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Product Name: Sodium Glycerophosphate
Chemical Formula: C3H7Na2O6P
CAS Number: 1334-74-3
Intended Use: Used as a pharmaceutical excipient, nutrient supplement, and buffering agent in various industrial and laboratory applications.
Supplier Identification: Manufacturer’s name, address, and emergency contact phone number should be accessible on the packaging or upon inquiry.
Physical Hazards: Sodium Glycerophosphate appears as a white, crystalline powder that absorbs moisture from air under high humidity conditions.
Health Hazards: Dust can irritate the eyes, nose, and throat; ingestion may cause mild gastrointestinal irritation, and prolonged skin contact can trigger mild irritation or a rash. This chemical is not classified as a carcinogen, mutagen, or reproductive toxin.
Environmental Hazards: No immediate or long-term environmental risks have been identified with the regular disposal of small amounts of sodium glycerophosphate. Large releases could increase phosphorus levels in water bodies, potentially disturbing aquatic ecosystems.
NFPA Ratings: Health - 1; Flammability - 1; Reactivity - 0
Chemical Name: Sodium Glycerophosphate
Content: Contains 98-100% pure Sodium Glycerophosphate; no significant impurities relevant to health classification.
Additives: May contain trace water as moisture; other contaminants are not typically present.
Eye Contact: Immediately flush with gentle, flowing water for 15 minutes, making sure to separate eyelids to ensure complete rinsing. Remove contact lenses if present.
Skin Contact: Wash affected area with soap and water for at least 15 minutes. Remove any contaminated clothing and launder before reuse.
Inhalation: Move the individual to fresh air and keep at rest in a comfortable position. Seek medical attention if persistent breathing discomfort develops.
Ingestion: Rinse mouth with water and offer small amounts to drink if the person is conscious. Never induce vomiting. Seek medical attention for significant or large quantity exposures.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide. Choose extinguishing agents compatible with surrounding materials.
Specific Hazards: Product itself is not flammable, but containers with dust may support combustion under rare circumstances. Decomposes at very high temperature to release irritating fumes, including phosphorous oxides and sodium oxides.
Personal Protective Equipment: Firefighters must wear self-contained breathing apparatus and full protective gear to protect from potential toxic decomposition products.
Special Procedures: Avoid inhaling gases and vapor produced in a fire; keep containers cool with spray if exposed to flames.
Personal Precautions: Keep unnecessary personnel away; avoid generating dust and ventilate area. Those cleaning up should wear protective equipment, including safety goggles, gloves, and an appropriate dust mask or respirator.
Environmental Precautions: Prevent product from entering drains, sewers, or surface water. If product reaches water bodies, inform local authorities due to phosphorus content.
Methods for Cleaning Up: Collect spilled material with a clean, dry shovel and store in a suitable container for disposal. Clean affected area with water after removal.
Handling: Minimize the creation and inhalation of dust; wear appropriate PPE during transfer and handling. Do not eat, drink, or smoke while working with this material. Wash hands thoroughly at shift end.
Storage: Store tightly closed in a cool, dry, and well-ventilated area. Separate from oxidizing agents and strong acids. Protect from moisture and direct sunlight. Keep container labels visible and legible.
Incompatible Materials: Strong oxidizers, strong acids, and moisture lead to chemical degradation and could cause hazardous conditions.
Occupational Exposure Limits: No occupational exposure limits established for sodium glycerophosphate; controlling dust is important for overall air quality.
Engineering Controls: Use process enclosures, local exhaust ventilation, or general ventilation systems to control airborne dust and keep exposure levels as low as possible.
Personal Protective Equipment: Use safety goggles to prevent eye contact, gloves (nitrile or PVC) for hand protection, and a NIOSH-approved dust respirator if dust generation is significant. Laboratory coat or apron recommended.
Hygiene Measures: Remove contaminated clothing after work and launder before reuse. Wash hands after handling material and before eating or drinking.
Appearance: White, crystalline powder with no characteristic odor.
pH (1% solution): 9.5–10.5
Melting Point: Decomposes before melting; decomposition temperature approximately 150°C (302°F).
Solubility: Soluble in cold water; insoluble in alcohol or ether.
Density: Approximately 1.7 g/cm³
Vapor Pressure: Not applicable; solid at room temperature.
Boiling Point: Not applicable (decomposes).
Evaporation Rate: Not applicable.
Other Physical Data: Tends to absorb moisture from air (hygroscopic).
Chemical Stability: Stable under recommended storage and handling conditions.
Possibility of Hazardous Reactions: Not likely to occur under normal use; contact with strong oxidizing agents or strong acids may cause hazardous degradation.
Conditions to Avoid: Protect from humidity, excessive heat, and sources of ignition.
Incompatible Materials: Strong oxidizers, acids, and moisture accelerate decomposition.
Decomposition Products: Produces sodium oxides and phosphorus oxides at elevated temperatures; may release irritating vapors.
Likely Routes of Exposure: Inhalation, ingestion, skin, and eye contact are the most common exposure routes in workplaces and laboratories.
Acute Effects: Low toxicity. Inhalation can irritate the respiratory tract; contact causes mild skin or eye irritation; ingestion in moderate amounts does not present serious risk but may upset the digestive system.
Chronic Effects: No data suggest chronic toxicity with standard handling; prolonged or repeated exposure of large quantities not recommended.
Carcinogenicity: Not listed as carcinogenic by OSHA, NTP, or IARC.
Specific Data: Oral LD50 (rat) exceeds 5,000 mg/kg. No anticipated reproductive or developmental toxicity.
Aquatic Toxicity: Phosphate release can promote algal blooms and disturb aquatic balance if large amounts enter waterways.
Persistence and Degradability: Product gradually breaks down in water, contributing inorganic phosphate ions; does not bioaccumulate.
Mobility in Soil: Highly soluble, diffuses rapidly into soil and water.
Bioaccumulative Potential: Minimal, does not build up in organisms.
Other Adverse Effects: Avoid introducing large quantities to the environment; responsible use and disposal are essential.
Product Disposal: Dispose unused or waste material with licensed chemical waste disposal companies, observing all local, regional, and national guidelines for phosphate-containing compounds.
Packaging Disposal: Containers should be rinsed thoroughly and recycled or sent for landfill depending on local regulations. Do not reuse packaging for food or drink.
Waste Codes: Not classified as hazardous waste under most disposal regulations, but confirm with local authority.
UN Number: Not regulated as a hazardous material for air, sea, or land transport.
Proper Shipping Name: Sodium Glycerophosphate
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not regarded as environmentally hazardous for transport, but avoid large spills.
Special Precautions for User: Store dry; protect containers from mechanical damage.
OSHA: Not classified as hazardous under the OSHA Hazard Communication Standard.
TSCA: Listed on the U.S. Toxic Substances Control Act Inventory.
REACH: Not subject to registration as a substance under the European REACH regulation.
Other Regulations: Consider reporting requirements under the Clean Water Act and CERCLA if disposed of in large amounts or into natural waters.
Labeling Requirements: Ensure product is clearly labeled for safe identification. Includes hazard phrases for minor irritation and environmental advice.
