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Product Name: Penicillin Sodium
Synonyms: Benzylpenicillin sodium salt, Penicillin-G sodium
CAS Number: 69-57-8
Recommended Use: Antibiotic for bacterial infection treatment
Supplier Information: Contact details available on request, main distributors and manufacturers cater to healthcare settings
Emergency Phone: Standard emergency contact lines for chemical exposures in your area
GHS Classification: Sensitizing substance, possible respiratory irritant
Signal Word: Warning
Hazard Statements: May cause allergic reactions, can trigger asthma-like symptoms, may irritate eyes, skin, and respiratory tract
Pictograms: Exclamation mark (irritant), health hazard (sensitizer)
Precautionary Statements: Wear protective gloves, avoid inhalation of dust, keep container tightly closed, seek medical care for exposure symptoms
Other Risks: Environmental impact in water bodies due to antimicrobial resistance
Chemical Name: Penicillin Sodium
Purity: Typically above 98% for pharmaceutical grade
Formula: C16H17N2NaO4S
Impurities: Possible trace solvents or synthesis byproducts at non-toxic levels
Other Components: Small residual quantities of related penicillins or excipient from formulation, as tested by manufacturers
Inhalation: Remove to fresh air immediately, provide oxygen if breathing is difficult, seek medical input for persistent symptoms
Skin Contact: Wash vigorously with soap and water, remove contaminated clothes, consult physician for rash or irritation
Eye Contact: Rinse gently with plenty of water for fifteen minutes, do not rub, obtain medical opinion if pain or redness continues
Ingestion: Rinse mouth, give water if conscious, do not induce vomiting, call poison control center or emergency department
Allergic Reaction: For signs of anaphylaxis (wheezing, swelling, rapid pulse), use epinephrine auto-injector if available and seek emergency treatment
Suitable Extinguishing Media: Water spray, dry powder, CO2, foam
Unsuitable Media: High-pressure water jets may spread powder
Special Hazards: Decomposition in fire produces toxic fumes like sulfur oxides, nitrogen oxides
Protective Equipment: Self-contained breathing apparatus, fire-resistant clothing, full face protection
Advice for Firefighters: Avoid inhaling fumes or dust generated by burning material, control run-off to prevent environmental contamination
Personal Precautions: Wear gloves, goggles, suitable mask, limit dust creation
Environmental Precautions: Prevent powder from entering drains, soil, or water bodies
Cleaning Methods: Avoid dry sweeping, dampen with water and scoop into waste container, ventilate area thoroughly
Disposal of Cleanup Waste: Place debris and cleaning media in sealed, labeled containers for hazardous waste handling
Notification: Report larger spills to regulatory authorities according to local requirements
Handling: Use in well-ventilated spaces, avoid dust generation, wear personal protection, handle only by trained personnel
Storage Conditions: Store in tightly sealed containers at 2-8°C (refrigerated), keep away from light, humidity, and incompatible chemicals
Incompatibles: Strong oxidizing agents, acids, heavy metals
Other Guidance: Protect from excess heat, store separate from foodstuffs or animal feed
Exposure Limits: No established occupational exposure limit, minimize all contact as allergic effects are unpredictable
Engineering Controls: Local exhaust ventilation, enclosed process handling
Personal Protection – Eyes: Chemical safety goggles
Personal Protection – Hands: Impermeable gloves (nitrile or rubber recommended)
Personal Protection – Respiratory: Use respirator for dusts, especially when working outside a ventilated hood
Personal Protection – Skin: Protective lab coats, long sleeves, avoid direct skin contact
Appearance: White or off-white, fine powder
Odor: Not strong, faint medicinal scent
pH (10% solution): Ranges 6.0–8.0
Melting Point: Decomposes above 200°C
Solubility: Freely soluble in water, limited solubility in alcohol
Boiling Point: Not applicable, decomposes before boiling
Vapor Pressure: Negligible
Relative Density: 1.2–1.3 g/cm³
Other Properties: Stable under recommended storage, hygroscopic so absorbs moisture from air
Chemical Stability: Stable in dry, cool storage, degrades with heat, moisture, and light
Reactivity: May react with strong oxidizers and acids, undergoes hydrolysis in aqueous solutions
Decomposition: Produces sulfur oxides, nitrogen oxides, carbon monoxide or dioxide
Hazardous Polymerization: Will not occur
Other Incompatibilities: Metals such as iron and copper expedite breakdown of penicillin structure
Routes of Exposure: Inhalation, skin contact, ingestion, accidental injection
Acute Effects: Main risk is allergic reaction – hives, rash, breathing difficulty, anaphylactic shock
Chronic Effects: Prolonged exposure may lead to sensitization, some individuals develop severe allergies after repeated contact
LD50 Values: 8900 mg/kg (oral, mouse)
Other Effects: May irritate respiratory and digestive mucosa, no evidence for carcinogenicity, teratogenicity, or reproductive toxicity based on available data
Occupational Experience: Healthcare workers can acquire allergy from repeated handling if exposure isn’t well controlled
Aquatic Toxicity: Toxic to aquatic microorganisms, data on fish or invertebrate toxicity limited
Persistence: Penicillin breaks down in environment but can promote antibiotic resistance at very low concentrations
Mobility: Dissolves in water, can travel with run-off
Bioaccumulation Potential: Low, rapid breakdown typically prevents accumulation
Other Concerns: Pharmaceuticals in wastewater—like penicillins—can disturb microbial communities and influence microbial flora resistance patterns
Safe Disposal: Treat as pharmaceutical waste, incinerate in authorized facility, consultation with waste contractor recommended
Container Disposal: Triple-rinse then puncture and send to chemical waste stream
Legal Requirements: Follow all local, state, and federal regulations on pharmaceutical or hazardous waste
Do Not: Discard in household trash, pour down drain, or release to the environment
UN Number: Not classified under most international transport conventions as dangerous
DOT/IATA/IMDG Class: Not regulated as a hazardous material for transport
Packing Group: Not applicable
Labeling: Standard commercial labeling applies
Special Precautions: Protect from moisture and breakage, avoid temperature extremes while in transit
OSHA Status: Not specifically listed as hazardous; employers must manage as potential allergen
TSCA Status: Not listed
SARA Title III: Not considered reportable
WHMIS (Canada): Not classified as controlled product
EU Regulations: Not classified as hazardous under Regulation (EC) No 1272/2008
Recommendations: Always check current national and local laws for the most up-to-date guidelines regarding drugs like penicillin sodium
Environmental Release Reporting: Required if significant spill reaches local waters or treatment facilities
