© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Isaconazole
Chemical Family: Azole antifungal
CAS Number: 241479-67-4
Use: Fungicidal agent in agriculture and pharmaceuticals
Manufacturer: Major chemical providers, producing for both industry and research environments
Emergency Contact: Refer to local regulatory authorities or poison control centers for region-specific emergency advice
SDS Number: Unique identifier specific to the manufacturer’s documentation system
Synonyms: (2RS,3RS)-3-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1-(1,2,4-triazol-1-yl)butan-2-ol
GHS Classification: Harmful if swallowed, causes serious eye irritation, possible skin irritation, possible reproductive toxicity
Signal Word: Warning
Hazard Statements: Toxic if inhaled or absorbed through skin, serious eye damage, harmful to aquatic life, may affect fertility
Pictogram: Exclamation mark, health hazard for chronic effects
Precautionary Statements: Avoid breathing dust, wear proper protective equipment, wash hands thoroughly after handling, avoid release into the environment
Acute Effects: Nausea, headache, irritation of eyes and skin
Chronic Effects: Liver effects in long-term exposure noted in animal studies, limited human data
Chemical Name: Isaconazole
Concentration: >98% in technical grade formulations for industry
Impurities: Trace solvents, inert carrier solvents, water (depending on preparation)
Other Ingredients: None present at hazardous levels, as verified by certificate of analysis by producer
Molecular Formula: C15H13Cl2N5O
Molecular Weight: 366.20
Inhalation: Move individual to fresh air, support breathing, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash affected area with plenty of soap and water, seek attention if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical help if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical assistance
Most Important Symptoms: Eye redness, skin rash or itching, temporary respiratory discomfort, digestive symptoms if ingested
Medical Attention and Special Treatment: Symptomatic and supportive care as indicated by medical professionals
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray for cooling containers
Unsuitable Extinguishing Media: Avoid strong water jets that might spread chemical
Hazardous Combustion Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide
Special Protective Equipment: Self-contained breathing apparatus and full protective clothing
Firefighting Advice: Move containers from fire area if safe, cool containers with water, avoid inhalation of fumes, wear chemical-resistant boots and gloves
Personal Precautions: Wear suitable protective gear including gloves, goggles, and respiratory protection
Environmental Precautions: Prevent entry to drains, sewers, and waterways, contain spill to avoid contamination
Methods for Clean-Up: Sweep or scoop spilled material into appropriate chemical waste containers, ventilate area, wash spill site thoroughly after material pickup is complete, dispose according to regulations
Special Instructions: Report incidents to safety supervisor, keep non-essential personnel away, minimize exposure by quickly containing the area
Handling: Use only in well-ventilated areas, avoid breathing dust or vapors, avoid direct skin and eye contact, employ safe chemical handling practices
Hygiene Measures: Wash hands thoroughly after handling, change contaminated clothing immediately, ensure eyewash stations and safety showers are accessible
Storage Conditions: Store in tightly closed original container, keep away from direct sunlight, incompatible substances, food or feed materials
Temperature Requirements: Store at controlled room temperature, avoid excess heat or freezing
Packaging Materials: Use containers resistant to organic solvents, avoid materials capable of reaction with azoles or strong oxidizers
Exposure Limits: No established permissible exposure limit, refer to manufacturer recommendations and any workplace site-specific standards
Engineering Controls: Use mechanical or local exhaust ventilation to minimize airborne concentrations
Personal Protective Equipment: Chemical-resistant gloves, splash-proof goggles, long-sleeve lab coat, respiratory protection if dust or vapor generated
Environmental Controls: Use spill control measures where risk of release exists, ensure operating procedures prevent contamination of water and soil
Monitoring Requirements: Monitor workplace air for dust or vapor, conduct regular safety audits for compliance with regulations
Appearance: White to off-white crystalline powder
Odor: Weak, slightly chemical
Odor Threshold: Not established
pH: No data for solid, pH of solutions varies by carrier
Melting Point/Freezing Point: 156–161 °C
Boiling Point: Decomposes before boiling
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: Not highly flammable, but dust formation may pose explosion hazard
Vapor Pressure: Very low at room temperature
Vapor Density: Not available
Relative Density: About 1.35–1.38
Solubility: Slightly soluble in water, reasonable solubility in dichloromethane, acetone
Partition Coefficient (log Kow): Approximately 4.0
Auto-ignition Temperature: Not specified
Decomposition Temperature: Above 220 °C
Viscosity: Not applicable for solid formulations
Chemical Stability: Relatively stable under recommended handling and storage conditions
Conditions to Avoid: High temperatures, direct sunlight, extreme humidity, strong oxidants
Incompatible Materials: Strong acids, strong bases, oxidizing agents, reducing agents
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon oxides, various organochlorine compounds
Possibility of Hazardous Reactions: No hazardous polymerization under normal conditions
Acute Toxicity: Oral LD50 (rat): 300–500 mg/kg, Dermal LD50 (rat): >2000 mg/kg, Inhalation LC50 (rat, 4h): >2.5 mg/L
Skin Corrosion/Irritation: Mild irritant in rabbits
Serious Eye Damage/Irritation: Causes irritation, risk of conjunctival redness and discomfort
Respiratory Sensitization: No experimental evidence of sensitization
Skin Sensitization: Not classified as skin sensitizer
Germ Cell Mutagenicity: No mutagenic effects recorded in standard assays
Carcinogenicity: No significant evidence from available long-term studies
Reproductive Toxicity: Adverse effects noted in high doses in animal studies, includes effects on fertility and fetal development
Specific Target Organ Toxicity: Repeated exposure can cause liver effects, but with limited evidence on human susceptibility
Aspiration Hazard: Not classified as aspiration risk
Ecotoxicity: Harmful to fish and aquatic invertebrates, moderate toxicity to some algae species
Persistence and Degradability: Moderately persistent in soil and water, incomplete degradation over short time
Bioaccumulative Potential: Moderate potential for bioaccumulation in aquatic organisms (log Kow ~4)
Mobility in Soil: Low water solubility and moderate soil adsorption reduce mobility
Other Adverse Effects: Long-term impact on microbial soil communities possible with repeated use
Environmental Precautions: Prevent access to sewers and natural waterways, use appropriate containment during field applications
Waste Treatment Methods: Incinerate under controlled conditions in accordance with local, regional, national regulations
Disposal of Product: Collect in tightly sealed containers, deliver to approved hazardous chemical disposal site
Disposal of Packaging: Triple rinse containers, puncture, and dispose as hazardous waste, never reuse for any other purpose
Other Recommendations: Follow specific regional and institutional protocols for hazardous chemical and pesticide disposal, maintain all records according to compliance guidelines
UN Number: Apply correct UN number based on regulatory agency listing for azole fungicides
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains Isaconazole)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: II or III depending on concentration and container size
Environmental Hazards: Classified as marine pollutant in bulk shipments
Special Precautions: Keep in approved packaging, clearly labeled, prevent release during transit, provide safety data sheet with shipment
Transport Regulations: Follow international agreements such as IMDG, IATA, ADR
TSCA: Listed, regulated under the Toxic Substances Control Act in the U.S.
REACH: Registration required for quantities exceeding specified thresholds in the EU
OSHA: Not specifically regulated, but controls required for hazardous chemical handling
SARA Title III: Subject to immediate notification in case of substantial accidental release
WHMIS (Canada): Controlled product, classified as hazardous
Other International Regulations: Subject to national pesticide legislation, specific reporting obligations for accidental losses, prohibited for some agricultural uses in sensitive regions
Labeling Requirements: Follow GHS/CLP standards, display hazard pictograms and warnings in local language, include reference to Safety Data Sheet
