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Material Safety Data Sheet: Aloxicillin Sodium

Identification

Product Name: Aloxicillin Sodium
Chemical Formula: C16H18N3NaO5S
Synonyms: Sodium Aloxicillin, Aloxicillinum Natricum
Recommended Use: Pharmaceutical antibiotic, veterinary use, laboratory research
Supplier Identification: Manufacturer and distributor contact information listed on shipment documentation
Emergency Phone: Refer to local regulations or safety office
CAS Number: 35765-39-2

Hazard Identification

Hazard Class: Not classified as a hazardous substance under normal use but may cause sensitization, eye or respiratory irritation
GHS Classification: Possibly skin irritant, respiratory sensitizer
Signal Word: Warning
Hazard Statements: May be harmful if swallowed, may cause skin and eye irritation, may cause allergic respiratory reactions in sensitive individuals
Precautionary Statements: Avoid skin and eye contact, wear protective gear, handle in well-ventilated area

Composition / Information on Ingredients

Chemical Name: Aloxicillin Sodium
Concentration: 98-100% pure substance
CAS Number: 35765-39-2
Molecular Weight: 399.39 g/mol
Impurities: Trace organic or inorganic residues <1%

First Aid Measures

Inhalation: Move to fresh air, seek medical attention for persistent symptoms such as wheezing or coughing
Skin Contact: Remove contaminated clothes, wash skin with soap and plenty of water, seek medical advice for irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical advice
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention immediately
Most Important Symptoms: Potential allergic response, rash, shortness of breath, irritation to eyes or mucous membranes

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Unsuitable Extinguishing Media: High-pressure water jets
Special Hazards: Smoke, oxides of carbon, nitrogen, sulfur may be released
Protective Equipment: Firefighters must wear self-contained breathing apparatus and full protective gear, avoid inhalation of combustion products
Hazardous Combustion Products: Carbon monoxide, nitrogen oxides, sulfur oxides, sodium compounds

Accidental Release Measures

Personal Precautions: Avoid dust formation, ventilate area, use personal protective equipment
Environmental Precautions: Prevent further leakage, do not let product enter drains, soil, or surface water
Spill Cleanup Methods: Sweep up and place in suitable container for disposal, clean spill site with water and detergent, avoid raising dust

Handling and Storage

Handling Precautions: Wear protective gloves, safety glasses, lab coat, avoid breathing dust, wash hands thoroughly after handling
Storage Requirements: Keep container tightly closed in a dry, well-ventilated place, store between 2–8°C, protect from light
Incompatible Materials: Strong acids, strong bases, oxidizing agents

Exposure Controls and Personal Protection

Engineering Controls: Use laboratory fume hood or equivalent ventilation
Eye Protection: Chemical safety goggles
Skin Protection: Chemical-resistant gloves, protective clothing
Respiratory Protection: Dust mask or respirator if powder forms or dust is generated
Hygiene Measures: Avoid contact with skin, eyes, clothing, avoid breathing dust, always wash hands after handling

Physical and Chemical Properties

Appearance: White to off-white powder
Odor: Odorless
pH: Neutral to slightly alkaline in aqueous solution
Melting Point: Decomposes above 200°C
Boiling Point: Not applicable
Flash Point: Not flammable
Solubility: Soluble in water, sparingly soluble in alcohol
Stability: Stable under normal storage conditions
Partition Coefficient: Data not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: No dangerous reactions known under normal conditions
Conditions to Avoid: Excess moisture, extreme heat, direct sunlight
Materials to Avoid: Strong acids, strong bases, strong oxidizers
Decomposition Products: May release toxic fumes such as CO, SOx, NOx when heated to decomposition

Toxicological Information

Acute Toxicity: Oral LD50 in rats > 5,000 mg/kg, expected to have low acute toxicity
Skin Irritation: Prolonged exposure may cause irritation in sensitive individuals
Eye Irritation: May cause mild to moderate irritation
Respiratory Sensitization: May cause allergic reactions, bronchospasm in sensitized persons
Chronic Effects: Repeated exposure may sensitize or cause allergy
Carcinogenicity: No data to indicate carcinogenic potential
Mutagenicity: No significant mutagenic effects reported
Reproductive Toxicity: No relevant data available

Ecological Information

Ecotoxicity: Limited data, potential for impact on aquatic organisms if released in significant quantities
Degradability: Expected to degrade slowly in the environment
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Moderate mobility due to water solubility, risk of contamination from large spills
Other Adverse Effects: Do not discharge into surface water or sewage

Disposal Considerations

Waste Disposal: Dispose of as hazardous chemical waste, comply with local, regional, national regulations
Container Disposal: Triple rinse container, render unusable, dispose according to environmental standards
Waste Code: Appropriately assigned by local authority based on waste analysis
Precautions: Do not allow product to reach sewage, watercourse, or soil

Transport Information

UN Number: Not classified as dangerous for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Marine Pollutant: Not listed as marine pollutant
Special Precautions: Minimize vibration and exposure, keep packaging intact, avoid moisture

Regulatory Information

Labeling: GHS-compliant labeling recommended, precautionary information included
Occupational Exposure Limits: None established specifically for Aloxicillin Sodium
OSHA Status: Not listed as hazardous under OSHA HCS
REACH Registration: Not regulated under REACH
TSCA: Not listed
Other Regulations: Follow all applicable local workplace safety and environmental laws, consult country-specific requirements for pharmaceuticals or research chemicals