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1-Bromo-2-Chlorotetrafluoroethane

    • Product Name 1-Bromo-2-Chlorotetrafluoroethane
    • Alias Halon 1211
    • Einecs 216-898-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    727184

    Cas Number 354-56-3
    Molecular Formula C2BrClF4
    Molar Mass 233.38 g/mol
    Appearance Colorless liquid
    Boiling Point 47 °C
    Melting Point -112 °C
    Density 1.82 g/cm³ (at 25 °C)
    Refractive Index 1.358 (at 20 °C)
    Solubility In Water Insoluble
    Vapor Pressure 307 mmHg (at 25 °C)

    As an accredited 1-Bromo-2-Chlorotetrafluoroethane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 500 mL amber glass bottle, tightly sealed, labeled "1-Bromo-2-Chlorotetrafluoroethane," with safety, hazard, and handling instructions.
    Shipping 1-Bromo-2-Chlorotetrafluoroethane is shipped as a hazardous material, typically in secure, sealed chemical containers or cylinders. Packaging must comply with international regulations due to its potentially harmful effects. Appropriate labeling and documentation indicating its halogenated nature and handling precautions are required. Only authorized carriers should transport this chemical under controlled conditions.
    Storage **1-Bromo-2-chlorotetrafluoroethane** should be stored in a tightly sealed container within a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. It should be kept separate from incompatible substances such as strong oxidizers. Proper labeling and spill containment measures are essential, and storage areas must be equipped to handle potential leaks or accidental releases.
    Application of 1-Bromo-2-Chlorotetrafluoroethane

    Applications of 1-Bromo-2-Chlorotetrafluoroethane in Industrial Manufacturing

    As a direct producer of 1-Bromo-2-Chlorotetrafluoroethane, we supply batches to clients operating within environmentally controlled and regulated technical fields. This specialty halocarbon serves as a performance fluorinating agent, intermediate, and system component in several discrete high-value downstream industries. Below we detail core industrial applications, process roles, regulatory environment, typical formulation information, and the ultimate products manufactured using this chemical.

    1. Refrigeration System Blend Component

    System designers in high-performance cooling routinely specify this bromochloro-fluorocarbon as a blend part in low-temperature refrigerant charges. It delivers high density, excellent compatibility with fluorinated base lubricants, and fine-tuning of vapor pressure curves for cascade and ultra-low refrigeration systems. Our technical support ensures blend ratios align with compressor requirements, lubricant solubility, and local environmental phase-down schedules.

    Industry compliance standards

    • ASHRAE Standard 34 (Safety Classification of Refrigerants)
    • EU F-Gas Regulation (517/2014)
    • EN 378:2016 (Refrigerating Systems and Heat Pumps Safety)
    • REACH Registration (if supplied to EU)

    Typical usage ratio

    • Used at 3%–8% by mass in non-flammable blended refrigerant formulations. Adjust blend based on charge size, evaporator design, and charge retention.

    Downstream process integration

    • Charged directly with other refrigerants under vacuum in the final system assembly phase. Batch QC adjusts charge ratio to optimize thermodynamic properties per system design data.

    Final product types

    • Ultra-low temperature medical freezers
    • Environmental test chambers
    • Precision laboratory refrigeration
    • Industrial cascade cooling systems

    2. Fluorinated Pharmaceuticals Intermediate

    Major pharmaceutical manufacturers use this material as a building block in multistep syntheses of specific functionalized active compounds. Its unique halogenation pattern facilitates clean stepwise transformations for APIs involving regulated fluorine and bromine moieties. Purity levels, trace metal controls, and documentation remain critical throughout the chain of custody, especially under GMP regimes.

    Industry compliance standards

    • ICH Q7 GMP Guide for Active Pharmaceutical Ingredients
    • USP General Chapters — Residual Solvents Guidance
    • 21 CFR Part 211 (US FDA cGMP for APIs)
    • Ph. Eur. Monographs (where downstream API is registered in Europe)

    Typical usage ratio

    • Applied at the stoichiometric equivalent to the required halogen source, generally 10–30% molar ratio per target synthetic sequence. Exact amount is tightly controlled by validated process steps.

    Downstream process integration

    • Feeds as a halogenic starting material during the second or third stage of a multi-step organic synthesis, often under anhydrous and inert conditions. All handling occurs in dedicated GMP reactors with continuous in-process controls.

    Final product types

    • Fluorinated active pharmaceutical ingredients (APIs)
    • Specialty halogenated intermediates
    • Radiopaque contrast agents
    • Candidate fluorine-containing drugs undergoing clinical development

    3. Chemical Vapor Deposition Gas for Electronics

    Key players in semiconductor fabrication rely on this specialty gas as a selective etchant and fluorine donor in chemical vapor deposition (CVD) processes. The predictable decomposition mechanism and compatibility with etch chamber hardware allow precise patterning of silicon wafers, oxide films, and fine metallic structures. End-users demand tight batch-to-batch consistency, impurity profile records, and advanced packaging to maintain cleanroom standards.

    Industry compliance standards

    • SEMI S2 (Semiconductor Equipment and Chemical Safety)
    • ISO 14644 (Cleanrooms and Associated Controlled Environments)
    • JIS K 0554 (Packaging for Industrial Gases in Japan)
    • EPA Toxic Substances Control Act (for US-imported gases)

    Typical usage ratio

    • Supplied as pure gas or precise 10–25% mixtures by volume with carrier gases such as Argon or Nitrogen, depending on etch selectivity and film type. Gas flow rates are metered by mass flow controllers on the deposition line.

    Downstream process integration

    • Introduced into plasma CVD or dry etch chambers at critical patterning steps. Automated gas panels deliver and exhaust the material via high-purity lines, monitored for trace moisture and metals prior to wafer exposure.

    Final product types

    • Semiconductor integrated circuits (ICs)
    • Thin film transistor LCDs (TFT-LCDs)
    • Photomask blanks and patterned substrates
    • High-density interconnect printed circuit boards (HDI PCBs)

    4. Specialty Solvent for Fluoropolymer Processing

    Producers of advanced fluoropolymers and engineered plastics select this halogenated compound as a specialty solvent for polymerization, reactive cleaning, and pre-polymer treatments. Its chemical structure prevents unwanted side reactions and contributes unique solvency properties for specific resin systems, including certain PTFE derivatives and fluoroelastomers. Batch QA data and solvent recycle potential play key roles in supply chain decisions.

    Industry compliance standards

    • ISO 9001:2015 (Quality Management Systems for Manufacturers)
    • ASTM D740 (Solvent Purity for Industrial Use)
    • OSHA 29 CFR 1910.1200 (Chemical Hazard Communication, US)
    • RoHS 2011/65/EU (Restriction of Hazardous Substances, EU plastics)

    Typical usage ratio

    • Incorporated at 5–20% by weight during pre-polymerization, with precise adjustment based on monomer feedstock, molecular weight target, and post-reaction handling.

    Downstream process integration

    • Added to polymerization vessels prior to monomer introduction or during specialty in-line cleaning of process reactors. Solvent recovered via distillation may be reused contingent on QA clearance.

    Final product types

    • Fluoroelastomer compound masterbatches
    • High-purity PTFE granules
    • High-performance fluoropolymer films
    • Engineered O-rings and seals for chemical service

    5. Military and Aerospace Extinguishing Formulation Intermediate

    Manufacturers of advanced fire suppression systems for military and aerospace applications specify this chemical as a performance-modifying intermediate in proprietary halon replacement blends. Its rapid response thermal degradation and gas evolution characteristics supplement system activation under high-pressure and rapid-deployment situations. Documentation is maintained for full chain of custody and conformance with defense procurement standards.

    Industry compliance standards

    • NFPA 2001 (Standard on Clean Agent Fire Extinguishing Systems)
    • UL 2127 (Standard for Inert Gas Clean Agent Extinguishing Systems)
    • US MIL-STD-810 (Environmental Engineering Considerations and Laboratory Tests, military equipment)
    • Montreal Protocol Compliance for Halocarbons

    Typical usage ratio

    • Use rate in concentrated agent mixtures typically 2–6% by mass. Formulation ratio tailored to required activation profile, protected volume, and environmental release limits.

    Downstream process integration

    • Blended in hermetically sealed agent reservoirs with other clean agents and additives. High-shear mixing under nitrogen blanketing maintains blend homogeneity until transfer to final system canisters.

    Final product types

    • Aerospace fire suppression modules
    • Military ground vehicle extinguishing systems
    • Aviation engine compartment suppression devices
    • Portable military-grade agent canisters
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    Certification & Compliance
    More Introduction

    Introducing 1-Bromo-2-Chlorotetrafluoroethane: A Deeper Look at a Niche Chemical

    A Closer Look At 1-Bromo-2-Chlorotetrafluoroethane

    1-Bromo-2-Chlorotetrafluoroethane stands out among halogenated ethane derivatives, not just for its intricate name, but for the specific balance of properties it offers to chemists and industries. Many years spent in specialized chemical environments taught me that the finer points of a compound’s structure—the number of fluorine atoms, the interplay of bromine and chlorine—determine everything about how a chemical performs and how safe it can be used. This substance, with its precise ratio of halogens, feels like the result of many rounds of scientific trial and error, seeking a balance between reactivity, stability, and usability.

    This model of halogenated ethane, featuring a single bromine atom, a chlorine atom, and four tightly bound fluorine atoms, showcases a unique blend that doesn’t appear in every lab catalog. The arrangement offers not just chemical curiosity, but a practical basis for targeted applications. Most users approach 1-Bromo-2-Chlorotetrafluoroethane with a defined goal—often in sectors like electronics, specialty refrigeration, advanced material synthesis, or specific cleaning processes. These uses usually come from its chemical characteristics: moderate boiling point, reliable inertness in certain conditions, and capabilities stemming directly from halogen atom placement.

    Why This Blend Matters: Unpacking Genuine Chemistry Value

    In a world of thousands of industrial chemicals, the structure of 1-Bromo-2-Chlorotetrafluoroethane provides it with a special identity. Four fluorine atoms give it a backbone of stability against many aggressive chemical environments. Adding chlorine and bromine changes its performance—these atoms can enhance reactivity in controlled conditions without sacrificing its resistance to degradation under normal usage. My direct experience handling halogenated organics suggests that bromine, heavier and more reactive than fluorine or chlorine, often turns these compounds into potent agents for targeted synthesis, or, on the flip side, makes them easier to neutralize or break down safely.

    Colleagues in specialty fabrication and advanced electronics often select this molecule when alternatives—whether pure fluorocarbons or more common brominated ethanes—fall short. It comes down to a mix of safety, performance, and manageable cost. Products bearing all four fluorine atoms push stability to high levels but can lack the desired reactivity for certain syntheses or circuit cleaning procedures. Bring bromine and chlorine into the picture, and you see changes in how the molecule behaves: adjusted volatility, improved solubility for some organics, or better interaction with metals or polymers.

    Specifications That Carry Real-World Impact

    The particulars of 1-Bromo-2-Chlorotetrafluoroethane, such as purity, phase at room temperature, and volatility, drive the product’s suitability for its roles. As someone who has experimented with various grades of halogenated chemicals, I have found that high-purity forms give users the consistency they seek for research, testing, or pilot production. At room temperature, this compound generally appears as a volatile liquid, easy to handle in closed systems and less likely to linger as a contaminant. In most industrial environments, these traits mean fewer process interruptions and cleaner final outcomes.

    Another aspect that sets this molecule apart: its moderate boiling point compared to common pure fluorocarbons or chlorinated ethanes. This allows for evaporation-driven applications—like gentle cleaning or drying—without excessive losses to the air or risky pressurization. The molecule’s density, refractive index, and solubility profiles fit specific needs, which emerge in tasks like circuit cleaning, dielectric fluid formulation, or certain medical device manufacturing workflows. Each parameter plays into the hands-on choices engineers and lab techs make every day.

    Differentiation from Other Halogenated Ethanates

    Not every halogenated ethane tells the same story. Some, like dichlorotetrafluoroethanes, remain stable but lack reactivity for modern manufacturing. Others, such as 1,1,2-Trichloro-1,2,2-trifluoroethane, might break down more readily or pose greater environmental concerns. In contrast, 1-Bromo-2-Chlorotetrafluoroethane often strikes the middle ground—a compound that provides good chemical stability without some of the regulatory baggage of legacy solvents and without the hazardous breakdown products sometimes seen with heavily chlorinated or brominated cousins.

    People who have worked with a shelf full of halogenated ethanes will notice subtle differences in odor, evaporation, or even color. The presence of bromine deepens the safety mark, demanding respect from handlers and extra attention to storage and use. In my experience, regular chlorofluorocarbons can handle gentle cleaning and cooling tasks but often come with ozone-depletion or persistence risks. Moving partial bromination and chlorination into the molecule alters its breakdown pathways, sometimes offering faster decomposition under controlled destruction procedures—relevant not just for industry, but for regulators and environmental scientists.

    The Usage Landscape: Real-World Cases and Tastes

    I have seen 1-Bromo-2-Chlorotetrafluoroethane used where precision cleaning requirements go beyond the reach of many other solvents. In repair depots for aerospace electronics, for example, too many solvents leave insulating residues or provoke corrosion. This molecule’s balance of volatility and chemical inertness tends to produce fewer problems and more reliable results, especially on sensitive alloys or complex electronic assemblies. That reassurance means less rework, lower scrap rates, and smoother logistics.

    Certain refrigeration and specialty cooling scenarios have also built around this compound. Its boiling point lands it in a "just right" zone—not so high it resists evaporation, not so low it rushes away in open systems. In large-scale systems where chlorofluorocarbons have fallen out of favor due to regulatory pressure, variations like this offer a potential alternative that performs without the same set of regulatory headaches. People on the front lines of equipment maintenance appreciate that—a coolant which doesn’t attack seals, degrade in pumps, or require total system replacement every five years.

    Beyond Industrial: Research Goals and Emerging Trends

    While industrial users keep this molecule in demand, researchers keep finding new value as well. Recent work in fluorine chemistry highlights the potential of these compounds as intermediates in pharmaceuticals or specialty agrochemicals. The balance of reactivity to stability, always tricky in halogenated moleules, has pushed 1-Bromo-2-Chlorotetrafluoroethane into focus for catalytic studies, especially in reactions that call for selective activation. Having worked in chemical research environments, I understand the headaches caused by unstable or impure solvents; a stable, well-characterized liquid like this makes experimental results more meaningful and reproducible.

    Emerging sectors, including advanced coatings and new battery technologies, explore these types of molecules for their electrochemical stability and low-flammability profile. In these research contexts, lab managers measure every drop, assess every emission, and track every disposal cost, so differences in composition resonate at both the test-bench and budget sheet. Feedback from these innovators points to the importance of sourcing, traceability, and clear environmental fate—and this compound, compared with lesser-known or less characterized alternatives, gives more predictable profiles.

    Environmental and Safety Realities

    Every chemical with a halogen in the mix, especially those with bromine, earns close inspection from both regulators and those of us who use them. There’s a plain truth in the chemical industry: safety, compliance, and responsible use can’t be separated from innovation or cost control. 1-Bromo-2-Chlorotetrafluoroethane brings challenges alongside its benefits. In labs where I have worked, strict storage and ventilation standards go hand-in-hand with training and spill-response protocols. It’s never just about the Material Safety Data Sheet; experience counts at every turn. Teams who take shortcuts risk exposure, equipment damage, or, less often, regulatory reprimands that slow everything down.

    Compared to legacy compounds famous for ozone layer destruction, or more modern replacements that trade toxicity for persistence, 1-Bromo-2-Chlorotetrafluoroethane reaches a more balanced spot—though not a risk-free one. Debate continues around environmental fate and breakdown products. Limiting releases, improving recovery and reclamation, and investing in closed-system technology remain common-sense steps. I have found that most places using this compound already emphasize leak prevention and rigorous waste tracking; the most responsible users invest in on-site destruction or treatment, sometimes upgrading their processes just to work with safer or more manageable intermediates.

    Current Regulatory View and What It Means

    The regulatory tide for halogenated methanes and ethanes has shifted repeatedly over the last few decades, so clarity matters. International agreements, such as the Montreal Protocol, inspired companies and labs to rethink solvent choices, refrigerants, and cleaning agents. While this specific compound doesn’t always land in the strictest regulatory baskets, regions and industries manage their risk differently. Whether in the US, the EU, or parts of Asia, the paperwork and permitted applications don’t always overlap. I have faced compliance reviews that turn on one molecule’s environmental persistence compared to a near-identical cousin. Working with this compound often means documentation, emissions reporting, and ongoing dialogue with local authorities.

    For procurement and compliance teams, those rules matter as much as boiling points or cleaning performance. Having all the data on composition, traceability, and safe usage practices makes life easier—not just for paperwork, but for cross-department cooperation. It’s these real-world factors, not just theoretical strengths, that separate success from frustration, especially in industries moving from older solvent protocols to newer, better regulated alternatives. From my perspective, clear internal policies and ongoing employee training become non-negotiable, shaping not only compliance but the overall safety culture.

    Solutions and Responsible Use: Moving the Needle

    Problems with halogenated ethanes rarely disappear overnight. My years adjacent to environmental safety teams convinced me that technology leads, but culture changes seal the deal. Users can make a difference with simple process improvements: shifting to closed-loop cleaning systems, capturing evaporated product, or partnering with certified chemical disposal firms. These actions might sound mundane, but their collective impact changes both environmental and workplace outlooks. Companies with a reputation for clean records and low emissions set themselves up for easier regulatory transitions and lower insurance rates.

    Another meaningful solution comes from information sharing. Whether through industry groups or regular cross-company roundtables, the best insights often come from unexpected sources: a technician in one plant figures out a filtration trick, an engineer elsewhere spots a subtle equipment vulnerability. Trust forms where open discussion replaces defensive corporate habits. My experience echoes the evidence—investing in communication not only supports compliance but breeds innovation in product applications, storage, and safe handling.

    From another perspective, alternative chemistries continue to improve all the time. Some companies already reduce their reliance on chlorinated or brominated ethanes by trialing green solvents, exploring non-fluorinated options, or shifting to entirely different methods (like laser or supercritical CO2 cleaning). The transition doesn’t always make sense for every workflow, but industry-wide R&D narrows the gap on performance, cost, and safety every year. For those who depend on halogenated ethane derivatives right now, watching this landscape and actively testing new products as pilot projects can create a smoother pathway as regulatory and economic factors evolve.

    Putting It Into Daily Practice

    Most people who deal with specialty chemicals don’t work in policy silos, or just shuffle paperwork. They handle products in real time, answer safety questions, interface with engineers, and field questions from downstream users. I have watched the best teams share knowledge freely, anticipating problems before they escalate. That culture hand-in-hand with the technical aspects of using products like 1-Bromo-2-Chlorotetrafluoroethane keeps operations running smoothly and helps carry the broader industry forward.

    To get the most out of using this molecule, companies and technicians focus on three areas: precision (making sure the right grade and batch get to the right process), safety (maintaining rigorous standards and refreshing training regularly), and efficiency (using just enough, recapturing what they can, and spending wisely on disposal). Cutting corners in any one lets performance or safety slip. I have learned that trust between management and technical staff often turns on how they handle potent chemical products like this—transparent processes reduce risk, increase reliability, and support better business outcomes.

    Users who understand what makes 1-Bromo-2-Chlorotetrafluoroethane different from other similar compounds gain better control and more flexibility. That knowledge grows from both shared experience and from study, whether through technical training programs, internal communications, or even simple weekly safety meetings. The real insights, in my view, don’t come from charts or regulatory documents alone—they come from people comparing notes, sharing troubleshooting moments, and passing along stories of what worked or what didn’t on the plant floor.

    Looking Forward With 1-Bromo-2-Chlorotetrafluoroethane

    Nothing in specialty chemicals stands still for long. Regulatory pressures, market shifts, and new technology all play their part in shaping which compounds will stick around, which will fall out of favor, and which will transform into something else entirely. I’ve found that companies willing to keep their eyes open—to watch the intersection of chemistry, regulation, and operations—tend to survive and thrive. For those who know 1-Bromo-2-Chlorotetrafluoroethane well, the future calls for ongoing adaptation. Sometimes this means swapping it for greener options; other times, it involves finding smarter ways to use it, store it, and dispose of it.

    The heart of responsible use always stays the same: understand both the strengths and the limits of the product. Build a workplace culture of careful handling, knowledge, and transparency. Stay connected to both the regulatory environment and the evolving science. For technical teams, managers, and researchers looking to balance great performance with real-world responsibility, 1-Bromo-2-Chlorotetrafluoroethane still has much to offer—if used with open eyes and steady hands.