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Chemical Name: Ethylene Glycol Ethyl Ether
Common Names: 2-Ethoxyethanol
CAS Number: 110-80-5
Use: Used in coatings, cleaning fluids, inks, and as a solvent in many industrial applications.
Physical State: Colorless liquid with a mild, pleasant odor.
Health Hazards: Inhalation or skin absorption can affect the central nervous system, blood, kidneys, and reproductive system.
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed, inhaled, or absorbed through skin. Risk of serious damage to health on prolonged exposure.
Signal Words: Danger
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Symptoms: Headache, nausea, dizziness, weakness, and possible unconsciousness; extended exposure may affect blood or organs.
Main Ingredient: Ethylene Glycol Ethyl Ether (2-Ethoxyethanol) at concentration above 98%
Impurities: May contain trace levels of related glycol ethers
Inhalation: Move person to fresh air, keep warm, and seek urgent medical attention if symptoms develop or persist.
Skin Contact: Remove contaminated clothing, wash affected skin thoroughly with soap and water, monitor for continued irritation.
Eye Contact: Flush eyes with water for at least 15 minutes, keep eyelids open, seek medical help if irritation or vision changes persist.
Ingestion: Rinse mouth with water, do not induce vomiting, and get immediate medical attention; risk of organ toxicity increases with dose.
Suitable Extinguishers: Dry chemical, carbon dioxide, alcohol-resistant foam
Fire Hazards: Vapors can travel to ignition source and flash back, liquid is flammable
Combustion Products: May release carbon monoxide, carbon dioxide, and potentially irritating fumes.
Advice for Firefighters: Use self-contained breathing apparatus; wear full protective gear in confined spaces.
Personal Precautions: Evacuate area, ventilate space, eliminate ignition sources, use personal protective equipment.
Spill Cleanup: Absorb with appropriate material (sand, earth, or inert absorbents), collect in suitable container for disposal.
Environmental Precautions: Prevent further leakage or spillage if safe to do so; avoid discharge into drains, watercourses, or soil.
Handling Practices: Work in well-ventilated areas, avoid inhalation of vapors, protect skin and eyes, prevent formation of aerosols.
Storage Conditions: Keep container tightly closed in a cool, dry, and well-ventilated place away from sources of ignition; segregate from oxidizers.
Hygiene: Wash hands thoroughly after handling; do not eat, drink, or smoke in work areas.
Occupational Exposure Limits: OSHA Permissible Exposure Limit: 5 ppm; ACGIH Threshold Limit Value: 5 ppm (skin)
Engineering Controls: Local exhaust ventilation, process enclosure, handling in chemical fume hoods
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, impervious clothing, respiratory protection if exposures are above limits
General Safety: Safety showers and eye wash stations should be accessible in work areas
Appearance: Clear liquid
Odor: Mild, ether-like
Boiling Point: Approximately 135°C (275°F)
Melting Point: -90°C (-130°F)
Flash Point: 43°C (109°F), closed cup
Vapor Pressure: 6 mmHg at 20°C
Solubility: Miscible with water and most organic solvents
Density: About 0.93 g/cm³ at 20°C
Chemical Stability: Stable under normal conditions
Risk of Hazardous Reactions: Can react with strong oxidizing agents, acids, acetic anhydride, and alkali metals
Decomposition Products: Thermal decomposition may produce hazardous fumes including carbon monoxide and carbon dioxide
Acute Toxicity: LD50 oral (rat) is about 2000 mg/kg; can be harmful by inhalation, ingestion, or absorption through the skin.
Chronic Toxicity: Prolonged or repeated exposure can result in serious effects on the blood, kidneys, nervous system, and reproductive system.
Sensitization: Not classified as a sensitizer, but skin and eye irritation can occur.
Carcinogenicity: Not classified as a human carcinogen, but some glycol ethers have been linked to adverse reproductive effects.
Mutagenicity and Teratogenicity: Animal studies show potential developmental toxicity.
Environmental Impact: Toxic to aquatic organisms at higher concentrations, risk of long-term effects in aquatic environments.
Persistence and Degradability: Readily biodegradable but may persist under certain conditions.
Bioaccumulation Potential: Low, but monitoring recommended near sensitive water bodies.
Mobility: High mobility in soil and water, which can increase risk to groundwater if not contained.
Disposal Methods: Treat as hazardous waste, comply with federal, state, and local regulations.
Waste Precautions: Do not dispose into drains or general waste streams; incineration in approved facilities is a common practice.
Packaging: Contaminated containers must be disposed of in the same way as the product.
UN Number: 1171
Shipping Name: Ethylene Glycol Monoethyl Ether
Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labeling: Flammable liquid label required for all transport containers.
Global Inventories: Listed in major chemical inventories such as TSCA (US), EINECS (EU), DSL (Canada), and others.
Workplace Regulation: Strict exposure limits, use of engineering controls and PPE mandated in occupational settings.
Restrictions: Some regions restrict use in consumer products due to reproductive and developmental effects.
Environmental Regulations: Spills and releases may need to be reported according to federal or state laws.
