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Chemical Name: M-Toluidine
Common Names: 3-Aminotoluene, meta-Toluidine
CAS Number: 108-44-1
Appearance: A colorless to pale yellow liquid with a strong, amine-like odor
Primary Uses: Dye manufacturing, chemical synthesis for pharmaceuticals and pesticides, lab reagents
Health Hazards: Toxic if swallowed, inhaled, or absorbed through skin; dangerous for liver, kidneys, hematopoietic system
Acute Risks: Can cause methemoglobinemia, headaches, dizziness, blue skin tips, weakness, rapid pulse
Chronic Exposure: Prolonged contact can lead to organ damage and increased cancer risk
Flammability: Classified as a Combustible Liquid
Environmental Hazards: Toxic to aquatic life; spills cause lasting environmental damage
Active Substance: M-Toluidine concentration ranges above 99% in pure samples
Impurities: Trace levels of related toluidine isomers and minor residuals from synthesis
Inhalation: Shift to fresh air at once; offer oxygen if breathing becomes difficult; seek immediate medical attention
Skin Contact: Wash skin thoroughly using soap and water; remove contaminated clothing
Eye Contact: Rinse with water for at least 15 minutes; eyelids open throughout; seek medical help without delay
Ingestion: Do not induce vomiting; rinse mouth; seek trained medical care right away
Important Symptoms: Shortness of breath, confusion, blue lips or fingers signal critical effects
Suitable Extinguishing Media: Use foam, dry chemical powder, or carbon dioxide; avoid water spray, since runoff may contaminate
Fire Hazards: Toxic fumes like nitrogen oxides, carbon monoxide may form in a fire
Protective Equipment: Firefighters need full chemical protective gear and self-contained breathing apparatus
Special Procedures: Cool exposed containers with water mist from safe distance to keep the product from rupturing
Personal Safety: Evacuate area, ventilate properly, keep sources of ignition away; wear chemical protective clothing
Environmental Management: Block entry to drains and water sources; absorb spill with inert material like sand or vermiculite
Clean Up: Collect absorbed material into sealed chemical waste containers; wash contaminated surfaces well
Handling: Keep containers tightly sealed; avoid direct contact with skin and eyes; work under fume hood, use proper ventilation
Storage: Store in cool, dry, well-ventilated rooms; keep away from direct sunlight, ignition sources, and incompatible materials such as strong oxidizers or acids
Incompatibilities: Strong acids, oxidizing agents may set off hazardous reactions
Engineering Controls: Use local exhaust ventilation, safety enclosures, and closed handling systems wherever possible
Personal Protection: Wear chemical-resistant gloves (such as nitrile), tight-fitting safety goggles, lab coats or impervious clothing, and approved respiratory masks if vapor exposure cannot be avoided
Hygiene Measures: Wash hands and face thoroughly right after handling; never eat, drink, or smoke in the lab or storage areas
Workplace Monitoring: Regular air quality monitoring determines if fumes stay below recommended limits
State: Liquid at room temperature
Color: Ranges from colorless to pale yellow
Odor: Powerful amine or aromatic smell
Boiling Point: About 200°C
Melting Point: -30°C
Vapor Pressure: Low, meaning minimal evaporation at ambient temperatures
Solubility: Slightly soluble in water, more soluble in organic solvents like ethanol, ether
Flash Point: Approximately 85°C
Chemical Stability: Remains stable in proper storage when shielded from light, heat, and air
Incompatible Materials: Acids, strong oxidizers, reactive halogens
Decomposition Products: Burns form carbon monoxide, nitrogen oxides, sometimes aniline derivatives
Polymerization: No dangerous polymerization expected under normal conditions
Routes of Exposure: Entry through skin, inhaled vapors, accidental ingestion
Acute Toxicity: Ingesting or breathing small amounts leads to nausea, headache, confusion, cyanosis
Skin Effects: Prolonged or repeated contact brings irritation, possible allergic dermatitis
Delayed Effects: Abuse or repeated low-level exposure believed to increase liver and kidney risks; meta-toluidine belongs to a chemical class flagged for potential cancer risk
Aquatic Toxicity: Even moderate spills threaten fish and water insects; decomposition persists for weeks in freshwater
Persistence and Degradability: Does not break down quickly and may accumulate in soil and groundwater
Bioaccumulation: Moderate, some buildup possible in aquatic environments
Mobility: Liquid seeps into soils, risks ground and surface water contamination
Waste Treatment: Large volumes get incinerated in controlled facilities equipped with fume scrubbers
Container Disposal: Triple rinse, puncture, and send for licensed chemical recycling
Local Regulations: Follow national and municipal hazardous waste rules; improper disposal harms people and animals down the line
Regulated as: Hazardous material during national and international shipping
Transport Precautions: Label containers with toxicity and flammability markings; protect from mechanical shock
Packaging: Use UN-certified sealed drums or high-integrity glass bottles, secondary containment recommended
Spillage In Transit: Emergency response kits with absorbents and neutralizers accompany shipments
Classification: Labeled as toxic and dangerous for the environment under worldwide chemical safety laws
Permitted Limits: Strict workplace exposure limits set by OSHA and EU agencies, most list time-weighted averages in the low parts-per-million range
Restrictions: Use triggers extra record-keeping in several countries; waste disposal falls under hazardous waste codes
Right-To-Know: Employers must make health and safety data available to those who handle M-Toluidine
