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HS Code |
151619 |
| Chemical Name | 2-Cyanophenol |
| Synonyms | o-Cyanophenol |
| Molecular Formula | C7H5NO |
| Molar Mass | 119.12 g/mol |
| Cas Number | 611-20-1 |
| Appearance | White to pale yellow solid |
| Melting Point | 66-69°C |
| Boiling Point | 275°C |
| Density | 1.18 g/cm³ |
| Solubility In Water | Slightly soluble |
| Pubchem Cid | 12145 |
| Structure | Benzene ring with ortho cyano and hydroxyl groups |
| Smiles | C1=CC=C(C(=C1)O)C#N |
| Inchi | InChI=1S/C7H5NO/c8-5-6-3-1-2-4-7(6)9/h1-4,9H |
As an accredited 2-Cyanophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 2-Cyanophenol is packaged in a 100-gram amber glass bottle with a secure screw cap and safety labeling for laboratory use. |
| Shipping | 2-Cyanophenol should be shipped in tightly sealed containers, protected from light and moisture. It must be handled as a hazardous material, following local and international transport regulations. Suitable secondary containment should be used, and appropriate hazard labels must be attached. Ensure compliance with UN 2811 (Toxic Solid, Organic, N.O.S.) guidelines. |
| Storage | 2-Cyanophenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Protect from moisture and incompatible substances such as strong oxidizers and bases. Store in a designated chemical storage cabinet, and ensure containers are clearly labeled to prevent accidental misuse. |
Applications of 2-Cyanophenol in Industrial Manufacturing2-Cyanophenol acts as a crucial intermediate in several chemical manufacturing industries. We produce this material for consistent industrial supply, focused on strict compliance, precise formulation, and downstream compatibility. The following sections outline major commercial routes where 2-Cyanophenol forms an integral part of well-established value chains. 1. Synthesis of Pharmaceutical IntermediatesPharmaceutical manufacturers utilize 2-Cyanophenol as a key intermediate for the synthesis of active ingredients, especially in production of aromatic amine and heterocyclic drug building blocks. In this context, the compound enters amidation, reduction, and cyclization processes critical for APIs such as various anti-inflammatory and CNS-active molecules. QC teams monitor impurity profiles rigorously according to multi-pharmacopoeia standards, and batch records must document every charge and intermediate lot. Integration typically occurs in the initial condensation or ring-formation stage following purification. Industry compliance standards
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2. Agrochemical Technical IntermediateProducers of crop protection chemicals deploy 2-Cyanophenol as a technical intermediate in the synthesis of specific herbicides and fungicides containing phenolic and nitrile structures. This material participates in coupling and substitution reactions during pre-formulation of active ingredients, and downstream processes require detailed tracking of cyanide and phenol residues. Proper hazard management and environmental release controls are essential as per crop chemical regulations. Material typically enters the process after an initial weighing and solvent dissolution stage, ensuring complete consumption in the main synthetic transformation. Industry compliance standards
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3. Dye and Pigment IntermediateIn the specialty colorant sector, 2-Cyanophenol contributes to the synthesis of certain azo and anthraquinone dye intermediates, particularly for textile and plastic coloration. Chemical manufacturers require high-purity lots and controlled moisture. Its hydroxyl and nitrile groups facilitate diazotization and coupling reactions, leading to advanced chromophores. Addition occurs in batch reactors under temperature control to ensure even functionalization and high conversion to target dye molecules while avoiding over-reduction or side product formation. Industry compliance standards
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4. Production of Electronic Grade ChemicalsManufacturers of electronic and semiconductor chemicals incorporate 2-Cyanophenol in the preparation of high-purity intermediates essential for photoresists and image-forming compounds. The aromatic structure serves as a precursor in crafting custom monomers with controlled functionalization. Stringent quality systems demand trace-level impurity monitoring, and the material undergoes extensive purification before use. Integration occurs in closed-system microreactors, meeting the critical requirements for particle and metal contamination controls. Industry compliance standards
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5. Fine Chemical Building Block for Specialty PolymersProducers of advanced engineering plastics and specialty polymers leverage 2-Cyanophenol for its phenolic and nitrile functions, supporting controlled polymer architecture. The material is often involved in either the initiation or modification phases during the preparation of resins with heat-resistant and flame-retardant characteristics. Polymer process engineers fine-tune addition ratios to achieve target molecular weights and functional group balance, with integration at the prepolymer formation stage within inert-atmosphere vessels. Industry compliance standards
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Every chemical tells a story. In the case of 2-cyanophenol, a white to light-beige crystalline compound, the story starts with its clean aromatic core and a nitrile group at the ortho position—a combination that sets it apart from the crowd of standard aromatic intermediates. In our labs, we call it by its model: 2-Hydroxybenzonitrile, but most know it as 2-cyanophenol. You will spot its C7H5NO structure in technical literature. If you ask why a chemical manufacturer invests in its production, it’s because this molecule delivers value in ways less obvious on paper.
Our experience with 2-cyanophenol began over a decade ago in response to growing requests from pharmaceutical and agricultural clients. We adapted our process to favor high purity, low isomer impurity, and minimal moisture content, critical factors many overlook. Standard technical grade often hits purities around 98%, but the demands of custom synthesis sometimes push us beyond 99% when warranted by stringent client protocols.
We source raw materials with assurance about origin and traceability. Our synthesis routes avoid less stable byproduct formation, letting us deliver reproducibility that bench chemists and pilot-scale engineers appreciate. Rather than outsourcing these steps, we handle every phase internally to maintain process control.
If you compare 2-cyanophenol to more widely traded nitrile aromatics, the difference comes down to both its activity and reactivity. The classic p-cyanophenol, for example, separates its functional groups across the benzene ring, limiting certain ortho effects. Our customers in medicinal chemistry focus on the ortho positioning because it creates unique possibilities for further transformations. The adjacent nitrile and hydroxyl enable selectivity in reactions where meta- or para-isomers fall short.
Resorcinol, salicylic acid, and even benzonitrile might turn up in the same conversation. You won't find the same bifunctionality. The ortho structure in 2-cyanophenol unlocks chelating abilities useful for metal complex formation and provides starting points for constructing more elaborate heterocycles. New agrochemicals, dyes, and active pharmaceutical ingredients call for this flexibility.
Scaling up 2-cyanophenol isn’t just about running the chemistry. Our reactors negotiate elevated temperatures while ensuring that the nitrile group stays intact. Moisture control in the production area is a constant concern because the hydroxyl and nitrile react with atmospheric water over time, risking the slow formation of unwanted byproducts. We invest heavily in environmental monitoring, keeping storage areas cool, dry, and shielded from sunlight—a strategy that pays off when customers notice their product arrives free from unknown impurities.
Every batch gets checked not only for chemical purity but also for shelf-life stability—something many first-time buyers overlook until product failures downstream. We’ve learned to balance throughput and quality by continuously updating our crystallization and purification equipment. Each day on the line, our technicians adjust for slight raw material differences and chart detailed batch histories.
With changing global regulations and customer expectations, we trace each production lot from raw material arrival to final packaging. Not every 2-cyanophenol supplier can point to a full electronic batch record, but regulatory audits and customer visits have made this approach essential. Our compliance team reviews every certificate, including those confirming the absence of specified impurities like heavy metals and polyaromatic hydrocarbons.
Over the years, several clients approached us after frustrating surprises with off-shore shipments. They reported mislabeling and lots that included unreacted precursors or isomeric impurities that complicated their downstream purification. Our internal documentation, focus on transparency, and regular third-party audits have kept these mistakes off our shipping docks. We see this as a mark of professionalism and a commitment to the long game.
Growing awareness around chemical waste management and emissions has impacted how we produce and package 2-cyanophenol. Discharge minimization isn’t only about legal compliance; it’s also about resource conservation. Our wastewater pre-treatment tackles residual cyanide and phenolic compounds before release, protecting both the environment and worker safety.
Packaging materials, too, see careful selection. We replace single-use plastics and prioritize recyclable containers, particularly for our large-volume customers. Over the past three years, efficiency improvements have reduced our per-kilogram energy consumption for this product by over 20%. Such investments cost time and capital, but they shield us from regulatory shocks and reduce future liabilities.
Pharmaceutical and agrochemical synthesis headline our order books, with 2-cyanophenol serving as a critical starting point in creating benzoxazoles, benzothiazoles, and other fused-ring compounds. We ship to research houses formulating new herbicides, and our experience tells us that small- to medium-scale users measure quality by solubility and crystal habit. Our crystalline material dissolves predictably in ethanol, acetone, and common organic solvents, letting users scale lab reactions with minimal reoptimization.
Academic collaborations bring new excitement. We support Masters and PhD research with smaller, yet still high-quality, quantities. Students often approach us with questions about reactivity, toxicity, or storage—and our technical team responds with firsthand experience, not canned answers. Customers probing isotopic substitution or custom labeling projects appreciate that we can adjust protocols and mother liquor conditions to support more unusual requests.
Beyond traditional synthesis, the pigment and dye industries find value in 2-cyanophenol’s reactivity. Our partners in colorant manufacturing use it as a key intermediate, modifying its structure to yield shades and fastness properties unattainable from alternatives. Here, batch consistency keeps downstream color profiles predictable, leading to fewer wasteful reruns.
One lesson we’ve learned: purity isn’t just a number. Impurities can catalyze unwanted side reactions or poison expensive catalysts in hydrogenation and cross-coupling. We fine-tune crystal size for those who demand rapid dissolution or specific surface area, especially for automated dispensing lines. It’s impossible to overstate the impact of reliable sieving and drying—sloppy handling turns a high-purity intermediate into a stubborn bottleneck.
Some global producers offer only technical grade with limited controls on metal content or solvent residues. We serve customers with both standard technical product and higher-purity pharmaceutical grade, shipped in tamper-evident containers. Experience tells us that labeling and documentation—clear, concise, and accurate—matter as much as product appearance. Missing or delayed paperwork causes headaches, so we deliver with every package, every time.
From day one, our teams undergo real-world training on safe handling. 2-cyanophenol carries hazards typical of aromatic nitriles and phenols. We enforce best practices for personal protective equipment, local ventilation, and spill management. During customer audits, we’re often asked about worker protection measures, right down to storage signage and secondary containment. Our investment in ongoing safety education isn’t just a matter of compliance; it comes from watching incidents in less careful plants derail entire operations.
We also work closely with downstream users to ensure safe and compliant storage and disposal. Many first-time users underestimate the sensitivity of 2-cyanophenol to moisture and light, leading to batch failures and unpleasant surprises. By sharing our own lessons—drawn from years moving material between labs, warehouses, and production—we’ve helped customers avoid common missteps.
Shipping specialty chemicals takes organization and predictability. Customs clerks focus on documentation—no two shipments flow through without a proper material safety data sheet and full lot traceability. We have watched large, generic chemical traders stumble on these hurdles. For 2-cyanophenol, the key is packaging that prevents both breakage and moisture ingress. Our favored option remains high-density polyethylene-lined steel drums, which survive both sea and overland journeys.
Temperature control through the supply chain ensures product arrives within specification. We learned to pre-cool outgoing loads during summer months as unforgiving heat increases risk of degradation. These steps add cost and time but cut costly rejections and returns almost to zero.
Technical specialists who visit our facility point out the versatility 2-cyanophenol brings to new-molecule discovery. Our experience with custom derivatization projects supports development of a wide range of heterocyclic scaffolds, fueling medical chemistry research around the world. As new routes for creating advanced polymers and materials emerge, the ortho-functional design opens unexplored regions of chemical space.
In research, applications evolve fast. Teams working in sustainable syntheses experiment with green oxidation and reduction conditions, relying on us to provide not just the raw material but insight about byproduct formation and downstream processing. Over time, collaborative feedback has driven improvements in our own quality controls, introducing new metrics to monitor trace impurities and batch variability.
Trust develops slowly. Decades spent refining production, handling, and shipping practices leave a mark. Our real success shows up in long-term relationships rather than single shipments. Repeat orders come from customers who have seen the pitfalls of cheap, poorly controlled alternatives. Shortcuts in nitrile chemistry bring long-term headaches; a failed key intermediate means failed projects, missed milestones, and strained credibility.
Each order we dispatch represents both our expertise and our reputation. By listening to chemists—who work on tight deadlines and budgets—we continually adjust production schedules and technical support to meet unique requests, from alternative packaging sizes to expedited shipping. Regular conversations with in-house technical teams on the customer side keep us updated on evolving requirements, which helps us stay on target with every batch.
Regulatory frameworks grow tighter year after year, and chemical users expect transparency and responsiveness. We invest in lab infrastructure, instrument calibration, and third-party certifications with a clear goal—build confidence at every stage. Our product has found new roles in catalyst development, advanced material research, and as a base for combinatorial libraries.
Global supply chains have become more unpredictable, and reliable domestic sourcing for 2-cyanophenol now carries new weight. Those who have experienced delays or quality lapses with unregulated suppliers return to established producers with renewed appreciation for documented consistency. Through our investment in technical expertise, modern equipment, and customer support, our 2-cyanophenol continues to enable scientific progress while meeting the growing demands of compliance and sustainability.
