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Bromooctane

    • Product Name Bromooctane
    • Alias 1-Bromooctane
    • Einecs 211-669-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    844850

    name Bromooctane
    IUPAC_name 1-Bromooctane
    CAS_number 111-83-1
    molecular_formula C8H17Br
    molar_mass 193.13 g/mol
    appearance Colorless liquid
    density 1.12 g/cm3
    boiling_point 206-208 °C
    melting_point -65 °C
    refractive_index 1.443
    flash_point 91 °C
    solubility_in_water Insoluble

    As an accredited Bromooctane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Bromooctane is supplied in a 500 mL amber glass bottle with a secure screw cap, labeled with hazard warnings and identification details.
    Shipping Bromooctane should be shipped in tightly sealed containers made of compatible materials, clearly labeled, and protected from heat and ignition sources. It is classified as a hazardous substance and should be transported according to local, national, and international regulations for flammable liquids, ensuring proper ventilation, spill containment, and emergency response measures during transit.
    Storage Bromooctane should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizing agents. Containers must be tightly closed and clearly labeled. Store in a flammable liquids cabinet if possible. Protect from sunlight and moisture, and follow all relevant safety regulations for handling and storage of hazardous chemicals.
    Application of Bromooctane

    Applications of Bromooctane in Industrial Manufacturing

    Bromooctane serves as a specialized alkyl halide, supporting a range of downstream production sectors. Our experience as a direct manufacturer ensures optimized usage and controlled specifications for each industrial segment. The following application scenarios reflect real B2B markets where Bromooctane integrates into differentiated manufacturing processes.

    1. Pharmaceutical Intermediate for API Synthesis

    Bromooctane functions as a critical alkylating reagent in the multi-stage synthesis of certain active pharmaceutical ingredients, primarily for the development of anti-infective compounds and neuronal agents. Downstream drug manufacturers utilize its reactivity to construct complex molecular scaffolds where an octyl chain introduction is required. Production must observe controlled reaction conditions to ensure purity, minimize byproducts, and enable consistent yields according to target molecule requirements. Material tracing, batch consistency, and compliance with regulated impurity profiles remain essential throughout the process.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) guidelines
    • European Pharmacopoeia (Ph. Eur.) monographs (where specified)
    • US FDA cGMP (21 CFR parts 210 & 211)
    • OECD chemical safety assessments

    Typical usage ratio

    • 0.8 to 1.5 molar equivalents per target intermediate, adjusted according to reaction yield optimization and final impurity limits

    Downstream process integration

    • Incorporated during the nucleophilic substitution or alkylation step within multi-stage small molecule API synthesis
    • Reacted under controlled temperature and inert atmosphere in high-purity glass-lined reactor systems
    • Intermediate isolated for further steps or purification

    Final product types

    • Anti-convulsant drug APIs
    • CNS agent intermediates
    • Alkylated bulk pharmaceutical chemicals

    2. Surfactant and Quaternary Ammonium Compound Manufacturing

    Bromooctane acts as an essential alkylating agent in the production of quaternary ammonium compounds with medium-chain hydrophobic groups. Surfactant producers employ it to synthesize cationic surfactant molecules characterized by effective antimicrobial activity or specialized emulsification properties. Manufacturing processes need precise feed rates, close monitoring for remaining bromide, and compliance with regional chemical safety legislation. Suitability for cosmetic and cleaning applications depends critically on residual reactant control and downstream purification.

    Industry compliance standards

    • REACH (EC Regulation No 1907/2006)
    • EPA TSCA for new chemical notifications
    • ISO 9001:2015 for quality management systems
    • EU Cosmetics Regulation (EC) No 1223/2009, if surfactants are for personal care products

    Typical usage ratio

    • 1.0 molar equivalent relative to tertiary amine substrate; small excess (up to 1.1 eq) to drive completion and maximize quaternization yield

    Downstream process integration

    • Reacted with relevant tertiary amines in solvent at 40–80°C for phase transfer or direct synthesis of quaternary ammonium salts
    • Crude product washed and recrystallized to meet specification

    Final product types

    • Octyltrimethylammonium bromide surfactants
    • Bactericidal cleaning agents
    • Phase transfer catalysts

    3. Agrochemical Synthesis Chain

    Agrochemical manufacturers utilize Bromooctane primarily as an alkylating precursor in the production of octyl-based insecticides and fungicide intermediates. Beyond reactivity, careful process design manages the conversion steps to limit impurities, comply with residue definitions, and safeguard final product registration with agricultural authorities. Excess unreacted bromide must be fully removed before product formulation to satisfy field safety and application regulations.

    Industry compliance standards

    • FAO/WHO specification for pesticide technical materials
    • OECD Guidelines for the Testing of Chemicals
    • ISO 17025 for accredited analytical laboratories
    • National registration dossiers (EPA, EU PPP Regulation EC No 1107/2009, or China's ICAMA)

    Typical usage ratio

    • 0.95–1.2 molar equivalents as determined by desired alkylation yield and selectivity for target pesticide intermediate synthesis

    Downstream process integration

    • Introduced during the chain extension or substitution step within multi-step agrochemical active ingredient development
    • Purification by acidic wash and vacuum distillation to remove organobromine byproducts

    Final product types

    • Octyl-substituted insecticide actives
    • Intermediate agrochemical building blocks

    4. Organic Synthesis Building Block in Performance Chemicals

    Specialty chemical companies employ Bromooctane as a source of octyl groups in the production of lubricants, flow improvers, and functional additives. The alkyl chain length and reactivity enable its use in the fine-tuning of hydrophobic/lipophilic balance for additives required in plasticizers, synthetic esters, and functionalized resins. Strict feedstock identity confirmation and continuous process monitoring ensure end-product performance, compliance with final use regulations, and consistent batch reproducibility.

    Industry compliance standards

    • ISO 14001 Environmental Management System
    • Global Automotive Declarable Substance List (GADSL) – for automotive additive applications
    • REACH (EC Regulation No 1907/2006) registration for downstream chemical use
    • Customer-specific specification sheets

    Typical usage ratio

    • 1.0 equivalent in functional additive synthesis; exact ratio adjusted for performance property targets and chain incorporation efficiency (typically 3-8% w/w in polymer additive applications)

    Downstream process integration

    • Employed in alkylation, esterification, or substitution steps for specialty product synthesis
    • In-line QC checkpoints for hydrocarbon purity and residual bromine

    Final product types

    • Synthetic lubricants (PAO-based)
    • Polymer flow agents
    • Lipophilic resin additives

    5. Research and Laboratory Reagent Supply

    Chemistry and pharmaceutical laboratories order Bromooctane as a defined alkylating reagent for small-scale synthesis, structural modification studies, and early-stage compound library expansions. Laboratories require defined purity grades, complete analytical data, and transparent origin documentation for regulatory and experimental repeatability purposes. Material must be packed, labeled, and shipped according to chemical safety rules relevant to research institutions and universities.

    Industry compliance standards

    • Analytical grade requirements as per ACS or ISO 6353-1
    • UN 2810 hazardous goods regulations (DG shipping)
    • GLP (Good Laboratory Practice) guidelines
    • Material Safety Data Sheet (MSDS) compliance per OSHA requirements

    Typical usage ratio

    • As required by individual experiment (0.1–5 mmol scale), depending on stoichiometry and targeted transformation

    Downstream process integration

    • Added at the designated step in exploratory or method development reactions
    • Batch record and analytical data supplied to support traceability

    Final product types

    • Custom small molecule libraries
    • Alkylated building blocks for medicinal chemistry
    • Reference materials for analytical validation
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    Certification & Compliance
    More Introduction

    Bromooctane: A Manufacturer’s Perspective on Quality, Versatility, and Application

    Direct from the Source: Our Approach to Bromooctane Production

    At our chemical plant, every batch of Bromooctane reflects years of hands-on experience with alkyl halide synthesis. We operate with a practical focus on consistency, traceability, and purity. As a manufacturer, the first concern is always the raw material. Access to high-purity 1-octanol and clean hydrobromic acid provides a good starting point, but that’s only part of the equation. The process matters just as much—the distillation step determines whether the end-user sees clean color and stable purity, not just numbers on a certificate. Bromooctane needs to meet a specification that fits organic synthesis, not just generic solvent use. That means chasing down every trace impurity and controlling the reaction environment with proper process control.

    Our model centers on 1-Bromooctane, the straight-chain, eight-carbon alkyl bromide. The molecule’s structure—C8H17Br—offers a balance between reactivity and manageable handling. Longer chains such as 1-bromodecane or 1-bromododecane can get unwieldy with volatility and viscosity, but shorter chains like 1-bromopropane and 1-bromobutane introduce health and safety complications in the workplace and the environment that just don’t belong in fine chemistry routes anymore. With mid-length chains like octyl bromide, facility air and ground pollution controls work more efficiently, as the volatility sits right in a safer window.

    Specifications Rooted in Real Production Environments

    Time in the reactor and attention in purification shape every liter we supply. Our Bromooctane usually goes out at a purity no lower than 99%, as verified by GC with a focus on limiting chlorinated or other halogenated byproducts. Trace amounts of residual water and acid matter in most downstream reactions, so all bottling runs through a controlled drying and filtration step before filling. Color stability, even in bulk storage, comes down to good separation of the reaction product from leftover reagents. In large-scale plant use, these impurities may not show up right away, but anyone who has seen a process grind to a halt thanks to an off-color, off-odor batch knows the risk of cutting corners.

    Packing and delivery focus on seamless integration with user operations. Bulk product for industrial customers ships in lined drums or IBCs, which guard against corrosion and contamination. Small-batch research partners, especially those in pharmaceuticals and advanced materials, receive glass or Teflon-sealed containers to avoid any hint of interaction between packaging and chemical. Over the years, close feedback loops with customers have pushed us to refine not just raw purity but also packaging practice—capping, sealing, and even labeling become a point of pride when the goal is reliable scale-up.

    End-User Applications: Chemical Synthesis and Beyond

    Bromooctane’s most frequent use shows up in the creation of specialty surfactants, phase-transfer catalysts, and as a C8-building block in pharmaceutical chemistry. In-situ alkylation reactions require reliable starting material. We have worked directly with teams who have run Grignard reactions and looked for tight control of halide reactivity, often noting that even minor deviation in the alkyl bromide grade can cascade into yield losses or product impurities. Some research groups in the field of ionic liquid discovery lean towards Bromooctane as a customizable tail in designing solvent systems or antistatic agents for coatings. If you’re scaling to production levels in these processes, you find that contaminants from inconsistent production end up locked in the final material. That leads to headaches in quality control or—worse—expensive rejection of finished product.

    Another key group of users comprises companies developing organic intermediates for agrochemicals and advanced paints. The straight-chain structure brings both lipophilicity and consistent reactivity, which can be missing in alternative alkyl halides. That property lets formulators introduce long hydrocarbon tails in molecules for improved solubility or environmental transport properties. We have seen chemists pivot away from shorter or more volatile alkyl bromides as they move to cleaner technologies—Bromooctane’s chemical profile matches both worker safety and strict product performance standards.

    The Difference Experience Makes in Output

    Many are quick to lump all alkyl bromides together. In reality, every chain length and substitution pattern brings its quirks. Eight carbons in a straight line, as we engineer it, hit the sweet spot for manageable viscosity, moderate reactivity, and ease of post-reaction workup. For anyone in the lab or plant, the distinction isn’t just academic. For example, branch-chain bromooctanes often feature higher boiling points and different physical handling properties, complicating distillation and recovery steps in scale-up. We stick with 1-Bromooctane for reliability, lower haze formation in final blends, and a clear path for follow-up chemical transformations.

    Our facility dedicates itself to fighting batch-to-batch variance, remembering past issues with unstable intermediates stemming from inconsistent chain distribution. By sticking to straight-chain feedstocks, we've helped not just our own teams but those downstream prevent a lot of unpredictable behavior in later stages of synthesis. The result has been less waste, fewer delays in complex multi-step reaction schemes, and a higher level of trust between chemists on both ends of the supply chain.

    Handling, Safety, and Sustainability in Practice

    Anyone who manages a chemical plant knows that safety goes far beyond what’s printed on an SDS. Our own protocols for handling Bromooctane came from years spent seeing where the points of failure show up—be it in loading, unloading, or in clean-up after a minor incident. Bromooctane’s moderate volatility means fume extraction and well-sealed transfer lines minimize exposure risks better than either more volatile short-chain bromides or the sticky, hard-to-handle longer chains. Over time, process safety studies have nudged us towards tighter control of handling environments. We reduced open transfer points and implemented rigid personal protective gear rules to keep our teams healthy and safe, especially during drum-filling and excess reactant recycling operations.

    On the environmental side, residual brominated wastes demand rigorous treatment before leaving the plant. We have invested in specialized neutralization and bromine recovery units to prevent any release to sewer or air. Recent years brought extra scrutiny from local inspectors, so we review waste streams weekly, both to check compliance and to find recoverable value in what might otherwise become an environmental liability. Being able to tell customers the product comes from a plant running cleaner and safer becomes a strong motivator, not just a box to tick for audits.

    Why Bromooctane Instead of Alternatives?

    In direct discussion with our clients in synthesis and formulation, questions often turn toward why Bromooctane holds its place while the industry pushes for “greener” or less hazardous substances. Looking at C8H17Br, the molecule offers precise control for nucleophilic substitution, and the hydrophobic tail fits many applications seeking to impart flexibility or improve compatibility with nonpolar environments. Compared to 1-chlorooctane or shorter bromides, octyl bromide provides more predictable yields, fewer hazardous byproducts, and non-negligible advantages in process throughput. Our decision to focus production capacity on Bromooctane rather than splitting lines with less efficient alternatives comes down to this reliability.

    Some argue for moving towards sulfonates or other leaving groups, but process experience tells a different story. We’ve conducted side-by-side industrial trial runs, and while sulfonates suit lab-scale projects, their cost and downstream residue profiles create hurdles in production-level manufacturing. Bromooctane wins out in the real world due to robust performance, tighter product specs, and smoother plant operation. That focus means streamlining maintenance, reducing unplanned process interruptions, and guaranteeing product quality from receipt of order to offload at a customer site.

    Supporting Real Projects, Not Just Lab Work

    Working with industrial and research users for years, we keep seeing the same theme: project delays and failed syntheses so often trace back to poor or inconsistent raw materials. Bromooctane that varies in color, contains trace aromatics, or absorbs moisture ends up fouling up plans—whether that's a 200-liter scale-up run at a pharma plant or a specialty polymer batch. We spend time talking not just to purchasing teams but the chemists themselves, adjusting shipment sizes, packaging types, and delivery timelines. In a tight-margin business, flexibility and reliability in delivery take on the same importance as specification sheets.

    Research institutions developing new drug molecules or material coatings push the boundaries of what Bromooctane can do. They share data with us, and we respond by tweaking distillation processes or batch filtration. This open loop back to manufacturing adjusts our own operations, which means clients don’t need to push through unworkable variations or “work up” a solution that introduces cost and error. In practice, that means bottling at smaller scales, feeding back quality metrics, and even tracking storage temperatures through shipping. These aren’t value-adds on a spec sheet—they come from solving headaches that come up in the real world.

    Challenges and Solutions in Supply and Scale

    Global events and shifts in the regulatory landscape change how specialty chemicals move. Bromooctane buyers come to us not just for supply but for predictability. Supply chain disruptions during the pandemic and recent market price swings put reliability under stress. We’ve found the best way to respond involves direct sourcing of our raw octanol and hydrobromic acid, holding additional inventory against unpredictable swings, and doing more predictive maintenance on our reactor systems. This sits on top of close ties to our freight partners and investing in real-time inventory management.

    One challenge that doesn’t always get attention involves the swings in regulation on brominated compounds. Every time a new environmental rule lands, our technical team evaluates not just what it means on paper, but how it impacts day-to-day operation. We track waste output and emissions, and we maintain test results on finished product purity—so if a client faces an audit or export challenge, answers are ready and transparent. A lot of supply hiccups in specialty chemistry trace back to regulatory inconsistency, and as a direct producer, we act quickly, update processes, and give our clients better risk visibility.

    Continuous Learning, Continuous Improvement

    Running a plant that produces Bromooctane means never standing still. We adopt new analytical methods like high-resolution mass spectrometry or advanced chromatography as soon as practical experience shows their value. That plays out not just in batch QC, but in trend analysis—spotting subtle shifts in impurity profiles or performance metrics long before a customer’s line hits a problem. Being on the shop floor, we see the impact of even slight changes in raw material sources or seasonal temperature variations, so our approach involves error-proofing runs, logging parameters for traceability, and acting on feedback rather than assuming the lab result alone tells the whole story.

    We have seen big improvements in product quality by sharing raw data in near-real time with our partners. That goes for big customers running full-scale plants as well as smaller labs working on next-generation surfactants or bioactive molecular scaffolds. The investment comes in sensors, data connectivity, and a whole lot of training for operators and analysts. The payoff becomes clear every time we avoid a product recall or a reworking campaign that chews through resources.

    Looking Ahead: Bromooctane in Tomorrow’s Markets

    It pays to keep an eye on where technology is taking our main product. Demand continues strong in fields looking for eco-friendly solvent replacements and improved intermediate building blocks. More polymer chemists and pharmaceutical process teams adopt Bromooctane as the industry tightens up around quality, environmental profile, and regulatory compliance. We notice that each year, customers ask more questions about lifecycle analysis—how materials are made, how waste is handled, and how much energy the whole process consumes.

    In our shop, any move to scale or alter Bromooctane output gets run through a technical, safety, and environmental review. That means adopting new process routes, like integrating closed-loop bromine recycling, only after plenty of practical trial runs. Some clients worry about the regulatory future of brominated substances, and the dialogue leads us to pursue better purification, waste minimization, and downstream process audits. Ultimately, the product’s place in tomorrow’s market depends not just on chemistry but on real-world stewardship and a willingness to invest in processes that keep pace with evolving global expectations.

    Final Thoughts: Reliability Built on Practical Experience

    As a manufacturer, our reputation stands on reliable output and honest dialogue. Bromooctane isn’t just a catalog number to us—it’s a product honed by years in production trenches and by working side-by-side with real users. Specification sheets don’t solve process bottlenecks, but shared problem-solving does. For teams looking to scale up, tackle new synthesis challenges, or reduce rejects, the choice of Bromooctane goes beyond price or minimum purity—success depends on a manufacturer’s willingness to adapt, respond, and invest in quality every day. Our process is shaped not by one-off lab trials, but by real commitment to consistency from raw material all the way to delivered product.