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Chemical Name: Tetrahydrothiophene
Common Synonyms: Thiophane
Chemical Formula: C4H8S
Molecular Weight: 88.17 g/mol
Physical Form: Clear, colorless to pale yellow liquid, typical sulfurous odor
CAS Number: 110-01-0
Hazard Classification: Flammable liquid, harmful if swallowed, causes serious eye and skin irritation, hazardous to aquatic environments
Signal Word: Warning
Hazard Statements: Highly flammable, can form explosive mixtures with air, exposure leads to discomfort or even acute toxicity, vapors irritating to eyes and respiratory tract, persistent odor lingers on clothing or skin, headaches or nausea often reported with moderate exposure
Precautionary Advice: Prevent inhalation of vapors, avoid eye or skin contact, keep away from heat or open flames, do not release directly to environment due to water contamination risk
Substance: Tetrahydrothiophene (pure, not blended)
Concentration: 100% in most commercial settings
Impurities: Residual sulfur compounds occasionally present in trace amounts, contributing to odor and potential performance variability
Inhalation: Move affected person to fresh air immediately, lay them down comfortably, loosen clothing, watch for signs of breathing difficulty or dizziness, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, avoid reuse before laundering, monitor for irritation
Eye Contact: Rinse eyes gently under running water for at least fifteen minutes, do not delay medical review, watch for ongoing discomfort
Ingestion: Do not induce vomiting, rinse mouth if alert, seek medical advice quickly, monitor for abdominal pain or nausea
Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam, avoid direct water stream which might spread flammable liquid
Fire Hazards: Highly flammable vapor may travel along surfaces and ignite at distant locations, risk of explosion inside enclosed spaces without proper ventilation
Protective Actions: Wear self-contained breathing apparatus, chemical-resistant clothing, cool exposed containers with water spray to prevent rupture, keep personnel away from downwind smoke
Spill Response: Ventilate area, eliminate ignition sources, soak up with inert absorbent (sand, earth), collect in sealed container, avoid runoff to drains or waterways
Personal Precautions: Wear chemical splash goggles, nitrile gloves, and suitable respirator if vapor levels seem elevated, prevent skin exposure
Cleanup Advice: Dispose of contaminated material according to regulations, wash hands thoroughly after handling, keep waste segregated as flammable hazardous material
Safe Handling: Only handle in well-ventilated areas, ground and bond all containers and transfer equipment to prevent static discharge, do not smoke or use open flames near product
Storage Requirements: Store in tightly closed containers in cool, dry locations away from sunlight and incompatible substances such as oxidizers, segregate from food and household areas, use spark-proof tools and equipment
Occupational Exposure Limits: No established exposure limit by common agencies, but exposure should remain as low as feasible
Engineering Controls: Exhaust ventilation in storage or usage locations, vapor containment, explosion-proof fixtures
Personal Protection: Chemical-resistant gloves, eye protection such as safety goggles or full-face shields, flame-resistant lab coat, respirator fitted with organic vapor cartridge for high vapor areas
Appearance: Clear to pale yellow liquid
Odor: Strong, unpleasant sulfurous scent
Boiling Point: 114°C
Melting Point: -110°C
Flash Point: Approximately 10°C (closed cup)
Solubility: Slightly soluble in water, miscible with most organic solvents
Vapor Pressure: Moderate at room temperature, contributes to volatility
Density: 0.98 g/cm³ at 20°C
Chemical Stability: Remains stable in sealed containers stored under suggested conditions
Reactive Hazards: Powerful oxidizing agents trigger violent reactions, produces toxic gases like sulfur oxides and carbon disulfide on combustion, avoids exposure to heat, sparks, and static discharge
Conditions To Avoid: High temperatures, sources of ignition, incompatible chemicals
Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Effects: Irritation to eyes, nose, and throat, nausea, headache, dizziness, potential for central nervous system depression at higher exposures
Chronic Effects: Prolonged skin exposure may cause dermatitis, repeated inhalation leads to respiratory sensitivity or chronic irritation
Carcinogenicity: No evidence of carcinogenicity in humans based on available studies
Other Health Risks: Sulfur-based compounds may increase workplace sensitivity in some individuals prone to allergic reactions
Aquatic Toxicity: Harmful to aquatic life, especially in concentrated spills, long-lasting degradation products may persist
Mobility in Soil: Moderate, potential for groundwater contamination if unchecked
Persistence and Bioaccumulation: Does not readily degrade, can accumulate in soil and biological tissues over time, repeated discharge threatens local ecosystems and drinking water safety
Disposal Methods: Use an approved hazardous waste disposal service, avoid disposal through sewage or surface water outlets, containers holding residual material must be managed as hazardous waste
Environmental Cautions: Incinerate only in facilities equipped to handle sulfurous emissions, inform waste handlers about risks related to volatile organic chemicals
UN Number: UN2412
Proper Shipping Name: Tetrahydrothiophene
Packaging Group: II (significant hazard)
Transport Hazards: Class 3 (flammable liquid), containers require clear labeling, keep upright and secure during transit, movement restricted from public transport in many localities
Classification: Subject to flammable liquid guidelines under global transport and workplace safety rules, not categorized as a controlled drug or consumer product
Workplace Requirements: Employers must communicate hazards clearly, train staff on exposure risks and emergency procedures, maintain access to eyewash and shower stations
Reporting Obligations: Large-scale storage or accidental release often triggers environmental reporting under local spill and emissions laws, ongoing monitoring sometimes required near gas distribution or industrial facilities
