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Product Name: Meglumine
Chemical Name: N-Methyl-D-glucamine
Synonyms: 1-Deoxy-1-(methylamino)-D-glucitol, Methylglucamine
CAS Number: 6284-40-8
Recommended Use: Used as a pharmaceutical excipient, buffer, and intermediate in synthesis
Manufacturer: Pharmaceutical or chemical provider's information required to fill
Emergency Phone: Local emergency numbers and corporate emergency contact details supplied under incident reporting protocol
Classification: Non-flammable solid, not classified as hazardous under GHS
Health Hazards: Direct contact may cause mild irritation to skin, eyes, and mucous membranes
Environmental Hazards: Not considered harmful to aquatic environments, suitable environmental management advised
Symbol/Pictogram: No GHS pictogram necessary
Signal Word: None
Hazard Statements: May cause slight discomfort to exposed tissues, particularly if inhaled in significant concentration
Precautionary Statements: Prevent unnecessary exposure, avoid inhalation and contact with eyes
Chemical Identity: N-Methyl-D-glucamine
CAS Registry Number: 6284-40-8
EC Number: 228-509-3
Formula: C7H17NO5
Purity: Typically ≥99%
Impurities: Trace water, process-related residuals dependent on supplier specifications
Inhalation: Move individual to fresh air immediately, seek medical attention if symptoms like coughing or breathing discomfort persist
Skin Contact: Wash affected skin with copious amounts of soap and plenty of water, remove any contaminated clothing
Eye Contact: Flush eyes, holding eyelids apart under gentle running water for at least 15 minutes, consult a health specialist if irritation remains
Ingestion: Rinse mouth with water, never induce vomiting, consult a doctor immediately for guidance
Symptoms: Potential for redness or discomfort at point of contact, rarely serious unless exposure is high or prolonged
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, or foam depending on surrounding fire
Specific Hazards: Does not ignite readily; combustion can produce carbon oxides, nitrogen oxides
Protective Equipment: Wear protective gear including self-contained breathing apparatus to prevent inhalation of fumes
Fire-Fighting Procedures: Avoid direct contact with the substance, ensure ventilation, keep containers cool by spraying with water
Personal Precautions: Avoid dust generation, wear appropriate PPE (gloves, safety goggles, dust mask if ventilation poor)
Environmental Precautions: Prevent run-off into drains and surface waters, contain spill using noncombustible absorbents like sand or dust mop
Clean-Up Methods: Collect powder mechanically, transfer to clearly labeled waste container, wash spill site with soap and water
Disposal: Handle collected material in accordance with local regulations and facility protocols
Handling: Use in well-ventilated areas only, avoid inhaling dust, handle with gloves and eye protection
Storage Conditions: Store in original, tightly closed containers away from direct sunlight, moisture, acids, and incompatible materials
Special Sensitivities: Avoid excessive heat, freezing, and exposure to airborne contaminants
Incompatibilities: Strong acids, oxidizers, certain reactive metals
Engineering Controls: Use local exhaust ventilation to minimize airborne particles
Personal Protective Equipment: Chemical-resistant gloves, tightly fitting safety goggles, laboratory coat, dust mask where dust is generated
Hygiene Measures: Wash hands thoroughly throughout and after use, remove contaminated clothing, do not eat, drink, or smoke in work area
Exposure Limits: No established Occupational Exposure Limits listed in ACGIH or OSHA for meglumine
Appearance: White crystalline powder
Odor: Odorless
Odor threshold: Not applicable
pH Value: Aqueous solutions range 9.5–11.0 (typically measured at 10% solution)
Melting Point/Freezing Point: 128–132°C
Boiling Point: Decomposes before reaching a boiling point
Flash point: Not applicable
Evaporation rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible
Density: Approximately 1.37 g/cm³
Solubility: Soluble in water, slightly soluble in ethanol
Partition coefficient (n-octanol/water): Not determined
Auto-ignition temperature: No data available
Decomposition temperature: >130°C
Viscosity: Not applicable
Chemical Stability: Stable under normal handling and storage conditions
Possibility of Hazardous Reactions: No dangerous reactions if used as intended, avoid mixing with strong acids and oxidizers
Conditions to Avoid: Moisture, extreme heat, open flames, strong acids or oxidizing materials
Hazardous Decomposition Products: May generate carbon monoxide, carbon dioxide, nitrogen oxides under intense fire
Incompatible Materials: Strong oxidizers, acids, reactive metals like sodium or potassium
Acute Toxicity: LD50 (oral, rat) >15,800 mg/kg, essentially low acute toxicity
Skin Corrosion/Irritation: Mild, non-corrosive
Eye Damage/Irritation: Mildly irritating for sensitive individuals only
Sensitization: Not classified as sensitizer
Mutagenicity/Carcinogenicity: No reliable evidence of mutagenic or carcinogenic effects in published scientific data
Chronic Effects: Repeated exposure not likely to cause significant harm
Potential Routes of Exposure: Ingestion, inhalation, dermal, ocular
Ecotoxicity: Low toxicity expected for aquatic and terrestrial ecosystems
Persistence and Degradability: Likely biodegradable under most environmental conditions
Bioaccumulation Potential: Low, based on water solubility and molecular structure
Mobility in Soil: High water solubility suggests substance disperses rapidly through soil
Other Hazards: No specific data identify long-term environmental threats during normal use
Waste Treatment Methods: Dispose as non-hazardous chemical waste, following all regulations under local, regional, or national authority
Unused Product: Send to licensed disposal facility after consultation with authorities, label contents accurately
Contaminated Packaging: Triple rinse and dispose or recycle containers in alignment with official guidance
Recommendation: Avoid disposal into sewer systems or natural waterways
UN Number: Not applicable
UN Proper Shipping Name: Not regulated as hazardous for transport
Transport Hazard Class: Not classified
Packing Group: Not assigned
Special Precautions: Shield from excess moisture and avoid package breakage
Environmental Hazards: None identified
Inventory Listings: Listed in relevant major chemical inventories (TSCA, REACH, EINECS, DSL)
SARA Title III (Sections 302, 313): Not regulated
California Proposition 65: Not listed
WHMIS Classification: Not governed as controlled substance
OSHA Status: Not hazardous
Labeling: Standard laboratory/chemical labeling recommended, keeping user safety at the forefront
Other Regulations: Follow all workplace and environmental protection rules as defined in your region
