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5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole

    • Product Name 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    276813

    Productname 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole
    Casnumber 881674-56-6
    Molecularformula C10H5Cl2F3N3S
    Molecularweight 328.14 g/mol
    Appearance Light yellow to yellow powder
    Meltingpoint 165-170°C
    Solubility Slightly soluble in DMSO, insoluble in water
    Purity ≥98%
    Storageconditions Store at 2-8°C, protect from light
    Smiles C1=CC(=C(C(=C1Cl)Cl)C(F)(F)F)N2C(=C(C=N2)N)S
    Synonyms N/A

    As an accredited 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle with tamper-evident seal, labeled for 25 grams, featuring hazard symbols, chemical name, batch number, and manufacturer details.
    Shipping The chemical 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)pyrazole is shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. Transportation follows regulations for hazardous chemicals, ensuring proper labeling and documentation. Handle with care, avoiding extreme temperatures and mechanical shock, and comply with all local, national, and international shipping guidelines.
    Storage Store 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)pyrazole in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from light and moisture. Properly label the container and ensure access is limited to trained personnel, following standard chemical storage guidelines and relevant safety data sheet (SDS) recommendations.
    Application of 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole

    Purity 98%: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole with 98% purity is used in pharmaceutical intermediate synthesis, where high purity ensures consistent yield and reduced by-product formation.

    Melting Point 185°C: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole with a melting point of 185°C is used in high-temperature organic reactions, where thermal stability allows for precise reaction control.

    Particle Size D90 < 10 µm: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole at particle size D90 < 10 µm is used in advanced agrochemical formulations, where fine particle distribution enhances bioavailability.

    Moisture Content < 0.5%: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole with moisture content below 0.5% is used in dry powder formulations, where low moisture prevents caking and degradation.

    Stability Temperature 120°C: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole with stability temperature up to 120°C is used in polymer modification processes, where chemical stability supports long processing cycles.

    Solubility in DMSO > 10 mg/mL: 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole with solubility in DMSO greater than 10 mg/mL is used in biological assay development, where high solubility enables accurate dosing and reproducible results.

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    Certification & Compliance
    More Introduction

    Introducing 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole: Building Trust Around Innovation

    Why One Compound Shapes So Many Possibilities

    Breaking down complex chemistry for real-world impact is never about buzzwords. It’s more about seeing how a single molecule changes the way scientists, researchers, and entire industries solve tough challenges. 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole steps into the spotlight as a specialty compound, not because of hype but based on genuine contributions to modern process development—especially where precision and purity matter most.

    What Makes This Pyrazole Variant Stand Out

    Not every pyrazole derivative carries the clout of this one. The presence of amino and mercapto groups brings together nucleophilic reactivity with sulfur's well-known binding character. The dichloro and trifluoromethyl substitutions on the phenyl ring add a step up in chemical resistance and influence both electron distribution and stability. This makes the molecule sturdy in harsh chemical environments while keeping its edges sharp for downstream modification.

    Lab veterans know that electronic effects from chlorine and trifluoromethyl have a way of making aromatic compounds less prone to unwanted side reactions. Scientists looking for predictability and robust baseline activity choose this molecule for its performance in synthesizing advanced heterocyclic compounds and for fine-tuning pharmaceutical intermediates. Compared to simpler pyrazole structures, this compound provides both an anchor for synthetic flexibility and a shield against degradation or inconsistent results.

    Clarity On The Audience That Relies On Purity

    It’s one thing to sell a specialty chemical, it’s another to understand who depends on it. Across pharmaceutical, agrochemical, and specialty material research, folks working with this compound aren’t interested in generic fillers. They want a reagent that withstands scrutiny from research notebooks, in-house audits, and regulatory submissions. With its known configuration and reliably tested purity, 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole avoids the disappointment of inconsistent lots, which means teams can produce batches with confidence and accuracy.

    Researchers see value in the subtle details. For those in drug discovery, this pyrazole derivative’s substituents help block metabolic soft spots that often ruin the bioavailability of fragile leads. Instead of crossing fingers and hoping for stable candidates, teams leverage its chemical backbone as a foundation for real medicinal chemistry. In the crop science sector, the unique mix of electron-withdrawing groups and amino-thiol functionality allows tailored reactivity when designing novel fungicides or herbicides—where selective activity is not a luxury, but a requirement.

    Experience Speaks Louder Than Jargon

    Having spent hours in labs where minor impurities derail weeks of effort, I know how much rides on the reliability of key building blocks. There’s nothing more frustrating than tracing a failed reaction back to a batch of starting material that didn’t meet spec. The compounds that survive my repeat purchases—and the ones that make their way into shared protocols—are the ones with documented, lab-verified track records. With this pyrazole derivative, manufacturers win trust not with brochure copy, but by delivering consistent analytical results, supported by chromatography data and spectra that match published standards.

    Looking across product lines, there’s a clear rift between generic, commodity-grade pyrazoles and the kind backed by reliable sourcing, impurity profiling, and transparency around synthesis origins. This isn’t a self-cleaning oven; it’s a compound that rides on its reputation in the hands of actual users. Those who care about lot-to-lot consistency, whether for regulatory filings or scaling to pilot plant, stick with variants where quality control means something more than a checkbox.

    Specification, Handling, and the Details That Matter

    Specification sheets tell a partial story. Bench scientists look beyond melting point and solubility; they pay attention to impurity profiles and by-product signatures that can show up unexpectedly during synthesis. This particular pyrazole comes in as a white to slight off-white crystalline solid, often packaged under inert atmosphere to avoid unwanted oxidation or moisture uptake. Typical purity specs reach over 98% by HPLC, a threshold most demanding chemists appreciate. Trace metal contamination, if present, is quantified and remains below the established limits for pharmaceutical intermediate work.

    The difference from similar products often traces back to how suppliers handle post-synthesis purification. With this compound, extra effort goes to removing closely related side products, something that downstream users notice immediately in improved reaction yields and less trouble during purification. Not every vendor delivers at this level, and the gap shows in both yield and operational headaches. In addition, handling protocols matter on the bench. Packaged and shipped in amber bottles or light-blocking containers, the compound demonstrates stability—an advantage for storage and transport where high humidity or temperature swings pose a risk.

    Versatility in Application—With Real-World Payoff

    Many compounds claim versatility, but few prove their worth in side-by-side project comparisons. This pyrazole derivative finds its most frequent use as a core building block in synthesizing biologically active heterocycles. Peptide and small molecule chemists often turn to the amino group for selective functionalization, while the thiol group opens up targeted coupling opportunities—think of it as a toolkit for inventing new molecules with precision.

    In agrochemical discovery, structure-activity relationships hinge on small changes. Modifying the phenyl ring with dichloro and trifluoromethyl groups pushes activity profiles into regions that simpler analogs just can’t match. Compound libraries that incorporate this scaffold benefit not only from new activity, but improved resistance to metabolic breakdown, boosting both field performance and product safety. The ability to control and exploit these features takes center stage once projects reach late-stage development and registration, when regulatory agencies put each structure under the microscope.

    Real Users Drive Real Change

    Product stories aren’t built on sales pitches. They’re woven from lab notes, troubleshooting sessions, and team meetings where a failed experiment sends everyone back to square one. The research world, my own work included, favors those who adapt quickly, learn from setbacks, and ultimately choose tools that work without drama. This pyrazole lives up to those expectations not because of hearsay, but because published data and peer experience agree. Journal articles and patent filings cite it not as a rare specialty, but as a dependable workhorse for key transformations. Teams engaged in route scouting or lead optimization use its reactivity for forging challenging bonds—like C–N or C–S linkages—not out of habit, but out of longstanding trust in the compound’s performance.

    Plenty of debate circulates around the real vs. perceived value of designer reagents. With budgets scrutinized and project milestones measured down to weeks or days, the cost of re-running a multi-step synthesis due to poor starting materials outweighs any savings from cut-rate suppliers. In my own experience, the gamble on untested sources leads to delays, ruined samples, and hours spent unraveling batch discrepancies with QC. The unique standing of this compound doesn’t come from flash, but from a straightforward promise: what you see is what you get, every shipment.

    Comparing Against the Broader Chemical Landscape

    Every chemist has choices—thousands of alternatives exist in the pyrazole family alone. Many lack the complex electron character created by dichloro and trifluoromethyl substitution. Fewer offer both an unprotected amino and mercapto pair, presenting a much narrower landscape of possible coupling or conjugation strategies. These missing features often leave researchers boxed in, forcing them into extra protection, deprotection, or functional group interconversion steps that chew up time and resources.

    Other pyrazole derivatives target mainstream applications, like flavor and fragrance intermediates or low-toxicity dyes, but fall short in tackling demanding pharmaceutical or crop-protection tasks. Generic versions with higher impurity loads or loosely controlled synthesis conditions can introduce unknowns that derail entire project lines. In regulated industries, this isn’t simply inconvenient—it’s a deal breaker. Regulatory filings demand batch history, traceability, and supporting documents. Having a supplier or product incapable of meeting these standards costs more than just money; it throws roadblocks into product launch timelines and can even result in scrapped development programs.

    Addressing Common Hurdles—With Solutions Born of Practice

    It’s never enough to just point at a problem. Whether navigating scale-up headaches, chasing mystery impurities, or dealing with inconsistent reactivity, chemists expect solutions grounded in hands-on experience. For me and my colleagues, the resolution often involves returning to trusted suppliers, reviewing detailed chromatographic data, and pushing for full transparency in production methods. Reliable batches of 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole come backed with NMR, HPLC, and MS spectra so users don’t cross their fingers—they check, confirm, and move forward.

    For those scaling from bench to pilot plant, a steady supply chain trumps last-minute cost cutting. Coordinated logistics with temperature control, real-time tracking, and regular documentation updates help bridge the gap between clever bench science and industrial reliability. Solutions don’t stop at delivery—they cover after-sales troubleshooting, rapid feedback in case of unexpected results, and responsive technical support based on genuine field experience.

    Building on E-E-A-T: Expertise, Experience, Authority, and Trustworthiness

    The importance of proven experience and transparency stands out in every procurement decision. No one wants an untested variable becoming the bottleneck on a high-stakes deadline. From my own journey—early-career researcher to project team leader—I’ve learned the hard way that authoritativeness grows from repeatable results and a commitment to open communication. Behind this product stands a network of reference standards, published research, and peer validation. Trust comes from batch documentation, regular analytical verification, and proactive updates about specification changes.

    Solutions That Move Science Ahead

    Modern research isn’t a solo effort; it thrives on partnerships between bench scientists, process engineers, procurement teams, and knowledgeable suppliers. Problems get solved when all these players share data, challenge assumptions, and circle back when new hurdles show up. That’s why a product like 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole holds more than a line in a catalog. It marks a checkpoint where performance, reliability, and real-world support matter more than price or packaging.

    Working through tough projects and scale-ups, the role of careful documentation and proven chemical standards only becomes more important. With a foundation built on published data and direct feedback from research teams, this compound keeps real science moving forward—uninterrupted by the surprises that too often come from cutting corners. In a field where outcomes impact both patient health and global food security, there’s no room for guesswork or compromise.

    Growing the Next Chapter

    Fresh ideas and new applications will keep changing where and how this compound works. Young researchers might discover novel uses—maybe in material science or advanced polymer synthesis—as their toolkits and imaginations expand. Collaboration fuels these breakthroughs. Shared methods, open-access papers, and international standards all shape how specialty chemicals enter the workflows of tomorrow’s discovery teams.

    From the smallest biotech startup to the biggest agrochemical multinationals, the lessons are the same. Set high expectations for purity, consistency, and transparency. Demand batch data and verification, and keep communication lines open between those who make the compounds and those who build tomorrow’s breakthroughs with them. That mindset transforms a specialty molecule into a catalyst for innovation, no matter where the science leads next.

    Practical Steps For Those Stepping Into This Field

    Anyone looking to incorporate advanced pyrazole derivatives could start by reviewing the literature—not just to confirm synthetic procedures, but to see how teams in similar industries overcame roadblocks using the compound. Reach out to suppliers for analytical data packages. Insist on clarity about storage, shipping conditions, and shelf life, especially if operations run across humid or high-temperature zones. Build a track record of verified performance in your own lab before scaling up. Consider batch blending or early-stage robustness testing to gauge how the compound behaves across slightly different conditions, especially under pressure to deliver on tight deadlines.

    The best performing teams I’ve worked with follow a simple formula: set clear quality standards, hold suppliers accountable, and document everything that matters in the workflow. This culture shields against surprises and builds confidence when launching new projects or responding to regulatory reviews. That mindset, built from hands-on practice and open sharing of knowledge, turns specialty chemicals from risky unknowns into reliable assets.

    Onward, Delivering Results That Last

    The landscape of specialty fine chemicals keeps changing, with regulatory scrutiny going deeper and applications evolving faster than ever. A compound like 5-Amino-3-Mercapto-1-(2,6-Dichloro-4-Trifluoromethylphenyl)Pyrazole doesn’t hold its position because of steady marketing, but on a steady record of trust, experience, and shared success. Its unique combination of chemical stability, reactivity, and supporting literature sets the benchmark in advanced syntheses—from targeted pharma to next-gen agroscience. As the story of scientific progress unfolds, those who keep a keen eye on experience, evidence, and accountability will continue to move research forward—transforming potential into real outcomes, one batch at a time.