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Material Safety Data Sheet: Ferulic Acid (Synthetic and Extraction)

Identification

Product Name: Ferulic Acid
Chemical Name: 4-Hydroxy-3-methoxycinnamic acid
Chemical Formula: C10H10O4
CAS Number: 1135-24-6
Relevant Identified Uses: Used as an antioxidant in industrial, research, and cosmetic applications
Manufacturer Information: Company name (address, phone, email, emergency contact included here)

Hazard Identification

Hazard Classification: Eye irritation category 2A, skin irritation category 2
GHS Label Elements: Exclamation mark symbol
Signal Word: Warning
Hazard Statements: Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Use personal protective equipment. Wash hands after handling.

Composition / Information on Ingredients

Chemical Identity: Ferulic Acid
Common Name: 4-Hydroxy-3-methoxycinnamic acid
Impurities and Stabilizing Additives: Typically pure, but may contain trace organic solvent residues from extraction
Concentration: Usually above 98% in synthetic and extract-derived ferulic acid

First Aid Measures

Inhalation: Move person to fresh air. Seek medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of water. Seek medical attention if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and seek medical advice.
Ingestion: Rinse mouth. Do not induce vomiting. Contact a physician or poison control center if you feel unwell.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Specific Hazards: Combustion generates toxic fumes of carbon oxides
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Special Instructions: Cool drums with water spray to prevent rupture due to heat

Accidental Release Measures

Personal Precautions: Use personal protection as indicated in Section 8
Environmental Precautions: Prevent spill from entering drains, sewers, or water sources
Methods for Cleanup: Collect spill using non-combustible absorbent, place in chemical waste container
Other Information: Ventilate area and wash spill site after material pickup is complete

Handling and Storage

Precautions for Safe Handling: Minimize generation of dust, avoid breathing vapors, use local exhaust ventilation
Conditions for Safe Storage: Keep container tightly closed, store in cool, dry, well-ventilated area, protect from light and incompatible substances
Incompatibilities: Strong oxidizers, acids, bases
Special Handling Notes: Keep away from open flames and heat sources

Exposure Controls and Personal Protection

Control Parameters: No occupational exposure limits established
Engineering Controls: Use fume hood or proper ventilation
Personal Protective Equipment: Safety glasses with side-shields, chemical-resistant gloves, lab coat, respiratory protection if dust or aerosols are present
Hygiene Measures: Wash hands and face thoroughly after handling materials, avoid eating or drinking in working area

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Faint, characteristic
Odor Threshold: Data not available
pH: Slightly acidic in aqueous solution
Melting Point: 172-174°C
Boiling Point: Decomposes before boiling
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: Not classified as flammable but may burn if heated
Vapor Pressure: Negligible
Vapor Density: Not applicable
Solubility: Slightly soluble in water, soluble in ethanol and methanol
Partition Coefficient (Log Kow): 1.5 (estimated)
Auto-Ignition Temperature: Not determined
Decomposition Temperature: Data not available
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Conditions to Avoid: Excessive heat, light, moisture, incompatible chemicals
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other hazardous fumes under fire conditions
Polymerization: Has not been reported to occur

Toxicological Information

Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg; not acutely toxic by inhalation or dermal routes in animal studies
Skin Corrosion/Irritation: May cause irritation
Serious Eye Damage/Irritation: Causes eye irritation
Respiratory or Skin Sensitization: No sensitization reported
Carcinogenicity: No classification for carcinogenicity by NTP, IARC, or OSHA
Reproductive Toxicity: No adverse effects in animal reproductive studies
Other Toxicological Effects: No mutagenic, teratogenic, or specific organ toxicity noted in available studies

Ecological Information

Ecotoxicity: Low acute aquatic toxicity; LC50 (fish): >100 mg/L, EC50 (daphnia): >100 mg/L
Persistence and Degradability: Expected to biodegrade in the environment
Bioaccumulative Potential: Low, based on log Kow
Mobility in Soil: Expected moderate mobility due to solubility
Other Information: Not listed as hazardous to the environment by regulatory agencies

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, state, and federal regulations; contact licensed waste disposal contractor
Contaminated Packaging: Handle each container in compliance with regulations; rinse before recycling or dispose as hazardous waste
Sewage Disposal Restrictions: Avoid release to sewers or natural waterways
Special Precautions: Consider chemical and physical properties before selecting disposal method

Transport Information

UN Number: Not classified as dangerous for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Advisories: Transport in tightly sealed containers; protect against physical damage and moisture

Regulatory Information

OSHA Status: Not listed as hazardous
TSCA Inventory: Listed
SARA Title III: Not listed as an extremely hazardous substance
California Proposition 65: Not listed
REACH Registration: Meets registration requirements for import to the EU
Other Regulatory Listings: None reported as of latest update