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Product Name: Alpha-Ketoglutaric Acid
Chemical Name: 2-Oxoglutaric Acid
Common Synonyms: AKG, 2-Oxopentanedioic acid
CAS Number: 328-50-7
Molecular Formula: C5H6O5
Intended Use: Intermediate in biochemical and clinical processes, research applications, dietary supplements
Contact Information for Supplier: [Supplier contact details and emergency phone number]
Classification: Not classified as hazardous under most regulatory criteria
GHS Signal Word: No mandatory signal word
Hazard Statements: May cause mild skin or eye irritation in sensitive individuals
Pictograms: No pictogram required
Precautionary Statements: Avoid unnecessary contact with skin and eyes, wash hands thoroughly after handling
Other Hazards: Dust generation may cause mild respiratory irritation
Chemical Identity: Alpha-Ketoglutaric Acid
Purity: >98% pure material
Major Ingredients: Alpha-Ketoglutaric Acid
Impurities: Trace inorganic and organic by-products, not considered relevant at concentration present
Inhalation: Move person to fresh air, restore normal breathing, obtain medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected area with water and soap, seek attention if reaction develops
Eye Contact: Rinse cautiously with clean water for several minutes, remove contact lenses if present, continue rinsing, obtain medical supervision if discomfort continues
Ingestion: Rinse mouth with water, seek medical evaluation if large amount swallowed or if symptoms develop
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water jet on powder fires
Specific Hazards: Combustion releases carbon oxides and low molecular weight organic acids
Protective Equipment: Wear full protective gear, self-contained breathing apparatus when exposed to combustion byproducts
Special Procedures: Remove containers from fire zone if safe, avoid inhaling fumes produced by combustion
Personal Precautions: Wear gloves and goggles, avoid production of dust clouds, ensure proper ventilation
Environmental Precautions: Prevent entry into drains, soil, surface water, and sewers
Clean-up Methods: Gather spillage using appropriate tools, transfer to sealed container for disposal, wash spill site with water
Handling: Avoid inhaling dust or contact with eyes and skin, wear suitable protective clothing
Hygienic Practices: Wash hands after handling, avoid eating, drinking, or smoking in laboratory areas
Storage: Store in tightly closed container in a dry, ventilated location, protect from moisture, keep away from incompatible materials such as strong oxidizers
Storage Temperature: Room temperature recommended, low humidity prolongs stability
Exposure Limits: No occupational exposure limits established for α-Ketoglutaric Acid
Ventilation: Use in a well-ventilated area, preferably a fume hood if working with bulk powders
Respiratory Protection: Wear NIOSH-approved mask suitable for powder
Hand Protection: Nitrile or vinyl gloves
Eye Protection: Chemical resistant safety goggles
Skin Protection: Laboratory coat recommended
Other Controls: Emergency eye-wash stations should be accessible in workplaces using this compound
Appearance: White to off-white crystalline powder
Odor: Odorless to faint acidic
Molecular Weight: 146.11 g/mol
Melting Point: 116°C to 120°C
Solubility: Freely soluble in water, sparingly soluble in alcohol
pH (aqueous solution): Approximately 2.5 to 3.0
Boiling Point: Decomposes before boiling
Vapor Pressure: Not applicable (solid at RT)
Density: 1.65 g/cm3
Stability: Stable under normal laboratory conditions
Conditions to Avoid: Moisture, excessive heat, exposure to acids or strong oxidizing agents
Incompatible Materials: Strong bases, oxidizers, reducing agents
Hazardous Decomposition: Forms gaseous carbon dioxide, carbon monoxide, smaller organic acids on overheating or combustion
Polymerization: Does not occur
Routes of Exposure: Inhalation, skin, eye contact, ingestion
Acute Toxicity: Low toxicity based on available data, no LD50 for humans available
Chronic Effects: No known human chronic health hazards
Skin: May cause minor irritation on prolonged or repeated contact
Eye: Dust may lead to mild irritation
Inhalation: High concentration of airborne powder can irritate respiratory tract
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Other Effects: No reproductive or mutagenic effects established by current animal or in vitro tests
Environmental Impact: Not expected to present significant risk at concentrations used in research or industrial settings
Aquatic Toxicity: Data indicate low toxicity to aquatic organisms
Persistence: Rapidly degrades in environmental conditions via microbial metabolism
Bioaccumulation: Unlikely to bioaccumulate due to high water solubility and low lipid solubility
Mobility: Highly mobile in aquatic environments, dilutes readily in water
Waste Disposal Methods: Dispose as non-hazardous laboratory chemical waste, follow local/regional/national guidelines
Container Disposal: Completely empty containers before recycling or disposal, rinse thoroughly
Precautions: Do not discharge into sewers or waterways, avoid dust generation during transfer to waste
UN Number: Not regulated under international transport rules
Transport Hazard Class: Not assigned
Packing Group: Not required
Shipping Name: Alpha-Ketoglutaric Acid
Special Transport Precautions: Protect from physical damage and moisture through secure, sealed packaging
TSCA Listing: Listed
REACH Status: Not specifically registered, low volume chemical
OSHA Hazard Communication: Not regulated as hazardous
Other National Inventories: Listed in EINECS, ENCS, DSL
Labeling Requirements: General chemical safety labeling, caution for powder/dust form
Other Regulations: No SARA, CERCLA, or RCRA reportable thresholds
Community Right-to-Know: Not listed for special reporting
