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Product Name: D-Biotin
Chemical Name: D-(+)-biotin
Synonyms: Vitamin H, Coenzyme R, W Factor, Bios II
CAS Number: 58-85-5
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.31 g/mol
Supplier: Contact authorized chemical supplier for specific company details
Recommended Use: Vitamin supplement, research applications
Restrictions: Not intended for food, drug, or household use except as regulated
GHS Classification: Substance not classified as hazardous under GHS criteria
Signal Word: None
Hazard Statements: Not expected to cause significant health hazards under normal handling; dust may cause mild respiratory irritation
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; avoid contact with eyes, skin, and clothing
Eye Contact: Possible mechanical irritation
Skin Contact: Unlikely to cause irritation in most cases
Substance Name: D-Biotin
Purity: ≥ 98%
Chemical Formula: C10H16N2O3S
CAS Number: 58-85-5
Other Ingredients: None reported
Impurities/Stabilizing Additives: Not applicable for pure compound
General Advice: Seek medical attention if symptoms develop or feel unwell
Inhalation: Move to fresh air; provide oxygen if breathing is difficult
Skin Contact: Wash with plenty of water and soap; remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do
Ingestion: Rinse mouth; do not induce vomiting unless directed by medical personnel; seek immediate medical attention if feeling unwell
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may spread powder
Hazardous Combustion Products: Emits toxic fumes under fire conditions including carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Special Firefighting Procedures: Prevent runoff from entering drains or waterways
Personal Precautions: Avoid dust formation; ventilate the area; use protective equipment
Environmental Precautions: Prevent material from entering sewage and drainage systems
Methods for Containment: Collect spillage to prevent dust scatter
Cleanup Methods: Sweep up and place in appropriate container; wash spill area with water
Disposal: Dispose of in compliance with local regulations
Handling: Handle in well-ventilated area; minimize dust generation; avoid contact with eyes, skin, and clothing
Hygiene Measures: Wash hands after handling; do not eat, drink, or smoke during use
Storage Conditions: Store in a cool, dry, and well-ventilated place; keep container tightly closed; protect from light and moisture
Storage Incompatibilities: Strong oxidizing agents
Recommended Packaging Materials: Use original containers or compatible materials
Occupational Exposure Limits: No specific exposure limits established
Engineering Controls: Use local exhaust ventilation to control airborne dust
Personal Protective Equipment (PPE):
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 5.0 – 8.0 (saturated solution)
Melting Point/Range: 232°C (450°F) decomp.
Boiling Point: Not applicable
Flash Point: Not applicable
Evaporation Rate: Not available
Flammability: Non-flammable
Vapor Pressure: Negligible at 25°C
Vapor Density: Not applicable
Relative Density: 1.5–1.6 g/cm³
Water Solubility: Slightly soluble (22 mg/L at 25°C)
Partition Coefficient (n-octanol/water): Log Kow: -0.11
Auto-Ignition Temperature: Not determined
Decomposition Temperature: >232°C
Viscosity: Not relevant for solid
Molecular Structure: Bicyclic monocarboxylic acid derivative containing sulfur and ureido ring
Chemical Stability: Stable under normal conditions of use and storage
Reactivity: Inert to most agents under standard storage
Conditions to Avoid: Heat, moisture, direct sunlight, incompatible chemicals
Materials to Avoid: Strong oxidizing agents
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: No hazardous polymerization expected
Acute Toxicity: Oral LD50 (rat) > 10,000 mg/kg; low toxicity observed
Description of Possible Health Effects: Inhalation of dust may cause slight respiratory irritation; contact with eyes may cause mild irritation; prolonged or repeated exposure not known to cause adverse effects
Skin Corrosion/Irritation: Not expected to cause significant irritation
Eye Damage/Irritation: Mechanical irritation possible
Respiratory or Skin Sensitization: Not expected to sensitize
Mutagenicity: No evidence found in available studies
Carcinogenicity: Not listed or suspected as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No adverse reproductive effects reported
Other Data: No known significant chronic effects
Aquatic Toxicity: Not regarded as hazardous for aquatic environments; low solubility and rapid biodegradability
Environmental Fate: Expected to be rapidly degraded by microorganisms in soil and water
Persistence/Degradability: Readily biodegradable
Bioaccumulative Potential: Low, based on log Kow
Mobility in Soil: Low due to low water solubility
Other Adverse Effects: Not expected to contribute to ozone depletion or global warming
Disposal Methods: Dispose of in accordance with national, regional, and local regulations; small quantities can enter ordinary waste if not prohibited
Contaminated Packaging: Dispose of as unused product unless thoroughly cleaned
Special Precautions: Prevent release into environment; consult local authorities for recommended disposal methods
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not regulated
Environmental Hazards: Not regarded as environmentally hazardous
Special Precautions: Keep container tightly sealed and protected from physical damage
Assigned Labels: None required
TSCA Status: Listed
REACH Status: Registered
OSHA Hazard Communication: Not hazardous
SARA 313: Not listed
California Proposition 65: Not listed
Canadian WHMIS Classification: Not controlled
Other Regulation: Follow all applicable international, national, and regional regulations
