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Material Safety Data Sheet: Cyanocobalamin

Identification

Product Name: Cyanocobalamin
Chemical Name: Cyanocobalamin
Synonyms: Vitamin B12, Cobalamin
CAS Number: 68-19-9
Recommended Use: Nutritional supplement, laboratory reagent
Manufacturer Information: [Manufacturer details]
Emergency Phone Number: [Emergency contact number, available 24 hrs]

Hazard Identification

GHS Classification: Not hazardous under GHS criteria
Signal Word: None
Hazard Pictograms: None
Hazard Statements: Low toxicity, may cause mild irritation to skin and eyes
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Do not inhale dust.

Composition / Information on Ingredients

Cyanocobalamin: ≥ 98%
Molecular Formula: C63H88CoN14O14P
Molecular Weight: 1355.38 g/mol
Impurities/Ingredients: Trace components determined by supplier manufacturing processes, usually insignificant for hazard profile

First Aid Measures

Inhalation: Move exposed person to fresh air. Seek medical attention for symptoms.
Skin Contact: Wash skin with soap and plenty of water. Get medical attention if irritation develops.
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses. Continue rinsing.
Ingestion: Rinse mouth with water. Seek medical attention if large quantities are swallowed or if symptoms persist.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards: Emits toxic fumes like nitrogen oxides, carbon oxides, cobalt oxides under fire conditions
Protective Equipment: Firefighters use full protective gear, self-contained breathing apparatus
Firefighting Instructions: Prevent discharge of extinguishing media to drains or watercourses

Accidental Release Measures

Personal Precautions: Avoid dust formation. Ensure proper ventilation. Wear protective equipment including gloves and goggles.
Environmental Precautions: Prevent entry into waterways, drainage systems, and soil.
Methods for Cleanup: Pick up powder using mechanical means, minimize dust. Sweep up and place in a suitable closed container for disposal. Use water spray to reduce dust if needed.

Handling and Storage

Handling: Avoid creating dust. Minimize exposure by wearing appropriate personal protective equipment. Wash hands after handling. Do not eat or drink in work area.
Storage: Keep container tightly sealed in a dry, cool, well-ventilated place away from direct sunlight and incompatible substances like strong oxidizers

Exposure Controls and Personal Protection

Occupational Exposure Limits: No data for Cyanocobalamin-specific exposure limits
Engineering Controls: Work in well-ventilated area or use local exhaust
Personal Protective Equipment: Safety goggles, gloves made of nitrile or latex, lab coat. Use dust mask or respirator during high dust generation.
Hygiene Measures: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse.

Physical and Chemical Properties

Appearance: Red to dark red crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH: Not determined (aqueous solutions slightly acidic)
Melting Point: > 300°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable
Flammability: Not flammable under normal conditions
Solubility: Soluble in water
Partition Coefficient: Not available
Vapor Pressure: Negligible
Relative Density: 1.42 g/cm³ (at 20°C)
Auto-ignition Temperature: Not applicable
Decomposition Temperature: > 300°C
Viscosity: Not applicable for a solid

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures, though sensitive to light
Conditions to Avoid: Excess heat, light, moisture
Incompatible Materials: Strong oxidizers, acids, and bases
Hazardous Decomposition Products: May release nitrogen oxides, carbon monoxide, carbon dioxide, cobalt oxides, and hydrogen cyanide in case of thermal decomposition
Reactivity: Reacts with strong chemicals as above, not reactive under recommended handling

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat) > 2,000 mg/kg
Skin and Eye Irritation: Possible mild irritation
Chronic Effects: Prolonged or repeated exposure may cause mild skin or respiratory irritation
Mutagenicity/Carcinogenicity: No data indicates mutagenic or carcinogenic effects.
Other Effects: Cyanocobalamin is an essential nutrient. Symptoms from low-level exposure highly unlikely, but inhalation exposure at high concentrations should be avoided.

Ecological Information

Ecotoxicity: Low expected environmental impact in typical lab or supplement use. No known bioaccumulation or significant aquatic toxicity.
Persistence and Degradability: Biodegradable, decomposes naturally in environment
Mobility in Soil: Soluble in water, expected to disperse and degrade
Other Adverse Effects: Not expected to pose hazard to environment in low concentrations. Avoid large releases to waterways to prevent unknown ecological consequences.

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations. Do not release to environment. Prevent large quantities from entering drains or watercourses.
Contaminated Packaging: Treat as chemical waste. Rinse thoroughly and recycle or dispose in accordance with official regulations.
Special Precautions: Handle unused product and waste with care, using proper personal protective equipment.

Transport Information

UN Number: Not regulated as dangerous for transport
UN Proper Shipping Name: Not applicable
Transport hazard class: Not applicable
Packing group: Not applicable
Marine Pollutant: Not classified as marine pollutant
Special Precautions for User: Protect against moisture, avoid rough handling, transport in original container whenever possible

Regulatory Information

OSHA: Not specifically regulated
TSCA: Listed
WHMIS Classification (Canada): Not a controlled product
REACH Registration (EU): Exempt as a vitamin
Other Regulatory Lists: Not subject to major restrictions or bans; compliance with general chemical safety standards required