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Product Name: Monensin Sodium
Chemical Formula: C36H61NaO11
CAS Number: 22373-78-0
Synonyms: Monensin sodium salt, Coban, Rumensin
Intended Use: Feed additive for coccidiosis prevention in livestock
Manufacturer: Industry-standard suppliers and global veterinary product manufacturers
Contact Information: Emergency telephone numbers available through supplier’s safety coordinator and national poison control centers
GHS Classification: Acute oral toxicity (Category 2), Specific target organ toxicity - repeated exposure (Category 2)
Label Elements: Skull and crossbones, exclamation mark pictograms
Signal Word: Danger
Hazard Statements: May be fatal if swallowed, toxic in contact with skin, toxic to aquatic life, may cause organ damage through prolonged or repeated exposure
Precautionary Statements: Avoid all contact, do not breathe dust, handle with proper protection, wash thoroughly after handling, avoid release to environment, dispose of contents in line with regulations
Chemical Name: Monensin sodium
Concentration: 90-100% active ingredient in technical grade
Impurities: Trace residual solvents and byproducts from fermentation (proprietary profiles available upon request)
Molecular Weight: 693.86
Component Analysis: Solid-state mixture may contain anti-caking agents in some feed formulations
Inhalation: Remove victim to fresh air, maintain respiration, seek immediate medical help
Skin Contact: Remove contaminated clothing, rinse skin with soap and water, obtain medical assistance for persistent irritation
Eye Contact: Rinse thoroughly with plenty of water for at least 15 minutes and seek care promptly
Ingestion: Rinse mouth if conscious, do not induce vomiting, obtain urgent medical attention; toxic effects can occur rapidly including muscle weakness, cardiovascular effects, and respiratory depression
Most Important Symptoms: Nausea, vomiting, incoordination, muscle weakness, cardiac arrhythmias
Advice to Physician: Treat symptomatically with close monitoring of cardiac and neuromuscular function
Flammability: Organic powder, may form combustible dust concentrations in air
Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray for small fires; avoid high-pressure streams that may disperse dust
Special Hazards: Emission of toxic fumes of carbon oxides and sodium oxides in fire
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective clothing
Personal Precautions: Evacuate area, wear respiratory protection, chemical goggles, and gloves
Environmental Precautions: Prevent entry into waterways, sewers, and soil to avoid ecological impacts
Clean-Up Methods: Sweep up spills, avoid creating dust, collect in sealed containers for safe disposal, ventilate area thoroughly, decontaminate surfaces with detergent
Disposal of Residues: Approach as aggressive chemical waste, ensuring containment and handling through specialized chemical disposal firms or designated hazardous waste facilities
Handling: Handle only in well-ventilated zones, avoid breathing dust, prevent skin and eye contact, avoid eating, drinking, or smoking while handling product, ensure containers are tightly closed
Storage: Store in original containers, away from food and feed, under cool, dry, and ventilated conditions, protect from moisture and incompatible substances, limit stacking height to prevent container rupture; prohibit access to unauthorized personnel
Engineering Controls: Mechanical ventilation, dust extraction and enclosures at transfer points, process isolation, negative-pressure rooms in bulk handling zones
Personal Protection: NIOSH-approved respirators for particulate matter, safety goggles or face shields, impervious gloves, full protective clothing covering all exposed skin, safety boots
Hygiene Measures: Wash hands and face thoroughly after handling and before eating or using restroom, clean contaminated clothing before reuse
Exposure Limit Values: No established national occupational exposure limits, but animal studies indicate effects at low exposure so minimal contact protocol strongly advised
Appearance: Off-white to light brown crystalline powder
Odor: Mild, characteristic odor
pH: 5.5-7.5 (1% solution)
Solubility: Slightly soluble in water, soluble in methanol and ethanol
Boiling Point: Not applicable (decomposes before boiling)
Melting Point: Decomposes above 266°C (data based on thermal gravimetric analysis)
Vapor Pressure: Not volatile under standard conditions
Density: 1.10-1.25 g/cm³
Partition Coefficient (log Kow): Estimated at 1.4 (favoring slight bioaccumulation in aquatic organisms)
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Extreme heat, exposure to open flame, excessive moisture, direct sunlight
Materials to Avoid: Strong acids, oxidizing agents, reducing agents
Hazardous Decomposition: Releases carbon oxides and sodium oxide if combusted; thermal degradation may produce other toxic fumes
Reactivity: Inert to most feed and packaging materials under dry conditions
Acute Toxicity: Highly toxic by ingestion, especially to horses, dogs, and certain avian species; toxicity in humans manifests in muscle, neurological, and cardiac effects; oral LD50 in rats 20 mg/kg
Chronic Exposure: Repeated low-dose exposure may induce peripheral neuropathy, muscle atrophy, congestive heart failure in susceptible animals
Skin/Eye Irritation: Causes irritation and redness; prolonged contact intensifies symptoms
Sensitization: Rare, but possible with repeated handling
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No convincing evidence in animal studies of carcinogenic or mutagenic effects; reproductive toxicity at high doses in laboratory animals
Aquatic Toxicity: Toxic to fish and aquatic invertebrates; LC50 in Daphnia magna (48h) approx. 1 mg/L
Persistence: Moderately persistent in water and soil; risk of bioaccumulation in aquatic organisms if released through wastewater or runoff
Mobility: Limited in soil due to adsorption to organic matter; leaching risk present in sandy soils
Biodegradability: Partially biodegradable but may persist under certain anaerobic conditions
Other Adverse Effects: Can disrupt microbial populations in water or soil ecosystems if improperly discarded, risk of resistance development in target organisms due to sublethal concentrations in agriculture runoff
Waste Management: Incinerate at regulated facility or landfilled in accordance with local environmental protection legislation
Container Disposal: Triple rinse, puncture, render unusable; recycle or dispose at approved hazardous waste sites
Precautions: Prevent contamination of surface water, groundwater, and soil; do not discharge to drains
Regulatory Compliance: Follow all community, regional, and national waste management guidelines; engage specialized chemical waste contractors where available
UN Number: 2811 (for toxic solid, organic, n.o.s.)
Proper Shipping Name: Toxic solid, organic, n.o.s. (Monensin sodium)
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Labels: Toxic
Transport Requirements: Keep containers sealed and secure during transit, avoid release and spillage, communicate hazards clearly to carriers and first responders
Labelling: In line with the Globally Harmonized System (GHS), relevant hazard pictograms, signal words, and precautionary statements mandated
Registration: Approved for restricted veterinary use under many national frameworks (including FDA, EMA, PMRA)
Occupational Health Legislation: Subject to workplace chemical safety directives and exposure control laws
Environmental Release Controls: Agricultural agencies may require recordkeeping, stewardship programs, and monitoring of environmental residues
Additional Notes: Not permitted for human use, sale and transport subject to authorization and controlled substance tracking within regulated sectors
