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Chemical name: 1,3-Dioxolane
Common use: Solvent in industrial, chemical, and pharma processes
Other identifiers: CAS number 646-06-0
Main health risks: Vapors can irritate the respiratory tract, exposure through skin may cause redness or dryness, and serious inhalation can trigger dizziness or headaches due to central nervous system effects
Flammability: Catches fire easily, giving off flammable vapors at room temperature
Eye danger: Splashing in eyes leads to intense stinging, possible vision disturbances
Chronic exposure: Extended contact heightens risk of dermatitis, organ damage has not often been linked but prolonged mishandling may change that
Main component: 1,3-Dioxolane, usually over 95% purity
Other constituents: Trace water, possible light stabilizers depending on source
Inhalation: Step into fresh air, loosen tight clothing, rest until symptoms settle, seek doctor if breathing gets difficult
Skin contact: Wash with running water, soap if available, remove contaminated clothes along the way
Eye contact: Rinse with water for fifteen minutes, blink to help clear substance, medical help if sight blurs or burning won’t quit
Ingestion: Rinse mouth and avoid forced vomiting due to risk of aspiration; hospital visit may be needed if larger amounts ingested
Extinguishing methods: Use foam, dry chemical powder, carbon dioxide for flames
Hazards during fire: Burning releases toxic smoke, carbon monoxide, unidentified organic fumes
Protective advice: Fire teams wear full gear and self-contained breathing masks, avoid breathing burning product fumes, cool nearby tanks with water even if they aren’t leaking
Personal precautions: Evacuate area for vapor build-up, wear rubber gloves, goggles, and organic vapor respirators
Containment: Avoid drainage into sewers or waterways, sweep or mop with inert absorbent material
Clean-up: Shovel into containers with secure lids, ventilate the area thoroughly
Safe handling advice: Work with good ventilation, wear protective gear at all times, avoid inhaling mist or vapor, never smoke nearby
Storage tips: Keep in cool, dry, ventilated place, away from heat, sparks, or direct flame, store in tightly closed containers made of material that won’t corrode
Recommended limits: No established OSHA or ACGIH exposure limit, best to use at the lowest exposure possible
Personal protective equipment: Splash-proof goggles, chemical-resistant gloves such as nitrile, coveralls for body, approved organic vapor respirators if air monitoring shows vapors above safe levels
Engineering controls: Fume hoods and local exhaust needed in confined spaces
Hygiene: Wash hands before breaks or eating, change clothes if splashed, clean spills as soon as possible
Appearance: Colorless liquid
Odor: Mild, somewhat ether-like scent
Boiling point: Around 78°C
Melting point: -95°C
Vapor pressure: Moderate, so vapors build up fast
Solubility: Easily mixes with water and organic solvents
Flash point: Near -1°C, so fire risk is high even at room temp
Density: About 1.06 g/cm³
Chemical stability: Stays stable in closed systems, can degrade if exposed to strong acids or oxidizers
Reactivity: Strong oxidizers spark reactions, acid splits open the dioxolane ring leading to potential runaway heat
Hazardous breakdown: Releases harmful gases like carbon monoxide on strong heat or burning
Acute effects: Can cause headaches, drowsiness, eye and skin irritation even with short exposure
Chronic effects: Some animal studies find kidney or liver changes at very high doses; no cancer listing from IARC or NTP
Sensitization: Not found to cause serious allergies
Absorption routes: Inhaled vapor, skin splash, swallowing by mistake
Environmental fate: Evaporates into air quickly, dissolves easily in water
Toxicity to organisms: Aquatic species handle diluted dioxolane, but bigger spills start cutting into gill function and survival rates
Degradation: Sunlight and microbes break down dioxolane within weeks under the right conditions, but runoff in groundwater can stick around for months if the area lacks enough bacteria or sunlight
Disposal method: Incinerate in approved chemical incinerators if possible, or consign to hazardous waste operators who specialize in solvents
Never pour down drains: Dioxolane fouls water and sewer systems, may explosively react with acids in wastewater treatment
Container disposal: Triple rinse with water or alcohol, puncture to prevent reuse, then treat as chemical waste
Shipping class: Flammable liquid for both road and marine routes
Packaging needs: Leak-proof cans or drums designed for strong solvents
Handling precaution: Label and segregate from acids and oxidizers during transit, secure so no rolling, heating, or dropping occurs during loading
Hazard classification: Listed as flammable and possibly hazardous to aquatic life under many national chemical hazard codes like GHS
Restrictions and labeling: Requires flammable warnings on shipments and in any workplace container labeling system
Use and disclosure: Employers must keep records of storage and use, train staff in handling, and show where MSDS is kept
