© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Name: 2,4-Dimethylpyridine
Chemical Formula: C7H9N
Synonyms: 2,4-Lutidine
Appearance: Colorless to pale yellow liquid
Odor: Strong, pungent, pyridine-like smell
Uses: Intermediate in organic synthesis, solvent in laboratory settings, raw material for chemical manufacturing
Acute Risks: Flammable liquid, toxic if swallowed or inhaled, serious eye and skin irritant, respiratory irritant
Chronic Risks: Long-term exposure can cause neurological effects, liver and kidney damage
GHS Classification: Flammable liquids Category 3, Acute toxicity Category 4 (oral and inhalation), Skin irritation Category 2, Eye irritation Category 2A
Signal Word: Warning
Symptoms: Irritation of eyes, skin, respiratory tract, potential headache, dizziness, nausea
Chemical Name: 2,4-Dimethylpyridine
Concentration: Generally supplied at 98% or higher
Impurities: Trace pyridine derivatives, assay typically establishes purity in high-grade samples
CAS Number: 108-47-4
Inhalation: Move the person to fresh air, keep comfortable for breathing, seek medical advice if symptoms persist
Skin Contact: Immediately wash with plenty of water, remove contaminated clothing, if skin irritation occurs, get medical attention
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical attention for persistent irritation
Ingestion: Rinse mouth, do not induce vomiting, call a poison center or physician if feeling unwell
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Media: Direct water jet may spread the fire
Hazards in Fire: Produces toxic fumes, including nitrogen oxides and carbon monoxide
Protective Equipment: Full protective gear and self-contained breathing apparatus
Fire-Fighting Tactics: Contain runoff to prevent entry into drains, stay upwind to avoid inhalation of combustion products
Personal precautions: Evacuate unprotected personnel, ventilate area, avoid breathing vapors, put on suitable protective equipment
Environmental precautions: Prevent entry into waterways, soil, and drains
Methods for Cleanup: Absorb with inert material like sand or vermiculite, place collected material in tight containers for disposal, wash spill site thoroughly after material pickup
Handling: Use only with adequate ventilation, avoid contact with skin, eyes, and clothing, keep away from heat and ignition sources, ground and bond containers when transferring
Storage: Store in a cool, dry, well-ventilated place in tightly closed, labeled containers, keep separate from oxidizing agents, acids, and bases, protect from direct sunlight
Occupational Exposure Limits: Values set by local authorities vary, recommendations generally suggest working below 5 ppm for vapor
Engineering Controls: Use fume hoods or local exhaust ventilation for laboratory handling, maintain negative pressure in storage areas
Personal Protection: Wear chemical goggles or face shield, impervious gloves, lab coat or apron, use a respirator in cases of insufficient ventilation, wash thoroughly after handling
Molecular Weight: 107.15 g/mol
Boiling Point: About 144–146°C
Melting Point: -5°C
Vapor Pressure: Moderate at room temperature
Solubility: Miscible with most organic solvents, slightly soluble in water
Flash Point: Around 38°C (closed cup)
Density: 0.925 g/cm³ at 20°C
Odor Threshold: Detection begins around 0.3 ppm
Appearance: Clear to pale yellow liquid
Chemical Stability: Stable under recommended handling conditions, sensitive to light and air in some cases
Reactive With: Strong oxidizing agents, acids, acid chlorides
Hazardous Decomposition Products: Releases nitrogen oxides and carbon monoxide during thermal decomposition or fire
Hazardous Reactions: May react violently with certain acids or strong oxidizers
Routes of Exposure: Ingestion, inhalation, skin and eye contact
Acute Toxicity: Oral LD50 in rats reported as 215 mg/kg, indicating moderate toxicity, inhalation LC50 (rats, 4h) ranges around 700 ppm
Chronic Effects: Central nervous system depression, liver and kidney injury observed in animal studies after repeated exposure
Irritation/Corrosiveness: Causes serious eye and skin irritation on contact, vapor causes respiratory discomfort
Sensitization: Data insufficient, rare reports of skin sensitization
Mutagenicity/Carcinogenicity: No clear evidence of carcinogenicity, mutagenicity data limited
Toxicity to Aquatic Life: Harmful to aquatic organisms, fish LC50 (96h) values for similar pyridine compounds fall in the range of tens to hundreds of mg/L, indicating moderate risk
Persistence and Degradability: 2,4-dimethylpyridine resists rapid breakdown in water, lingering for weeks under some conditions
Bioaccumulation: Potential to bioaccumulate is moderate based on partition coefficients
Mobility in Soil: Tends to move through sandy soils and may leach to groundwater
Other Effects: Breakdown can lead to formation of more toxic by-products in the environment under certain conditions
Procedure: Dispose of as hazardous chemical waste, follow local, regional, and national guidelines
Methods: Incineration in approved facilities, avoid discharge into sewers, waterways, or soil
Container Disposal: Triple rinse containers, puncture and deliver to approved waste facility
UN Number: UN 2313
Hazard Class: Flammable liquid
Packing Group: III
Transport Hazards: During transit, keep well secured, upright, away from food and incompatible materials, ensure labels and hazard signs remain visible
Special Precautions: Avoid extreme temperatures, restrict access during loading and unloading
OSHA Status: Listed hazardous chemical due to toxicity and flammability
TSCA Inventory: Listed
DSL/NDSL (Canada): Included in chemical inventories
SARA Title III: Potential release subject to reporting as a hazardous substance in case of significant spill
Workplace Labeling: Labels must communicate risks, including toxicity and flammability icons, and be present on all containers
