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Material Safety Data Sheet (MSDS) – Diaveridine

Identification

Product Name: Diaveridine
Synonyms: 4,6-Diamino-2,4-pyrimidinediamine, N1-(2,4-diaminopyrimidin-5-yl)benzenesulfonamide
Chemical Formula: C13H16N4O2
CAS Number: 5355-16-8
Recommended Use: Antibacterial agent, often for veterinary use
Manufacturer Information: Check safety data from supplier. Contact manufacturer in event of emergency or if further hazard clarification is required.
Emergency Phone: Available through poison control or emergency services.

Hazard Identification

Classification: Harmful if swallowed, irritant to skin and eyes
Label Elements: Hazard pictograms (GHS07, Exclamation mark)
Signal Word: Warning
Hazard Statements: Causes mild to moderate skin and eye irritation; respiratory irritation following dust inhalation; may provoke allergic reactions; harmful if ingested in quantity
Precautionary Statements: Avoid contact with eyes and skin, avoid dust inhalation, wear protective gloves and eyewear, do not eat, drink, or smoke while handling, wash exposed skin thoroughly after use
Potential Health Effects: Short-term exposure may produce redness, itching, or coughing; longer exposure can aggravate existing respiratory or allergic conditions.

Composition / Information on Ingredients

Chemical Name: Diaveridine
Purity: Ranges from 95–99% typical
Impurities: Small residual synthesis byproducts possible
Other Components: May include trace moisture or stabilizing agents under 1% by formula weight
Mixture: Not applicable, product supplied as pure substance for main ingredient; secondary compounds minimal and typically proprietary.

First Aid Measures

Inhalation: Move individual to fresh air, consult medical professional if irritation or symptoms persist or worsen
Skin Contact: Wash affected area with soap and water for several minutes, remove contaminated clothing, seek attention for persistent irritation
Eye Contact: Rinse with gentle, copious water stream for at least 15 minutes, keep eyes wide open, obtain medical attention for persistent redness or discomfort
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical care if large amount ingested or symptoms appear
Medical Notes: Symptomatic treatment recommended; present product label or this sheet to a physician.

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, or water spray based on surrounding materials
Unsuitable Media: Direct, high-pressure water jet
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides, carbon monoxide, and other unknown gases
Protective Equipment: Full protective clothing, self-contained breathing apparatus recommended for all fire scenarios
Firefighting Guidance: Isolate hazard area, remove any unprotected individuals, prevent runoff from entering drains or watercourses.

Accidental Release Measures

Personal Precautions: Avoid inhaling dust, contact with skin or eyes; ventilate area; restrict access to spill area
Protective Equipment: Gloves, chemical-resistant apron, safety goggles or face shield, particulate mask (N95 or better)
Environmental Precautions: Prevent release into soil, drains, surface or groundwater
Clean-up Methods: Scoop or sweep solid gently, avoid dust generation, place in suitable container for disposal, decontaminate area thoroughly
Waste Disposal: Follow local, regional, and national regulations for hazardous waste, consult licensed waste disposal contractor.

Handling and Storage

Handling: Employ local exhaust or general room ventilation, avoid generation of dust and static discharge, wash after handling, keep containers tightly closed when not in use
Safe Storage: Store in a cool, dry, well-ventilated place away from direct sunlight, incompatible substances, food, and beverages
Storage Temperature: Recommended between 2–8°C for best long-term stability
Incompatibilities: Strong oxidizers, strong acids, strong bases; avoid moisture infiltration
Storage Containers: Use only tightly sealed original containers, proper secondary containment advised.

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood or local exhaust systems, handle only in areas with good airflow
Exposure Limits: No established occupational exposure limits; minimize exposure due to harmful potential
Respiratory Protection: NIOSH-approved particle mask or respirator for powders and dust
Skin Protection: Impervious gloves, protective laboratory coat
Eye Protection: Safety glasses with side shields, or face shield for larger quantities
Hygiene Measures: Do not eat, drink, or smoke during handling; wash hands before breaks and after final use.

Physical and Chemical Properties

Appearance: Light yellow to pale cream powder
Odor: Almost odorless or faint chemical scent
pH: 5–8 (1% solution in water)
Melting Point: 210–215°C
Boiling Point: Decomposes before boiling
Flashpoint: Not applicable (non-flammable under normal conditions)
Solubility: Slightly soluble in water, more soluble in dilute acids and alkali
Density: Around 1.35 g/cm³
Vapor Pressure: Negligible at ambient temperature
Viscosity: Not applicable for solid material
Partition Coefficient (log Kow): Data sparse, predicted low for environmental mobility.

Stability and Reactivity

Chemical Stability: Stable under normal handling, recommended storage conditions
Reactivity: Does not react dangerously with air, normal humidity, or light for short exposures
Decomposition Products: Fumes of NOx, COx, unknown sulfur and nitrogen products if strongly heated or burned
Polymerization: Not likely to occur
Incompatible Materials: Avoid contact with strong acids, bases, oxidizing agents; may trigger hazardous decomposition or react violently.

Toxicological Information

Acute Toxicity (LD50 in rats, oral): >2000 mg/kg (low acute toxicity by oral route based on animal studies)
Skin Corrosion/Irritation: Causes mild irritation, prolonged exposure may lead to dermatitis
Eye Damage/Irritation: Moderate eye irritation on contact
Sensitization: Sensitization possible in predisposed individuals
Chronic Exposure: Data limited; long-term overexposure may compromise blood or organ function in extreme cases due to sulfonamide group
Carcinogenicity/Mutagenicity/Teratogenicity: No data showing cancer or genetic mutation risk in typical handling use; always minimize unintended exposure.

Ecological Information

Ecotoxicity: Can be harmful to aquatic life with long lasting effects, especially in water environments with poor dilution or slow flow
Persistence/Degradability: Partial persistence possible; breaks down slowly in soil and water, may accumulate indirectly via sediment
Bioaccumulation: Bioaccumulation potential estimated low to moderate based on structural properties
Mobility: Not highly mobile in soil, but some leaching possible into surface or groundwater
Additional Hazards: Avoid uncontrolled release into waterways, monitor effluent from veterinary or pharmaceutical sites.

Disposal Considerations

Waste Method: Do not dispose down the drain or in household waste, treat as hazardous chemical
Recommended Disposal: Incineration in controlled facility, or landfilling by licensed chemical waste disposal company
Reuse/Recycle: Avoid reuse of contaminated containers, clean to regulatory standards if reclaiming
Local Support: Consult local waste authority or environmental agency for up-to-date guidance, supply MSDS to waste handlers.

Transport Information

UN Number: Not assigned for typical quantities
Transport Hazard Class: Not regulated as a dangerous good under most transport systems
Packing Group: None assigned
Special Precautions: Seal tightly, keep container upright, protect from physical damage, maintain separation from incompatible chemicals
Labeling: Indicate chemical name, hazard warnings, and emergency contact information on all packages.

Regulatory Information

OSHA Status: Not specially regulated by OSHA for workplace-specific standards
TSCA Inventory: May be listed on US Toxic Substances Control Act inventory; confirm for specific country regulations
EU/EINECS: Included in European inventory of existing commercial chemical substances
International Regulations: Consult national and regional regulatory lists for import, handling, and disposal; veterinary restrictions likely
Label Requirements: Follow Globally Harmonized System (GHS) for chemical labeling, update documents and signage for workplace transparency.