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Product Name: Lycopene
Chemical Name: Lycopene
Chemical Formula: C40H56
CAS Number: 502-65-8
Molecular Weight: 536.85 g/mol
Synonyms: All-trans-Lycopene, E160d
Recommended Use: Food coloring, dietary supplement, antioxidant
Manufacturer Information: Detailed manufacturer contact, emergency phone, and address information must accompany bulk shipments or laboratory supplies for safety compliance.
Classification: Not classified as hazardous under GHS criteria
Physical Hazards: Fine dust may cause explosion in air under certain conditions
Health Risks: Inhalation of dust may cause mild respiratory irritation; eye contact can irritate; repeated skin contact rarely causes discomfort
Environmental Impact: Not expected to be hazardous for aquatic or terrestrial life in small quantities
Label Elements: No specific pictogram required. May use warning statements for eye and respiratory irritation if handling powdered forms.
Main Component: Lycopene
Concentration: Typically ≥90% by weight in purified form
Impurities: Trace amounts of other carotenoids (β-carotene, phytoene)
Type: Pure substance or extract, depending on supplier
Origin: Extracted from natural sources such as tomatoes, watermelons, or produced by chemical synthesis
Inhalation: Move person to fresh air, seek medical attention for persistent irritation
Skin Contact: Rinse with soap and plenty of water. Remove contaminated clothing
Eye Contact: Flush eyes cautiously with water for several minutes, remove contact lenses if present and easy to do, consult medical professional if irritation continues
Ingestion: Rinse mouth with water, drink water if feeling unwell, contact healthcare provider if large quantities consumed or discomfort persists
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray
Unsuitable Methods: Direct stream of water can distribute powder
Specific Hazards: Fine powder may ignite or explode in the presence of air and ignition source
Protective Equipment: Full fire-fighting gear and self-contained breathing apparatus
Decomposition Products: Produces carbon monoxide, carbon dioxide, and possible organic compounds when burned
Personal Precaution: Prevent dust accumulation; avoid inhalation or eye contact
Protective Equipment: Dust mask or respirator, safety goggles, gloves
Spill Response: Sweep or vacuum up without generating dust, transfer to secure container for disposal, ventilate area, clean spill surfaces
Environmental Protection: Prevent material from entering drains or water courses; gather residues for proper disposal.
Handling: Minimize dust generation and accumulation, use only in well-ventilated spaces, avoid contact with eyes and skin, use personal protection as needed
Storage Conditions: Store in tightly sealed containers, protect from heat, light, and moisture; keep away from sources of ignition, acids, and oxidizing materials
Special Recommendations: Keep refrigerating temperatures (2–8°C) for long-term storage, clearly label containers
Exposure Limits: No established limits by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation to control airborne dust, provide eye wash stations
Personal Protection: Use NIOSH-approved dust masks, chemical safety goggles, gloves, and lab coats
Hygiene Measures: Do not eat, drink, or smoke during handling, wash hands before breaks and at end of shift
Appearance: Red to reddish-purple crystalline powder
Odor: Practically odorless
Melting Point: 172–175°C
Boiling Point: Decomposes before boiling
Solubility: Insoluble in water, soluble in organic solvents (chloroform, dichloromethane, hexane)
pH: Not applicable
Flash Point: Not flammable as bulk solid, but finely divided powder may ignite
Vapor Pressure: Not relevant for solid
Density: Approximately 0.85–0.88 g/cm3
Partition Coefficient (n-octanol/water): Log P > 10
Autoignition Temperature: Data not available; handle powders carefully to avoid dust explosions
Stability: Stable under recommended storage and handling conditions
Sensitivity: Prone to oxidation, degrades rapidly in presence of light, heat, and oxygen
Reactivity: Reacts with strong oxidants and acids
Hazardous Decomposition: On burning, may emit hazardous gases such as carbon monoxide, carbon dioxide, unidentified organic compounds
Polymerization: Does not undergo hazardous polymerization
Acute Toxicity: Low; oral LD50 (rats) > 5000 mg/kg
Inhalation: Dust can cause irritation to respiratory tract
Skin Irritation: Uncommon; may cause mild irritation in sensitive individuals
Eye Irritation: Causes slight to moderate irritation
Sensitization: No known allergic reactions reported
Chronic Effects: Studies did not show significant risks for cancer, reproductive, or mutagenic effects; widely consumed in foods without known harm
Eco-toxicity: No evidence for acute or chronic harm to aquatic or terrestrial organisms at low concentrations
Mobility: Planted in soils, remains in upper layers due to low water solubility
Persistence and Degradability: Breaks down through photodegradation and biodegradation in the environment
Bioaccumulation: Not expected to accumulate in aquatic organisms
Other Effects: No recognized impact on wastewater treatment microflora
Waste Treatment: Manage lycopene-contaminated materials as non-hazardous under normal circumstances
Disposal Method: Dispose of in accordance with local, regional, and national regulations for non-hazardous organic waste
Avoid Release: Do not discharge significant quantities into surface water or sewers
Container Disposal: Decontaminate containers and recycle or dispose according to local requirements
UN Number: Not regulated
Proper Shipping Name: Lycopene
Hazard Class: Non-hazardous for ground, air, or sea transport
Packing Group: Not relevant
Transport Label: No hazard label required; bulk shipments must include package labeling to minimize dust and exposure risks
Special Precautions: Ship in cool, dry, well-sealed packaging to limit light and heat contact; avoid generating dust during loading and unloading
GHS Compliance: Not classified as hazardous under CLP Regulation (EC) No 1272/2008
OSHA Regulation: Not listed as hazardous by US OSHA Hazard Communication Standard 29 CFR 1910.1200
REACH Status: Exempted as a food ingredient and naturally occurring substance
FDA GRAS Status: Recognized as Generally Recognized As Safe (GRAS) for food use in the United States
Other Regulations: Listed and permitted as a natural colorant in food by European Food Safety Authority (EFSA) and related jurisdictions
