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Product Name: Vitamin B1
Chemical Name: Thiamine Hydrochloride
CAS Number: 67-03-8
Molecular Formula: C12H17ClN4OS · HCl
Relevant Uses: Nutritional supplement, food additive, pharmaceutical ingredient
Supplier Details: Manufacturer or distributor contact as per supply chain
Emergency Contact: Refer to local poison control center or supplier emergency number
Synonyms: Thiamine mono hydrochloride, Vitamin B1 hydrochloride
Classification: Not classified as hazardous according to GHS criteria under most normal conditions
Main Hazards: Dust may cause irritation to eyes, nose, or throat; ingestion may cause mild gastrointestinal discomfort
Label Elements: No pictogram required; precautionary statements are limited to handling dust
Other Information: Large exposure to dust could aggravate respiratory conditions; risk of allergic reaction is extremely low
Chemical Identity: Thiamine Monohydrochloride
Concentration: Typically 98% or greater by weight
Impurities: Possible trace hydrates, residual solvents, or excipients below 2%
Other Components: Usually none in pure standard; presence of added agents should appear in product-listed ingredients
Inhalation: Remove exposed person to fresh air; seek medical attention for ongoing discomfort
Skin Contact: Wash area thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse eyes gently with water for several minutes, remove contact lenses if present
Ingestion: Rinse mouth with water; give small volumes of water if conscious; seek medical advice for large amounts or symptoms persisting
Note to Physician: Product considered of low acute toxicity; treat symptomatically
Suitable Extinguishing Media: Dry chemical powder, CO2, water spray, or foam
Specific Hazards: Product can form combustible dust clouds; in fire conditions may emit toxic fumes such as nitrogen oxides, sulfur oxides, hydrochloric acid vapors
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Contain fire water runoff, avoid breathing combustion gases
Personal Precautions: Avoid dust generation; ventilation advised; use appropriate respirator if dust generated
Environmental Precautions: Prevent spillage into water systems; contain loosened product
Clean Up Methods: Sweep up material, place in a dry, clean, labeled container; wash area with water, avoid creating airborne dust
Disposal: Follow regulations for hazardous and non-hazardous waste
Handling: Minimize dust formation; handle with care; use with adequate ventilation; avoid direct contact with eyes or skin
Storage Conditions: Keep tightly closed in original container; store in a cool, dry, well-ventilated space; protect from light and moisture
Incompatible Materials: Strong oxidizers, acids, strong bases may degrade or interact with the product
Hygiene Practices: Wash hands after use, keep away from food, beverages, and animal feed
Occupational Exposure Limits: No official limits assigned; handle as a dust hazard with general hygiene standards
Engineering Controls: Local exhaust ventilation, general area ventilation recommended
Personal Protection Equipment: Safety goggles, laboratory coat, gloves made of nitrile or PVC; mask if handling bulk powder or cleaning up spills
Respiratory Protection: Dust mask or particulate respirator if airborne concentration exceeds comfort levels
Other Protective Measures: Use protective clothing to prevent skin contact, ensure eyewash facilities available
Appearance: White to yellowish crystalline powder
Odor: Slight characteristic odor, not pungent
Odor Threshold: Not determined
pH: 2.7–3.4 (5% solution)
Melting Point: 248–250°C (decomposes)
Boiling Point: Not applicable
Solubility: Freely soluble in water, practically insoluble in chloroform and ether
Density: 1.64 g/cm3 (approximate)
Partition Coefficient: Log P (octanol/water) ~ -2
Vapor Pressure: Not significant at ambient temperature
Other Data: Stable in dry form, forms hydrates in moist air
Chemical Stability: Stable under recommended storage conditions, especially in dry state
Potential Reactions: May react with strong oxidizers, acids, or alkalis leading to breakdown or color change
Hazardous Decomposition: Combustion generates nitrogen oxides, sulfur oxides, hydrochloric acid gas
Polymerization: Not known to occur
Conditions to Avoid: Moisture, heat, direct sunlight, incompatible chemicals
Acute Toxicity: Low oral toxicity, LD50 (rat, oral) estimated > 485 mg/kg
Potential Health Effects: Dust may irritate eyes, gastro-intestinal upset with large ingestion; chronic ingestion unlikely to produce harm under normal conditions
Skin and Eye Contact: Mild irritant
Sensitization: No evidence of skin sensitization
Carcinogenicity: Not listed as a carcinogen
Mutagenicity: No mutagenic effects observed in standard tests
Reproductive Toxicity: No known reproductive toxicity at nutritional doses
Aquatic Toxicity: Data limited, product considered low hazard for aquatic organisms
Mobility: High solubility in water, will disperse readily in aquatic environments
Persistence and Degradability: Biodegrades rapidly in soil and water
Bioaccumulation: Unlikely to bioaccumulate due to water solubility
Other Adverse Effects: No known significant effects or critical hazards for environment
Product: Dispose in accordance with local, regional, and national regulations; product itself is not classified as hazardous waste
Contaminated Packaging: Rinse containers, recycle if possible, manage as non-hazardous solid waste
Recommended Disposal Method: Incineration or landfill according to relevant legislation, prevent large volumes from entering waterways
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated as dangerous goods for land, sea, or air transport
Packing Group: Not applicable
Special Precautions: Avoid generating dust during transport, keep containers sealed and upright
Classification: Not hazardous according to global harmonized system (GHS), OSHA, EU CLP regulations
Inventory Status: Listed on TSCA, REACH, AICS, DSL, ENCS, and other international inventories
Labeling Requirements: No hazard label required for general handling
Other Regulations: Ensure use aligns with food, pharmaceutical, and workplace regulations as applicable to local jurisdiction
