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4-biphenylyl

    • Product Name 4-biphenylyl
    • Alias biphenyl-4-yl
    • Einecs 202-051-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    887261

    name 4-Biphenylyl
    molecular_formula C12H9
    molar_mass 153.20 g/mol
    appearance White to pale yellow crystalline solid
    melting_point 68-70 °C
    boiling_point 276-278 °C
    density 1.0 g/cm³
    solubility_in_water Insoluble
    structure_type Aromatic hydrocarbon
    CAS_number 92-52-4

    As an accredited 4-biphenylyl factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 4-biphenylyl chemical is packaged in a 25-gram amber glass bottle with a secure screw cap and tamper-evident seal.
    Shipping **Shipping Description for 4-Biphenylyl:** 4-Biphenylyl is shipped in tightly sealed containers, protected from light and moisture. The chemical should be labeled appropriately and transported according to standard regulations for organic solids. Ensure packaging prevents leaks or spills; handle with care to avoid damage during transit. Follow all local, national, and international shipping guidelines.
    Storage 4-Biphenylyl (4-phenylphenyl) should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Protect it from moisture and direct sunlight. Ensure proper labeling, and store at room temperature. Follow all relevant safety guidelines and local regulations for storage of organic chemicals.
    Application of 4-biphenylyl

    Applications of 4-biphenylyl in Industrial Manufacturing

    We produce 4-biphenylyl to meet rigorous industrial quality requirements for advanced manufacturing sectors. The unique chemical properties of 4-biphenylyl support high-value processes in areas from liquid crystal synthesis to high-performance polymer modification. The following sections outline specific application fields, with manufacturing details, usage guidance, and compliance information for B2B customers seeking secure supply and technical consistency.

    1. Liquid Crystal Intermediate for Display Technologies

    4-biphenylyl serves as a foundational intermediate in the synthesis of high-purity liquid crystals used in screen panels and optoelectronics. Manufacturers integrate the compound into multi-step organic syntheses forming core mesogenic structures for nematic and smectic phase displays. Stringent raw material specifications reduce ionic contamination potential and support precise color and electrical response requirements in electronic displays. Final production steps emphasize maintaining lot-to-lot consistency and traceability throughout upstream and downstream processing.

    Industry compliance standards

    • IEC 61290-1-1: Liquid crystal materials for electro-optical devices
    • RoHS Directive 2011/65/EU – Restriction of hazardous substances in electrical and electronic equipment
    • ISO 9001:2015 – Quality management system for chemical production
    • EU REACH Regulation (EC) No 1907/2006 for pre-registration and registration

    Typical usage ratio

    • 10–40% by weight as a core building block in custom mesogenic mixtures
    • Ratio adjusted based on optical birefringence and thermal stability requirements

    Downstream process integration

    • Introduced during initial organic synthesis for mesogen core units
    • Reacted with alkylating and esterifying agents in controlled solvent environments
    • Purification follows via recrystallization or column chromatography prior to blend formulation

    Final product types

    • Liquid crystal mixtures for TFT-LCD panels
    • OLED module liquid crystal layers
    • Electronic paper display fluids
    • Specialty optical films for smart glass technologies

    2. High-Performance Polymer Modification

    Chemical producers adopt 4-biphenylyl as a comonomer or end-functional modifier in specialty polymers, notably in the production of thermotropic liquid crystal polymers (LCPs) and high glass transition temperature engineering resins. This aromatic backbone improves rigidity, flame-resistance, and mechanical retention. Integration protocols focus on precise monomer ratios and real-time process monitoring to ensure targeted polymer chain architecture and molecular weight consistency for technical plastics used in automotive and electronics.

    Industry compliance standards

    • UL 94 – Flammability standards for plastic materials
    • ISO 1043-1:2011 – Abbreviations for plastics and identification principles
    • IATF 16949:2016 – Automotive quality management
    • RoHS and REACH directives for polymer raw materials

    Typical usage ratio

    • 2–12% molar incorporation into copolymer chains, adapted for melt viscosity and mechanical property requirements

    Downstream process integration

    • Introduced into continuous polymerization reactors after pre-drying
    • Copolymerized with other aromatic monomers under inert gas conditions
    • Blended in pelletizing or extrusion stages for modified engineering resins

    Final product types

    • Thermotropic liquid crystal polymer granules and films
    • High-temperature electronic connector housings
    • Engine compartment automotive fasteners
    • Precision injection-molded parts for medical devices

    3. Pharmaceutical Intermediate in Antihistamine Synthesis

    Pharmaceutical synthesis employs 4-biphenylyl as an essential intermediate in the production of second-generation antihistamines, including cetirizine-structured APIs. The aromatic system allows for controlled transition to target functional groups by established Friedel–Crafts alkylation and amination steps. Manufacturers control parameters such as reagent stoichiometry and impurity profile to meet compendial specifications and batch validation under cGMP environments.

    Industry compliance standards

    • ICH Q7 – Good Manufacturing Practice for APIs
    • US FDA 21 CFR Part 211 – cGMP for finished pharmaceuticals
    • Ph. Eur., USP, JP pharmacopeias as required by final product registration
    • ICH Q3A/B – Impurities in new active substances and drug products

    Typical usage ratio

    • Stoichiometric conversion; generally 1 mol equivalent for targeted intermediate synthesis
    • Adjusted for process yield and downstream API purity targets

    Downstream process integration

    • Reacted with chloroalkylating agents in solvent-controlled batch reactions
    • Purification by extraction and crystallization prior to amination
    • Integrated into validated multi-step API synthesis pathway

    Final product types

    • Active pharmaceutical ingredients for oral antihistamines
    • Key intermediates for non-sedating allergy treatments
    • Reference compounds for generic pharmaceutical synthesis
    • Final bulk drugs after further processing

    4. Dye and Pigment Precursor for Colorant Manufacturing

    In the dye industry, formulators utilize 4-biphenylyl as a precursor for synthesizing high-purity organic pigments, particularly for producing anthraquinone and azobenzene structures. Its stable aromatic core promotes brightness and lightfastness in end-use textiles and coatings. Process control emphasizes reaction completeness and color index reproducibility, essential for industrial colorant houses supplying automotive, architectural, and textile sectors. Downstream, stringent batch testing supports customer certification protocols for light stability and toxicity.

    Industry compliance standards

    • GHS-CLP (EU Regulation 1272/2008) for labeling and safety documentation
    • ISO 105-A02 – Color fastness to artificial light
    • OEKO-TEX® Standard 100 for textile safety and chemical residues
    • EN 71-3:2019 – Safety of toys – migration of substances for pigment applications

    Typical usage ratio

    • 5–20% by weight in pigment intermediate synthesis; ratio based on required shade strength and target molecular design

    Downstream process integration

    • Used in coupling or condensation reactions for pigment backbone assembly
    • Subjected to successive purification and milling stages
    • Final pigment dispersions adapted to specific solubility and particle size criteria

    Final product types

    • Organic pigments for automotive and industrial coatings
    • Printing inks for packaging and textiles
    • Color concentrates for high-performance plastics
    • Special effect dyes for high-end decorative applications
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    Certification & Compliance
    More Introduction

    4-Biphenylyl: Product Insights from a Chemical Manufacturer

    Introducing Our 4-Biphenylyl: Model, Specifications, and Real-World Use

    4-Biphenylyl, known in chemical circles as 4-Phenylbiphenyl or simply as a biphenyl derivative, has become an indispensable raw material across multiple industries. In our production facility, we synthesize 4-biphenylyl through careful processes involving controlled Suzuki coupling reactions. Purity, particle distribution, and moisture content undergo constant monitoring—not out of routine, but from direct experience in fielding differences that affect downstream performance.

    The white crystalline powder of our standard model, referenced in production as 4-BP-2024, consistently registers at a purity of over 99.5% by HPLC. Residual solvents remain below industry standard detection limits, reflecting real diligence throughout our purification processes. Melting point remains sharp—between 165 and 167°C—attesting to our controls against co-crystallization and process contamination. Particle sizing, evaluated by laser diffraction, supports ease of handling both for bulk polymerizations and custom synthesis requests.

    The Difference Starts at Raw Material Selection

    Batches start with verified aromatic sources and catalysts from vetted global suppliers. Each incoming drum gets tested not only by certificates, but by hands-on inspection and spectral checks. Everything from storage humidity to packaging protocol receives consideration, since we learned early that biphenyls are sensitive to atmospheric moisture and even trace oxidants. Many first-time formulators underestimate purity's impact on yield or color bodies produced when scaling up, so we’ve set the bar higher than regulatory minimums.

    How Processing Impacts Finished Product Quality

    From experience working with both start-ups and legacy firms, we’ve seen how inconsistencies in 4-biphenylyl can halt a batch or lead to off-spec features in polymers and advanced materials. Some suppliers skimp on repeated recrystallization, causing lower clarity and more stubborn particulate fragments. That’s why every lot receives full QC profiling, including FTIR and GC-MS characterization, so unexpected signals or impurities never surprise anyone downstream.

    Competing products on the market often show yellowish overtones or faint odor due to incomplete washing and solvent residue. Those details matter in liquid crystal displays and high-grade intermediates. For clients synthesizing OLED materials, we protect every batch from light and oxygen exposure. It is not just a technical formality—cut corners at any step reflect clearly in device lifetimes or response rates, which we witnessed in clients’ own comparative test runs.

    Supporting Applications with Proven Process Consistency

    Our 4-biphenylyl finds a home in high-demand areas—organic synthesis, photoconductive polymers, specialty coatings, and electronic displays. For many, the compound serves as an intermediate for pharmaceuticals or agrochemicals. In these sectors, a single point deviation—for example, a rise in isomeric impurities—can ruin an entire product cycle or introduce unwanted biological response.

    We monitor batch-to-batch consistency through spectral fingerprints. Chemists who depend on reproducibility have sent feedback, noting no measurable drift in spectral peaks or high-volatility components over multi-year supply programs. Even our larger industrial users, with annual draws reaching metric tons, have pointed out less fouling in reactors thanks to our product’s lower trace metal and residue burden.

    Meeting Tight Industry Standards: Beyond the Basics

    In the world of specialty chemicals, hitting 99% purity does not always suffice. We push further, aiming to minimize all assay variables. We remember one polymer manufacturer who found a 0.5% unknown peak caused pigmentation issues—something our own internal screens had flagged, saving that client costly reformulation. Afterward, both our teams collaborated to dial in the right level of crystallization—avoiding both dust fines and chunky aggregates that interfere with dosing in high-throughput reactors.

    Our internal protocols now include testing for trace halogens, sulfur, and nitrogen compounds—any of which can sabotage final performance. When a customer working in thin-film transistor production wanted ultra-low sodium content, for instance, we altered our purification and rinsing steps, resulting in a product certified at under 2 ppm—something few suppliers prioritize unless challenged by demanding end-users.

    Solubility and Handling: Real-Life Implications

    We’ve experimented with various solvents and blend conditions, uncovering ways to maximize dissolution rates. In the lab, 4-biphenylyl dissolves readily in THF, DCM, and hot toluene, but exact solubility curves shift based on all upstream particulars—factors often glossed over in technical papers or by traders reading off translated data sheets. Critical for engineers scaling up, our bespoke solubility reports draw on thousands of in-house tests, guiding users through safe and accurate solution preparations.

    Physical handling matters as well. While competitors sometimes ship loosely capped drums, risking moisture ingress, each drum leaving our facility is nitrogen-purged, double bagged, and heat-sealed. No one at the receiving dock gets stuck with a clumpy, partially hydrolyzed product. We’ve learned from experience—once a customer reported a sticky, bridged powder from an overseas broker, leading us to redesign our anti-static and humidity-control packaging lines.

    What Sets Our 4-Biphenylyl Apart

    We believe difference comes from embedded learning. We’re not just selling a specification—we are contributing to customer workflows at each step. Through long collaborations, we have built up a history of solving problems typical of high-end materials synthesis. Examples include providing micro-lot customizations for research organizations, keeping oddball solvents and impurity profiles to precise customer specs, and doing so on a timescale that matches real project timelines.

    A frequent misconception out there is that all 4-biphenylyl is the same, no matter the producer. Yet industrial processes are sensitive. Stable phase changes, shelf life, and compatibility with downstream coupling reactions depend on more than just hitting a generic purity target. Long-chain aromatics act as contaminant sponges if mishandled, something our own analytical team first observed in cross-comparisons. Our extra steps—from solvent recovery to static neutralization—contribute directly to fewer processing shut-downs for clients.

    Working Directly from the Source: Manufacturer Advantages

    Dealing with us as the actual producer removes unknown links from your supply chain. Direct feedback shapes continual improvement. Last year, a major OLED developer needed their 4-biphenylyl packaged in small argon-flushed ampules for glovebox use. Instead of negotiating through middlemen, our technical manager worked with their R&D chemists—delivering several pilot runs, which ultimately led to a change in their production line SOP.

    With full traceability, we provide every customer with comprehensive documentation on all intermediary stock. A policy of sample retention for 36 months has sped up problem-solving numerous times—a lesson reinforced by a case where a legacy client traced an unexplained odor back to a third-party logistics warehouse, not our product or sealed packaging. By keeping sample vials longer than the legal minimum, we were able to defend our own processes and help that customer identify the real source.

    Real-World Impact: Minimizing Downtime and Waste

    4-Biphenylyl appears as a technical line-item in thousands of recipes, but our data and partnerships have shown it can cause or prevent significant production hiccups. During audits, we’ve spotted how subtle variations in the product—unnoticed in standard analytics—could cause gumming or cross-linking in client systems. Shared test data with clients have led to optimized holding and feed practices, cutting waste rates by 5-10% depending on the polymer system.

    Our role as a manufacturer is to invest in raw material quality at the level most others overlook. Process engineers routinely ask for batch-specific feedback on reactivity in custom coupling agents or color-forming intermediates. We don’t ship product based solely on generic standards. Each lot intended for electronics goes through stricter heavy-metal elimination and light-exposure certification, reflecting end-user requirements we’ve developed hand-in-hand with the sector’s most experienced chemists.

    Safety, Environment, and Community Engagement

    The world demands more than technical performance today. Running a chemical works in the 21st century means taking environmental stewardship seriously. While 4-biphenylyl is not considered acutely toxic, we have invested in fully enclosed reactor lines, VOC-capture circuitries, and solvent recycling right on site. Regular audits—conducted both internally and by multinational partners—keep our teams sharp on compliance and emerging environmental guidelines. We engage routinely with neighboring communities, offering plant tours and information sessions to demystify what goes on behind our gates.

    Waste minimization is built into our processes from the ground up. By recovering and reprocessing solvents, we lower our environmental footprint while keeping costs stable even in turbulent world markets. Partnering with certified handlers for any unavoidable residues, we confirm safe treatment and documentation at every stage.

    Continuous Improvement & Collaboration

    We foster an R&D-driven approach—open to innovation but always grounded in what works. Long-time collaboration with universities and specialty material laboratories produces new handling protocols, jointly published in both trade journals and supply chain discussion groups. Our internal development group regularly tests next-generation purification columns and solid-phase extraction units, aiming for trace contaminant control levels that anticipate next decade’s demands.

    Feedback from researchers and production chemists informs future product variants. If a customer develops a process-grade film needing lower residual aromatic tars, our technical group works side-by-side with theirs, sometimes creating a new “sub-grade” specification in response. Adaptation happens quickly; we maintain pilot-scale reactors on-site ready to trial novel purification strategies or adjustments for unique project needs.

    Supporting Customer Success: From Formulation to Full-Scale Production

    We share troubleshooting insights, seeing every client’s challenge as an opportunity to enhance knowledge both for them and ourselves. One organic semiconductor manufacturer gained significant yield improvement after switching to our solvent-tailored grade of 4-biphenylyl. The switch eliminated filter blockages and enabled longer reactor uptime between maintenance cycles, an advantage leading to measurable cost savings. We didn’t stop at supply; plant visits and joint process audits helped confirm root causes, leading to further optimization.

    Outcomes matter as much as initial specs. Some polymer engineers we work with have remarked after process review how trace byproducts previously overlooked could have caused compounding delays. Tackling these issues at the source reduces the need for downstream corrective action or costly secondary purification.

    Reliability Gained Through Experience

    Every kilogram leaving our facility benefits from cumulative learning. Our production team keeps live logs tracing every stage, sharing findings with clients on request. Whether supporting small-scale advanced material start-ups or global electronics groups, reliability is not a buzzword but a fundamental goal. The team has lived through resin fouling nightmares, unplanned shutdowns due to inconsistent intermediates, and knows the peace of mind that comes when every drum labeled 4-biphenylyl works exactly as intended.

    A major difference between a manufacturer and a reseller or broker is the depth of insight available. If an unforeseen challenge arises, our technical team works from first principles, calling on deep process records and first-hand knowledge. We see ourselves as partners in our clients’ innovation journey, motivated by the success stories behind every shipment.

    Conclusion: The Value of Choosing a Committed Manufacturer

    The story of 4-biphenylyl at our plant is the story of dedication, adaptability, and a determination to stand behind the product with more than a data sheet. We harness the science and craft of chemical manufacturing every day, building in the processes and diligence our industry’s future relies on. For any team taking on challenging new chemistries or pushing established processes to new limits, the right starting material can make all the difference. We take pride that, for so many, our 4-biphenylyl provides that reliable foundation.