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Product Name: L-Tryptophan Food Grade
Chemical Name: L-α-Amino-3-indolepropionic acid
Synonyms: Tryptophan, Amino Acid Tryptophan
CAS Number: 73-22-3
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23 g/mol
Supplier: Food ingredient and chemical distributors, usually listed on packaging
Uses: Nutritional supplement, feed additive, pharmaceutical ingredient, dietary supplement
GHS Classification: Not classified as hazardous under GHS standards for food grade use
Signal Word: None required
Hazard Statements: No major hazards noted under normal use. Dust may cause mild eye, skin, or respiratory irritation.
Precautionary Statements: Avoid breathing dust, wear eye protection if dust levels become airborne, keep away from moisture
Appearance: White to off-white crystalline powder
Potential Health Effects: Contact may irritate eyes, nose, or skin. Not known to cause systemic health effects through ingestion when used in food.
Chemical: L-Tryptophan
Content: ≥98.5% by weight
Other Ingredients: None expected in food grade material. May contain trace moisture.
Inhalation: Move person to fresh air, seek medical attention if coughing or respiratory discomfort continues.
Skin Contact: Rinse with soap and water, remove contaminated clothing if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present, continue rinsing if irritation occurs.
Ingestion: If large amounts are swallowed and symptoms develop, seek medical attention. No routine hazard from food-grade doses.
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Specific Hazards: Fine dust may form explosive mixtures with air, though risk is low due to particle size
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear
Thermal Decomposition: May release carbon oxides, nitrogen oxides, and indole vapors if burned
Personal Precautions: Avoid breathing dust, use dust mask or respirator, ventilate area
Environmental Precautions: Prevent release to drains, surface water, or soil in large spills
Containment/Cleanup: Sweep up spills with minimal dust production, place in suitable containers, wash area with water after removal
Handling: Avoid dust generation, handle in dry, well-ventilated area, wash hands after use
Storage: Keep tightly sealed in original containers, store in a cool, dry, and well-ventilated place, protect from humidity and direct sunlight
Incompatibilities: Strong oxidizers, moisture, acids and bases in concentrated form
Occupational Exposure Limits: No official exposure limits for L-Tryptophan; use general dust limits (particulate not otherwise regulated)
Engineering Controls: Use process enclosures, local exhaust ventilation, or dust collection to keep levels below recommended exposure values
Eye Protection: Safety glasses or goggles if airborne dust increases
Skin Protection: Standard work clothing, gloves if prolonged/repeated contact
Respiratory Protection: Dust mask or respirator during dusty operations
Hygiene Measures: Wash hands before eating, drinking, or smoking at worksite
Appearance: White to off-white crystalline powder
Odor: Slight, characteristic
Odor Threshold: Not determined
pH (1% aqueous): 5.5–7.0
Melting Point: 289 °C (decomposition)
Boiling Point: Not applicable
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable in solid form
Explosive Properties: Dust explosion risk at high concentrations
Vapor Pressure: Not applicable
Solubility: Slightly soluble in water (11.4 g/L at 25°C)
Partition Coefficient: log Kow -1.06 (estimated)
Auto-ignition Temperature: Not readily auto-ignitable in normal conditions
Chemical Stability: Chemically stable under normal food storage conditions
Reactivity: Stable under recommended conditions, modifies with strong acids, bases, strong oxidizers
Conditions to Avoid: Keep away from excessive heat and moisture
Hazardous Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide, indole compounds
Polymerization: Not known to occur
Routes of Exposure: Eyes, skin, inhalation, ingestion
Acute Toxicity: LD50 (oral, rat) > 5,000 mg/kg
Chronic Effects: Not classified as carcinogenic, mutagenic, or teratogenic under current evidence
Inhalation: May irritate respiratory tract at high exposures
Skin: May cause mild, short-lived irritation
Eyes: May cause slight irritation on direct exposure
Ingestion: Toxicity is low, acts as an essential amino acid in regulated dietary use. Overdose in humans may cause drowsiness or digestive discomfort.
Ecotoxicity: Low acute toxicity to aquatic life, mainly due to rapid biodegradation
Persistence and Degradability: Quickly broken down by soil and water microbes
Bioaccumulation Potential: Not expected to bioaccumulate
Mobility in Soil: High mobility owing to water solubility
Other Adverse Effects: No evidence of environmental hazard at levels released from normal food or feed use
Waste Disposal Methods: Dispose of in accordance with local, state, and federal regulations. Material can often be disposed of as non-hazardous organic waste.
Contaminated Packaging: Rinse thoroughly before recycling or disposal
Precautions: Prevent from entering natural water bodies in significant quantities
UN Number: Not regulated for transport
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Protect from moisture and rough handling during transit; keep packaging intact to avoid contamination and spillage
Safety, Health, and Environmental Regulations: Meets food-grade standards as set by FDA (21 CFR 172.320), European Food Safety Authority, and most global regulators. Not listed on US TSCA inventory as a chemical needing special restrictions for food uses. Meets purity, labeling, and safety criteria in compliance with food and pharmaceutical standards.
Labelling Requirements: Product name, manufacturer information, batch number, and expiry date on packaging. Safety phrases typically not mandated for food grade, but best practice includes dust warnings.
Other International Compliance: Permitted as a food additive/amino acid supplement in line with Codex Alimentarius and JECFA recommendations.
