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Homo-L-Tyrosine, Hydrobromide

    • Product Name Homo-L-Tyrosine, Hydrobromide
    • Alias homo-l-tyrosine-hydrobromide
    • Einecs 242-970-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    702250

    Product Name Homo-L-Tyrosine, Hydrobromide
    Cas Number 13472-20-1
    Molecular Formula C10H14NO2·HBr
    Molecular Weight 276.14 g/mol
    Appearance White to off-white powder
    Melting Point 210-216°C (dec.)
    Solubility Soluble in water
    Purity Typically ≥98%
    Storage Condition Store at 2-8°C
    Synonyms 4-(2-Aminoethyl)phenylalanine hydrobromide
    Ec Number 236-633-7
    Application Used in biochemical research

    As an accredited Homo-L-Tyrosine, Hydrobromide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 1g Homo-L-Tyrosine, Hydrobromide is packaged in a sealed amber glass vial with tamper-evident cap and clear labeling.
    Shipping Homo-L-Tyrosine, Hydrobromide is shipped in tightly sealed, chemical-resistant containers to ensure stability and prevent moisture absorption. The package is clearly labeled with hazard information and handled as per standard regulations for non-hazardous biochemical substances. Shipping is typically expedited with temperature control if required and includes all necessary documentation for safe handling.
    Storage Homo-L-Tyrosine, Hydrobromide should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at 2-8°C (refrigerator). Avoid exposure to strong oxidizing agents. Ensure proper labelling and secure storage away from incompatible materials to maintain its stability and prevent contamination or degradation.
    Application of Homo-L-Tyrosine, Hydrobromide

    Applications of Homo-L-Tyrosine, Hydrobromide in Industrial Manufacturing

    As a direct manufacturer with precision synthesis capabilities, we supply Homo-L-Tyrosine, Hydrobromide for critical downstream sectors that depend on advanced amino acid derivatives. Our production supports exacting customer requirements and process integration demands in regulated industrial environments.

    1. Active Pharmaceutical Ingredient (API) Synthesis for Peptide Drugs

    Peptide drug manufacturers incorporate this raw material during the solid-phase peptide synthesis (SPPS) of novel and modified amino acid-based APIs. Its controlled substitution profile allows pharmaceutical chemists to extend peptide chains with non-canonical residues, tuning bioactivity and metabolic stability for targeted therapies. Batch records typically document controlled raw material input, while analytical QC verifies purity and sequence incorporation before downstream formulation.

    Industry compliance standards

    • ICH Q7A Good Manufacturing Practice (GMP) for APIs
    • United States Pharmacopeia (USP) standards—where relevant for peptide raw substances
    • European Pharmacopoeia, Monograph 2034 (Peptide APIs—applicability for raw material traceability)
    • FDA 21 CFR Part 211 (Finished Pharmaceuticals GMP)

    Typical usage ratio

    • 0.2–2.5 mol% of total amino acid input, adjusted for target peptide sequence and length
    • Process chemists may increase ratio for non-standard residue positions requiring enhanced stability or function
    • Low level spiking for cGMP process validation runs (<0.5 mol%)
    • Up to 5% in lead optimization for early-stage drug discovery screening

    Downstream process integration

    • Inline coupling during SPPS cycle, after protected group deprotection
    • Utilized at the residue extension stage prior to resin-bound peptide cleavage
    • Post-synthetic HPLC purification of crude peptides containing the amino acid derivative
    • Quantitative transfer to peptide drug intermediate formulation (lyophilization, fill/finish)

    Final product types

    • Injectable peptide drugs (oncology, metabolic disorders)
    • Custom peptide fragments for targeted therapy APIs
    • Specialty oligopeptide intermediates for advanced medicinal research
    • Analytical peptide standards and reference substances

    2. Chemical Synthesis of Chiral Building Blocks for Fine Chemicals

    Chemical synthesis operations utilize this compound as a chiral synthon when constructing complex scaffolds, where the protected amino acid aids in asymmetric induction and ensures predictable stereochemical outcomes. Its hydrobromide salt form offers precise stoichiometry and solubility for robust organometallic or enzymatic coupling procedures, directly impacting reaction control in the fine chemicals value chain.

    Industry compliance standards

    • ISO 9001:2015 Quality Management for chemical manufacturing
    • REACH (EC) No 1907/2006 compliance for safe manufacture and downstream use
    • GHS/CLP Regulation (EC) 1272/2008 (classification and labeling in chemical handling)
    • Responsible Care management system (ICCA voluntary standards)

    Typical usage ratio

    • 1.0–3.5 molar equivalents relative to the target core structure
    • Adjusted downward (to 0.6 eq.) for catalytic chiral induction techniques
    • Higher ratios (up to 5 eq.) for end-capping or selective functionalization protocols
    • Batch vs. continuous flow processing may alter proportion to match residence time and reagent costs

    Downstream process integration

    • Reagent addition to the main reactor during nucleophilic substitution or acylation
    • Intermediate protection/deprotection stages in multi-step synthesis
    • Isolation via solvent extraction and crystallization, especially for chiral quality assurance
    • Transfer of isolated chiral intermediates for downstream derivatization

    Final product types

    • Enantiomerically pure intermediate chemicals
    • Custom fine chemical building blocks for pharmaceutical, agrochemical, or materials industries
    • Ligands for asymmetric catalysis
    • Chiral auxiliaries for specialty organic synthesis

    3. Diagnostic Reagent Manufacturing for Life Science Instruments

    Producers of in vitro diagnostic kits and biosensor reagents employ this raw material as a performance-modifying component in enzyme substrates and calibration solutions. Its molecular structure offers diagnostic assay developers an option for creating signal amplification substrates or molecular controls that match biological reactivity, supporting the quality control of clinical diagnostic platforms such as immunoassays and mass spectrometry methods.

    Industry compliance standards

    • ISO 13485:2016 (Quality Management for Medical Devices)
    • In Vitro Diagnostic Regulation (IVDR) EU 2017/746
    • US FDA 21 CFR 820 (Quality System Regulation for diagnostics)
    • CLSI EP protocols (Clinical and Laboratory Standards Institute—assay validation)

    Typical usage ratio

    • 0.005–0.1% w/v in calibration buffers and assay substrates
    • Up to 0.5% for high-sensitivity detection formats
    • Level may decrease to 0.002% in control solutions where background signals require minimization
    • Lot-specific optimization depending on platform and instrument sensitivity

    Downstream process integration

    • Buffered formulation blending during diagnostic kit reagent preparation
    • Solid-phase immobilization when creating calibration standards
    • Filling and lyophilization steps for stabilized diagnostic controls
    • Final packaging in multi-component IVDR-compliant test kits

    Final product types

    • Clinical chemistry in vitro diagnostic reagents
    • Biosensor calibration and validation standards
    • Automated analyzer consumable cartridges
    • Enzyme-linked assay kits and reference substrates

    4. Nutritional Research—Special Amino Acid Formulation for Experimental Diets

    Institutes and contract manufacturers preparing specialized animal or cell culture diets utilize this compound to formulate defined amino acid pools for research studies in metabolic regulation and protein synthesis. The unambiguous configuration and salt purity suit published protocols requiring L-configuration consistency, while highly controlled blending enables precise adjustment of tyrosine derivatives for experimental validation.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals (Section 4, Health Effects, for dietary studies)
    • Good Laboratory Practice (GLP) principles (OECD, FDA 21 CFR Part 58)
    • Association of American Feed Control Officials (AAFCO) requirements, where applicable for animal research
    • Institutional Animal Care and Use Committee (IACUC) dietary protocol approvals

    Typical usage ratio

    • 0.001–0.02% of total feed or medium composition for animal studies
    • Variable ratio (from trace up to 0.05%) for amino acid replacement or metabolic tracer protocols
    • Higher concentrations up to 0.1% for short-term metabolic pulse labeling in cell culture
    • Downward adjustment based on organism sensitivity and protocol endpoints

    Downstream process integration

    • Dry blending with bulk amino acid premix before pelleting or extrusion (animal diets)
    • Sterile filtration and aqueous dosing for liquid cell culture media
    • Sampling during premix QC testing to confirm isotopic or enantiomeric content
    • Feedstock measurement and recording for regulatory study traceability

    Final product types

    • Custom rodent or livestock experimental feeds
    • Defined amino acid-based cell culture media
    • Metabolic labeling kits for in vivo and in vitro research
    • Reference feeds for nutrition-based toxicity and safety studies
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    Certification & Compliance
    More Introduction

    Homo-L-Tyrosine, Hydrobromide: A closer look at a key chemical building block

    Learning about chemicals can feel like navigating a maze at times, especially if you aren’t a chemist working hands-on in a lab every day. But every now and then, a compound pops up that seems to get a bit of extra attention. Homo-L-Tyrosine, Hydrobromide ranks as one of those. Not because it is a household name, but because its role in research, manufacturing, and supplementation keeps showing up in places that matter to a surprisingly wide group of professionals.

    The model and basic characteristics

    Folks sometimes get tripped up by chemical names. The “Homo” part signals a molecule with an expanded carbon backbone compared to familiar amino acids like tyrosine. The “L” hints at the left-handed configuration, which matches what living systems use. “Hydrobromide” points to the salt form, meaning a hydrobromic acid has been used to stabilize the molecule—this helps keep it shelf-stable and easy to work with. Many labs call its model “CAS: 556-02-5”, useful for tracking purity and source in academic or pharmaceutical environments.

    You know, I remember seeing this compound on a shelf in a life science lab and thinking how tiny differences in a molecule’s structure can shift its applications in meaningful ways. In fact, that extra carbon in Homo-L-Tyrosine gives chemists a neat workaround: it expands the potential for modifications in peptide synthesis, which is vital if a researcher wants to mimic or block certain biological processes. Distilling this down, the compound opens doors where regular L-Tyrosine sometimes can’t reach.

    Reasons researchers and professionals care

    There’s a reason a high-purity offering matters here—contaminants can ruin an experiment. What really sets Homo-L-Tyrosine, Hydrobromide apart from your everyday amino acids is its role as a specialty precursor. You’ll find it in the toolkit of those working on new pharmaceuticals, designer peptides, or just those trying to unlock new kinds of sensor technology. In some advanced research, swapping this for routine tyrosine lets investigators measure how subtle changes in side-chain length affect enzyme activity, receptor binding, or even the behavior of synthetic polymers.

    Development routes for new therapies often rely on small shifts in molecular structure. When people in industry or academia consider homo-amino acids like this one, they’re often interested in building new analogues for medicinal chemistry, exploring new variants for drug candidates, or trying to understand the role of tyrosine in neural compounds. I’ve talked with grad students who spend months troubleshooting reactions that hinge on purity or solubility—the Hydrobromide form shaves time off prep because it’s moisture-stable, handles predictably, and dissolves in water better than the raw base form.

    Where Homo-L-Tyrosine, Hydrobromide fits in peptide and pharmaceutical work

    Synthetic peptides play a huge part in everything from vaccine development to creating better imaging agents. Most projects start by stringing amino acids together in a specific sequence. Adding Homo-L-Tyrosine through solid-phase peptide synthesis lets scientists insert a flexible spacer into chains, often changing the biological properties in subtle but important ways. Peptides with extra methylene groups—like the one in homo-tyrosine—sometimes resist enzymatic breakdown or bind differently to target receptors. The pharmaceutical industry looks for these alterations to release new therapies or diagnostics with longer-lasting effects.

    There’s also this practical reality: researchers need products that are easy to quantify and store. Hydrobromide salt forms shine for this. They arrive as white crystalline solids, track easily in solution, and resist clumping from environmental moisture. Even if you’re running a big synthesis campaign or scaling up, minor differences like this can mean fewer headaches and less waste.

    How usage translates into real-world projects

    Moving beyond bench science, Homo-L-Tyrosine, Hydrobromide sometimes features in nutrition studies, but mainly as a tool rather than a treatment. Rigorous data hasn’t confirmed it offers unique benefits over regular tyrosine in people, so clinical use stays rare. What it always delivers is control—by using this molecule, labs run comparative studies that map how analogues perform in enzyme assays, cell cultures, and animal models. Over time, this kind of research points the way toward smarter drugs or more robust biomaterials.

    Unlike some chemicals that vanish into the background, Homo-L-Tyrosine, Hydrobromide’s workhorse reputation grows when results matter most. Pharmaceutical formulation teams use it to create cleaner intermediates, biotechnologists tinker with it to probe protein function, and analytical chemists trust its stable form to achieve tighter controls on purity. I’ve seen projects stall for weeks when using bulk commodity amino acids full of byproducts, so the confidence a well-characterized Hydrobromide salt provides isn’t academic—it’s practical.

    Comparing with other forms and analogues

    Standard tyrosine feels almost generic these days, available in bulk for food and supplement blends. What makes Homo-L-Tyrosine, Hydrobromide distinct isn’t just an extra carbon; the real difference comes in how its backbone tweaks the shape of finished peptides, often shifting how they fold or interact with biological surfaces. This ranks as a big deal if you’re developing new therapies, because tiny changes can flip biological activity from zero to one. Peptide researchers count on Homo-L-Tyrosine to test structure-activity relationships that regular tyrosine simply can’t address.

    There’s also a practical angle in solubility, handling, and documentation. Raw Homo-L-Tyrosine must go through additional processing to match the shelf life and ease of weighing or measuring offered by the Hydrobromide salt. In regulated industries, documentation supporting traceability and characterization matters for safety and reproducibility. Hydrobromide salt products almost always provide clearer paperwork, which streamlines audits and simplifies repeat ordering.

    Insights from production and scalability

    Industry keeps pushing for tighter specs, cleaner performance, and more reliable outcomes—whether the target sits in pharmaceuticals, specialty polymers, or diagnostic agents. High-purity Homo-L-Tyrosine, Hydrobromide answers this call thanks to scalable synthesis routes. The best supplies usually come from multi-step routes, often involving protected intermediates that strip away unwanted side products. You don’t hear about this on marketing sheets, but it makes a difference in cost structure and lot-to-lot consistency.

    Labs running continuous or contract manufacturing lines benefit here. The hydrobromide salt handles well in large reactors, ships safely, and resists environmental changes. Teams working under Good Manufacturing Practice (GMP) get much more than a raw input—they count on this predictability to deliver quality batches without holdups from unexpected impurities. Whether making grams or kilos, the difference in process flow compared to older or less stable forms shows up in efficiency metrics.

    What’s driving adoption, and what could improve?

    Demand for rare amino acid derivatives has been climbing, especially with genomics and proteomics generating more intricate questions for life science. Simply put, chemical flexibility brings competitive advantages for any lab or firm eager to leap ahead in bioengineering, drug trials, or custom peptide design. Investments follow the trail of high-value analogues, and Homo-L-Tyrosine, Hydrobromide slots into that scene as a go-to variant for those who can’t get the same answers with standard building blocks.

    Truth be told, sourcing challenges and high prices sometimes hold back adoption for smaller-scale users or newer research groups. Producers who commit to transparency, detailed analytical data, and dependable logistics end up with loyal customers because nobody wants to gamble on a key input that might vary by batch. I’ve seen first attempts at scale-up go sideways due to missed documentation or unexpected shelf-life issues. This reinforces the need for clear, experience-based supplier relationships.

    From an improvement standpoint, sharper certification protocols and third-party validation help build confidence in the marketplace. I’d like to see broader inter-lab collaboration, where scientists from different backgrounds publish open-access QC data sets. There’s a lot to gain if suppliers and customers agree on standardized libraries for NMR, HPLC, and elemental analyses. This not only boosts transparency, but speeds up the process for anyone looking to move from bench to pilot scale.

    Safety, environmental footprint, and responsible handling

    Anyone in a lab will tell you—safety habits make or break careers. With Hydrobromide salts, including Homo-L-Tyrosine, personal experience reminds me they are stable but can be irritating in dust form. Gloves, goggles, and well-ventilated areas aren’t just checkboxes—they’re day-to-day reality. While these compounds don’t usually present extreme hazards, improper handling still creates avoidable risks. Most professionals store them in sealed, labeled containers, away from humidity and acidic fumes, which ensures the product remains viable between uses.

    Modern manufacturers care about how their production impacts the world outside the lab. Making amino acid derivatives with minimal waste matters more than ever. Some producers invest in closed-loop systems for solvent recovery or switch to greener reagents that remove persistent contaminants before discharge. Progress in this area sometimes follows stricter regulation, sometimes comes from internal sustainability goals set by leadership teams who want to leave a cleaner chemical legacy.

    For buyers, picking a supplier that shares details about their environmental controls makes sense in the long run. As someone who worked in a research supply office, I remember how the request for “green chemistry” credentials ramped up as soon as clients started auditing lab footprints more closely. Over time, this nudges the market toward better practices, leaving less of a mess for future generations.

    Learning curves and broader benefits

    Nobody picks up a specialty intermediate and masters it overnight. I’ve watched teams new to peptide chemistry struggle through the nuances of weighing, dissolving, and integrating derivatives like Homo-L-Tyrosine, Hydrobromide into their workflows. Once mastered though, the gains show up in tighter experimental controls and sharper results during testing. Teaching newer staff about the quirks of handling hydrobromide forms—like avoiding condensation around the jar or using analytical balances for the needed precision—saves time and hassle over hundreds of experiments.

    Colleagues often share practical tips through hallway chats or IP-protected protocols that don’t always make it to scientific papers. Over time, this trust in experience builds a support network where best practices travel quickly. Some suppliers host webinars on trouble-shooting peptide synthesis, focusing on common pain points around solubility or reaction cleanup. Groups that take part more often report fewer failed experiments and wasted materials, which builds momentum toward better science—everybody wins when knowledge moves freely.

    Potential barriers and common misconceptions

    The main misconceptions about Homo-L-Tyrosine, Hydrobromide usually spring from lumping it together with more familiar dietary amino acids. Folks sometimes expect it to show up in supplement aisles or as a performance booster, yet the real value lies in precision research, not consumer nutrition. It isn’t metabolized the same way as tyrosine in the body, and most of its chemical advantages emerge during synthesis, not in human physiology.

    Cost sometimes scares off labs that haven’t worked with analogues before. Specialty derivatives cost more than commodity amino acids. Yet what they deliver in control and experimental flexibility more than covers the difference when failure of a large batch is on the line. Upfront training, realistic safety protocols, and partnerships with suppliers that understand regulatory landscapes keep mistakes scarce.

    Looking ahead: Next steps for users and suppliers

    The market for compounds like Homo-L-Tyrosine, Hydrobromide keeps expanding, especially as interdisciplinary science blurs the lines between biology, chemistry, and materials science. More university labs integrate analogues into first- and second-year curricula, pushing students to think beyond classic monomers. The next decade will likely bring even more focus on the interfaces: how these altered building blocks drive better sensors, enable more targeted drugs, or produce safer, more stable materials in everything from healthcare to industrial settings.

    For those considering adoption, investing in solid documentation and sample runs pays off. Lab leadership who create space for trial-and-error, paired with honest feedback from early adopters, gain a reputation for reliable results. Suppliers who respond promptly to questions, support transparency, and back up their QC data with experience-based advice will continue to stand out.

    In my own path working with specialty chemistries, the projects that succeeded most often shared one trait—a willingness from every link in the chain to adapt as new use cases or sourcing realities evolved. From academic labs chasing new protein targets, to industrial teams developing next-gen formulations, the ability to react quickly to feedback turns specialty molecules from theoretical curiosities into workhorses for real-world impact.

    Summary thoughts on value and direction

    Homo-L-Tyrosine, Hydrobromide doesn’t make headlines outside of science and manufacturing, but plenty of innovation depends on consistent, high-purity intermediates like it. Every successful drug, every diagnostic tool, and every experimental breakthrough riding on synthetic peptide technology owes plenty to the scientists who dig deep into the details of chemical structure and sourcing.

    Experience has shown me that small differences in molecular scaffolding make huge impacts down the line. With markets steering toward engineered molecules that stretch what’s possible, tools like Homo-L-Tyrosine, Hydrobromide move out of the niche and into an essential role. By investing in reliable sources, sharing know-how, pushing for greener production, and demanding robust documentation, professionals in research and manufacturing do more than run their own projects—they set stronger foundations for the next generation of discovery.