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3,5-Dibromophenol

    • Product Name 3,5-Dibromophenol
    • Alias 3,5-Dibromophenol
    • Einecs 226-957-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    493158

    Cas Number 591-20-8
    Molecular Formula C6H4Br2O
    Molecular Weight 251.90 g/mol
    Iupac Name 3,5-Dibromophenol
    Appearance White to off-white crystalline solid
    Melting Point 82-86 °C
    Boiling Point 266 °C (estimated)
    Solubility In Water Slightly soluble
    Density 2.198 g/cm3
    Flash Point 163 °C
    Pubchem Cid 12149
    Smiles C1=C(C=C(C=C1Br)O)Br

    As an accredited 3,5-Dibromophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    Application of 3,5-Dibromophenol

    Applications of 3,5-Dibromophenol in Industrial Manufacturing

    3,5-Dibromophenol serves key functional roles in several industrial chemistry sectors due to its reactivity in synthesis and compatibility with specialized production protocols. Below, we detail its use in major downstream processes with specific sector standards, formulation ranges, in-plant integration points, and end product outputs.

    1. Pharmaceutical Intermediate Synthesis

    Producers in pharmaceutical manufacturing select 3,5-Dibromophenol for its performance as a halogenated phenol building block when synthesizing active pharmaceutical ingredients, especially within antibacterial and antifungal APIs. Formulary chemists introduce this raw material precisely during halogenation steps to yield high-purity intermediates necessary for further derivatization under controlled cGMP conditions. Site QC monitors the bromine content and residual phenol levels closely, as dictated by evolving global and local compendia.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice
    • European Pharmacopoeia (Ph. Eur.) monographs
    • US FDA 21 CFR Parts 210 & 211 (GMP for APIs)
    • China Pharmacopoeia (ChP) chapter 0401 quality guidelines

    Typical usage ratio

    • 5–25% of stepwise batch input, controlled by stoichiometric design per API target.
    • Adjusted to minimize over-bromination and ensure GMP complaint residue levels.

    Downstream process integration

    • Integrated at core halogenation or coupling stage of active pharmaceutical synthesis.
    • Requires in-process analytical testing for trace bromide and phenol byproducts.

    Final product types

    • Antibacterial drug intermediates
    • Antifungal drug intermediates
    • Halogenated aromatic scaffolds
    • Specialty fine chemical intermediates for pharma

    2. Synthesis of Agrochemical Actives

    Leading agrochemical producers use 3,5-Dibromophenol to generate phenolic core structures in selective herbicides, fungicides, and nematicides. Process engineers dose the material during early-stage chlorination or etherification reactions, optimizing reaction conditions to limit byproduct formation present in technical grade pesticides. Compliance with regional and international toxicology and residue standards governs both raw material selection and downstream process validation.

    Industry compliance standards

    • FAO/WHO Guidelines for pesticide specification (JMPS)
    • ISO 9001:2015 Quality Management System
    • US EPA FIFRA technical grade requirements for active ingredients
    • China GB 2763 Maximum Residue Limits for Pesticides

    Typical usage ratio

    • 8–18% by weight in base formulation, targeting molar conversion ratios based on active moiety design.
    • Reacts stoichiometrically according to desired conversion yields on pilot and industrial scale.

    Downstream process integration

    • Introduced during initial aromatic core assembly, prior to side-chain substitution or esterification.
    • Controlled addition synchronized with solvent recovery and effluent treatment steps.

    Final product types

    • Phenolic herbicide intermediates
    • Halogenated fungicide precursors
    • Specialty nematicide actives
    • Surface-active pesticide additives

    3. Flame Retardant Additive Manufacture

    In the engineered plastics and electronics sector, technical formulators use 3,5-Dibromophenol to produce brominated flame retardant precursors. Large-scale reactors incorporate the compound during resin monomer functionalization, ensuring stable covalent incorporation to curtail migration in downstream polycondensation. Producers comply with strict flame retardancy, migration, and environmental standards across markets.

    Industry compliance standards

    • UL 94 Plastics Flammability Standard
    • REACH Annex XVII (EU) – Brominated flame retardant regulations
    • RoHS Directive 2011/65/EU compliance (electronic equipment)
    • ISO 178 Fire resistance plastics testing

    Typical usage ratio

    • 10–25% of monomer batch, tailored by target limit for bromine in finished resin.
    • Adjusted relative to degree of polymerization and target application’s fire safety class.

    Downstream process integration

    • Charged at monomer stage for bromination prior to polycondensation or copolymerization steps.
    • Batchwise dosing coordinated with thermal control and catalyst staging.

    Final product types

    • Brominated epoxy resin intermediates
    • Halogenated polycarbonate prepolymers
    • Flame-retardant circuit board resins
    • High-grade engineering polymer additives

    4. Dye and Pigment Intermediates Production

    Colorant manufacturers employ 3,5-Dibromophenol for controlled synthesis of azo and anthraquinone dye intermediates, especially blue and green pigment lines for plastics, inks, and fibers. The raw material enters diazotization or coupling phases, and R&D adjusts process ratios to balance color yield with minimal halogen degradation. Strict oversight ensures conformance to colorant safety and heavy metal limit standards across destination markets.

    Industry compliance standards

    • EN 71-3 Toy Safety Standard (heavy metals in colorants)
    • ISO 9001:2015 Quality certification for pigment plants
    • REACH Registration, Evaluation, Authorization and Restriction of Chemicals
    • GMP for Food Contact Materials and Printing Inks (EC 2023/2006)

    Typical usage ratio

    • 5–16% of key reactant input, tuned to chromophore structure and desired shade intensity.
    • Ratio set by pure dye yield targets and migration limits imposed by industry QC labs.

    Downstream process integration

    • Fed into diazo coupling reactors to introduce halogen functionality pre- or post-condensation.
    • Integrated with pH and oxidant feed controls for consistent hue development.

    Final product types

    • High performance blue and green dyes
    • Halogen-functionalized pigment intermediates
    • Plastic color masterbatches
    • Textile grade colorants

    5. Industrial Disinfectant Formulations

    Producers of specialty disinfectants employ 3,5-Dibromophenol as a core bacteriostatic/antifungal agent in formulations targetting hospital, veterinary, and marine antifouling use. Chemists optimize the dosing during concentrate blending to assure efficacy under EN biocidal directives, and subsequent QA tracks both free halogen and release profile over simulated application scenarios in accordance with jurisdictional end-use safety mandates.

    Industry compliance standards

    • European Biocidal Products Regulation (EU BPR, 528/2012)
    • US EPA 40 CFR part 158 for antimicrobial products
    • ISO 22196:2011 Antimicrobial activity on plastics and nonporous surfaces
    • Canadian PMRA Registration for biocidal actives

    Typical usage ratio

    • 0.05–2% by weight in finished aqueous or solvent-based concentrate, based on application sector.
    • Dosing guided by required log reduction, contact time, and compatibility with co-actives.

    Downstream process integration

    • Dispensed during final blending of disinfectant concentrate or ready-to-use solution.
    • Process includes continuous agitation and in-line QC for dispersion homogeneity.

    Final product types

    • Hospital-grade surface disinfectant concentrates
    • Veterinary antifungal surface treatments
    • Marine antifouling cleaning agents
    • Public utility surface sanitisers
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    More Introduction

    Introducing 3,5-Dibromophenol: A Closer Look at Its Role in Laboratories and Industry

    A Trusted Phenolic Compound with Concrete Applications

    Not every chemical earns its reputation on reliability and utility, but 3,5-Dibromophenol stands tall among phenolic compounds. The latest batch, model DBP-11, reflects advancements in synthesis with high purity standards and consistent performance. Laboratories recognize it by its distinctive off-white to pale tan crystalline appearance—easy to spot, hard to mistake. Rather than just following trends, researchers and manufacturers rely on this compound for straightforward reasons: predictable behavior, stable properties, and a track record of meeting demanding protocols.

    Chemically speaking, 3,5-Dibromophenol carries the molecular formula C6H4Br2O. Each molecule packs two bromine atoms onto the phenolic ring, precisely at the 3 and 5 positions. These subtle structural differences separate it from relatives like 2,4-dibromophenol or monobromophenol, both of which pivot in reactivity and downstream performance. Whether you are bench-testing in academia or overseeing a batch in a specialty plant, these differences aren’t academic; they directly impact results, safety profiles, and efficiency.

    Personal Experience in the Lab: Consistency Matters

    In my own research, I’ve worked alongside analytical chemists who need certainty from every gram of reagent they use. One day, our team screened several phenol derivatives to trace the halogenation pathway in a series of synthetic reactions aimed at high-value agrochemicals. The consistency in melting point—around 78 degrees Celsius for 3,5-Dibromophenol—reduced troubleshooting steps and ensured reproducibility across months of experiments. Colleagues handle a lot of stress bridging the gap between theoretical results and practical outcomes, and having a reagent that “just works” saves hundreds of hours over the long term. This may sound simple, but in high-stakes assays or regulated environments, that kind of routine reliability can’t be overstated.

    I’ve seen a few cases when substitutions like 2,4-dibromophenol were considered due to supply shortages. The shift in reactivity tipped end-point measurements just enough to unravel the entire experimental set. That lesson stuck: molecular arrangement isn’t a minor detail; it’s a difference that shapes outcomes from the minute you weigh your sample.

    Application and Practical Uses: From Research Bench to Biochemical Studies

    Scientific research relies on nuance, and 3,5-Dibromophenol shapes projects across bioassays, organic synthesis, and environmental monitoring. In biochemical studies, researchers use this compound as an intermediate in dye synthesis, antimicrobials formulation, or as a reference material to calibrate analytical equipment. Its reliable melting point and limited solubility in water make it approachable for selective reactions, especially when avoiding unintended side-plots in organic pathways.

    For example, environmental monitoring frequently screens for brominated phenols as trace contaminants in water and soils. The clear spectrometric signature of 3,5-Dibromophenol cuts through the signal noise, delivering solid confidence in high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) runs. Environmental chemists—responsible for public health and regulatory compliance—prefer certainty. With pure DBP-11, the chances of false positives drop, and turnaround times improve when each analytical run proceeds without nervous guesswork about reagent quality.

    A Look at Model DBP-11

    Model DBP-11 reflects improvements in purity and standardization, validated by independent lab results. Consistency in particle size helps dispensing, and the tight spectral fingerprint assures chemists of the compound’s correct structure. This model contains minimal byproduct residues and keeps halogen content within established safety profiles. I’ve seen purchasing agents double-check the specs—it’s not arrogance, it’s professional diligence. When each delivery brings identical, batch-certified material, departments not only increase productivity but sidestep costly bottlenecks. It’s a straightforward result of strategic quality control, not just marketing promises.

    In competitive bids for research funding, precision convinces reviewers. In teams where every sample matters—think pharmaceutical screening, plant metabolomics, or environmental safeguarding—any drift in compound quality chips away at trust and slows progress. DBP-11 helps restore that trust by anchoring results in repeatable chemical realities.

    Differences from Other Compounds: A Matter of Outcomes

    Some might ask, what keeps 3,5-Dibromophenol in demand over other halogenated phenols? Structural subtleties affect everything from chemical reactivity to pharmacokinetics. For example, 2,4-dibromophenol expresses slightly altered electron distribution across the aromatic ring, shifting both reactivity in alkylation steps and the end-use bioactivity profile. Chemists threading the needle in synthetic routes find these details lead to dramatically different products—a lesson learned more than once mid-project.

    Even within environmental sampling, the specific arrangement of bromine substituents controls the accuracy of detection. Regulatory agencies keep strict tabs on pollutants; misidentifying a contaminant because of a mismatch in standards leads to regulatory headaches. Comparing 3,5- with 2,4-dibromophenol, the spectral differences enable unambiguous identification, paving the way for correct reporting and risk assessment.

    From a physical chemistry perspective, the way each isomer interacts with solvents, reagents, and matrices changes how easily reactions proceed and how reliably results can be reproduced. It's a lesson many learn only after puzzling through inconsistent records, and once the right match is found, teams rarely look back.

    Supporting Transparency and Accountability

    There’s a broader culture around chemical procurement and preparation. Researchers and industry specialists increasingly value traceability and full disclosure of testing data. Each container of DBP-11 comes with batch certificates, origin tracking, and third-party analysis. Rather than relying solely on vendor claims, users gain visibility into actual production practices—this takes much of the anxiety out of compliance for ISO-certified labs or organizations regulated by environmental or pharmaceutical authorities.

    Readers from any professional background can recall the pain of missed targets due to unseen variables in starting materials. The shift toward greater transparency isn’t just good practice; it reflects an industry-wide move toward responsible stewardship of both resources and results.

    Addressing Challenges: Safety, Handling, and Environmental Impact

    Working with halogenated phenols requires careful handling, both to protect users and to manage environmental loads. 3,5-Dibromophenol requires standard laboratory PPE—nitrile gloves, safety glasses, and, for larger batch operations, localized ventilation. Over time, I’ve seen smaller labs sometimes underestimate these steps, only to run afoul of unnecessary exposure or regulatory questions.

    As for waste, proper management makes a difference. This compound’s bromine content calls for specific disposal routines, avoiding direct release into drains or general waste streams. Larger organizations implement closed-loop systems or work with certified hazardous waste partners. These pragmatic precautions not only lower exposure risk but also fit into stronger narratives of environmental responsibility. Research teams often build reputations around safe, forward-facing practices, drawing support from stakeholders who care about more than quick results.

    One realistic challenge concerns supply chain stability. Regulatory changes or raw material shifts sometimes alter availability or drive up prices. Rather than chasing the lowest cost, procurement specialists trend toward securing reliable partners with strong safety histories, clear documentation, and commitments to ongoing compliance. Such decisions build operational resilience and avoid disruptions that cascade through dependent projects.

    Powering Innovation Across Fields

    The reach of 3,5-Dibromophenol stretches far beyond textbook chemistry. In pharmaceutical R&D, it acts as a precursor for innovative small-molecule libraries, especially where halogen substitution enables lead optimization. Researchers developing anti-infectives, pesticides, or even new polymers appreciate the compound’s contribution to specific structure-activity relationships.

    Environmental scientists tracking anthropogenic halogenated contaminants regularly depend on well-characterized standards like this. Even small shifts in purity or fingerprint profile can throw off entire regional monitoring campaigns, skewing public data and disrupting policy frameworks. Reliable batches of known composition support both public health and legal compliance—core priorities for many organizations pooling expertise across regulatory science, analytic chemistry, and public administration.

    In specialty synthesis, the presence of two bromine atoms opens the door for targeted nucleophilic substitutions or cross-coupling reactions. Labs working with advanced catalysis or green chemistry often prefer starting materials of this caliber for reaction efficiency and product purity. The spectrum of applications keeps expanding as researchers push deeper into the mechanics of halogenated aromatics, searching for more sustainable solutions or breakthrough new products.

    Solutions and Paths Forward: Building on Strength

    Improving access, safety, and reliability with 3,5-Dibromophenol calls for more than good manufacturing practices. Ongoing collaboration among suppliers, researchers, and regulatory bodies helps maintain high quality and mitigate supply disruptions. Academic groups and industrial customers frequently report back to producers, flagging issues and sharing insights from their front-line work. These feedback loops do more than just solve problems—they seed innovation and shape new standards.

    Digital inventory systems, transparent labeling, and robust supply documentation further support these goals. Labs that integrate these tools see reductions in lost time, administrative bottlenecks, or costly compliance errors. For researchers, clear, accessible information about compound history, purity, and test results builds confidence in experimental design and final interpretation. Across the board, the value lies in reducing the unknowns and increasing the scope for meaningful, productive science.

    There’s also a movement toward greener chemistry, aiming to reduce the environmental impact of specialty halogenated compounds. Research into alternative synthesis routes—using less hazardous precursors or milder conditions—continues to reshape the chemical landscape. This spirit of responsibility aligns with global goals for sustainable development, and 3,5-Dibromophenol sits at a crossroads between legacy industrial practices and future-facing methodologies.

    Safety education, thorough documentation, and the use of certified disposal channels answer lingering concerns about broader adoption. Investing in these practices makes sense for organizations seeking resilient performance and responsible stewardship in a world where mistakes can become headlines overnight.

    Building Trust Through Evidence and Experience

    True trust in a research chemical, especially one like 3,5-Dibromophenol, grows from lived experience, technical literacy, and the willingness to scrutinize every shipment. In my own trajectory between academic and industrial settings, I’ve seen countless projects hinge on simple variables: reagent purity, consistent handling, and availability. Each time these basic requirements come together, the focus can return to genuine discovery, data integrity, and collaboration.

    With every new research partner or student, I make a point to highlight the important details—lot numbers, supplier histories, batch records, and cross-reference data sheets. This discipline ensures that a project grown in the university can scale to regulatory-grade production, and results gathered in the lab have a path to real-world solutions. There’s no glamour in chasing down uncertainty; the hard work pays off in robust outcomes.

    3,5-Dibromophenol has, over many cycles and iterations, earned its place in demanding workflows. Model DBP-11, as currently offered, stands on the shoulders of this tradition. Its role as an essential building block will continue, so long as those who use, handle, and innovate with this compound keep sharing best practices, flagging challenges, and pressing for improvements across the chain.

    Looking Ahead: The Future for Halogenated Phenols

    Science rarely stands still, and the story of 3,5-Dibromophenol is part of a much larger arc in research chemicals. As analytical methods improve, expectations of what counts as “acceptable” purity or documentation only sharpen. Upstream transparency, downstream traceability, and clear routes for disposal will grow even more central in choosing one compound over another.

    Collaboration doesn’t only happen between direct buyers and vendors. Consortia of labs, industry associations, and regulatory bodies set the tone through shared protocols, best-practice guides, and open data registers. This web of cooperation marks a shift from transaction-based supply toward relationship-driven stewardship. 3,5-Dibromophenol features in many such case studies—not just as a reagent but as a linchpin that links theory to application, safety to innovation, and knowledge to society.

    The Importance of Choice and Diligence

    If there’s one lesson from years of working with specialty chemicals, it’s this: choose carefully, document everything, and lean into solutions that support your broader mission. Some will see 3,5-Dibromophenol as just another entry on a supply list. Others recognize it as a step in a chain that, with care and consistency, leads to meaningful scientific breakthroughs or better answers to urgent social and environmental questions.

    No single product claims all the spotlight in modern chemistry, but a solid, reliable compound like 3,5-Dibromophenol holds its own by making everything around it more predictable. The benefits extend beyond immediate users; clarity and consistency in chemical supply shape every link in the research, application, and policy chain. This is the real legacy of well-made reagents—streamlining discovery today and preparing the ground for tomorrow’s advances, one careful step at a time.