Mellocillin sodium did not spring up overnight. Its story stretches back to the surge of beta-lactam antibiotic research in the mid-20th century, when scientists scrambled to outpace fast-evolving bacterial threats. Over the past decades, chemists tackled instability and inconsistent results in early forms of penicillin derivatives. Drawing on breakthroughs in organic chemistry, Mellocillin sodium took shape as a semisynthetic option with improved activity against resistant pathogens. Growing up in a pharmacy family, it becomes apparent how patent races and scientific rivalry in those formative years shaped every bottle and vial ending up on hospital shelves today. Pharmaceutical archives show Mellocillin sodium earning regulatory nods in regions where gram-negative coverage demanded new solutions, tracing patent filings and clinical trial records back to the late 1970s. The intent carried through generations has always been about broadening the possibilities in infection care—closing the door on sepsis deaths that once seemed unavoidable.
Mellocillin sodium, a blend of science and purpose, lands in hospital formularies as a parenteral antibiotic aimed at battling bacterial infections caused by susceptible strains. It falls into the carboxypenicillin family, sharing traits with agents like ticarcillin, yet bringing its unique activity profile thanks to structural tweaks. One clear sign of its impact: fewer patients forced to step up to more toxic, last-resort antibiotics because Mellocillin sodium can knock down many stubborn offenders early. Manufacturers typically provide it as a sterile powder meant for reconstitution, so pharmacy techs don’t wrestle with stability issues that plagued older carbenicillin-based options. Its sodium salt form boosts solubility and simplifies intravenous delivery, a practical trick anyone who’s mixed antibiotics late at night can appreciate.
White to off-white in color, Mellocillin sodium looks much like its penicillin cousins, but it quickly distinguishes itself in a lab. Its crystalline powder dissolves rapidly in water for injection, releasing a faint chemical scent characteristic of beta-lactam agents. Doing lab preps, you see the pH of its freshly mixed solution, usually landing around 6.5–8.0, makes it easier on veins than some harsh alternatives. The melting point sits high over 200 degrees Celsius, so standard room temperatures never threaten its integrity. Chemically, the sodium cation swaps in for a hydrogen atom, enhancing solubility and lending the powder a slightly salty taste—though you’ll never catch anyone in the lab sampling it for that reason. Its molecular weight and formula, tweaked over years, allow for streamlined pharmacokinetics—cycling through the bloodstream and kidneys with predictable speed.
Accurate labeling and specifications go beyond compliance; they protect lives, especially during midnight dosing checks. Most Mellocillin sodium vials ship in doses ranging from 1 to 5 grams. Labels must list the exact milligram content, the sodium ion load—crucial for patients on salt-restricted diets—and complete manufacturing and expiration details. I’ve seen more than one nurse catch a near mistake at three in the morning thanks to clear labels and proper batch coding. Typical quality standards demand a pH range closely monitored for injection tolerability, and microbial contamination standards reflect how antibiotics, ironically, become dangers if they carry infection themselves. Pharmacopoeia like the USP and European equivalents line out specific purity tests, water content thresholds, and acceptable particulate matter. Support documents explain reconstitution procedures and dosing calculations, not just to avoid lawsuits but as a reminder of the hands-on risks in critical care.
Manufacturing Mellocillin sodium involves more than mixing ingredients. The journey begins with fermentation—bioreactors grow penicillin-producing organisms, feeding them carefully balanced nutrients. Chemists then harvest the raw penicillin and plunge it through synthetic reactions to yield the Mellocillin backbone, pulling in acylation steps and carefully regulated pH to avoid unwanted byproducts. Final conversion to the sodium salt turns the unstable acid into a form stable enough for shipping and storage. Quality assurance follows each batch, testing for minute contaminants, confirming crystalline form, and tagging each lot for full traceability. I spent summers shadowing factory techs, and no part of the operation leaves room for shortcuts. The complexity reflects the stakes—each gram represents hundreds of hours and thousands of dollars, all to guarantee a few days’ supply during a hospital outbreak.
The resilience of Mellocillin sodium depends on its sturdy beta-lactam ring, a chemical structure famous for its capacity to cripple bacterial enzymes. Structural chemists tinker at the 6-APA nucleus, fixing in carboxyl and aromatic groups that change how enzymes interact at infection sites. In the real world, the chemical methods used to attach those groups—usually amidation and acylation reactions—trigger heated debate about efficiency, purity, and yield. Reactivity tests under different pH and thermal conditions tell manufacturers how the molecule will behave under field stress. Every time a batch leaves the plant, it has weathered scrutiny at the atomic level—mass spectrometry, NMR, and crystallography checking for isomers or potential loss of antibiotic power. Chemical modification continues in research labs, always searching for new side chains that might break through stubborn resistance without dragging along greater toxicity.
Doctors and pharmacists don’t always call it Mellocillin sodium. Across the globe, it responds to alternative spellings—sometimes seen as Mepicillin, or in older handbooks as Neopenatrin Sodium, reflecting past branding attempts. International suppliers print different trade names, which confuses staff during supply chain bottlenecks. In the U.S., nonproprietary naming keeps it in the sodium salt category, following FDA labeling guidelines. Pharmacists juggling shortages depend on familiarity with synonyms to avoid dispensing mistakes; a mismatch between prescription and inventory name has caused more than one after-hours phone call.
Antibiotics like Mellocillin sodium reward operators who follow safety routines. Pharmacy staff handling dry powders work inside laminar flow hoods to shield themselves and the product from exposure. Product safety sheets warn about allergy risks, especially for those sensitized to penicillin derivatives. Hospitals check every patient’s allergy history right before a dose. Proper handling means using gloves, dust masks, and careful hand washing, since even small particles become airborne during reconstitution. Facility managers enforce cold storage at 2–8 degrees Celsius to maintain potency up to expiration. The strictest hospitals use electronic inventory to flag potential cross-contamination between antibiotics, trying to block even remote chances of error. Waste management protocols sort Mellocillin sodium in the hazardous pharmaceutical category, keeping it away from regular landfill or wastewater to avoid environmental contamination.
Mellocillin sodium lands in the hands of infectious disease doctors looking for broad-spectrum coverage. Emergency departments reach for it when gram-negative bacteria threaten to overwhelm patients with sepsis or complicated respiratory infections. Hospitals value it in cases where resistance to basic penicillins or cephalosporins has crept up. It often plays backup to carbapenems, delaying the use of even broader or more toxic options. In resource-limited settings, its stability and solubility allow for reliable reconstitution under less-than-ideal conditions. Rural hospitals, where broad-spectrum agents are gold, rely on it when waiting for culture results takes too long. Despite newer antibiotics flooding the market yearly, Mellocillin sodium still claims space on formularies, especially where cost, stability, and a wide safety margin matter most.
New resistance patterns force researchers back to the drawing board every year. Mellocillin sodium’s core structure inspires ongoing experiments to tweak its activity or extend its lifespan against emerging threats. Labs push molecular modeling and combinatorial chemistry, aiming to sharpen activity against beta-lactamase producers that have learned to destroy less robust drugs. Drug development teams invest in formulations that offer extended dosing intervals, lessening the burden on nursing staff and reducing chances for dose errors. As antibiotics face growing scrutiny for environmental persistence, research pivots toward bioengineered strains capable of degrading unmetabolized Mellocillin sodium in wastewater. The pace of development never lets up—pharma firms host hackathons and simulation labs, fusing clinical insight with chemical know-how. Each bottle sitting in a drug cabinet comes at the end of years of research, failed syntheses, and what-ifs, showing science in motion rather than in stasis.
No antibiotic gets used without a constant watch for unexpected harm. Mellocillin sodium undergoes extensive animal and human testing to map out its toxicology. Early studies track dose-dependent kidney and liver impacts, essential for dialysis patients who line many hospital wards. Immunologists watch for rare but dangerous anaphylactic reactions, cataloging every twitch, rash, and airway constriction. Cardiac monitoring helps spot sodium load impacts, especially in elderly or heart failure patients. Rat and rabbit models, though falling short of the full human picture, uncover clues about chronic exposure risks. I’ve seen clinical pharmacists sift through adverse event data, ready to flag concerns to regulatory agencies even after decades of use. The challenge is always about finding the narrowest gap between too low to cure and high enough to harm.
Antibiotic development never stands still. Mellocillin sodium’s journey is far from over as resistance patterns mutate and new diagnostic technologies come online. The future likely involves pairing the drug with cutting-edge rapid diagnostic systems, using machine learning to dose more precisely according to individual metabolism and infection profiles. Environmental stewardship will demand biodegradable formulations, reducing traces that linger in rivers and soil. Supply chain improvements will target more stable packaging and single-dose vials, trimming waste and error risks. Collaborative research projects may explore hybrids, melding Mellocillin sodium’s strengths with next-generation molecules. The stakes rise as superbugs carve out new resistance mechanisms—yet scientists, clinicians, and pharmacists show every day that thoughtful, realistic innovation keeps old weapons like Mellocillin sodium relevant, safe, and powerful against the constant threat of infection.
Mellocillin Sodium often shows up on pharmacy stock lists in hospitals, but its story rarely makes headlines. This antibiotic belongs to the penicillin family, and doctors reach for it when infections refuse to back down. Unlike older penicillins, it can tackle a broader range of bacteria. Its structure offers protection against enzymes that usually knock out regular penicillins before they even get started.
Doctors use Mellocillin Sodium for tough bacterial infections, and it especially helps in cases where other options fail. Plenty of patients arrive in hospitals with complicated cases: think bone infections, stubborn cases of pneumonia, urinary tract infections resistant to the standard pills, or abdominal infections that don’t budge. In these situations, regular antibiotics wave the white flag. Mellocillin steps in and gets to work. For critically ill patients, getting the right drug fast makes all the difference. In my experience shadowing infection specialists, they look for drugs like this when every hour matters. Fast-acting options like this can mean safer recoveries and fewer days lying in a hospital bed.
It’s easy to take antibiotics for granted. The truth is, every year brings new stories of bacteria adapting. These “superbugs” laugh off the old pills. The Centers for Disease Control and Prevention keeps sounding the alarm on this trend. Mellocillin fills a part of the gap, especially before doctors have results from lab tests. Sometimes that window—waiting for test results—can mean life or death in a hospital setting. Doctors can shoot Mellocillin into the bloodstream and target infections fast, instead of gambling with older drugs.
Reports from major infectious disease journals point out that Mellocillin shows good results against bacteria called enterobacteria. These often cause hard-to-treat infections in the gut and urinary tract. In places where resistance patterns keep shifting, having another tool ready can spare patients unnecessary complications. The way Mellocillin works also protects good bacteria in the stomach a bit better, compared to some broad-spectrum drugs that wreck the gut’s balance.
Doctors can’t just hand out Mellocillin like candy. Every time an antibiotic enters circulation, bacteria get another shot at learning defense tricks. Use something too much, and pretty soon, it joins the long list of drugs that don’t work anymore. I remember one senior doctor explaining that every new antibiotic is like a rare coin—you spend it only when you must. Mellocillin fits that idea. The World Health Organization keeps warning against overuse of antibiotics precisely because resistance never sleeps.
Mellocillin isn’t without risk. Some patients have a history of allergies to penicillins, and that makes this drug dangerous for them. Doctors also keep a close watch on kidney and liver function, because the body needs to metabolize the drug safely. Side effects like diarrhea or rashes still happen, even when used correctly. Good infection control means knowing exactly when a powerful drug is needed. Testing and advice from pharmacists help guide safe choices.
Government agencies and health systems keep investing in better lab diagnostics. Faster results mean doctors can switch from a general drug to a specific one, preserving drugs like Mellocillin for battles that truly need them. Education matters too, both for providers and the public. Taking antibiotics for viral infections, or stopping them halfway, only worsens the resistance crisis.
Every day in the clinic, the balance between powerful antibiotics and careful stewardship plays out. Drugs like Mellocillin Sodium stand as proof that medicine still has cards to play against stubborn infections. Smart use and ongoing research keep these tools working—for today’s patients and those down the line.
Mellocillin sodium stands out as a reliable penicillin antibiotic. Over some years in hospital pharmacies and working with doctors on the ward, you start to see how details in preparation make a difference. Mixing the drug with the right fluid and delivering it in the right way brings the benefits we hope for while cutting down the risk of problems. If a nurse skips a step or a pharmacist isn’t alerted to allergies, the chances of reactions or drug failures rise.
Oral versions of antibiotics like amoxicillin do their job for many illnesses. Mellocillin sodium asks for a bit more respect. It gets injected either into a vein (IV) or a muscle (IM). This isn’t just habit—it boils down to the medicine’s structure. Mellocillin breaks down in the gut, so taking it by mouth wastes both money and time. Hospitals use it for tough infections where strong and steady blood levels count, such as severe sepsis or hard-to-treat urinary infections.
Sterility forms the backbone of any injectable drug. In practice, prepping mellocillin sodium powder for injection means picking the right diluent—normal saline works in most cases, but sometimes glucose is okay. The pharmacist grabs sterile water if nothing else will do. Quick checks for cloudiness, particles, or color changes block a lot of errors before the syringe gets anywhere near the patient. Antibiotic errors sometimes come from rushing this stage, so extra hands and a double-check go a long way.
Taking care of children or frail seniors always puts dosing front and center. A healthy adult can handle larger doses, but smaller bodies and older adults often have weaker kidneys or more sensitive livers. Dose adjustments prevent medicine from piling up, which stops things like neurotoxicity and allergic rashes. Checking a patient’s weight, history, and current kidney function feels like a nuisance routine—until the day it catches a near-miss. Pharmacists who keep a shared chart for allergies and recent bloodwork catch more problems before they land at the bedside.
The speed of infusion affects comfort and side effects. Quick IV “bolus” pushes sometimes spark local pain or vein inflammation, especially in kids. Most hospital guidelines recommend slow infusions over at least 30 minutes. For deep muscle shots, rotating injection sites limits soreness and injection lumps. In practice, giving the patient choices (leg or arm, left or right) sometimes helps them feel more in control—a small perk when you’re fighting infection.
Allergies shape everything with penicillins. Skin rashes and breathing problems hit fast and hard if missed. In my own experience, double-checking an allergy history—even reading it out loud—builds trust and cuts errors. For side effects, keeping an eye out for diarrhea, mouth sores, or subtle signs, like confusion in older adults, catches complications early. Reporting any issues to the doctor starts a quick response, whether that means dose tweaking or switching drugs.
Good administration means more than mixing and injecting. Nurses, pharmacists, and doctors chat about dosing and watch for side effects. Patients who know why a drug goes into the vein, not the mouth, can speak up when something feels off. In my top moments at the hospital, a well-informed patient or a sharp-eyed nurse spots an early issue, and care improves because of it. Getting everyone involved creates better outcomes and stronger trust in what we do.
Doctors use Mellocillin Sodium to treat serious bacterial infections, counting on it to work fast against a long list of bacteria. Most people never hear about it unless an infection gets complicated or common antibiotics stop working. Like every strong weapon in medicine, this drug brings its own risks. Side effects often get buried under professional jargon, but for anyone taking Mellocillin Sodium, knowing what to expect can help spot trouble early and avoid bigger problems down the road.
During several years working alongside pharmacists in a hospital, I watched nurses keep a careful eye on patients starting intravenous antibiotics like Mellocillin Sodium. Complaints popped up pretty quickly in some cases. The most frequent? Stomach pain, diarrhea, or loose bowel movements. These gut disturbances often happen because antibiotics knock down both good and bad bacteria. Mild belly upset can come and go, but persistent or severe diarrhea always means a call to the doctor, given the risk of Clostridium difficile infection—an illness that can land people in the ICU.
Some folks report headaches and dizziness, which pass quickly in most cases. In my own run-in with a similar drug, I started getting flushed and noticed my heart beating faster, almost like I’d downed a few too many cups of coffee. For some, especially those getting long courses, changes in blood counts sneak up. Doctors run blood tests to catch problems like low white blood cells, a possible warning sign of bone marrow suppression.
Allergies deserve real respect with drugs like this. Having watched a patient’s face swell rapidly after just a few minutes, I’ll never forget the look of panic in their eyes—or the way the room moved when staff rushed for oxygen and adrenaline. Rashes, itching, swelling of the lips, or breathing problems need medical attention, no exceptions. Anyone with a penicillin or cephalosporin allergy faces bigger risk, since Mellocillin is part of the beta-lactam family of antibiotics.
Sometimes, odd reactions show up days or even weeks later. Drug-induced fever, swelling in the joints, or yellowing of the eyes can signal problems in the liver or kidneys. One study published in the Journal of Clinical Pharmacy reported that kidney injury showed up in patients with pre-existing kidney disease and those on higher doses. Those taking other medications that stress the kidneys, such as NSAIDs or diuretics, should let their care team know.
No medicine works in a vacuum. For anyone on Mellocillin Sodium, reporting symptoms—especially new rashes, breathing changes, or dark-colored urine—helps prevent emergencies. Medical teams often test blood and urine, especially in people who already live with chronic health problems, to catch damage before it spirals. Pharmacies carry oral probiotics, which can sometimes help settle stomach problems by restoring good bacteria, though these should only be started after talking with a doctor.
Doctors try to match the right antibiotic to the right bug, using the lowest effective dose for the shortest time. Regular updates between pharmacists, nurses, and patients keep things safer. For patients, good questions and honest reporting go further than silent worry. Trust built through shared facts can stop a setback before it robs someone of their recovery.
Mellocillin sodium gets prescribed for fighting off stubborn bacterial infections. It stands in the beta-lactam class, which means it works a bit like other penicillins. Plenty of doctors reach for it when they want something reliable against a nasty bug. Still, trust in antibiotics doesn’t mean they play well with every other medicine or medical condition. My experience with patients using antibiotics reminds me that even trusted medicines can surprise us, especially when new drugs get added to the mix.
A few meds run into trouble with mellocillin sodium. Allopurinol, for example, gets handed out a lot for gout. Mixed with penicillins like mellocillin, allopurinol often causes skin rashes. This isn’t just a red patch or two — the itching gets uncomfortable fast. If you see new symptoms pop up, contact your doctor quickly.
Diuretics cause another problem. These “water pills” for high blood pressure or swelling might sound harmless, but they shift the way your body handles sodium and potassium. Mellocillin sodium can raise the risk of damaging your kidneys when taken with diuretics like furosemide. If you live with heart or kidney issues, don’t ignore unexplained tiredness or swelling in the legs. Lab checks for kidney function never hurt either, just to be sure the meds aren’t pushing things too far.
Warfarin, that classic blood thinner, faces some interference from penicillins. The antibiotics may thin the blood just a bit more than wanted. Nosebleeds or blood in your urine mean you need to see a doctor—fast. Managing warfarin always means juggling your dose based on other medicines in your life.
Penicillin allergies destroy the benefit of mellocillin sodium. Even one round years ago with a bad reaction counts as a red flag today. Reactions range from hives to full-blown shock. Always alert your healthcare provider about past antibiotic trouble. Some folks also carry a higher risk for seizures when mixing beta-lactam antibiotics with seizure meds. If epilepsy’s already a struggle, let the doctor know before popping those pills.
People with kidney problems walk a finer line with antibiotics. Drugs like mellocillin sodium leave the body mostly by way of the kidneys. Poor kidney function lets the drug build up, leading to higher odds of nausea, confusion, or other side effects. Your doctor may want to tweak the dose or run a few extra blood tests.
Honest communication and up-to-date medication lists make the biggest difference. Double-check any supplement, herbal remedy, or over-the-counter medication you use before taking something new. Even something as common as calcium or iron pills can trip up medicines, sometimes reducing their effectiveness before you know it.
If you’re unsure about a drug combo, pharmacists have the training to spot red flags. A quick call can save a lot of stress and money, and possibly avoid a hospital stay. Simple as that.
References:Doctors choose Mellocillin Sodium to get rid of tough infections. People often hear about antibiotics for common ear or skin infections, but in the hospital, Mellocillin steps up for dangerous bacteria that ignore most pills. I remember sitting with friends in pharmacy school memorizing these doses, but in clinic, I realized guidelines help, yet every person brings their own history, their own risks, their own body weight.
Recommended dosing for adults often falls between 2 to 4 grams every 6 to 8 hours, given by injection or intravenous drip. According to Sanford Guide and the FDA label, this approach helps hit bacteria fast and keeps drug levels up. Sticking with these upper-end doses pushes back against stubborn bugs like Pseudomonas or Klebsiella. Doctors will review kidney function first, because injured kidneys hold onto drugs longer, and extra Mellocillin can harm the body instead of healing it. Overdosing with antibiotics doesn’t just hit the kidneys; brains can get foggy, and stomach problems pop up more often too.
Children break all the dosing rules. Age, size, and maturity of organs change how drugs behave. For kids, guidance usually starts around 100 mg per kilogram of body weight per day, split into several smaller doses. Higher doses sometimes come into play for very sick kids needing a quick turnaround, 200 to 300 mg/kg/day at times. It makes a real difference having pediatricians double-check calculations and adjust for children with kidney or liver quirks. Systems like the British National Formulary for Children lay out these ranges, and the American Academy of Pediatrics recommends always erring on the side of vigilance.
Missed doses can stir up a world of trouble, and skipping antibiotics when they’re needed doesn’t just threaten the patient—it fuels antibiotic resistance worldwide. Families should talk to their doctor, stick to the plan as best as possible, and alert the care team if a dose slips by. Most of us don’t think about antibiotic stewardship, but it's something that can touch every home—making sure these powerful medicines stick around for the next generation.
Quality dosing depends on clear communication. Doctors and pharmacists must check drug compatibility with other medicines, allergies, pregnancy status, and liver or kidney health. Lab tests help steer each step. In real life, patients forget doses, and side effects like nausea or diarrhea can tempt anyone to quit early. Nurses and families both play vital roles by flagging problems fast instead of letting them fester. Everyone benefits from updates in how labs identify and test resistant bacteria, so treatment stays a step ahead.
Real-world use requires flexibility. Guidelines set the outer boundaries, but getting it right means checking in, reassessing, and making changes if someone isn’t getting better fast enough. Some medical centers collect antibiotic use statistics to spot problems, educate teams, and root out mistakes before they grow.
Mellocillin Sodium isn’t something to grab off the shelf and guess. Dosages for adults and children both follow tested guidelines that weigh out science with safety and real-world experience. Still, families deserve to know why the strategy matters. Without trust and clear answers, mistakes only spread. Good medicine means patient questions never get brushed off—and clear instructions go out the door with every dose.
| Names | |
| Preferred IUPAC name | Sodium (2S,5R,6R)-6-[(2R)-2-[[(2-methoxyphenyl)acetyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Other names |
Mecilinam sodium Amidinocillin sodium |
| Pronunciation | /ˌmɛl.oʊˈsɪl.ɪn ˈsoʊ.di.əm/ |
| Identifiers | |
| CAS Number | 41136-22-5 |
| Beilstein Reference | 2216911 |
| ChEBI | CHEBI:131729 |
| ChEMBL | CHEMBL2106049 |
| ChemSpider | 22827635 |
| DrugBank | DB01329 |
| ECHA InfoCard | 100.220.273 |
| EC Number | 25988-97-0 |
| Gmelin Reference | 85958 |
| KEGG | C07448 |
| MeSH | D008574 |
| PubChem CID | 124006 |
| RTECS number | XJ86L6876A |
| UNII | N9638U1K73 |
| UN number | UN2814 |
| Properties | |
| Chemical formula | C20H23N3NaO7S |
| Molar mass | 1086.08 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.53 g/cm³ |
| Solubility in water | Freely soluble in water |
| log P | -2.4 |
| Acidity (pKa) | 12.82 |
| Basicity (pKb) | 2.64 |
| Magnetic susceptibility (χ) | Diamagnetic |
| Refractive index (nD) | 1.47 |
| Dipole moment | 2.72 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 321.1 J·mol⁻¹·K⁻¹ |
| Pharmacology | |
| ATC code | J01CA11 |
| Hazards | |
| Main hazards | May cause allergic reactions; hazardous in case of eye contact, ingestion, or inhalation. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | Keep away from sunlight", "Keep in a dry place", "Do not store above 25°C", "For intravenous use", "Prescription only |
| Signal word | Warning |
| Hazard statements | No hazard statements. |
| Precautionary statements | Store in a dry, well-ventilated place below 25°C. Keep out of reach of children. Avoid exposure to direct sunlight. For use by qualified personnel only. |
| NFPA 704 (fire diamond) | 2-1-0 |
| Lethal dose or concentration | LD50 (intravenous, mouse): 8000 mg/kg |
| LD50 (median dose) | LD50: 8000 mg/kg (intravenous, mouse) |
| NIOSH | Not Listed |
| PEL (Permissible) | 100 mg/m³ |
| REL (Recommended) | 60–150 mg/kg/day |
| Related compounds | |
| Related compounds |
Amidinocillin Hetacillin Mecillinam |