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Material Safety Data Sheet (MSDS) – Amitraz

Identification

Product Name: Amitraz
Chemical Name: N,N'-[(methylimino)dimethylidyne]di-2,4-xylidine
Synonyms: Mitac, Baam, Triazapentadiene
CAS Number: 33089-61-1
Intended Uses: Insecticide, acaricide for agriculture and animal health
Supplier/Manufacturer: Check with local distributor for manufacturer details in your country
Emergency Contact: Emergency hotlines for chemical exposure or spills often provided by national poison control centers

Hazard Identification

Classification: Harmful if swallowed, toxic in contact with skin, irritating to eyes and respiratory tract
Signal Word: Warning
Hazard Statements: May cause drowsiness, dizziness; toxic to aquatic life; harmful for mammalian nervous systems
Precautionary Statements: Wear protective gloves, avoid inhalation, prevent release to environment
Symbol(s): Exclamation mark, Environment
Routes of Exposure: Inhalation, skin contact, ingestion

Composition / Information on Ingredients

Chemical Formula: C19H23N3
Main Ingredient: Amitraz (technical) 98–100%
Impurities: Dimethylformamide (<0.5%), xylene residues, trace synthetic intermediates
Other Components: No other declared hazardous impurities at relevant concentrations

First Aid Measures

Eye Contact: Rinse with gentle stream of water for at least 15 minutes, remove contact lenses, seek medical advice without delay
Skin Contact: Wash off with lots of water and soap; remove contaminated clothing, seek medical attention if irritation persists
Inhalation: Remove from exposure, move to fresh air, keep comfortable, call for medical assistance if breathing problems occur
Ingestion: Do not induce vomiting, rinse mouth, provide water if person is conscious, get medical help quickly
Key Symptoms: Drowsiness, muscle tremors, reduced blood pressure, increased heart rate, coordination problems

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray or fog
Specific Hazards: Combustion produces toxic fumes including carbon oxides, nitrogen oxides; amitraz can release irritants under high heat
Protective Equipment: Use full protective gear and self-contained breathing apparatus for large fires
Advice for Firefighters: Avoid breathing vapors; dike fire control water for later disposal; cool tanks with water spray to prevent rupture
Explosion Hazard: No explosive properties under normal handling

Accidental Release Measures

Personal Protection: Use personal protective equipment such as gloves, goggles, disposable coveralls
Spill Cleanup Methods: Contain and absorb with earth, sand, or similar inert absorbent, collect and place into suitable containers
Environmental Precautions: Prevent entry into drains, surface and ground waters; report significant releases to authorities
Decontamination: Wash spill area thoroughly with detergent and water after material is collected
Disposal: Transfer waste to authorized chemical disposal facilities

Handling and Storage

Handling Precautions: Wear adequate personal protection, avoid contact with skin, eyes, and clothing, minimize dust and vapor generation
Safe Storage Conditions: Store in original tightly closed containers in a cool, dry, ventilated area; keep away from heat and direct sunlight
Incompatible Materials: Strong oxidizing agents, acids, alkalis
Hygiene Measures: No eating, drinking or smoking in work area; always wash hands after handling; keep away from food and animal feed
Special Provisions: Keep away from children and unauthorized personnel

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits established; use technical controls to minimize exposure
Engineering Controls: Local exhaust ventilation or general dilution ventilation in workspaces
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, face shield, long-sleeved clothing, boots
Respiratory Protection: Use NIOSH/MSHA-approved respirators in cases of high concentration
Environmental Exposure Controls: Use techniques to prevent environmental contamination; maintain spill control and containment

Physical and Chemical Properties

Appearance: Off-white to yellow powder
Odor: Slightly aromatic
pH: 6–8 (1% solution)
Melting Point: 86–87°C
Boiling Point: Not determined (decomposes before boiling)
Flash Point: >150°C
Solubility: Insoluble in water, soluble in organic solvents such as xylene and acetone
Vapor Pressure: Low (1.25 x 10-6 mm Hg at 25°C)
Relative Density: 1.1–1.2 g/cm³
Partition Coefficient (log Kow): 5.5

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Conditions to Avoid: Heating above decomposition temperature, exposure to sunlight or ultraviolet light
Materials to Avoid: Strong acids, oxidizers, strong bases
Decomposition Products: Produces carbon monoxide, carbon dioxide, nitrogen oxide gases, and aromatic amines when heated to decomposition
Reactivity Profile: Low reactivity; does not polymerize spontaneously

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 200–500 mg/kg; Dermal LD50 (rat): 1600 mg/kg
Chronic Effects: Prolonged or repeated exposure may affect liver and nervous system
Symptoms: Drowsiness, ataxia, decreased body temperature, reduced motor coordination, vomiting
Carcinogenicity: No evidence of carcinogenicity in animal studies
Mutagenicity: No mutagenic effects detected in standard test systems
Reproductive Toxicity: Not classified as a reproductive toxin based on current animal data
Sensitization: Possible skin sensitizer in susceptible individuals

Ecological Information

Ecotoxicity: Highly toxic to aquatic organisms (fish LC50 0.5–1.5 mg/L)
Persistence and Degradation: Moderately persistent, partial breakdown over several weeks in soil or water
Bioaccumulation Potential: High (log Kow >5), can accumulate in aquatic food chains
Mobility: Low mobility in soil; binds strongly to organic matter
Environmental Fate: Risk of runoff if applied near surface water; breakdown products can be toxic to non-target species

Disposal Considerations

Waste Treatment: Dispose of material through licensed hazardous waste contractor
Methods: Incineration at high temperature preferred, according to national and local laws
Container Disposal: Triple rinse containers, puncture, and dispose of in accordance with regional regulations
Avoid: Disposal into natural water bodies, sewer systems, or landfill without treatment

Transport Information

UN Number: 2588
Shipping Name: Pesticide, solid, toxic, organic, n.o.s. (contains amitraz)
Transport Class: 6.1 (Toxic substances)
Packing Group: III
Labels: Toxic substance, environmental hazard
Special Precautions: Prevent spillage during transit; notify emergency services in case of major spill; comply with road, rail, marine, and air transport regulations

Regulatory Information

Global Inventories: Listed on TSCA (US), EINECS/ELINCS (EU), AICS (Australia), DSL (Canada)
Hazard Symbols: Xn (Harmful), N (Dangerous for the environment)
EU Risk Phrases: R22 (Harmful if swallowed), R43 (May cause sensitization by skin contact), R50/53 (Very toxic to aquatic organisms, may cause long-term adverse effects)
SARA Title III: Not regulated as extremely hazardous substance in the US
OSHA: Not subject to specific regulation, standard chemical hygiene principles apply
Local Regulations: See country-specific pesticide control or environmental protection authority requirements for registration, use, and disposal