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Looking back, the late 1960s brought an urgent scramble in pharmaceutical circles. Hospitals wrestled with bacteria that grew smarter and more aggressive every year, so the hunt for new antibiotics reached a fever pitch. Cephalosporins, derived from Acremonium mold, had already made their mark, but researchers aimed for broader protection. Cefoxitin came out of these efforts. Developed by chemists working to modify natural cephalosporins, it entered clinical trials in the early 1970s, standing out as one of the first cephamycins. Its creators saw the potential for a robust molecule, tougher against gram-negative and anaerobic bacteria. By expanding the beta-lactam ring structure, after countless lab tweaks, scientists built in resistance to bacterial beta-lactamases, the enzymes that destroy penicillins and earlier cephalosporins. Cefoxitin’s U.S. FDA approval in 1975 changed hospital guidelines and offered another tool against surgical site infections as well as complications from stubborn bacteria. Since then, countless hospitals worldwide have counted on cefoxitin sodium as part of their routine protocol for both known and suspected mixed infections.
Cefoxitin sodium has become a staple in hospital medicine cabinets, usually found in sterile, white crystalline powder form packaged in vials for reconstitution. Its main job centers on intravenous and intramuscular delivery, taking advantage of its rapid onset of action. In my own experience working alongside hospital pharmacists, no one wants to lose time admiring a drug’s packaging — reliability and sterility matter more. Cefoxitin offers both. Pharmacists appreciate its compatibility with standard saline and glucose solutions, which makes mixing and preparation less stressful during emergencies. Compared to many antibiotics, cefoxitin often gets selected for its broad-spectrum powers without a sky-high risk of allergic reactions seen with penicillins.
Cefoxitin sodium’s physical appearance does not give away its importance. In its pure state, it forms a slightly off-white, odorless powder, dissolving quickly in water. The molecule itself, C16H16N3NaO7S2, brims with activity: a beta-lactam ring, a dihydrothiazine ring, and a methoxy group at position 7. That methoxy substituent pushes cefoxitin ahead in the fight against beta-lactamase-producing bacteria — a real game changer in treating Bacteroides fragilis or Escherichia coli. This structural backbone brings stability both in solution and in storage. Losing this stability can actually mean breakthrough infections, an all-too-common fear for infectious disease specialists.
Manufacturers like to pin down specifics for every batch and label. Cefoxitin sodium vials carry clear dosing guidelines, usually ranging from 1g to 2g per vial, tailored for direct mixing. Labels emphasize the sodium content per dose, which plays a crucial role in patients with strict salt restrictions. That one detail often sparks late-night discussions between renal and infectious disease teams. For the FDA, labeling remains clear: “for intravenous or intramuscular use”, with required notes on storage temperatures (typically 2–8°C), expiration date, and diluent compatibility. Warnings cover hypersensitivity, risks for C. difficile infection, and instructions for reconstituting solutions under sterile, controlled conditions. Each label follows standards set both in the United States Pharmacopeia (USP) and the European Pharmacopeia, so product quality targets are nearly universal.
Synthesizing cefoxitin sodium usually begins with cephamycin C fermentation from the Streptomyces lactamdurans or related strains. After extraction, the molecular structure gets tweaked, often using advanced chemical modification like oximation and methylation to set the methoxy group precisely in place. Process engineers must run multi-step purification and crystallization, each with careful control over temperature, solvent ratios, and reaction times. It takes years of experience — not to mention some real headaches — to scale up these procedures without losing yield or purity. By the time the powder hits the pharmacist’s shelf, it has passed through multiple solvent exchanges, washing, drying, milling, and stability checks. Every contamination risk gets scrutinized along the way, since injectable antibiotics demand higher purity than nearly any other drug class.
Cefoxitin sodium stands as a testament to clever chemistry. The starting material, cephamycin C, undergoes selective acylation at its amine group to introduce the carboxyl-linked side chain, making it more active and resistant to bacterial enzymes. Methylation at the 7α-position boosts stability. This chemical resilience means that cefoxitin not only survives in the bloodstream longer but also provides reliable protection against extended-spectrum beta-lactamases (ESBLs). Beyond initial synthesis, researchers keep looking for new derivatives — oxime modifications, new acyl side chains, and even non-beta-lactam analogues. Each tweak targets different resistance mechanisms, giving microbiologists better odds in the ongoing arms race with mutating bacteria.
Cefoxitin sodium goes by several names in the medical literature and on shelves. Some hospitals use brand names like Mefoxin or Cefoxitin for Injection. International listings sometimes feature Latin descriptors, such as “Cefoxitinum Natricum”. In China, hospitals request “头孢西丁钠”, reflecting a growing global presence. The World Health Organization and U.S. Pharmacopeia both list cefoxitin sodium as the official INN (International Nonproprietary Name). Pharmacies and wholesalers carry a host of generic cefoxitin sodium, all requiring government registration and batch-by-batch verification. For doctors and nurses working under pressure, clarity in naming helps avoid dangerous medication errors, especially in complex or multilingual hospital environments.
Sterile compounding procedures never leave room for shortcuts with cefoxitin sodium. Most hospital guidelines require trained staff to prepare syringes and IV bags inside certified laminar flow hoods to block contamination. Facilities set strict temperature and humidity ranges for storage. Even packaging gets checked for sterility. Nurses and pharmacy staff monitor lot numbers and expiration dates because a single error can mean severe or even fatal consequences. Adverse reactions, though less common than some older antibiotics, still warrant monitoring. Cefoxitin can provoke rashes, rare anaphylactic responses, or, in at-risk patients, drug-induced hepatitis. Infection control specialists stress the need for periodic education and observation of antibiotic stewardship, especially as pressure mounts to prevent antibiotic resistance. Hospitals also follow NIOSH and OSHA standards for handling cytotoxic or potentially hazardous medications, meaning gloves, goggles, and even designated disposal routes for unused drug.
Doctors trust cefoxitin sodium both for treating known infections and for surgical prophylaxis, especially in colorectal, gynecologic, and abdominal procedures. Surgeons have cited its reliability against bowel flora and anaerobes as a reason it remains a goto, even decades after its introduction. Obstetricians often reach for it during cesarean sections or to treat pelvic inflammatory disease, since it covers tough bugs like Bacteroides and Neisseria gonorrhoeae. Emergency departments stock it for mixed infections from traumatic injuries, where speed and spectrum count more than narrow targeting. In smaller clinics, it acts as the safety net for complicated urinary tract infections, or suspected sepsis when waiting on culture results isn’t an option. In both my own experience and in published medical studies, cefoxitin sodium routinely gets credit for reducing post-operative complications and driving down lengths of hospital stay—evidence that clinical guidelines aren’t just bureaucratic routine but real, lifesaving practice.
Research into cefoxitin sodium reflects the wider medical community’s shift to smarter antimicrobial use. Recent studies focus less on developing brand-new antibiotics and more on optimizing what’s already available. Pharmacologists have worked on extended infusion protocols and combination therapies using cefoxitin alongside other broad-spectrum agents. Laboratory scientists continue to monitor bacterial sensitivity, with real-time surveillance revealing shifting patterns of resistance—especially in the context of hospital-acquired infections. Data from the CDC and WHO keep underlining that while cefoxitin’s coverage has held up well, overuse or poor antibiotic stewardship can lead to spikes in resistant Enterobacteriaceae or C. difficile outbreaks. Academic centers run multidisciplinary trials, weighing cefoxitin’s performance against other options both in terms of patient outcomes and hospital resource allocation. These ongoing projects aim to squeeze more value from existing antibiotics as companies face regulatory and financial hurdles to inventing entirely new ones.
Toxicity remains a crucial concern for any injectable antibiotic, and cefoxitin sodium gets close scrutiny. Animal studies established a wide margin of safety, but human experience shapes safety protocols. Rare cases of acute interstitial nephritis or reversible hepatitis have cropped up, especially when high doses combine with other nephrotoxic medications. Hematologists keep watch for blood count changes, since cefoxitin can rarely trigger anemia or neutropenia. For patients with impaired renal function, dosing adjustments get built into most hospital protocols. Cefoxitin residues in post-surgical patients fall off quickly after therapy ends, which helps keep side effects manageable. Regulatory groups require regular pharmacovigilance, collecting and analyzing reports from clinicians to spot early warning signs of unexpected reactions. My own view as a collaborator on hospital pharmacy projects is that constant education, vigilant double-checking, and good communication between teams do more to prevent adverse effects than reliance on any label or guideline.
Cefoxitin sodium faces both challenges and new opportunities. In wealthy countries, pressure grows to reserve “last-line” agents, so cefoxitin’s strong safety record and broad coverage keep it in the game. In developing regions, where resistance rates fluctuate and resources run short, stable, effective antibiotics like cefoxitin form the backbone of hospital formularies. Ongoing R&D in antibiotic stewardship and customized dosing could further extend its useful lifespan. New trends might shift some uses toward targeted, shorter courses or as part of multi-drug regimens fighting multi-resistant strains. Biotechnology firms also keep searching for improved cephamycin-like molecules, aiming for even higher resistance barriers and lower side effect profiles. Growing databases on bacterial genomics and resistance patterns drive smarter use, helping ensure that cefoxitin sodium, rather than being a relic, remains a valuable weapon in the war against infectious disease. One lesson stands out: wise stewardship and sustained investment make all the difference in keeping these tools working.
Dealing with infections in a hospital, I’ve watched people come in with fevers, pain, and an unknown culprit stalking their body. Cefoxitin Sodium gets pulled from the pharmacy shelf when doctors don’t have time to waste guessing. Without fanfare, this medication works against a nasty swath of bacteria — including many that laugh in the face of older antibiotics.
Cefoxitin Sodium belongs to the cephalosporin group. Doctors pick it when skin, abdominal, pelvic, and even bone infections have likely grown resistant to other antibiotics. In intensive care, surgeons and infectious disease specialists value it for a reason: some bacteria have built strong resistance barriers, especially in places like hospitals where germs trade dirty tricks. Cefoxitin covers both Gram-positive and certain tricky Gram-negative bacteria, which means it tackles everything from E. coli to the unwelcome Staphylococcus.
Surgeons often stay up at night thinking about post-surgical infections—nobody wants an operation saved by skill and torpedoed by germs. Cefoxitin Sodium steps into the operating room before the first incision, running through the bloodstream to lower the chances that bacteria will sneak in and spoil a recovery. Obstetricians and gynecologists use it for surgeries involving the uterus and other pelvic organs. They know bacteria around these areas can turn a routine operation into a dangerous situation. For patients switching from penicillins due to allergy or resistance, cefoxitin gives them a fighting chance.
Gastrointestinal surgeries call for something tough. Anaerobic bacteria—bugs that hate oxygen and thrive deep in wounds or bowel contents—have proven stubborn. I’ve seen Cefoxitin become the go-to option for colorectal procedures because it keeps these hard-to-kill bugs in check, preventing infections that could turn deadly.
Antibiotic resistance isn’t just a medical buzzword. Bacteria have grown smarter, swapping genes that dodge penicillins or even older cephalosporins. Cefoxitin has held the line longer than most. In some parts of the world, it still knocks out methicillin-resistant Staph (MRSA), though this is changing. We have to be careful: overusing any antibiotic, even Cefoxitin, risks encouraging resistance. Stewardship programs must keep track of cefoxitin orders and educate healthcare workers on wise use. Every dose handed out ought to count.
Some patients experience side effects: allergic reactions, kidney concerns, or irritation at injection sites. These problems can’t be brushed aside. As with any antibiotic, doctors weigh the risks, monitor closely, and only prescribe Cefoxitin for infections proven or strongly suspected to involve susceptible bacteria. Speed matters, but so does careful testing—laboratories play a huge role in matching the right drug to the right bug.
No one wants to face a post-surgical infection or a hospital-acquired pneumonia alone. Cefoxitin Sodium, in experienced hands, turns the tide for patients fighting off resistant bacteria. Wise choices, careful monitoring, and ongoing research will help keep this medication effective, giving future patients a real shot at recovery.
Antibiotics support daily hospital work in ways that often go unseen by anyone outside the medical field. Cefoxitin Sodium stands as one of those go-to antibiotics, especially for folks dealing with tough infections. I've watched infectious disease teams in action, weighing medication choices not just on the name of the bug, but also on how the drug fits the patient's day-to-day care. That perspective shapes how Cefoxitin Sodium shows up in treatment plans.
You won't find patients taking Cefoxitin Sodium by mouth. The gut just won't soak up this medication. Nurses and doctors use injections, either directly into a vein or deep into a muscle. For serious infections, intravenous (IV) delivery really takes the lead. A nurse attaches a syringe to an IV line, pushes the mixed antibiotic straight into the bloodstream, or sets up a slow drip bag. IV administration means the entire dose goes right to work without delay, which can be the difference between steady recovery and brewing complications.
In some cases, when a patient's veins need a break or if the infection looks mild, intramuscular shots fill the gap. The shot goes straight into muscle tissue, releasing medicine a bit slower—but for many people outside the intensive care unit, this approach is more than enough.
The exact way Cefoxitin Sodium gets delivered isn’t up for debate; getting it wrong can seriously harm a person. Giving it by mouth does nothing. Giving it too quickly in a vein could trigger sudden reactions. Diluting it wrong or ignoring proper mixing steps could clog up the IV or cause pain at the injection site. Healthcare workers follow detailed instructions for good reason—and for anyone who questions that, ask a nurse about what happens if a line infiltrates and leaks medicine under the skin.
I've seen cases where faster isn’t better. A slow infusion lets the body handle the dose without overwhelming the kidneys or causing discomfort. Hospitals log every detail of timing, dose, and delivery site because there’s just too much to lose by getting sloppy.
No antibiotic works for everyone the same way. Some patients break out in rashes or itch from head to toe—classic drug reactions. Others report pain at the site of the shot, or notice swelling in the arm with the IV. Nurses stay watchful for all these issues, ready to switch up medications or adjust the pace. Allergic reactions get sorted out fast: sometimes with antihistamines, sometimes with an entirely new plan. Respecting individual body differences goes beyond simple protocol. Hospital teams pay attention to kidney function and past allergies to avoid doing more harm than good.
Even top antibiotics have limits. Overuse or incorrect dosing gives bacteria more chances to fight back—a lesson antibiotic stewardship teams teach over and over. Only patients who truly need strong coverage should get these drugs. It helps everyone if patients or caregivers keep track of how they feel and report new symptoms early.
Hospitals can improve safety by investing in staff education, supporting clear communication among doctors, nurses, and pharmacists, and sticking to solid documentation. Anyone receiving Cefoxitin Sodium deserves full, careful treatment—and that only happens by respecting each step from the pharmacy to the bedside.
Cefoxitin sodium treats serious bacterial infections, often those tough hospital bugs that don’t respond to milder remedies. Hospitals and clinics use it for pneumonia, skin infections, pelvic issues, and after surgeries to stop infections before they start. Cefoxitin belongs to the cephalosporin family, a group that’s been saving lives since the 1960s. But even tried-and-true antibiotics can bring some unwelcome side effects. People deserve to know what they’re facing before a doctor hangs the IV bag.
Most people tolerate cefoxitin without too much trouble. Upset stomach comes up a lot; nausea, vomiting, or loose stools appear in quite a few cases. That miserable rumble in the gut is familiar to anyone who’s had a strong antibiotic. Doctors tell patients to eat bland foods and drink more water. A smart move, since dehydration can hit hard with diarrhea.
Cefoxitin, like its antibiotic cousins, can mess with gut bacteria. Patients sometimes develop a nasty overgrowth called Clostridioides difficile, which causes severe diarrhea and abdominal pain. C. diff infections have been rising in recent years, partly because of tougher antibiotics. Anyone who notices bloody stools, a fever, or cramps needs prompt attention. Hospitals know this risk and monitor closely, but families should never ignore these symptoms.
Rashes can show up after starting cefoxitin. Small red spots or itchiness aren’t rare, and sometimes a full-blown allergic reaction appears. I’ve seen patients who did fine on penicillin suddenly break out in hives or start wheezing after a cephalosporin dose. These signs mean the body’s not happy with the drug. Breathing trouble, swelling in the face or throat, and dizziness point to a medical emergency. Nurses in infusion areas expect this but need everyone around to speak up quickly.
Cefoxitin can put a strain on kidneys, especially for older adults or people with pre-existing kidney problems. Lab teams keep an eye out for changes in creatinine levels in the blood, which indicate kidney stress. Symptoms such as swelling in the legs, less urination, or unusual tiredness can be warning signs. Those aren’t symptoms folks easily connect to an antibiotic, but doctors recognize the risk, particularly for patients getting long courses.
Some people develop changes in their blood counts. Cefoxitin affects the way the bone marrow churns out cells, so anemia, low platelets, or low white blood cells can develop. Usually, these bounce back after stopping the drug, but regular blood tests matter. Hospital staff watch for unexplained fatigue, more infections, or easy bruising in patients. A simple blood draw can catch problems before they spiral.
Cefoxitin saves lives, no question. With the growing threat of antibiotic resistance, using strong antibiotics only when necessary protects future patients. People benefit when prescribers review allergies, kidney function, and recent antibiotic use before beginning treatment. Every hospital room should come with a dose of vigilance—a nurse checking in about diarrhea, a pharmacist reminding staff about blood draws, a family member ready to call for help if something goes wrong. These small steps go a long way in keeping people safer during tough treatments.
Education makes a difference. Anyone starting cefoxitin has a right to know about side effects that matter. It takes more than just a list in the paperwork. Honest conversations between care teams and patients can catch problems early and give people the confidence to speak up about symptoms. That’s the foundation of safer antibiotic use and stronger trust in care.
Doctors pull out Cefoxitin Sodium for serious bacterial infections. It handles a lot of tough bugs, including some strains other antibiotics cannot touch. That power makes it valuable, but not everyone with an infection benefits from getting it. For some, one dose can lead to more harm than good, so understanding the risks goes beyond scanning a list of side effects.
Allergies to antibiotics rarely stay mild. I’ve seen hives, red blotches, swelling, or in the worst cases, life-threatening reactions. Cefoxitin belongs with the cephalosporin family. If you've ever had trouble after a dose of penicillin or similar drugs, the warning lights really go off. Studies show that about one in ten people allergic to penicillin might also react to cephalosporins like cefoxitin. That statistic sits with me every time a patient mentions allergies in their chart. Knowing your drug history keeps you safer than anything else.
Healthy kidneys help the body clear out leftover drugs. In hospital wards, folks with kidney problems always need a closer look before getting injectable antibiotics. Cefoxitin leaves the body through urine; impaired kidneys let it build up, making complications more likely. Doctors often lower the dose for those on dialysis or with weak renal function, checking lab values before and during treatment. The same caution goes for serious liver disease. Broken livers and kidneys change the game—nobody wins by ignoring those numbers.
Tough antibiotics can throw off the natural balance in the gut, opening the door to dangerous bugs like Clostridioides difficile. Cefoxitin isn’t immune; it can wipe out friendly bacteria, letting bad actors multiply. That turns into cramping, diarrhea, or even deadly colitis if things spiral. The CDC has hammered home this point for years: always weigh the infection risk against long-term gut health. Good doctors ask about past C. diff episodes and make sure patients report digestive issues fast.
Nobody likes a surprise drug reaction. Cefoxitin mixed with other antibiotics or blood thinners like warfarin has triggered problems before. It can bump up or drop the way those drugs work, so sharing a complete medication list with the care team can sidestep hospital headaches. Older adults especially should have a precise record—one missed detail, and bleeding risks can skyrocket.
Always start with clear conversations: lay out your health history, including past reactions and chronic illnesses. Bring a current medication and supplement list. Common-sense steps, like asking about possible alternatives and understanding emergency symptoms, help turn a prescription into safe healing. The importance of rapid reporting can’t be overstated—strange rashes, shortness of breath, sudden stomach pain—all deserve a call, not a wait-and-see approach. For those with question marks in their history, allergy testing isn’t overkill. One test could dodge days in the ER.
Cefoxitin Sodium plays a key role in saving lives, but every powerful tool comes with responsibility. It’s on all of us—doctors, nurses, patients, and caregivers—to respect these warnings and aim for the safest possible outcome. Everyone has a part to play in making antibiotics work for the next illness, not just today’s.
Every hospital and clinic depends on antibiotics like Cefoxitin Sodium to fight off stubborn bacterial infections. I’ve seen how crucial these drugs are when sepsis looms or post-surgical wounds threaten to spiral out of control. Safe storage often gets overlooked, but it can make the difference between a lifesaving dose and an inactive vial. Cefoxitin Sodium, usually found as a powder for injection, doesn’t like heat or moisture. Pharmacy shelves crowd with drugs, yet this one demands special respect. Keeping it at room temperature, away from direct sunlight, shields the powder from degradation. Tossing it on a windowsill or next to a radiator takes that protection away. Moisture seeps in, ruining the drug long before it ever gets drawn up for an IV.
Many healthcare workers hustle through busy shifts, sometimes forgetting that one misplaced vial could become useless or, worse, dangerous. A sudden temperature shift—maybe from an AC unit breaking or a storeroom being left open—doesn’t just shrink the shelf life. It invites bacterial growth if vials get damp, or can even spark chemical changes that make the antibiotic less reliable. I’ve watched nurses and pharmacists grumble about wasting expensive medicine when careless storage forces them to toss supplies. This isn’t just a hit to a hospital’s budget. It delays treatment and throws timetables into chaos when a drug shortage means running to another department or even waiting for a new shipment.
Pharmacy teams get told to store Cefoxitin Sodium below 25°C (77°F), tightly sealed in its original container. Dry cabinets, not fridges unless the label says so, work best. In real life, that might mean stashing it away from cleaning supplies, food, or anything that could introduce odd smells or contaminants. Even in busy clinics, a dedicated shelf—well-marked, high up, out of sunlight—goes a long way. After mixing with sterile water for injection, the solution only hangs onto its potency for about 24 hours at room temperature or a week if refrigerated. That time goes fast, especially with rotating staff. Labeling mixed vials with dates and times keeps mistakes at bay.
It’s easy to talk about the right way to store antibiotics, but practical steps stick harder when they save someone’s life. Setting up quick reminders in break rooms, providing insulated storage containers for clinics without climate control, and sticking visual guides above shelves can cut down on mishaps. Automation helps when barcodes or electronic inventory tools flag meds that have been out of spec. Training often falls short, but bringing real-world stories—how a spoiled vial meant a longer ICU stay, for instance—grabs attention better than official memos. I’ve noticed that staff turnover wrecks consistency, so regular in-person check-ins, even five-minute reminders during shift changes, pay off in reduced waste and better patient outcomes. Keeping storage tight and supplies reliable doesn’t just protect inventory. It honors the trust patients put in their care teams at their sickest moments.
| Names | |
| Preferred IUPAC name | Sodium (6R,7S)-3-[(acetoxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| Other names |
Mefoxin Celaxitin Cefoxitina Cefoxitinum Mefoxitin |
| Pronunciation | /siːˈfɒk.sɪ.tɪn ˈsoʊ.di.əm/ |
| Identifiers | |
| CAS Number | 33564-30-6 |
| Beilstein Reference | 3957039 |
| ChEBI | CHEBI:3527 |
| ChEMBL | CHEMBL1782 |
| ChemSpider | 5751 |
| DrugBank | DB01331 |
| ECHA InfoCard | 100.071.243 |
| EC Number | 61177-45-5 |
| Gmelin Reference | 83432 |
| KEGG | D00259 |
| MeSH | D003022 |
| PubChem CID | 441372 |
| RTECS number | XT2350000 |
| UNII | 1LGS5QYFOQ |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DJ3312H3MO |
| Properties | |
| Chemical formula | C16H16N3NaO7S2 |
| Molar mass | 449.34 g/mol |
| Appearance | White to off-white crystalline powder |
| Odor | Odorless |
| Density | 1.95 g/cm3 |
| Solubility in water | Soluble in water |
| log P | -2.2 |
| Vapor pressure | Negligible |
| Acidity (pKa) | 2.7 |
| Basicity (pKb) | 7.2 |
| Magnetic susceptibility (χ) | -11.0 x 10⁻⁶ cm³/mol |
| Dipole moment | 1.82 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 322.8 J·mol⁻¹·K⁻¹ |
| Pharmacology | |
| ATC code | J01DC01 |
| Hazards | |
| Main hazards | Main hazards: Harmful if swallowed. May cause allergic skin reaction. Causes serious eye irritation. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | GHS05,GHS07 |
| Signal word | Warning |
| Hazard statements | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | P264, P270, P272, P273, P280, P302+P352, P305+P351+P338, P308+P311, P333+P313, P362+P364, P501 |
| NFPA 704 (fire diamond) | NFPA 704: 2-3-0 |
| Lethal dose or concentration | LD50 (intravenous, mouse): 4000 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse intravenous 6000 mg/kg |
| PEL (Permissible) | 140 mg/m³ |
| REL (Recommended) | 2 g every 6 hours |
| Related compounds | |
| Related compounds |
Cephamycin C Cephalothin Cephalosporin C Cefotetan Cefmetazole Cefamandole Cefuroxime |
