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Product Name: Bacitracin Zinc
Synonyms: Bactitracin, Bacitracin with Zinc Salt
Recommended Use: Topical antibiotic treatment
Manufacturer: Identified on packaging or supplier invoice
Emergency Contact: Refer to local supplier or Poison Control Center
CAS Number: 1405-89-6
Product Code: Refer to batch identification provided on container
Classification: Eye irritation, Respiratory tract irritation, Mild skin sensitization, Non-flammable
Signal Word: Warning
Hazard Pictograms: Exclamation mark for irritation
Hazard Statements: Causes mild skin and eye irritation, may provoke allergic response in sensitive individuals
Precautionary Statements: Avoid inhalation, wear protective gloves and eyewear during handling, wash hands after use, keep away from food and drink
Routes of Exposure: Eyes, skin, inhalation
Chemical Name: Bacitracin Zinc
Chemical Family: Polypeptide antibiotic
Component: Bacitracin (primary), Zinc (added salt)
CAS Numbers: Bacitracin: 1405-87-4, Zinc: 7440-66-6
Concentration: Often contains 500 units/g in topical products, zinc content varies by formulation
Other Ingredients: Excipients such as petrolatum, mineral oil may be present in formulated topical ointments
Inhalation: Move to fresh air, seek medical assistance if breathing becomes difficult or symptoms persist
Skin Contact: Wash area with soap and water, remove contaminated clothing, get medical help if irritation occurs
Eye Contact: Rinse eyes with water for at least 15 minutes, hold eyelids open, consult medical personnel if redness or pain persists
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical attention for any swallowed amount
Note for Physicians: Treatment is symptomatic, allergic reactions may require antihistamines or corticosteroids
Suitable Extinguishing Media: Water spray, CO₂, dry chemical, foam
Unsuitable Extinguishing Media: None identified
Fire Hazards: Bacitracin zinc itself is not flammable; burning packaging may release toxic fumes including nitrogen oxides, sulfur oxides, zinc oxides
Special Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Specific Fire-Fighting Methods: Prevent contaminated fire water from entering drains
Hazard Combustion Products: Acrid smoke, oxides of zinc and nitrogen
Personal Precautions: Avoid contact with eyes and skin, provide adequate ventilation, use protective equipment
Spill Procedures: Scoop solid material into suitable container, wipe area with damp cloth, wash residue with soap and water
Environmental Precautions: Do not release into drains or water sources, collect spilled residue promptly
Methods for Cleaning Up: Use appropriate PPE, dispose collected material in accordance with national regulations
Handling: Minimize dust formation, avoid direct contact with skin, eyes, and clothing, do not eat, drink or smoke during use, wash hands thoroughly after handling
Storage: Store at controlled room temperature (15–25°C), keep containers tightly closed, protect from moisture and direct sunlight, store away from incompatible chemicals (acids, strong oxidizers)
Specific Usage Considerations: Only use with appropriate personal protective measures in place, keep out of reach of children
Exposure Limits: No established occupational exposure limits for bacitracin zinc itself
Engineering Controls: Use local exhaust or general ventilation to limit airborne concentrations
Personal Protection: Wear gloves, safety goggles, and laboratory coat; use a mask in case of airborne dust formation
Hygiene Measures: Remove contaminated clothing after work, wash hands before eating, refrain from touching face during handling
Environmental Controls: Use spill control for powdered or bulk material, collect and dispose of waste as per local requirements
Appearance: White to off-white powder or ointment (topical formulation)
Odor: Odorless or slight medicinal smell
pH: Neutral to slightly acidic in aqueous solution
Melting Point/Range: Not applicable (decomposes before melting)
Solubility: Slightly soluble in water, freely soluble in saline
Specific Gravity: Not applicable for powder or ointment
Boiling Point: Not determined
Flash Point: Not determined (not considered a fire or explosion hazard)
Partition Coefficient: Not determined
Chemical Stability: Stable under recommended storage and handling conditions
Incompatible Materials: Strong oxidizing agents, acids, bases may degrade active compound
Reactivity: Little reactivity under normal use conditions
Hazardous Decomposition Products: May include zinc oxide, nitrogen oxides, and sulfur oxides upon combustion
Conditions to Avoid: Moisture, exposure to strong oxidizers or acids, high temperatures
Polymerization: No hazardous polymerization expected
Acute Toxicity: Oral LD50 (rat) >5,000 mg/kg; low systemic toxicity by topical exposure
Skin Effects: Mild irritant, possible allergen in sensitive individuals, risk of dermatitis following prolonged exposure
Eye Effects: Mild irritation with potential redness or pain
Respiratory Effects: Irritation possible if dust or aerosol is inhaled
Chronic Effects: Repeated or prolonged exposure may provoke allergic skin reactions
Carcinogenicity: No ingredients classified as carcinogen by IARC, NTP, OSHA
Other Data: Not mutagenic or teratogenic in most test systems, zinc absorption low via intact skin, higher risk through broken skin
Toxicity to Aquatic Organisms: Not acutely toxic in small releases, data suggest minimal environmental hazard at anticipated concentrations
Persistence: Degradable over time; information on environmental half-life limited
Bioaccumulation Potential: Bioaccumulation not expected in aquatic organisms due to molecular properties
Mobility in Soil: Tends to bind to soil particles, unlikely to infiltrate groundwater in significant concentrations
Other Environmental Impacts: May contribute to antibiotic resistance development in waters with repeated discharge
Waste Disposal Methods: Dispose of unused or expired material through licensed waste collection contractors
Container Disposal: Decontaminate and recycle or destroy by incineration according to local regulations
Safe Handling of Waste: Wear protective gloves and mask during cleanup, avoid creating dust
Regulatory Requirements: Follow local, regional, and national disposal regulations for pharmaceuticals and antibiotics
UN Number: Not assigned for this substance
UN Proper Shipping Name: Not classified as dangerous for transport
Transport Hazard Class: Not a hazardous or restricted material under transport regulations
Packing Group: Not applicable
Environmental Hazards: None required for regular shipment
Special Precautions for User: Avoid rough handling of bulk containers, store away from food products
Status under Chemical Regulations: Listed under applicable sections in TSCA (USA), REACH (EU), and respective national inventories
Labeling Requirements: Hazard pictograms and warning statements for occupational packaging
Risk Phrases: May cause skin and eye irritation, allergic reactions possible
SARA Title III Sections 302/304/311/312/313 (USA): Not listed as extremely hazardous or reportable
Other Regulatory Approvals: Approved for topical over-the-counter use in many markets; prescription control may apply in certain countries
Workplace Controls: Occupational exposure controls enforced through site procedures
