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Product Name: Zinc Gluconate
Chemical Formula: C12H22O14Zn
CAS Number: 4468-02-4
Synonyms: Gluconic acid, zinc salt, Zinc bis(D-gluconate)
Recommended Use: Nutraceuticals, supplements, food additive, pharmaceutical applications
Manufacturer: [Supplier Information]
Emergency Contact: [Phone and Address]
Classification: Not classified as hazardous by GHS criteria
Physical Hazards: Dust may cause mechanical irritation to respiratory system
Health Hazards: May cause mild skin or eye irritation in sensitive individuals. Inhalation of dust might trigger respiratory tract discomfort
Environmental Hazards: Zinc compounds may be toxic to aquatic life in high concentrations
Label Elements: No pictograms or signal words required by GHS
Precautionary Statements: Avoid breathing dust. Use in well-ventilated areas. Wash thoroughly after handling
Chemical Name: Zinc Gluconate
Common Name: Zinc gluconate
CAS Number: 4468-02-4
Concentration: 98–102% (typical commercial purity)
Impurities: Insignificant trace impurities, food/pharmaceutical grade standards
Molecular Weight: 455.68 g/mol
Inhalation: Remove to fresh air, support breathing if required. Seek medical attention for continued discomfort
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water
Eye Contact: Rinse eyes gently with water for at least 15 minutes, remove contact lenses. Get medical advice if irritation persists
Ingestion: Rinse mouth. If large amounts consumed, drink water to dilute and contact medical personnel for advice
Most Important Symptoms: Mild irritation to eyes, skin, throat possible. Symptoms subside with removal of source
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, foam as needed
Fire Hazards: Zinc gluconate does not burn but thermal decomposition can release irritating fumes
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and standard protective gear
Advice for Firefighters: Avoid inhaling fumes. Stay upwind. Cool containers with water spray if exposed to fire
Hazardous Combustion Products: Oxides of zinc, carbon oxides emitted at high temperatures
Personal Precautions: Avoid generating dust. Ventilate area. Put on protective gloves and respiratory protection if necessary
Environmental Precautions: Prevent large spills entering drains or waterways, as high zinc content can impact aquatic organisms
Cleanup Methods: Collect spilled material with a shovel, broom or vacuum. Place in closed, labeled container for disposal. Clean area with water to remove remaining residues. Avoid creating airborne dust during cleanup
Handling: Manage containers carefully to prevent damage and spillage. Work in areas with sufficient ventilation or fume extraction. In case of dust formation, use appropriate respiratory protection. Practice good hygiene and keep food separate from storage/handling zones
Storage Conditions: Store in tightly closed, labeled containers away from moisture, heat, and direct sunlight. Maintain storage area at ambient temperature, away from incompatible substances such as strong acids and oxidizers. Prevent strong impact or compression on packaging to reduce risk of container rupture. Protect from humidity, which can cause caking or product degradation
Exposure Limits: No specific occupational exposure limits set for zinc gluconate. General dust limit (OSHA PEL for particulates not otherwise regulated): 15 mg/m³ (total), 5 mg/m³ (respirable)
Engineering Controls: Use local exhaust ventilation to minimize airborne dust. Deploy dust extraction systems in bulk transfer zones. Isolate dusty operations when possible
Personal Protective Equipment: Safety goggles for eye protection, gloves for prolonged contact, N95 respirator or similar for dusty environments, lab coat or apron as needed
Hygiene Measures: Wash hands and exposed skin after handling. Do not eat, drink, or smoke during use. Remove contaminated clothing and launder before reuse
Appearance: White or off-white fine crystalline powder
Odor: Odorless
Solubility: Soluble in water (approximately 1g/10mL at 20°C), insoluble in ethanol
pH: Aqueous solution pH around 5.5–7.5 (at 5% w/v)
Melting Point/Freezing Point: Decomposes before melting (approx. >150°C)
Boiling Point: Not applicable
Vapor Pressure: Not volatile
Density: 1.65 g/cm³ (bulk, approximate)
Partition Coefficient: Not available
Evaporation Rate: Not volatile
Flammability: Non-flammable
Decomposition Temperature: Above approximately 150°C
Other Data: Hygroscopic properties possible, may cake if exposed to air and moisture
Reactivity: Zinc gluconate stays chemically stable under recommended conditions. Excessive heat, acid or oxidizer exposure may break down the compound
Chemical Stability: Stable at room temperature, sensitive to excessive humidity and temperature extremes
Possibility of Hazardous Reactions: Will not undergo hazardous polymerization. May react with strong acids to release zinc ions and gluconic acid
Conditions to Avoid: High humidity, strong heat, contact with incompatible materials (acids, oxidizers)
Incompatible Materials: Strong acids, strong oxidizing agents
Hazardous Decomposition Products: Zinc oxides, carbon oxides, potentially irritating smoke and fumes at high temperature
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral LD50 (mice): 3500 mg/kg (literature), low acute toxicity in humans
Skin/Eye Irritation: May cause mild irritation on contact. Prolonged or repeated exposure not known to trigger severe effects
Respiratory Sensitization: Not classified as a sensitizer but dust inhalation can cause discomfort
Ingestion Effects: High doses may induce stomach upset, nausea, or vomiting
Chronic Toxicity: No evidence for carcinogenicity, mutagenicity, or reproductive toxicity at standard exposure levels
Other Information: Dietary zinc intake at appropriate levels considered safe; excessive zinc consumption can disrupt copper absorption and immune function
Aquatic Toxicity: Zinc ions are toxic to aquatic organisms at elevated concentrations. LC50 (fish, zinc salts): varies by species (~0.1–3 mg/L). Zinc gluconate less toxic than zinc sulfate or chloride but high release can change water ecology
Mobility in Soil: Mobile in water, can migrate through soil if heavily spilled
Persistence and Degradability: Gluconate moiety breaks down to environmentally benign products; zinc does not degrade but binds to sediment
Bioaccumulation Potential: Unlikely due to physiological need for zinc but excessive environmental release can bioaccumulate in aquatic organisms
Other Effects: No significant impact anticipated under standard practice, but large spills to waterways could harm aquatic life and water quality
Waste Disposal: Dispose as non-hazardous solid waste unless contaminated with hazardous materials. Follow local, state, and federal waste management regulations. Avoid uncontrolled release to waterways, storm drains, or soil
Container Disposal: Rinse containers thoroughly, render unusable, then discard to approved site. Recycle packaging if possible
Special Precautions: For large-scale disposal, consult a licensed chemical waste disposal service. Prevent zinc gluconate from entering aquatic environments in bulk volume
UN Number: Not regulated as dangerous goods
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not applicable
Proper Shipping Name: Zinc Gluconate
Environmental Hazards: Keep packages secure and dry during transit to prevent leakage and dust generation. Prevent release to the environment during major spills
Special Precautions: Observe standard precautions for bulk powder/pallet loads: stack safely, protect packaging from compression or puncture
Inventory Listing: Listed on TSCA, REACH, AICS, DSL, and other major chemical inventories as a food, pharma, or supplement ingredient
Safety, Health, and Environmental Regulations: Not classified as a controlled substance or subject to special restrictions. Workers should comply with OSHA/NIOSH safety controls for chemical hygiene
Labeling Requirements: No special hazard labels required; advice for safe handling and storage should appear on shipping and storage packaging
SARA Title III, Section 313: Zinc compounds listed; reporting may be needed if large volumes are handled
Other Regulations: Subject to food additive/purity rules under FDA and local authorities for supplements or food use. Handle with care to protect workers and consumers
