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Vitamin B6 Material Safety Data Sheet (MSDS)

Identification

Product Name: Vitamin B6
Chemical Name: Pyridoxine Hydrochloride
Synonyms: Pyridoxine, 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine hydrochloride
CAS Number: 58-56-0
EC Number: 200-386-2
Recommended Use: Food additive, dietary supplement, pharmaceutical ingredient
Supplier: Stated on product packaging
Contact Information: Refer to manufacturer or distributor label
Emergency Phone Number: Cited on safety label

Hazard Identification

Classification: Not classified as hazardous under GHS criteria
Physical Hazards: Not explosive, not flammable under standard conditions
Health Hazards: Low acute toxicity; may cause mild skin or eye irritation in sensitive individuals; ingestion of excessive amounts may affect peripheral nerves
Environmental Hazards: Expected to have low environmental impact under normal conditions
Pictogram: Not applicable; product often labeled without hazard symbol
Signal Word: None required
Hazard Statements: Not considered hazardous under OSHA Hazard Communication Standard
Precautionary Statements: Avoid prolonged exposure to dust; use good industrial hygiene practices

Composition / Information on Ingredients

Chemical: Pyridoxine Hydrochloride
Concentration: Typical preparations contain 98–100% active pyridoxine hydrochloride
Impurities: Trace water, residual solvents within permissible limits
Formulation: Fine, crystalline powder
Molecular Formula: C8H11NO3·HCl
Molecular Weight: 205.64 g/mol

First Aid Measures

General Advice: Move individual away from exposure; seek medical assistance if symptoms persist
Inhalation: Remove to fresh air; provide artificial respiration if breathing has stopped
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing
Eye Contact: Flush eyes with water for at least 15 minutes; seek medical attention if irritation develops
Ingestion: Rinse mouth with water; do not induce vomiting; call a physician if large quantities are swallowed

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: Strong water jets may disperse product powder
Specific Hazards: Product decomposes at elevated temperatures releasing nitrogen oxides, hydrogen chloride
Protective Equipment: Firefighters should use full protective gear and self-contained breathing apparatus
Special Procedures: Evacuate area; contain runoff from fire control or dilution for appropriate disposal

Accidental Release Measures

Personal Precautions: Wear dust mask or respirator; prevent contact with eyes and skin
Environmental Precautions: Prevent large spills from entering surface water, soil, or drainage systems
Cleanup Procedures: Sweep or vacuum spilled powder in a controlled manner; avoid creating airborne dust; place in marked, sealable container for disposal
Disposal: Manage as chemical waste; follow local environmental regulations

Handling and Storage

Handling: Use only with adequate ventilation; avoid creating or breathing dust; practice frequent hand washing and keep container tightly closed upon non-use
Storage: Store in cool, dry place away from direct light, heat, oxidizers; maintain original packaging or tightly sealed container; protect from moisture; store away from incompatible materials
Specific Practices: Designated area for laboratory or bulk handling; clearly labeled shelves; regular inspection for deterioration or contamination of stock

Exposure Controls and Personal Protection

Permissible Exposure Limit (PEL): Not officially assigned specific limits; good industrial hygiene dictates minimizing airborne concentrations
Engineering Controls: Use local exhaust ventilation or process enclosure to reduce dust formation
Respiratory Protection: Dust masks for routine handling; respirators for large spills or insufficient ventilation
Skin Protection: Lab coats, gloves resistant to powders, closed footwear
Eye Protection: Safety glasses with side-shields or goggles
Hygiene Measures: Avoid eating, drinking, or smoking in work areas; wash hands after use

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Odorless
pH: Neutral aqueous solution (5.5–7.0)
Melting Point: 205 °C (decomposes)
Solubility: Freely soluble in water (approx. 1 g/mL), slightly soluble in ethanol
Density: 1.35 g/cm³
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Not volatile
Flash Point: Not flammable
Partition Coefficient (log Kow): –1.5 (high water solubility)

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures in tightly closed container
Reactivity: Avoid strong oxidizers, acids, bases
Hazardous Decomposition Products: Nitrogen oxides, hydrochloric acid, carbon monoxide, carbon dioxide on combustion or thermal decomposition
Polymerization: Will not occur
Conditions to Avoid: Excessive heat, moisture, strong light

Toxicological Information

Acute Toxicity: Oral LD50 (rat): >5,000 mg/kg (low acute toxicity)
Chronic Effects: High chronic doses may cause sensory nerve damage, photosensitivity; such reactions seen in prolonged overdose situations
Skin and Eye Irritation: Mild, reversible irritation possible with direct contact
Inhalation Exposure: Possible respiratory irritation at high airborne concentrations
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen
Mutagenicity: Not mutagenic in standard assay
Reproductive Toxicity: No adverse effects at normal dietary supplement levels

Ecological Information

Aquatic Toxicity: Likely to have low toxicity to aquatic organisms; highly soluble in water; readily biodegradable
Persistence/Degradability: Rapidly biodegradable by environmental microorganisms
Bioaccumulation: Does not bioaccumulate based on high solubility and low log Kow
Mobility in Soil: High mobility due to high water solubility
Additional Information: Not expected to pose significant risk to plants or animals in typical concentrations encountered from normal use and disposal

Disposal Considerations

Waste Disposal Methods: Dispose of material according to local, regional, and national guidelines for non-hazardous organic chemicals
Contaminated Packaging: Rinse empty containers with water before usual disposal; recycle or incinerate if permitted
Special Considerations: Do not discharge concentrated product into drains, water courses, or onto soil

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not known as marine pollutant
Transport Precautions: Transport in sealed, labeled containers; protect against physical damage, heat, moisture

Regulatory Information

OSHA Status: Not considered hazardous under U.S. OSHA regulations
TSCA Inventory: Present
DSL/NDSL (Canada): Listed or exempt
REACH (EU): Registered and compliant
Label Requirements: Ensure product stays labeled with identity, safe handling, supplier contact details
Other Regulations: Not listed as controlled substance, not subject to specific safety or health restrictions apart from good laboratory and manufacturing practice