2-Nitrophenetole, identified by CAS number {cas_number}, is a key aromatic ether intermediate frequently utilized in the production of dyes and agrochemicals. Its molecular formula is {molecular_formula}, corresponding to a molecular weight of {molecular_weight}. The IUPAC name is {iupac_name}, and its unique chemical structure is confirmed by the InChIKey {inchikey}. Recognized as a versatile chemical intermediate, 2-Nitrophenetole serves an essential role in driving downstream chemical transformations, particularly in the synthesis of colorants and active agrochemical ingredients.
Regarding its physical and chemical specifications, 2-Nitrophenetole exhibits characteristic properties that support its suitability for industrial processes. The boiling and melting points, density, flash point, and vapor pressure values define its operational safety parameters and handling protocols. These data help manufacturers assess storage requirements and determine safe transport conditions during bulk processing.
Compliance with relevant regulatory frameworks is fundamental for the responsible manufacture and distribution of 2-Nitrophenetole. Its REACH registration status, including the applicable article number and tonnage band, ensures transparency for European customers and demonstrates adherence to environmental and human health standards. The chemical's listing under the US TSCA inventory, referenced with the specific section, confirms that it has been reviewed and accepted for commercial distribution within the United States. Any applicable ICH guidelines, with full codes and revisions, offer critical information for pharmaceutical intermediates, such as limits on residual impurities or process contaminants. Detailed GHS hazard classifications outline the required precautionary statements, signal words, and hazard phrases, all of which inform safe handling and mandatory workforce training. Pharmacopeia references, especially chapter numbers when relevant, signify whether the compound meets specific quality requirements for use in regulated sectors. When available, OSHA Permissible Exposure Limits and NIOSH Recommended Exposure Limits provide additional benchmarks for occupational health protections.
The industrial significance of 2-Nitrophenetole lies in its applications as an intermediate for synthesizing a broad range of azo and nitro dyes, which find use in textiles, printing inks, and plastics. In agrochemical development, this molecule is introduced at strategic points in the synthetic sequence to create specific herbicides, fungicides, or insecticides. Its aromatic ether structure offers chemical stability and reactivity, making it a preferred building block for complex molecule assembly. For drug synthesis, 2-Nitrophenetole serves as a precursor in certain active ingredient pathways, though it is not itself therapeutically active.
To meet industry expectations, 2-Nitrophenetole is typically shipped in robust packaging formats, such as 25-kilogram or 200-kilogram drums and intermediate bulk containers (IBCs). Recommended storage calls for a cool, dry, and well-ventilated environment, with specific attention to the guidance set forth by the GHS stability and hazard statements. As with most aromatic ether intermediates, industry practice supports a shelf life of up to two years when stored under these controlled conditions.
The information presented here draws upon authoritative sources, including PubChem at https://pubchem.ncbi.nlm.nih.gov/compound/{cid}, NIST Chemistry WebBook at https://webbook.nist.gov/cgi/cbook.cgi?Name={cas_number}, the European Chemicals Agency at {echa_url}, and the EPA TSCA Inventory available at https://www.epa.gov/tsca-inventory.
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