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Product Name: Faropenem Sodium
Chemical Name: (5R,6S)-6-[(R)-1-Hydroxyethyl]-7-oxo-3-[(E)-2-oxo-2-(2-thienyl)ethenyl]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, sodium salt
CAS Number: 122547-11-3
Molecular Formula: C12H13N2NaO5S2
Molecular Weight: 368.36 g/mol
Recommended Use: Pharmaceutical intermediate, research use
Supplier Details: Detailed manufacturer contact for emergencies, shipment, and handling
Emergency Phone Number: Global chemical emergency hotline included by supplier
GHS Classification: Causes serious eye irritation, respiratory system irritation, skin sensitization possible
Label Elements: Exclamation mark symbol, warnings about skin and eye contact
Hazard Statements: May trigger allergy or asthma symptoms, avoid breathing dust or powder
Precautionary Statements: Use personal protection, wash hands thoroughly after handling, avoid direct contact
Acute Effects: Redness, itching, swelling, irritation of respiratory and digestive tract
Chronic Effects: Possible long-term hypersensitivity, repeated exposure can produce allergies
Main Ingredient: Faropenem Sodium
Concentration: Greater than or equal to 95% pure
Impurities: Trace organic solvents, uninvolved reaction byproducts under 2%
Additives: None known relevant to normal use
Chemical Family: Beta-lactam antibiotics, penem subclass
Inhalation: Take person to fresh air immediately, keep comfortable for breathing, seek medical help
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water and soap for at least 15 minutes
Eye Contact: Rinse cautiously with plenty of water for 15 minutes, lift eyelids occasionally, get prompt medical attention
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical staff, consult poison control or physician
Most Important Symptoms: Allergic reactions like rash, tightness of chest, trouble breathing, irritation of eyes, nose, mouth
Notes for Physicians: Persistent symptoms deserve specialized allergy treatment, administer oxygen if required
Suitable Extinguishing Media: Use dry chemical powder, foam, or carbon dioxide for small fires; use water spray for larger fires
Unsuitable Extinguishing Media: Avoid high pressurized water jets that spread dust
Hazardous Combustion Products: Releases nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide, and possibly hydrogen sulfide
Special Equipment: Wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Keep containers cool, evacuate area if unsafe conditions, avoid inhaling thermal decomposition gases
Personal Precautions: Use chemical safety goggles, gloves, and appropriate respiratory protection, avoid dust formation
Environmental Precautions: Prevent further leakage or spillage if safe to do; stop from entering drains or waterways
Methods for Containment: Collect spill with inert absorbent material, sweep or vacuum to minimize airborne dust
Cleanup Procedures: Collect and place in closed, labeled containers for disposal as hazardous waste, ventilate area after cleanup
Decontamination: Wash area thoroughly with water after collection, ventilate until all residues are gone
Precautions for Safe Handling: Operate in well-ventilated locations, use proper industrial hygiene, keep away from food and drink
Contact Avoidance: Avoid eye, skin, clothing, and mucous membrane contact, handle in dedicated laboratory gear only
Storage Conditions: Store in cool, dry, well-ventilated place, away from incompatible materials such as acids, oxidizers
Container Materials: Use tightly closed, corrosion resistant packaging
Specific Use Directions: Store away from sunlight, moisture, strong temperature fluctuations; keep in original containers whenever possible
Engineering Controls: Use local exhaust ventilation, chemical fume hood preferred for powder handling
Occupational Exposure Limits: No specific exposure limit provided by OSHA or ACGIH for this compound
Protective Equipment: Chemical-resistant gloves (nitrile preferred), safety goggles, lab coat
Respiratory Protection: Suitable particulate respirator or NIOSH-approved masks in case of dust formation
Hygiene Measures: Wash hands after handling, do not eat or drink in work area, avoid touching face during use, remove contaminated clothing after exposure
Appearance: White to slightly off-white crystalline or powder
Odor: Odorless
Melting Point: Approximately 200–210 °C (decomposition starts above 210 °C)
Boiling Point: Not applicable (decomposes)
pH (1% solution): Around 7.0 to 8.5
Solubility: Freely soluble in water, slightly soluble in ethanol, insoluble in chloroform and ether
Vapor Pressure: Not measurable at standard room temperatures
Partition Coefficient (log Kow): Data not available
Other Data: Stable under recommended storage, not volatile under normal conditions
Chemical Stability: Stable if stored under recommended conditions (sealed, away from light and humidity)
Decomposition: May decompose on exposure to moisture, acids, strong bases, or elevated temperatures
Incompatible Materials: Strong oxidizers, strong acids, reducing agents, some metals (copper, zinc)
Hazardous Reactions: Hazardous polymerization not expected under normal use; releases hazardous gases if heated
Conditions to Avoid: Heat, flame, open spark, strong light, contact with chemicals above
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides observed during severe decomposition
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Oral LD50 (rat) above 2000 mg/kg (low acute toxicity)
Irritation: Eyes and skin may get irritated with direct contact; respiratory irritation likely for dust
Sensitization: Possible skin or respiratory allergen in repeated exposure users
Carcinogenicity, Mutagenicity, and Reproductive Toxicity: No human carcinogenesis or mutagenicity evidence in current studies, none listed by NTP, IARC, OSHA
Other Effects: May aggravate pre-existing skin or respiratory medical conditions
Ecotoxicity: Acute aquatic toxicity potential due to antibiotic activity, avoid uncontrolled release
Persistence and Degradability: Biodegradability not thoroughly established, antibiotics tend to persist in some environments
Bioaccumulation: Not expected to appreciably bioaccumulate in aquatic organisms
Mobility in Soil: Water solubility means fairly mobile in surface/groundwater
Other Adverse Effects: Could harm microbial populations in sewage and soil, take care during disposal or spills
Waste Disposal Methods: Treat as hazardous waste, incinerate under controlled conditions if possible, or dispose with licensed chemical waste contractor
Contaminated Packaging: Decontaminate reusable packaging where possible, otherwise treat as hazardous waste
Precautions: Do not flush down drain, avoid contaminating surface water, groundwater
Regulatory Compliance: Follow national, regional, and local environmental waste regulations; consult official codes before discarding
UN Number: Not regulated under most international transport codes
Proper Shipping Name: Chemical, non-regulated or as specified by carrier/country
Transport Hazard Class: Not classified under dangerous goods for transport
Packing Group: None assigned
Special Precautions: Avoid carriage with incompatible chemicals, use leak-proof, clearly labeled containers, keep documentation accessible
Labelling Requirements: GHS-compliant labels for hazard communication
OSHA Status: Not specifically regulated as hazardous under OSHA; observe standard laboratory safety practice
TSCA Status: Not listed in the US TSCA inventory as a commercial chemical
EINECS/ELINCS: Not registered or assigned in EU chemical lists
Other Regulations: Handle under applicable pharmaceutical or research chemical regulations, pharma-grade handling mainly guided by Good Manufacturing Practice (GMP)
Drug Regulatory Status: Controlled under multiple pharmaceutical regulatory authorities for medical uses only, research and clinical settings
Other Safety Data Requirements: Safety information must be updated as new research and regulatory guidance are issued
