Isocyanic acid, for example, shares a similar elemental makeup but reacts wildly under standard conditions—harder to store, even tougher to transport without loss. Urea, another common industry staple, offers superior stability but lacks the direct reactivity needed in certain synthesis protocols, especially where selective functionalization or rapid decomposition under defined conditions is desired.

    Carbamic acid acts as a convenient starting point for constructing urethane linkages, especially when the pathway has to minimize byproducts or avoid secondary amines. Producers working with ethyl carbamate or more exotic carbamates often prefer the acid for in-house conversion, letting them tune the final product’s characteristics precisely, instead of relying on third-party blends. In hydrogen-bonding applications and scenarios demanding controlled breakdown, its intrinsic instability becomes an asset when handled correctly.

    Comparing quality from different producers, the devil lies in the process story—raw material provenance, process safeguards, analytically verified purity, and years of minor operational tweaks rather than boasts about “ISO this or that.” Our plant’s audit trail includes production temperature profiles, feed rate data, impurity logs, and post-run thermal stability studies that get updated with every process change. Ask our quality control team for the story behind any number on our certificate, and they’ll walk you through it from raw material truck delivery to sealed drum for shipping.

    Everyday Realities in Handling and Usage

    Making or handling carbamic acid for any length of time leaves a mark on how you think about chemical safety and shelf life. This isn’t to scare anyone off—just to repeat what everyone learns after enough handled drums, sampled batches, and cleaned vessels. Formulators realize very quickly the importance of keeping stock under dry, cool, and oxygen-poor conditions. Even brief mistakes, such as a couple of hours at ambient humidity, can degrade the contents or create clumps that resist redispersion.

    One customer in the crop protection sector shared how unopened drums stored in a humid warehouse saw a measurable decline in conversion yield after only a few weeks, a finding that has shaped our own storage and shipment methods. Today, our logistics team lines up insulated, moisture-sealed containers and schedules just-in-time deliveries based on actual consumption rates at the user’s facility. We train warehouse staff to recognize early warning signs of degradation, such as shifts in granule color or caking, and offer technical bulletins with troubleshooting advice adapted from our own experiences.

    Routine sampling, both prior to shipping and at customer sites, confirms batch integrity across the entire supply chain. Some of our customers take advantage of on-site analytical support; our chemists arrive with portable spectroscopic tools and reference standards, ensuring no unpleasant surprises disrupt their production—or ours.

    Lessons from Decades on the Production Line

    Carbamic acid’s technical difficulties leave no room for complacency. It rewards manufacturers who embrace the granular details: water management, thermal stability, and batch tracking. Our longest-serving operators can tell the difference between a batch cut short by five minutes or a lot exposed to a slightly off-kilter nitrogen blanket. Such nuances go beyond textbooks—the routines and safeguards protecting batch quality were built from incidents that rarely make it into published case studies.

    Every process upgrade, from switching filtration media to refining pre-charging regimens or calibrating drying cycles, finds roots in a specific troubleshooting episode. We lost an entire weekend’s production some years ago to a minor valve leak, an episode that prompted introduction of a triple-check regimen and real-time vapor detection. Teams that learn these lessons together shape not only the product, but also the institutional culture. Working closely with end-users, our technical staff swap war stories and improvement notes during joint troubleshooting sessions. Solutions often emerge not from management, but from a shift supervisor or a lead maintenance technician comparing notes with a plant process chemist.

    Building Trust: Our Commitment to Consistency and Transparency

    Buyers of intermediates like carbamic acid aren’t just investing in raw material—they’re trusting a team to safeguard their own production and reputation. Over the years, our customers have learned we answer the phone late at night and show up on-site if a batch doesn’t perform as promised. Product documentation packs aren’t just checked boxes for an auditor; every release goes out with full supporting data. On top of the COA, we include batch processing logs, representative chromatograms, and—at request—access to retained reference samples.

    Genuine transparency takes more than a polished website. Every chain in our IT and QA infrastructure aims to give customers confidence that what they see in their incoming drums matches what our production floor sees in its final batch records. No algorithm replaces shared knowledge traded face-to-face during a plant visit or troubleshooting call.

    Clients from resins to propellants, agrochemical blends to medical research centers, ask for details unique to their own downstream systems. They aren’t interested in boilerplate specifications; instead, they want context—how does this batch compare to last year’s, what are the byproduct signatures, and how flexible are we on custom filtration or particle sizing? We have no interest in brushing aside these questions. The closer the cooperation, the more both sides stand to gain.

    A Manufacturing Perspective on Carbamic Acid’s Future

    Track the supply landscape for a few years and you start to notice cycles: disruptions in ammonia or CO2 pricing, regulatory changes on downstream nitrogen compounds, or supply shocks in transportation. The team cycles through contingency plans and suppliers, but not at the expense of final batch quality. In recent years, greener process options have come up more often—processes that push for lower energy footprints or use renewable feedstock without sacrificing batch consistency. We’ve invested in R&D to keep up, sometimes co-developing closed-loop solutions with our biggest partners.

    Customers with specific needs get early access to pilot samples or run evaluation batches parallel with our production. Results feed back directly into process improvements, making every line of feedback part of the plant’s operational DNA—not just entries in a suggestion box.

    Our production approach has adapted as markets shift toward traceability, environmental metrics, and higher reporting standards. We see every request for greener logistics, recycled solvent use, and new packaging formats as a learning opportunity. These investments don’t exist separately from batch production—they are part of the flow, influencing everything from raw material intake to waste stream management.

    Where Performance Meets Partnership

    From daily test results to years of feedback, carbamic acid stands as both a technical achievement and testament to what manufacturing expertise can deliver. The lessons learned on our floor—about moisture control, process integrity, and customer trust—shape every shipment, every redesign, and every spec. We do not aim for a faceless commodity output. Instead, we work for reliability, traceability, and responsiveness that customers can count on not just for a single order, but through the ebbs and flows of their own industries. Our job is to deliver more than just a product; it’s to be the steady technical partner at the core of countless innovations downstream, learning and improving together through every batch and every collaboration.