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Product Name: Chenodeoxycholic Acid
Chemical Name: 3α,7α-Dihydroxy-5β-cholan-24-oic acid
CAS Number: 474-25-9
Recommended Use: Research, synthesis, pharmaceutical development
Supplier: Consult local or trusted global chemical supplier
Emergency Contact: Local emergency medical services or regional poison control
Synonyms: Chenic acid, Chenocholic acid
Molecular Formula: C24H40O4
Molecular Weight: 392.57 g/mol
Form: White to off-white crystalline powder
Unii Code: UJ3CFN2Q5A
GHS Classification: Not classified as hazardous under GHS guidelines; treat with caution
Hazard Statement: May cause eye or skin irritation
Signal Word: Warning
Pictogram: None required under typical regulatory status
Routes of Exposure: Inhalation, skin, ingestion, eye contact
Potential Health Effects: Irritation on contact, possible gastrointestinal discomfort if swallowed
Precautionary Statements: Avoid breathing dust; avoid prolonged contact with skin and eyes; handle under fume hood if possible
Other Hazards: Dust may form explosive mixture with air in rare settings
Chemical Identity: Chenodeoxycholic Acid
PURITY: ≥99% by HPLC
Impurities: Trace bile acids, water, inorganic salts (minimal if properly purified)
Additives: None
Ingredient Concentration: 100% active compound
CAS Number: 474-25-9
EC Number: 207-481-8
Inhalation: Move exposed person to fresh air; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash area with soap and plenty of water; seek advice if irritation lingers
Eye Contact: Flush eyes with water for at least 15 minutes; get medical attention if pain or redness continues
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical personnel; seek medical advice
Most Important Symptoms: Redness, itching, discomfort in eyes or on skin; mild stomach upset if swallowed
Immediate Medical Attention: Only required with persistent, severe symptoms or large exposure
Self-protection for First Aiders: Use gloves, avoid contact with skin and eyes
Suitable Extinguishing Media: Dry chemical, foam, or carbon dioxide; avoid high-pressure water streams
Special Hazards: Combustion yields carbon monoxide, carbon dioxide, possibly toxic fumes
Advice for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Combustion Products: Carbon oxides, other organic fumes
Protective Equipment: Chemical splash suit, gloves, face shield
Specific Methods: Move containers from fire zone if possible; cool with water fog if safe
Flammability: Solid, not highly flammable, but dust may be combustible
Personal Precautions: Wear gloves, safety goggles, dust mask or respirator
Environmental Precautions: Prevent spillage from entering drains or waterways
Clean-up Methods: Scoop or sweep up, avoid creating airborne dust
Containment: Surround with inert material such as vermiculite; transfer to sealed waste container
Decontamination: Wipe area with damp rags and dispose of material according to regulations
Spill Response Team: Trained lab or chemical personnel with PPE
Ventilation: Increase ventilation, evacuate area in case of large spill
Safe Handling: Wear lab coat, gloves, goggles; avoid ingestion, inhalation
Technical Measures: Use local exhaust, minimize dust production
Fire Prevention: Keep away from open flames and sources of ignition
Hygiene Measures: Wash hands and exposed skin after handling; do not eat, drink, or smoke in area
Storage Conditions: Store in tightly closed container in a cool, dry place
Compatibility: Segregate from strong oxidizing agents and acids
Temperature Limits: Room temperature (15-25°C) or as specified on product label
Special Packaging: Use chemical-resistant containers
Exposure Limits: No specific occupational exposure limits established
Engineering Controls: Work under fume hood, ensure good ventilation
Personal Protective Equipment (PPE): Nitrile gloves, safety goggles, lab coat
Respiratory Protection: Dust respirator for bulk handling or poor ventilation
Eye Protection: Chemical splash goggles
Hand Protection: Chemical-resistant gloves
Skin Protection: Long sleeves, chemical-resistant garments
Environmental Controls: Keep out of sewage and surface water
Appearance: White to off-white crystalline powder
Odor: Nearly odorless
Odor Threshold: Not determined
pH: 3.0–4.0 (1% aqueous)
Melting Point: 165–167°C
Boiling Point: Decomposes
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not classified as flammable
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: 1.31–1.32 g/cm³
Solubility: Slightly soluble in water, soluble in ethanol and methanol
Partition Coefficient: Log P ~3.0
Auto-ignition Temperature: Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable
Molecular Weight: 392.57 g/mol
Chemical Stability: Stable at room temperature under recommended conditions
Reactivity: No hazardous reactivity under normal storage and use
Conditions to Avoid: Moisture, strong oxidizers, strong acids or bases, excessive heat
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating organic fumes
Polymerization: Not anticipated
Acute Toxicity: Oral LD50 (rat) not precisely reported; considered low toxicity in animal data
Skin Irritation: Mild irritation possible
Eye Irritation: May irritate
Respiratory Irritation: Dust may irritate airways
Sensitization: Rare reports of allergic responses
Chronic Exposure: No data suggesting long-term health risks at low exposure
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: No known mutagenic effects
Reproductive Effects: No reproductive toxicity data in humans
Target Organ Effects: None expected with occupational exposure
Ecotoxicity: Not expected to pose significant hazard in dilute concentrations based on bile acid nature
Aquatic Toxicity: Low; compounds break down by natural bacterial action
Persistence and Degradability: Readily biodegradable
Bioaccumulation Potential: Low; not known to accumulate in aquatic organisms
Mobility in Soil: Moderate, depending on environment
Other Adverse Effects: None expected in typical lab waste quantities
Waste Treatment Methods: Handle as chemical waste; follow national and local regulations
Disposal of Product: Incineration in licensed facility or disposal through regulated chemical waste handler
Disposal of Contaminated Packaging: Triple rinse and dispose as hazardous waste
Environmental Precautions: Avoid release to environment, sewage, or open water
Recycling: Not practical at laboratory quantities
Special Instructions: Consult safety office or chemical management program for bulk quantities
UN Number: Not assigned
UN Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not classed as hazardous
Packing Group: Not classified
Environmental Hazards: None known
Transportation Requirements: Pack securely, avoid moisture and rough handling, protect from breakage
DOT (US): Not regulated
IMDG: Not regulated
IATA: Not regulated
Special Precautions: Standard care for powders and chemicals
TSCA (US): Listed or exempt
REACH (EU): Not specifically listed, generally exempt as natural product for research
IARC, NTP, OSHA: Not classified as carcinogen
SARA Title III: Not subject to special reporting
WHMIS (Canada): Not controlled
DSL/NDSL (Canada): Present or exempt
Chemical Inventories: Check region-specific regulations for chemical inventory listings
Label Requirements: GHS label with warning, avoid contact, and emergency instructions
Other Regulations: No REACH SVHC, not a controlled substance
