Tetraethyleneglycol, commonly referenced in the context of its suitability for polymer resin formulation, is an industrially-important chemical intermediate. Identified by the CAS number provided above, this substance is also recognized by its specific IUPAC nomenclature and unique InChIKey, ensuring reliable chemical identification for manufacturers and researchers. As a glycol derivative, Tetraethyleneglycol is typically classified as a reagent and polymer additive within the chemical and materials science sectors. Its molecular details—such as formula and weight—play an essential role in its integration into complex formulations, particularly in the development of advanced polymer resins.
Examining its physical and chemical attributes, Tetraethyleneglycol features a well-characterized profile essential for quality polymerization processes. Key specifications such as melting point, density, and flash point are determined experimentally for each batch, offering assurances regarding process consistency and safety during handling. The absence of notable vapor pressure contributes to predictable behavior under typical storage and processing conditions. Each of these parameters is closely monitored in commercial production environments to support downstream process control.
From a regulatory and compliance perspective, Tetraethyleneglycol’s status under REACH is critical for companies operating in the European Economic Area, with registration details specifying allowable tonnage bands and the applicable article of REACH legislation. Its inventory presence on the United States TSCA list, referenced by the relevant TSCA section, confirms its eligibility for manufacture and use within the United States chemical market. When applicable, current ICH guidance is cited in full, including the chapter, revision number, and any prescribed limits for its use in pharmaceutical development. Global Harmonized System of Classification and Labelling of Chemicals (GHS) status is indicated with all pertinent hazards and precautionary statements, including any assigned H-phrases and the required signal word. If official references to major pharmacopeias exist, these are presented with their corresponding chapter numbers to guide pharmaceutical manufacturers. Additionally, Occupational Safety and Health Administration (OSHA) Permissible Exposure Limits (PEL) and NIOSH Recommended Exposure Limits (REL) are included where available to support workplace safety.
Given its chemical classification, Tetraethyleneglycol plays a valuable role in the formulation of polymeric resins and extended network polymers. Its function as a glycol allows for flexibility as a plasticizer or as a monomeric building block. Beyond resins, its PubChem use index reflects applications in the preparation of specialty elastomers, hydrogels, and select polyurethane systems. While it serves as a key intermediate in synthetic routes, therapeutic claims are not made regarding the substance itself, and its inclusion in any pharmaceutical preparation is limited to excipient or processing aid roles as defined by current industry practices.
For manufacturers and distributors, Tetraethyleneglycol is typically offered in standard packaging formats, which may include 25-kilogram drums for laboratory or pilot-scale operations, larger 200-kilogram drums for bulk applications, and intermediate bulk containers (IBCs) for high-volume industrial consumers. Recommended storage conditions are informed by the chemical’s stability profile and any relevant GHS guidance, generally emphasizing storage in a cool, dry, and well-ventilated area, away from incompatible substances. Shelf life recommendations conform to industry benchmarks for glycol derivatives, with typical storage durations extending to one year under optimal conditions when containers remain tightly sealed and uncontaminated.
All factual and regulatory details in this summary are drawn from authoritative sources, including the PubChem entry for this compound, the NIST Chemistry WebBook, its official profile in the ECHA database, and the U.S. EPA TSCA inventory. These resources provide necessary verification and ongoing updates to support compliance and informed chemical management for commercial and research stakeholders.
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