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Product Name: Zinc Citrate Food Grade
Chemical Formula: C12H10O14Zn3
Common Synonyms: Trizinc dicitrate, Zinc salt of citric acid
CAS Number: 546-46-3
Recommended Use: Dietary supplement, Food additive, Oral health products
Manufacturer Information: Company name, full address, emergency contact phone number, supplier email & website
Emergency Overview: White to off-white powder with no distinctive odor, mainly used as a nutritional source of zinc in foods and supplements.
Classification: Not classified as hazardous under GHS; not considered a dangerous substance for supply or conveyance
Physical Hazards: May produce dust during handling; can irritate the eyes, skin, and respiratory tract in high concentrations
Health Hazards: Chronic ingestion may cause gastrointestinal disturbances; inhalation of dust may cause respiratory irritation
Environmental Hazards: Toxic to aquatic organisms in extremely high concentrations, not persistent in soil or water at low levels
Risk Phrases: Not subject to risk phrase labeling but care should be taken during bulk handling
Precautionary Statements: Avoid breathing dust; use with adequate ventilation; avoid unnecessary contact with skin and eyes
Chemical Name: Zinc Citrate Trihydrate
CAS Number: 546-46-3
Concentration: Minimum 98% purity as zinc citrate trihydrate by mass
Impurities: Trace amounts of heavy metals below regulatory thresholds; specific tests for lead, arsenic, cadmium, mercury required under food additive standards
Other Ingredients: No preservatives or additives typically present in the food-grade material
General Advice: Move affected person to fresh air, obtain medical attention if symptoms persist
Inhalation: Remove to fresh air and keep at rest; seek medical advice if breathing difficulty develops
Skin Contact: Wash with soap and plenty of water; medical attention is not typically required unless irritation continues
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present; continue rinsing
Ingestion: Rinse mouth, give water to drink, do not induce vomiting; get medical advice if large quantities are swallowed or symptoms occur
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide extinguishing equipment
Unsuitable Media: Do not use strong water jets as dust or slurry may spread
Special Hazards: Material is not flammable; may decompose under intense heat to produce zinc oxide fumes and oxides of carbon
Firefighter Protection: Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes; avoid inhaling dust or vapors from heated material
Explosion Data: Not explosive under normal handling; fine dust may cause dust clouds, so avoid sources of ignition in dust-rich environments
Personal Precautions: Evacuate area, ventilate, avoid breathing dust; wear suitable PPE including gloves, safety goggles, dust mask or respirator if ventilation is inadequate
Environmental Precautions: Avoid release to the environment, particularly water bodies, in large amounts
Cleanup Procedures: Sweep up powdered material carefully to avoid dust formation; collect in containers for disposal; wash residual traces with water but prevent runoff to drains
Containment Methods: Cover spill with plastic sheet if necessary, keep containers closed
Notification Procedures: Report major spills to relevant environmental authorities according to local rules
Safe Handling: Use local exhaust or ventilation to minimize dust; wear personal protection; use only in permitted, food-grade certified environments; minimize dust accumulation on surfaces
Storage Requirements: Store in a cool, dry, well-ventilated place away from strong acids, alkalis, and foodstuffs for direct consumption
Container Integrity: Keep original containers tightly closed; avoid contact with incompatible substances; ensure clear labeling
Other Precautions: Do not eat, drink, or smoke while handling; wash hands thoroughly after use; use dedicated utensils for food-grade materials
Occupational Exposure Limits: No established OEL for zinc citrate, but follow OSHA general dust limits (15 mg/m3 total dust; 5 mg/m3 respirable fraction)
Engineering Controls: Install local exhaust ventilation, dust extraction, or process enclosures to limit airborne dust
Respiratory Protection: Use NIOSH-approved dust masks or respirators if dust exceeds limits or workplace ventilation is insufficient
Skin Protection: Use chemical-resistant gloves, long sleeves, and protective clothing
Eye and Face Protection: Wear safety glasses with side shields or goggles to protect from splashes or airborne powder
Hygiene Practices: Wash skin after handling, remove contaminated clothing, observe good workplace hygiene
Appearance: White or almost white odorless powder
Odor: Odorless
pH (1% aqueous suspension): 6.0-8.0
Melting Point: Not applicable, decomposes before melting
Solubility in Water: Slightly soluble (<25 mg/L at 20°C)
Specific Gravity: 2.3 g/cm3
Bulk Density: 0.5-0.7 g/cm3
Particle Size: 80-150 microns typically
Boiling Point: Not relevant
Vapor Pressure: Negligible
Flammability: Not flammable
Explosive Properties: Not classified as explosive
Chemical Stability: Stable under normal conditions of storage and use in original packaging
Reactivity: Unreactive at ambient temperature, reacts with strong acids to produce citric acid and zinc salts
Hazardous Reactions: Avoid mixing with strong oxidizers or strong acids, which could accelerate decomposition
Decomposition Products: Zinc oxide and carbon oxides may be released in case of fire or thermal degradation
Conditions to Avoid: Excessive heat, moisture, contact with incompatible chemicals
Incompatibles: Strong acids, strong bases, oxidizing agents
Acute Toxicity: Oral exposure: relatively low toxicity; LD50 values for rats: >2000 mg/kg; not acutely toxic in typical dietary doses
Skin Irritation: Mildly irritating in susceptible individuals
Eye Irritation: May cause transient irritation
Respiratory Effects: Dust inhalation may cause irritation of the respiratory tract; symptoms can include coughing or sneezing
Sensitization: Not known to cause dermal or respiratory sensitization
Chronic Effects: Chronic exposure to high doses can affect mineral balance, especially copper and iron absorption
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity / Teratogenicity: No evidence from animal studies at doses relevant for food use
Aquatic Toxicity: Harmful to aquatic organisms at high concentrations, not expected to be hazardous in dilute environmental discharges
Terrestrial Toxicity: Not expected to persist or bioaccumulate in soil; zinc is a plant micronutrient in trace amounts
Persistency and Degradability: Biodegradable under environmental conditions; citrate moiety breaks down rapidly
Mobility in Soil: Limited, but runoff from large spills may lead to short-term increases in zinc levels
Bioaccumulation: Unlikely due to low mobility and essential nature of zinc in trace levels
Other Adverse Effects: Avoid concentrated releases to surface waters or sewage systems
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations for non-hazardous chemical waste
Container Disposal: Rinse containers thoroughly, then recycle or dispose of as approved by authorities
Disposal of Product: May be landfilled at approved sites, incineration is not typically required; avoid contamination of soil and water
Precautions: Do not discharge large volumes into sewers or watercourses; unused product and contaminated packaging must be treated as solid waste
UN Number: Not regulated as a dangerous good by road, rail, air, or sea
Proper Shipping Name: Non-hazardous, food-grade zinc citrate
Transport Hazard Class: Not classified as hazardous
Packing Group: Not applicable
Special Precautions for Transport: Ship in sealed packaging, protect from moisture, avoid contamination with foodstuffs
Label Requirements: No special labels required beyond clear product and safety marking
Food Additive Regulations: Approved for use in food and dietary supplements in many countries; subject to purity requirements and heavy metal limits
Labeling Standards: Must meet FDA, EFSA, or equivalent specifications for food-grade ingredients; requires clear batch and lot traceability
Workplace Regulations: Workers must comply with general chemical hygiene standards, OSHA rules for dust, and local workplace safety legislation
Environmental Regulations: No special requirements under US EPA toxic substances rules at food use concentrations; site-specific limits may apply in other regions
Other Standards: Subject to REACH in the EU as a substance used in industrial processes and as a food additive
