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Product Name: Gamma-Aminobutyric Acid
Synonyms: 4-Aminobutyric Acid, GABA
Chemical Formula: C4H9NO2
CAS Number: 56-12-2
Recommended Use: Laboratory chemicals, research and development, as a biochemical
Restrictions on Use: Non-food, non-drug, not for household or consumer purposes
Supplier Details: Manufacturer or supplier information including address and emergency phone number as listed on the procurement paperwork or chemical catalog
Classification: Not classified as hazardous under GHS regulations
GHS Label Elements: No pictogram or signal word required
Statements of Hazard: May cause mild irritation to eyes, skin, or respiratory tract on contact or inhalation
Potential Health Effects: Possible mild irritant by ingestion, contact, or inhalation; not an acute toxin
Environmental Hazards: No specific hazard to aquatic life identified from published data
Other Hazards: Dust may form explosive mixtures with air in rare circumstances within industrial settings
Chemical Identity: Gamma-Aminobutyric Acid
Common Name: GABA
Concentration: 98-100% (pure substance)
Impurities: Trace manufacturing residuals below 1% as specified by supplier batch test
Additives: None indicated for analytical grade product
Eye Contact: Rinse eyes thoroughly with plenty of clean water for several minutes, holding eyelids open, remove contact lenses if present, seek medical advice if irritation develops
Skin Contact: Wash contacted area with soap and water, remove contaminated clothing, consult a physician if redness or discomfort persists
Inhalation: Move affected person to fresh air immediately, encourage deep breathing, obtain medical attention if symptoms like coughing or wheezing develop
Ingestion: Rinse mouth with water, drink water to dilute, do not induce vomiting, seek medical attention if unwell
Most Important Symptoms: Mild irritation to exposed tissues, minimal systemic toxicity
Immediate Medical Attention: Only sought if symptoms persist or an allergic reaction appears
Suitable Extinguishing Media: Use water spray, foam, carbon dioxide, or dry chemical
Unsuitable Extinguishing Media: Avoid high-pressure water jets which may spread dust
Specific Hazards: Product may burn at high temperature forming nitrogen oxides, carbon monoxide, and carbon dioxide
Protective Equipment: Firefighters should wear standard protective clothing, self-contained breathing apparatus
Hazardous Combustion Products: Nitrogen oxides, carbon monoxide, carbon dioxide, possible traces of ammonia
Special Procedures: Cool nearby containers exposed to fire with water, avoid inhaling combustion fumes
Personal Precautions: Avoid generating dust, ventilate area, use personal protective equipment as specified
Environmental Precautions: Prevent large spills from entering drains or waterways
Methods for Clean-Up: Sweep up material using non-sparking tools, avoid raising dust, transfer to a labeled waste container for proper disposal
Decontamination: Rinse area with a small amount of water after bulk material removal
Disposal of Collected Material: Place waste into approved waste containers, follow local disposal regulations
Handling: Keep containers tightly closed, use in well-ventilated areas, avoid inhaling dust or vapors, wear recommended personal protective equipment for eyes, skin, and respiratory system
Hygiene Measures: Wash hands and face after handling, do not eat, drink or smoke in working areas
Storage: Store in cool, dry, well-ventilated area, keep away from strong oxidizers or acids, protect from direct sunlight and moisture
Incompatible Materials: Avoid contact with strong oxidizing agents, reducing agents, and strong acids
Other Storage Conditions: Store in original labeled containers, keep storage area clean and organized
Occupational Exposure Limits: Not established for GABA, observe limits for nuisance dust set by OSHA/ACGIH (<10 mg/m³ for inhalable, <3 mg/m³ for respirable)
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize airborne particulates
Personal Protective Equipment: Chemical safety glasses, lab coat or coveralls, chemical-resistant gloves, dust mask or particle respirator if dust generation is expected
Environmental Controls: Avoid release into environment, clean up any spills immediately, dispose of contaminated material properly
Appearance: White to off-white crystalline powder
Odor: Slight, characteristic
pH: 7.3-7.6 (for 1% solution in water)
Melting Point: 203-205°C (decomposes)
Boiling Point: Not applicable (decomposition before boiling)
Flash Point: Not determined or not applicable for solids
Flammability: Non-flammable under typical conditions, combustible dust in fine particulate form
Solubility: Soluble in water (~130 g/L at 20°C)
Vapor Pressure: Negligible
Vapor Density: Not applicable
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: No data, not expected to pose ignition risk
Decomposition Temperature: >200°C
Bulk Density: 0.65 – 0.85 g/cm³
Chemical Stability: Stable under recommended storage conditions, moisture sensitive
Possibility of Hazardous Reactions: Does not polymerize, not expected to react violently
Conditions to Avoid: Excess heat, direct sunlight, sources of ignition, contact with moisture or strong oxidizers
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Nitrogen oxides, ammonia, carbon monoxide, carbon dioxide under fire conditions
Acute Toxicity: Low toxicity based on oral LD50 in rats (>5000 mg/kg body weight)
Skin Corrosion/Irritation: Mild and reversible irritation possible; not classified as a skin irritant
Serious Eye Damage/Irritation: May cause temporary irritation, no evidence of serious damage
Respiratory Sensitization: No evidence or reports of respiratory sensitization
Germ Cell Mutagenicity: Not identified as a mutagen by available sources
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No specific reproductive toxicity reported
Specific Target Organ Toxicity (Single/Repeated Exposure): No adverse systemic effects identified
Aspiration Hazard: Not recognized as an aspiration hazard
Additional Remarks: Used safely as a dietary supplement for neurological research in some jurisdictions; large amounts may cause discomfort
Ecotoxicity: No evidence of acute toxicity to aquatic life in standard test models
Environmental Fate: Readily biodegradable, does not bioaccumulate significantly
Mobility in Soil: High solubility in water, mobile in aquatic systems, low potential for soil accumulation
PBT/vPvB Assessment: Not identified as persistent, bioaccumulative or toxic
Effect on Microorganisms: Not expected to harm wastewater treatment microbes
Other Adverse Effects: No adverse environmental effect expected in normal use and disposal practices
Waste Treatment Methods: Dispose of contents/container in accordance with local/regional/national regulations
Disposal of Product: Incinerate or landfill at approved facility, do not release into environment
Contaminated Packaging: Rinse containers well, offer for recycling or disposal at registered site
Special Precautions: Never dispose into sewers or municipal waste streams
Other Recommendations: Consult chemical waste specialist if unsure of disposal methods
UN Number: Not regulated as dangerous goods
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Marine Pollutant: Not classified
Special Precautions for Transport: Use sturdy packaging, prevent release of dust in transit, secure loads to avoid spillage
Transport in Bulk: Not subject to bulk transport requirements under MARPOL/IBC code
US TSCA: Listed
EU REACH: Exempt as a naturally occurring substance; not classified as hazardous
Canada DSL/NDSL: Listed
California Proposition 65: Not listed
Other Regulations: No exposure limits set by OSHA, NIOSH, or ACGIH
Chemicals Inventory Status: Present on Australia, Japan, Korea, and China chemical inventories
Workplace Classification: Not regulated for specific workplace hazards, general laboratory safe work practices apply
