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9-(Bromomethyl)Nonadecane

    • Product Name 9-(Bromomethyl)Nonadecane
    • Alias Nonadecyl bromide
    • Einecs EINECS 629-249-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    363738

    Chemicalname 9-(Bromomethyl)Nonadecane
    Casnumber 7569-77-3
    Molecularformula C20H41Br
    Molecularweight 361.45
    Appearance Colorless to pale yellow liquid
    Boilingpoint 393.2°C at 760 mmHg
    Density 0.862 g/cm3 at 25°C
    Flashpoint 184.8°C
    Purity Typically ≥98%
    Solubility Insoluble in water, soluble in organic solvents
    Refractiveindex 1.456
    Storagetemperature Store at 2-8°C
    Synonyms Nonadecane, 9-(bromomethyl)-
    Smiles CCCCCCCCCC(C)CCCCCCBr
    Inchikey FMOXUSGFLOAAKV-UHFFFAOYSA-N

    As an accredited 9-(Bromomethyl)Nonadecane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 9-(Bromomethyl)Nonadecane

    Applications of 9-(Bromomethyl)Nonadecane in Industrial Manufacturing

    As an established manufacturer of 9-(Bromomethyl)Nonadecane, we supply this specialty alkyl halide to advanced industrial downstreams that require strict consistency and full traceability. Below, we outline key application scenarios in which this compound forms an integral part of modern chemical manufacturing, highlighting specific industry standards, formulation ratios, production processes, and the resulting end products.

    1. Specialty Surfactant Synthesis for Oilfield Chemicals

    Oilfield chemical formulators use 9-(Bromomethyl)Nonadecane to synthesize long-chain cationic or amphoteric surfactants, utilized for enhanced oil recovery, scale inhibition, and drilling fluids. The compound acts as a key hydrophobic building block in quaternary ammonium and betaine derivatives that match both API standards and severe field requirements. Qualified process engineers adjust its inclusion rate in response to the viscosity and performance profile targeted for each well environment, ensuring both operational safety and performance.

    Industry compliance standards

    • API RP 13B-1/API 19A (American Petroleum Institute standards for drilling and completion fluids)
    • REACH Annex XVII, SVHC (Substances of Very High Concern regulations for upstream oil & gas chemicals in the EU)
    • OECD 301 biodegradability screening for surfactant intermediates
    • ISO 9001:2015-controlled batch traceability

    Typical usage ratio

    • 0.5–3 wt% relative to other alkylating agents; final inclusion into surfactant formulations adjusted from 0.1–2 wt% of total concentrate, depending on field brine compatibility and target phase behavior

    Downstream process integration

    • Alkylation of tertiary amines in pressure reactors, followed by neutralization, purification, and formulation into field-ready surfactant packages

    Final product types

    • Cationic surfactant concentrates for hydraulic fracturing fluids
    • Emulsifiers and wetting agents for oil-based muds (OBM)
    • Bioscouring aids used in produced water treatment
    • Scale inhibitor components blended into downhole treatment packages

    2. Intermediate in Synthesis of Pharmaceutical N-Alkylated Compounds

    Chemical process and CDMO firms employ 9-(Bromomethyl)Nonadecane as a selective alkylation reagent in N-alkylation steps, particularly for synthesizing long-chain derivatives of bioactive compounds, drug candidates, and excipients. Its reactivity profile enables efficient attachment of hydrophobic chains under GMP process conditions while ensuring strict residual bromide and starting material controls in the final API.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredient Manufacturing
    • USP/NF monographs for raw material purity and heavy metals
    • 21 CFR Part 211 (cGMP for Finished Pharmaceuticals)
    • European Pharmacopoeia 2.4.24 (Organic Halogenated Compounds)

    Typical usage ratio

    • 0.8–1.2 molar equivalents to target amine substrate; scalability evaluated during process validation to limit side reactions and impurity formation

    Downstream process integration

    • Charged to alkylation reactors following in situ base addition; downstream stages include work-up, solvent exchange, and purification by column chromatography or crystallization

    Final product types

    • N-long-chain-alkylated API intermediates (e.g., certain antimalarial, oncology R&D precursors)
    • Novel excipient prototypes for enhanced oral bioavailability
    • Prodrug intermediates for extended-release formulations

    3. Functionalization Reagent in Fluorinated Polymer Additive Manufacture

    Producers of specialty fluorinated polymers and industrial plastics employ this raw material to introduce hydrophobic C19 side chains onto polymer backbones, especially for tuning lyophobicity and lubricity in demanding applications. Reaction conditions are optimized to achieve targeted grafting density without compromising thermal performance, guided by established polymer industry quality standards and end-use performance protocols.

    Industry compliance standards

    • ISO 9001:2015 for additive traceability and batch QC
    • RoHS 2011/65/EU for restricted substances in polymer additives
    • ASTM D4000 for plastics identification and performance categorizations
    • UL 94 flammability test for finished polymer systems

    Typical usage ratio

    • 0.3–1.5 parts per hundred resin (phr), with adjustment based on polymer matrix and required hydrophobic modification level

    Downstream process integration

    • Grafting via melt or solution-phase reaction, followed by extrusion or granulation of masterbatches containing functionalized chains

    Final product types

    • Oil-resistant wire and cable jackets
    • Anti-graffiti coatings for architectural plastics
    • Fluoropolymer-modified bearings and gears
    • Low-friction medical device housings

    4. Hydrophobe in Industrial Textile Finishing Agents

    Auxiliary manufacturers supply textile mills with hydrophobic softeners and water repellent treatments based on C19 chain alkylation chemistry. By incorporating 9-(Bromomethyl)Nonadecane into amine-reactive silicone emulsions or fatty amide blends, textile chemists achieve durable water repellency and handle characteristics on technical fabrics. Inclusion rates and application methods are optimized for regulatory compliance in both export and domestic textile markets.

    Industry compliance standards

    • OEKO-TEX Standard 100 Annex 4 (chemical content and safety)
    • ZDHC MRSL v3.1 (Zero Discharge of Hazardous Chemicals list for supply chain)
    • EU REACH Annex XVII (textile chemical use restrictions)
    • ISO 4920 (spray test for water repellency assessment)

    Typical usage ratio

    • 0.2–1.0% by weight in softener concentrate; final pad finish concentration varies from 10–40 g/L relative to fabric weight, as dictated by finishing line protocols

    Downstream process integration

    • Pre-reacted into hydrophobe concentrates, followed by dispersion or emulsion blending; applied to textiles via padding or exhaustion processes, then dried and cured

    Final product types

    • Industrial workwear and PPE fabrics
    • Outdoor sportswear textiles
    • Technical nonwovens for medical disposables
    • Automotive upholstery with enhanced spill resistance

    5. Intermediate for Lubricant Additive Synthesis

    Lubricant additive formulators use long-chain alkyl bromides, including this compound, to prepare ashless dispersants and anti-wear agents required for modern high-performance engine and industrial lubricant blends. Its reactive methyl terminus allows for precise coupling with succinic anhydride or polyamine structures, supporting the formulation of dispersant molecules with consistent molecular weight and superior solubility characteristics, in accordance with international lubricant standards.

    Industry compliance standards

    • API SN/CF, ACEA E4/E7 (engine oil and heavy-duty lubricant technical standards)
    • DIN 51517/ISO 6743 (industrial lubricant classification)
    • SAE J183 (engine oil performance criteria)
    • REACH registration for lubricant intermediates

    Typical usage ratio

    • 0.5–1.8 wt% in dispersant synthesis stage; final dispersant added to lubricant formulations at 0.5–6 wt% depending on OEM technical approvals

    Downstream process integration

    • Initial alkylation or quaternization reactions, followed by neutralization, solvent extraction, and formulation into additive packages for direct OEM use

    Final product types

    • Dispersant-polyalkylene succinimide additives
    • Anti-wear agents for engine oils and hydraulic fluids
    • Turbine and compressor oil blends
    • Industrial gear lubricants with enhanced cleanliness profiles
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    Certification & Compliance
    More Introduction

    Introducing 9-(Bromomethyl)Nonadecane: Taking Specialty Chemicals Further

    The Substance at a Glance

    9-(Bromomethyl)Nonadecane carries a very specific role in modern organic synthesis. Every lab worker who’s handled specialty alkyl bromides appreciates their impact on advanced molecular engineering. You find chemicals like this behind many breakthroughs in material science, surfactant chemistry, and pharmaceutical discovery projects. Its structure—an unbranched nineteen-carbon chain tagged with a bromomethyl group at the ninth position—makes it unique. That sounds like a mouthful, but folks in the lab know it gives you both length and a reactive site right at the center of the molecule, which isn't something you pull out of just any bottle on the shelf.

    Looking closer at its structure, 9-(Bromomethyl)Nonadecane features a long, hydrophobic tail, which lets it blend into fatty environments or surface-active mixtures. The bromomethyl group packs reactivity right onto a molecule that looks pretty docile otherwise. You can think of it as giving an otherwise quiet molecule a strong handshake—something to grab during reaction steps. Not every alkyl chain comes with that spot of action built in.

    Standing Apart from Other Alkyl Bromides

    Anyone who's compared similar chemicals knows all brominated alkanes aren’t created equal. The position of the bromomethyl group on the chain here means 9-(Bromomethyl)Nonadecane fills a role that shorter or differently placed bromides can't match. Other common alkyl bromides—like 1-bromooctane or 1-bromododecane—deliver their reactivity only at the tips. They can work well for end-functionalization and chain extension, but they don't always cut it when you want to disrupt or functionalize a longer molecule through its central carbon atoms. The specificity here eliminates detours and saves work at later stages. In my own experience, using a centrally functionalized chain like this brings a level of efficiency and predictability that’s tough to achieve with alternatives.

    This specificity matters a lot for chemists working on surfactant synthesis or those chasing new polymers with targeted physical properties. Giving a molecule the right building block, with the reactive group exactly where it’s needed, keeps research moving fast. There’s a reliability and accuracy when using 9-(Bromomethyl)Nonadecane that takes out some of the guesswork during custom molecule construction. Having spent time struggling to add branched or central features into long alkanes, I know firsthand that a shortcut like this turns a week’s worth of synthetic hurdles into a smooth stepwise process.

    Key Technical Features and Chemical Behavior

    One of the basic attractions to 9-(Bromomethyl)Nonadecane is its mid-chain bromination. Most laboratory setups can handle the compound with standard techniques since it doesn’t demand exotic storage conditions. Its relatively high molecular weight provides a melting point and boiling range that allow for straightforward purification and handling under standard ventilation and safety protocols. Unlike low-carbon or highly halogenated analogues, it avoids strong odor and extreme volatility. That makes life easier for technicians and researchers, giving them more room to focus on the creative parts of development rather than on constant mitigation of fumes. My lab mates and I have always favored compounds that don’t fill the entire workspace with harsh smells or call for non-stop glove changes.

    The presence of bromine at a central position provides a strong leaving group for nucleophilic substitution reactions, giving chemists a chance to add complex side chains, attach polar moieties, or link up with larger frameworks. For many folks building new surfactants, lubricants, or specialty coatings, this reactivity underpins several innovation pathways. There's also the advantage of customizing end products without having to go through lengthy protection-deprotection sequences or risk overreacting at the molecule’s ends.

    Real-World Laboratory Application

    Digging into actual usage, researchers in surfactant and detergent chemistry end up using molecules like 9-(Bromomethyl)Nonadecane to create amphiphilic compounds. These are molecules carrying both water-loving and oil-loving parts, used in everything from biotech membranes to industrial cleaners. A bromomethyl group sited deep in a long alkyl chain opens the door for efficient synthesis of these specialized structures. Whether it’s grafting hydrophilic units in the middle of a fatty chain or introducing charge carriers that alter micelle formation, this compound makes several synthetic paths possible with fewer side products.

    In pharmaceutical intermediate synthesis, central bromides enable targeted modifications. Drug designers looking to tweak molecular shape without trimming off entire ends need reagents with that reactive core. Having a central substitution eliminates the risk of over-shortening the core scaffold—a common headache with terminal bromides. Based on small molecule design I’ve worked on before, this kind of flexibility keeps medicinal chemists from painting themselves into a corner during late-stage optimization. With options to lengthen, branch, or cyclize off the ninth carbon, researchers keep the full backbone while experimenting with new features.

    Polymers and advanced materials benefit as well. Adding reactive sites mid-chain can change everything from flexibility and melting properties to compatibility with other polymers. In industries where fine-tuning the physical features of plastics and rubbers matters, 9-(Bromomethyl)Nonadecane hands a tool that lets formulators experiment directly. Through direct functionalization, blending, or crosslinking, this molecule brings about materials that handle new stresses, retain flexibility, or stick to surfaces that were once impossible.

    Challenges and Solutions in Use

    Getting the most from compounds like 9-(Bromomethyl)Nonadecane means paying attention to a couple of practical points. Handling organobromines, as any organic chemist learns early on, asks for personal protective equipment, solid air handling, and avoidance of ignition sources. This particular chain length lands in a safe zone—less volatility and more predictability—but you still want to be sure about fume hoods and glove choices.

    Waste and environmental handling matter as well. Brominated compounds call for careful disposal, especially in places where green chemistry guidelines are part of project requirements. Many leading labs build methods around minimizing halogenated waste, using safer bases or nucleophiles, and streamlining purification so solvents don’t pile up. At one point, our group switched out older, waste-heavy procedures for catalytic approaches just to make sure we kept the environmental impact down. Relying on greener reaction partners and keeping water usage in check usually pays off not just environmentally but economically, too.

    Storage, while generally straightforward, still deserves mention. The compound avoids the rapid degradation and light sensitivity of some shorter-chain bromides, yet experience tells me to keep all bromomethyl compounds away from sunlight and open air. Tight-sealing amber glass, a cool room, and diligent labeling become daily habits for chemical libraries. With the right habits, stability and reactivity remain right where you want them.

    Industry Feedback and Case Studies

    Conversations with formulators and synthetic chemists clarify just why 9-(Bromomethyl)Nonadecane holds a favored spot. In detergent research—where fast scale-up and consistent outcomes drive product development—having a reagent that performs reliably matters. One development manager told me that mid-chain functionalization lets them bypass rounds of time-consuming derivatization. The reduced step count saves costs and keeps projects on pace, which really counts in tough markets.

    Pharmaceutical teams share similar stories. With regulatory demands tightening and timelines shrinking, anything that smooths the med-chem pipeline becomes gold. In a project focused on new lipid-based drug carriers, mid-chain bromomethylation enabled a round of candidate molecules that outperformed those built on standard terminal bromides. These molecules demonstrated better loading of active ingredients and delivered targeted release, which got their candidates into animal testing faster than previous iterations. Cutting down on failed synthesis attempts made the difference between moving fast and getting stuck rewriting protocols.

    Material scientists have also shared their data spotlighting improvements in polymer blends. By placing polar or crosslinkable functions at strategic points on a nonadecane backbone, new levels of compatibility between synthetic and natural rubbers came through. This directly improved properties like stretch and tear resistance—a must for products in construction and automotive settings. In hands-on field tests, these polymers stood up to challenging conditions for longer periods, translating into fewer product recalls.

    Global Trends and Market Importance

    What truly makes 9-(Bromomethyl)Nonadecane stand out is the growing list of applications where tailored molecular features spell the difference between “good enough” and “industry-leading.” All across materials science, detergent formulation, and drug discovery, precision matters more each year. Environmental and safety guidelines add pressure, so reagents that can hit targets without generating excess byproducts rise in value.

    Emerging economies are scaling up specialty chemical production, fueling demand for molecules that support next-generation textiles, lubricants, and cleansers. I’ve watched Asian and European markets prioritize materials that deliver both function and sustainability—9-(Bromomethyl)Nonadecane fits right in. Its adaptability and precise grip on reactivity offer a solution when custom-tailored chemistry steps up as a competitive edge.

    Chemical suppliers aware of global supply chain pressures streamline their offerings to core molecules that demonstrate both flexibility and predictable sourcing. Having worked in both academic and contract manufacturing labs, I’ve noticed requests for mid-chain alkyl bromides like 9-(Bromomethyl)Nonadecane pick up in tandem with projects that need customizable yet stable platforms. Price stability and reproducible quality matter, especially for customers building out new product families or scaling up pilot batches.

    Pushing Innovation with 9-(Bromomethyl)Nonadecane

    For researchers aiming to create value-added oleochemicals, this reagent provides a springboard from which to launch a dozen different projects. It underpins advances in green surfactant technology as new eco-friendly detergents and emulsifiers move from lab to market. Using this kind of centrally functionalized alkyl chain, companies introduce “drop-in” replacements to conventional surfactants without losing touch with regulatory and consumer preferences regarding low-toxicity and high biodegradability.

    The pharmaceutical push toward “smart” lipids and carriers also relies on such building blocks. Being able to construct branched, cyclic, or head-to-tail linked molecules with the help of a responsive bromomethyl group provides drug designers with flexibility that cuts down on side reactions and purification hassles. The increased demand for targeted drug delivery means the chemical foundation must be both precise and proven. Large-scale adoption in trial batches brings the benefit of real data back to the production chemist—shortening the path between idea and market launch.

    New polymer blends targeting high-performance sports gear, automotive parts, or even renewable energy hardware often require subtle tweaks—like placing functional groups midway along the alkyl chain instead of at the ends. The gains might not always show up as headline numbers but can change the value chain dramatically. Enhanced weatherability, better mechanical properties, and greater recyclability start with just such molecular fine-tuning. I’ve seen industry partners win contracts after adjusting formulations using mid-chain brominated building blocks, beating out established competitors who played it safe with off-the-shelf materials.

    Looking Ahead: Solutions for Sustainability and Performance

    The future of specialty chemistry leans toward responsible design and operations. Reliable intermediates—like 9-(Bromomethyl)Nonadecane—help the industry chart a smarter path by enabling targeted syntheses that avoid overuse of hazardous reagents and cut down on resource consumption. Lab teams and manufacturers alike adopt process intensification, continuous production, and better waste segregation to maximize safety and cost savings.

    Researchers working with alkyl bromides also look for catalytic or one-pot protocols that make their downstream processes more sustainable. Mid-chain brominated compounds lend themselves readily to such approaches because they cut out lengthy pre-functionalization and post-reaction cleanups. In my own projects, whenever I’ve used a compound that makes shortcuts possible, the time and resources saved free me up to tackle bigger challenges—whether that’s optimizing yield or scaling up for a product launch.

    Collaboration between labs and raw material suppliers, supported by transparent testing and reporting, keeps quality high and use consistent from lot to lot. With the right documentation and open lines of communication about specification changes, companies using 9-(Bromomethyl)Nonadecane keep their supply chains smooth. From my consulting experience, those who track quality data and share best practices face fewer production upsets and regulatory setbacks. It all comes back to using well-characterized ingredients in your critical steps.

    Conclusion: Rethinking the Role of Bromomethyl Compounds

    9-(Bromomethyl)Nonadecane carves out its own space in the specialty chemical landscape by offering a versatile, reliable, and efficient platform for advanced synthesis. Its combination of structural length and mid-chain reactivity fits both experimentalists searching for the next big leap and formulators who need to hit target specs again and again. With the industry’s eyes set on sustainability, quick turnaround, and reduced waste, compounds like this push the frontier forward. Many who work with it aren’t just following a trend—they’re shaping solutions for safer, more effective, and better-performing products across chemical, pharmaceutical, and materials science sectors.