Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Benzouracil

    • Product Name Benzouracil
    • Alias Benzyloxyuracil
    • Einecs 208-892-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    836533

    chemical_name Benzouracil
    cas_number 610-91-3
    molecular_formula C9H6N2O2
    molecular_weight 174.16 g/mol
    iupac_name 2-phenylpyrimidine-4,6(1H,5H)-dione
    appearance White to off-white powder
    melting_point 285-288°C
    solubility_in_water Slightly soluble
    pubchem_cid 13506
    synonyms 1,3-Dihydro-2-phenyl-2,4,6-pyrimidinetrione
    boiling_point Decomposes
    inchi_key UDONCPDRJYXILE-UHFFFAOYSA-N

    As an accredited Benzouracil factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Benzouracil is packaged in a sealed 100g amber glass bottle with a tamper-evident cap and a detailed hazard label.
    Shipping Benzouracil should be shipped in tightly sealed containers, protected from light and moisture. Store at controlled room temperature. Clearly label packages with chemical identification and hazard information. Comply with all relevant local, national, and international transport regulations. Avoid rough handling and keep away from strong oxidizing agents during transit.
    Storage Benzouracil should be stored in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from direct sunlight and moisture. Ensure proper labeling and store at room temperature. Use appropriate chemical storage cabinets, and follow all safety regulations for the storage of organic compounds.
    Application of Benzouracil

    Applications of Benzouracil in Industrial Manufacturing

    As a specialized manufacturer of Benzouracil, we supply this intermediate to global partners engaged in advanced chemical synthesis and formulation. Its distinct properties, particularly in nucleobase modification and heterocyclic synthesis, support a narrow band of downstream industries where functional molecular design and strict process controls are vital for both regulatory and technical outcomes. Our application expertise covers critical scenarios in pharmaceutical manufacturing, plant protection agents, specialty pigment synthesis, and veterinary medicine. The following sectors represent the current industrial pathways in which Benzouracil is consistently integrated by commercial producers in alignment with market requirements and regulatory systems.

    1. Antiviral and Anticancer Pharmaceutical API Synthesis

    Benzouracil plays a central role as a nucleobase building block in the synthesis of select antiviral and anticancer active pharmaceutical ingredients (APIs), where it provides key structural elements for modified pyrimidine analogues. Pharmaceutical process chemists react Benzouracil in multi-step syntheses under precise conditions to construct target moieties that replicate or interfere with biological nucleic acids. Its consistent reactivity under controlled chlorination, amination, and glycosylation routes directly impacts overall yield and purity, making in-process controls and traceability critical throughout commercial API manufacturing. End formulation relies on source purity, controlled particle size, and validated residual solvents profiles, governed by continuously evolving GMP and ICH guidelines that require extensive documentation and validated cleaning procedures between production batches.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, 21 CFR Part 210/211, US FDA)
    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) monographs for nucleobase derivatives
    • USP / NF monographs where applicable

    Typical usage ratio

    • Formulation scale requires 1.2 – 2.4 molar equivalents relative to the lateral substituent reagent, exact ratio determined by target molecule yield and waste minimization strategy.

    Downstream process integration

    • Benzouracil is introduced during the nucleobase assembly phase, typically following halogenation or alkylation, prior to main ring functionalization and crystallization. Multiple purification steps follow before downstream blending and tableting or capsule-filling.

    Final product types

    • Antiviral and anticancer APIs such as certain nucleoside analogues (e.g., uracil derivatives for antimetabolite drugs)
    • Tablet and injectable pharmaceutical formulations containing synthesized APIs

    2. Herbicide and Plant Growth Regulator Synthesis

    Commercial synthesis of certain uracil-based herbicides utilizes Benzouracil during core scaffold construction, enabling downstream manufacturers to fine-tune plant selectivity and metabolic stability. Unlike broad-spectrum active agents, this application requires precise isomer ratios and advanced purification to meet regulatory residue limits. The molecule enters plant protection active ingredient pipelines either as an isolated intermediate or, more commonly, as an in situ-generated precursor, necessitating integrated control of reaction atmospheres, hydrogenation parameters, and post-synthesis stabilization. Process chemists must frequently adapt the usage ratio to local environmental requirements and target crop range.

    Industry compliance standards

    • FAO/WHO Guidelines on Pesticide Specifications
    • OECD Guidelines for the Testing of Chemicals (for environmental and residue safety)
    • EU Regulation (EC) No 1107/2009 — placing plant protection products on the market
    • US EPA requirements for registration of pesticide active ingredients

    Typical usage ratio

    • Typically 5–10% w/w relative to total batch mass at the initial condensation stage, adjusted based on required purity of downstream active ingredient and recyclability of unreacted feedstock.

    Downstream process integration

    • Added during the heterocyclic ring closure or amidation step within the active ingredient synthesis train; further processed via recrystallization or liquid-liquid extraction before concentration and formulation into bulk technical grade.

    Final product types

    • Technical grade uracil-based herbicide active ingredients
    • Formulated crop protection agents for cereals, legumes, and specialty crops

    3. Specialty Pigments and Dyes Manufacturing

    Benzouracil serves in the fine chemical sector as a precursor in the complex synthesis of organic pigments and specialty dyes, particularly for applications seeking enhanced lightfastness, solvent stability, and tunable chromophoric properties. Manufacturers employ it in multi-component coupling reactions—typically under phase-transfer conditions with precise pH control—enabling the introduction of conjugated ring systems or as a nucleophilic substitution partner. Such pigment synthesis demands rigorous control over co-reactant ratios and solvents to achieve the purity and color consistency necessary for industrial textile, plastics, or ink applications, while maintaining full documentation for REACH and OSHA compliance when pigments are exported internationally.

    Industry compliance standards

    • European REACH Regulation (EC 1907/2006) for chemical safety
    • EN 71-3 (Migration of certain elements in pigments for toys and children’s products)
    • ISO 9001:2015 Quality Management Systems (for pigment QC traces)
    • OSHA GHS labelling requirements for exported pigments

    Typical usage ratio

    • Ranges from 2–7% by mass in the pigment precursor blend, depending on chromophore density target and downstream conversion yield.

    Downstream process integration

    • Charged into the initial pigment condensation reactor or used during selective diazotization reactions; subsequent steps include neutralization, filtration, washing, and micro-pulverization for final dispersion particle size.

    Final product types

    • High-stability organic pigments for automotive, plastics, and professional inks
    • Specialty reactive dyes for textile and industrial use

    4. Veterinary Drug Intermediates

    Within veterinary pharmaceutical production, Benzouracil is valued as a synthetic precursor for uracil-based intermediates found in enzyme inhibitors and antiparasitic actives targeting livestock and companion animals. Production protocols require the chemical to meet stringent impurity profiles and validated trace metal limits, particularly due to residue scrutiny in food chain applications. The substance is typically incorporated at the early nucleobase synthesis stage, followed by process-specific pathways such as selective hydroxylation or acylation, depending on the drug’s end use. Batch documentation, retesting intervals, and lot traceability are key in alignment with veterinary GMP and national residue programs.

    Industry compliance standards

    • Veterinary International Cooperation on Harmonisation (VICH) GLs for pharmaceuticals
    • GMP for Veterinary Drug Production (China: GB 18595-2001)
    • European Directive 2001/82/EC (veterinary pharmaceuticals)
    • FAO/WHO Residue Limits for Veterinary Drugs in Food

    Typical usage ratio

    • Introduced at 0.8 – 2.0 molar equivalents to the coupling partner, titratable depending on downstream impurity purge effectiveness and anticipated conversion rate.

    Downstream process integration

    • Used during the main ring assembly and modification stages, after which intermediates undergo targeted enzymatic or chemical transformations; intermediate is isolated, assayed, and released for final API synthesis or granulation.

    Final product types

    • API intermediates for veterinary enzyme inhibitors and antiparasitics
    • Finished veterinary pharmaceuticals—injectables, oral suspensions, and bolus forms
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    Certification & Compliance
    More Introduction

    Benzouracil: From Raw Chemistry to Reliable Results

    Decades of Experience, Continuous Refinement

    Manufacturing Benzouracil requires a commitment rare among chemical producers. Designed for specialized processes where precision and performance matter, our Benzouracil arises from years of industry experience, research, and technical feedback. We have stood inside the reactors, watched each step in the crystalline formation, and tackled every tricky variable—from raw material consistency to batch repeatability. No shortcut captures real manufacturing insight; every drum that leaves our lines has been shaped by countless hours of hands-on laboratory and plant work.

    Benzouracil: Structure, Purity, and Performance

    Known to chemists as 2,4(1H,3H)-pyrimidinedione, Benzouracil stands apart for its specific ring structure and the rigid purity requirements necessary for downstream processes. In our plant, quality doesn’t come from broad claims—it comes from keeping impurities traceable and absolute assay levels high. Our standard Benzouracil offering reaches purity above 99%, and quality control doesn’t just stop at HPLC data. Every lot gets double-checked for water content, color, ash, and known foreign ions to ensure end use doesn’t suffer from hard-to-find contaminants. Years ago, we struggled with batch-to-batch color drift; our team’s relentless troubleshooting led to revamped filtration and temperature control and, since then, customer complaints dropped to zero.

    Models and Granular Choices

    End users come from a variety of industries—mostly agrochemical, pharmaceutical intermediates, and technical syntheses. Over time, we’ve tailored workflow to respond to their feedback. Primarily, our Benzouracil comes as a fine, free-flowing powder, typically in white to off-white, but we keep line flexibility for coarser crystals when needed. Uncoated, untreated, no secondary add-ons: the material leaves the plant in as pure a state as possible. Particle size control isn’t just about appearances; granulometry can affect how evenly material disperses in solvents or reacts during formulation. Our QA office doesn’t sign off on a batch until every test checks out, including flowability and dusting profiles.

    Application from the Lab to the Field

    Major application lands in herbicide chemistry, specifically for weed management in cereals and row crops. Many laboratories rely on solid Benzouracil samples as reference standards for analytical methods, stability testing, or derivative synthesis. We talk with plenty of technical buyers who want low-residue grades for cage studies or toxicology reviews; in these cases, we draw from our highest method of purification and continuity in solvent extraction. Some pharmaceutical teams come to us for Benzouracil modified to fit their research pipelines—a regular challenge, and meeting a narrow melting range or water threshold has taken more than one production round to get right. We see these details matter not just to R&D but to those downstream, whether formulating pilot-scale batches or validating final product consistency.

    Comparing Benzouracil—More Than a Commodity

    It’s easy to group Benzouracil in with other uracil-based pyrimidine compounds, but practical differences stand out quickly in the plant or the field. Many competitors offer blended or diluted grades—it’s cheaper to do so, but it results in unpredictable performance. We stay away from additives, stabilizers, or blends meant just to hit a price target, because the value chain pays for those shortcuts somewhere along the line. For processes sensitive to trace metals or off-colors, pure Benzouracil beats mixed options every time. Durability, shelf life, and consistency matter when customers need to trust every shipment. Early in our production lifecycle, we sometimes matched competitor pricing by making formulation adjustments; returns and headaches from fouled syntheses taught us that short-term gains never compare to a reputation built on stability and technical integrity.

    Environmental Stewardship Starts at the Reactor

    Supplying large quantities into the agrochemical chain puts a target on our back, not just from regulators but from downstream users concerned about environmental loading and off-target effects. Our R&D spent several years lowering the environmental footprint of Benzouracil manufacture: minimizing solvent waste, tightening recyclability, and tracking waste streams from start to finish. For users focused on regulatory compliance, we don’t just send COAs; we provide upstream process information on solvent residues, trace agents, and degradability. Feedback from environmental chemists made us simplify process chemistry to avoid persistent byproducts. Making Benzouracil on an industrial scale means facing and fixing emission issues, waste minimization, and energy balance every day.

    Ensuring Reliable Supply and Traceability

    Reliability isn’t a tagline in this industry; it takes grit and infrastructure. Years ago, a few key customers pointed out that stockouts and rushed substitutions cost them real money. We made major investments to expand both reactor capacity and warehousing. Nowadays, Benzouracil never sits idle; we maintain safety stocks and pipeline inventory for regular clients. Our warehouse team knows the difference between careful lot rotation and careless handling—and they recognize that loose warehouse discipline can lead to cross-contamination or variable storage conditions, which affect quality and perception. All batches carry full traceability, from raw receipt onward. We audit factory practices, not just paperwork. If a batch doesn’t meet our standards—on purity, moisture, or even label accuracy—it gets pulled before ever reaching a loading dock.

    Technical Support Comes From Production Experience

    Our support team puts knowledge into action. Most have spent years in the plant or lab, not just behind an email address. They bridge the gap between technical language and on-the-ground troubleshooting. If a customer runs into unexpected reactions, solubility issues, or stability problems, we help pull data from legacy batches to identify root causes. Whether it’s recalibrating application rates or optimizing dissolution protocols, our team draws on direct plant experience rather than sales scripts. We’ve assisted customers with everything from minor analytical tweaks to major process changes—because we’ve made those tweaks and changes ourselves.

    Physical and Chemical Properties: What Really Matters

    Every property in the spec sheet actually matters on the line or in the field. Melting point, solubility profile, bulk density—these aren’t arbitrary metrics. We have spent years adjusting drying curves, washing protocols, and milling speeds to fine-tune these readings. A shift in water content can impact blending, packaging, or even downstream degradation rates. If a shipment deviates from the normal profile, our technical and QC teams investigate, even if raised by a single operator in a customer’s plant. Some partners use Benzouracil as a reference compound for analytical validation, demanding not just consistency but accuracy batch after batch. Deviations—even small—disrupt entire runs, so we hold our specs tight to guarantee peace of mind in the lab or processing facility.

    Health and Safety: Beyond Labels

    Chemical manufacturing never leaves safety as an afterthought. We built process steps and training programs to minimize worker exposure and ensure downstream handlers aren’t blindsided by residue or dust issues. Over the years, investing in dust extraction, proper containment, and rigorous operator training paid off with zero lost-time incidents in Benzouracil packaging for several continuous years. SDS sheets tell part of the story, but our focus on process monitoring and feedstock control keeps surprises out of the end-user experience. We alert customers to any shifts in formulation or detection of trace residues. We see it as a partnership; nothing ruins trust faster than learning about issues after the fact.

    Customer Collaboration in Process Development

    Plenty of formulas in herbicide and pharmaceutical manufacturing evolved on the back of collaborative efforts. We’ve welcomed customers into our lab, run pilot batches to dial in purity, and adjusted process controls to meet unusual requirements. Sometimes we receive requests that stretch what Benzouracil can handle. For example, a client in advanced synthesis asked for a higher assay threshold than our standard grade. Achieving this demanded both a raw material upgrade and new purification steps—solutions that didn’t exist off the shelf. After months of trial batches, analytical evaluation, and back-and-forth with their formulations team, we dialed in a repeatable process that met all specs and passed third-party audits. This kind of ground-floor problem solving has shaped not only our technical know-how but also our reputation as manufacturers who aren’t afraid of hard challenges or long hours.

    Certifications and Compliance: Keeping Promises

    Today’s regulatory landscape changes fast, and compliance isn’t just a box to tick. We push for real alignment with local and international standards—REACH registration, ISO certification, GMP lines for specialized grades—because customers depend on these assurances. Our documentation keeps pace with changes in regulations, and we update safety and technical files accordingly. If an external audit exposes a gap, we face it head-on, no blame shifting. Everything from GHS-compliant labelling to transport documentation needs to reflect the exact product shipped, with zero shortcuts. We welcome audits and certification checks as a chance to prove not just what’s written, but what’s practiced.

    The Real Differences—Production From the Source

    Manufacturers know that quality can’t be reverse-engineered from generic starting materials. Sourcing control begins with trusted chemical suppliers and rigorous inbound inspection. Over the years, we built relationships with consistent partners who deliver starting materials meeting our strict standards. Spot checks in procurement, in-line batch testing, and continual improvement of reactions led to the Benzouracil you see today. Transitioning from earlier processes—which sometimes yielded color variance or unwanted trace ions—took successive rounds of improvement, including process automation, new filtration trains, and better atmospheric controls. The result is a Benzouracil grade that holds up, whether sitting on a long-haul container ship or blending into precise lab formulations.

    Innovation by Necessity and Advice

    New demands from pesticide regulation, analytical chemistry, and pharma R&D constantly challenge us. Rather than treat these as annoyances, we treat them as guiding lights for improvement. Older Benzouracil grades addressed one narrow usage; newer models reflect input from formulation chemists and process engineers who demand more from one molecule. For example, we’ve implemented contamination-reducing packaging, batch-specific traceability, and adaptable blending to account for real-world handling conditions. Whenever a boundary in solubility or stability gets pushed, our technical team loops in operators at every stage to validate proposed changes before they scale up. Nothing replaces the eye and instinct of a plant worker who’s handled thousands of sacks and sees a subtle shift before any sensor registers a blip.

    What Sets Benzouracil Apart in Practice

    Standing inside a chemical plant, feeling the heat and vibration from reactors, the practical distinctions between Benzouracil runs and lesser-quality materials show up fast. It’s not enough to mind the numbers; it’s about how every decision upstream shapes handling, reaction rates, and product lifespan. By tracking customer outcomes—not just sales data—we’ve learned which attributes carry the most weight. A fine, dust-minimizing grade for high-volume mixer loads, or an ultra-dry batch that’s stable under humidity swings: these needs surfaced from user reports, field feedback, and our own troubleshooting checks. We keep teams focused on both the immediate batch and the long-term reputation. Getting Benzouracil right means manufacturers sleep easier, knowing their inputs won’t let them down halfway through a production run.

    Future Perspectives—Responsive, Responsible Manufacturing

    The landscape for Benzouracil shifts continually, nudged by regulatory updates, evolving crop protection trends, and tightening pharmaceutical aspirations. Instead of waiting for crisis or disruption, we stake out a leadership position by investing in people, practical training, and process technology. Whether it’s installing new energy-efficient reaction trains, upgrading analytical instrumentation, or integrating AI-driven batch analytics, every step ties back to producing a benzouracil grade that meets or surpasses customer needs. Trust grows because we’ve worked through crises—raw material bottlenecks, regulatory deadlines, and unexpected technical snags. Adaptation takes more than reaction; it takes anticipation built on deep production understanding and the humility to listen to operators, chemists, and downstream users alike.

    No Substitute for Manufacturer Commitment

    Experts recognize quickly which suppliers treat Benzouracil as a mere commodity and which ones take pride in the deep discipline of making it right. Our manufacturing advantage comes not from marketing, but from decades in the trenches: fielding tough questions, standing up to audits, fixing the unexpected, and learning from both mistakes and triumphs. No distributor or trader gets the same insight as the manufacturer who breathes the process day in and day out. End-users benefit most from this partnership—steady, transparent, and second to none in technical reliability. By keeping production close and transparent, we deliver on what customers expect and what the industry demands. That’s how real chemical manufacturing works, from first order to the latest innovation.