© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Nifuratel
Chemical Name: 1-(5-nitro-2-furfurylideneamino)-2-methylthio-imidazolidine
CAS Number: 4936-47-4
Recommended Use: Pharmaceutical intermediate, research chemical
Manufacturer: [Enter manufacturer info]
Contact Information: [Enter emergency phone and address]
Synonyms: Macmiror; Nifuratelum
Emergency Phone Number: [Add regional poison control contacts]
Hazard Classification: Eye irritation (Category 2A), Skin sensitization (Category 1), Specific target organ toxicity — single exposure (Category 3), Carcinogenicity (Category 2)
Label Elements: Signal word: Warning. Hazard statements include: May cause eye irritation, May cause allergic skin reaction, Suspected of causing cancer, May cause respiratory irritation.
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Avoid breathing dust, Wash hands thoroughly after handling, Wear protective gloves, clothing, and eye protection, Use only outdoors or in a well-ventilated area, Dispose of contents in accordance with local regulations.
Potential Health Effects: Inhalation of powder may irritate respiratory tract. Skin or eye contact can cause irritation or allergic reactions. Prolonged or repeated exposure may lead to organ effects.
Environmental Hazards: Harmful to aquatic life with long-lasting effects.
Chemical: Nifuratel
Common Name: Nifuratel
Purity: ≥ 98% (for pharmaceutical grade)
Impurities: ≤ 2% (may include related nitrofuran derivatives, identified during QC testing)
Molecular Formula: C10H11N3O5S
Molecular Weight: 301.28 g/mol
Other Ingredients: None for pure API; for formulated products, refer to specific excipient list.
CAS Number: 4936-47-4
Inhalation: Remove to fresh air, keep at rest, seek medical advice. Symptoms like coughing or shortness of breath need immediate attention.
Skin Contact: Remove contaminated clothing, rinse skin with water, wash with soap. If irritation or allergic reaction develops, consult physician.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing. If eye irritation persists, get medical advice.
Ingestion: Rinse mouth, do not induce vomiting. Get medical advice.
Rescue Personnel Protection: Use protective gloves, goggles, and avoid inhalation of dust.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide.
Specific Hazards: May emit toxic fumes containing nitrogen oxides, sulfur oxides, carbon oxides when burned.
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing.
Advice for Firefighters: Prevent contamination of water sources by runoff from fire control.
Special Procedures: Move containers from fire area if safe, cool exposed containers with water spray.
Personal Precautions: Wear gloves, goggles, mask to avoid inhalation or contact. Isolate area, ventilate.
Environmental Precautions: Prevent further spillage, entry into drains or environment. Notify appropriate authorities if contamination occurs.
Methods for Containment: Contain spill with inert material (sand, earth).
Clean-up Methods: Scoop up and place in labeled waste container for disposal. Wash area with water after removal.
Disposal: Dispose absorbents and residues following regulatory requirements.
Precautions for Safe Handling: Avoid inhalation, contact with skin or eyes. Do not eat, drink, or smoke while using. Use in a well-ventilated area.
Conditions for Safe Storage: Store in tightly sealed container, away from light, moisture, and incompatible substances (e.g., strong oxidizers).
Recommended Storage Temperature: Between 2°C and 8°C.
Shelf Life: Typically stable for 3–5 years if unopened and stored correctly.
Incompatible Materials: Oxidizing agents, strong bases, acids.
Exposure Limits: No workplace exposure limits established for nifuratel. As with many pharmaceutical intermediates, exposure should be minimized.
Engineering Controls: Use local exhaust or general ventilation; handle powder in chemical fume hood.
Personal Protective Equipment: Safety goggles, nitrile or neoprene gloves, laboratory coat, approved N95 or P2 respirator if dust forms.
Hygiene Measures: Wash hands after handling, remove contaminated clothing before entering eating areas.
Environmental Controls: Avoid dust formation; use HEPA filtration for contaminated air.
Appearance: Yellow to orange crystalline powder
Odor: Odorless or faint characteristic smell
pH: Not applicable (insoluble in water)
Melting Point/Range: 184–190°C
Boiling Point: Decomposes before boiling
Flash Point: Not determined (decomposes on heating)
Solubility: Slightly soluble in water, readily soluble in alcohol, chloroform, and acetone
Vapor Pressure: Not applicable at ambient temperature
Relative Density: 1.52 g/cm³ (approximate)
Partition Coefficient: Not available
Auto-Ignition Temperature: Not available
Chemical Stability: Stable under recommended handling and storage conditions.
Possibility of Hazardous Reactions: No hazardous polymerization expected under normal use.
Conditions to Avoid: Exposure to strong light, moisture, elevated temperatures, open flame.
Incompatible Materials: Strong oxidizing agents, acids, alkalis.
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides, toxic fumes during decomposition or combustion.
Acute Toxicity: LD50 (oral, rat): > 2000 mg/kg. Low acute toxicity via oral exposure in animal studies.
Skin Corrosion/Irritation: Mild irritant to skin by animal data.
Serious Eye Damage/Irritation: Causes reversible eye irritation.
Respiratory or Skin Sensitization: Sensitizing in repeated exposure contexts; may provoke allergic reactions.
Carcinogenicity: Animal studies suggest possible carcinogenic potential; not classified by IARC, NTP, or OSHA.
Reproductive Toxicity: Not enough human or animal data to determine risk.
Other Information: Chronic exposure has demonstrated effects on liver and kidneys in animals.
Aquatic Toxicity: Harmful to aquatic organisms, long-term adverse effects possible downstream.
Persistence and Degradability: Not readily biodegradable in standard environmental settings.
Bioaccumulation Potential: Expected to have low potential for bioaccumulation.
Soil Mobility: Moderate mobility due to low solubility.
Other Adverse Effects: Avoid release to waterways or sewage systems.
Disposal Methods: Incinerate in chemical incinerator equipped with afterburner and scrubber. Dispose according to local, regional, national regulations.
Packaging Disposal: Treat as hazardous waste. Decontaminate containers before recycling or disposal.
Environmental Precautions: Prevent material from entering surface water, groundwater, or soil.
Waste Code: Refer to local hazardous waste classifications.
UN Number: Not classified as dangerous goods under current UN transport rules.
Proper Shipping Name: Not regulated.
Transport Hazard Class: Not applicable.
Packing Group: Not assigned.
Special Precautions: Avoid damage to containers. Prevent spillage. Ship to avoid extreme temperature and physical shocks.
Safety, Health and Environmental Regulations: Not listed as a controlled substance under Annex I, II, III of REACH, not classed as hazardous under US TSCA, CERCLA, SARA Title III.
Labeling Requirements: GHS, CLP, and OSHA-compliant hazard and precautionary statements apply.
Workplace Limits: No established occupational exposure limits.
Inventory Status: Included in EINECS/ELINCS, TSCA, DSL
Restriction: Consult national/local regulations regarding pharmaceutical and laboratory use. Not for food or household applications.
