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Material Safety Data Sheet: Zein

Identification

Product Name: Zein
Chemical Name: Zein (corn protein)
CAS Number: 9010-66-6
Use: Film-forming agent, coatings for pharmaceuticals, food, biodegradable plastics
Manufacturer Information: Supplier and address details available on batch label
Emergency Telephone: Provided on shipment paperwork according to region

Hazard Identification

Classification: Not classified as hazardous according to OSHA, EU CLP or GHS standards
Health Hazards: Dust may cause respiratory tract and eye irritation
Signal Word: None required
Pictogram: Not applicable
Precautionary Statements: Avoid creating dust; ensure adequate ventilation; limit contact with eyes and skin
Other Hazards: Fine powders can form explosive mixtures with air under certain conditions

Composition / Information on Ingredients

Ingredient: Zein protein
Chemical Formula: Variable, composed primarily of prolamin proteins derived from corn
Concentration: 90 - 100% zein
Impurities: Trace carbohydrates, moisture (up to 10%), negligible fat content

First Aid Measures

Inhalation: Remove to fresh air, rinse mouth if dust inhaled, seek medical help if symptoms persist
Skin Contact: Wash with soap and water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get attention for persistent irritation
Ingestion: Rinse mouth, drink water, seek medical attention for discomfort or for pre-existing sensitivities

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Hazards: May release carbon dioxide and carbon monoxide under fire
Specific Methods: Remove containers from fire area if safe, cool surrounding area with water
Protective Equipment: Firefighters use self-contained breathing apparatus, full protective clothing
Explosion Risk: Zein dust can form explosive mixtures in air; avoid dust accumulation

Accidental Release Measures

Personal Protection: Wear dust mask, goggles, gloves
Spill Cleanup: Use dustless method or HEPA vacuum, dampen with water to reduce dust
Environmental Precautions: Avoid discharge into drains, watercourses
Reporting: Comply with local notification requirements if large quantities released

Handling and Storage

Safe Handling: Minimize dust generation, handle in ventilated area, use grounding for equipment
Storage Conditions: Store in cool, dry, well-ventilated space in tightly sealed containers
Incompatible Materials: Strong oxidizers, acids
Special Precautions: Keep away from ignition sources, prevent static discharge

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational limits set, observe nuisance dust limits (OSHA PEL: 15 mg/m³ total, 5 mg/m³ respirable)
Ventilation: Use local exhaust or general ventilation for dust control
Respiratory Protection: Dust respirator in poorly ventilated areas or large-scale operations
Skin Protection: Gloves when contact likely
Eye Protection: Safety goggles recommended when handling bulk powder
Hygiene Measures: Wash thoroughly after handling, avoid eating or drinking during use

Physical and Chemical Properties

Appearance: Yellow-white to tan powder
Odor: Slight, characteristic
Odor Threshold: Not established
pH: Slightly acidic
Melting Point: 190°C (decomposes)
Boiling Point: Not applicable
Flash Point: Not determined due to solid form
Evaporation Rate: Not applicable
Flammability: Not highly flammable, but dust may ignite
Explosion Limits: Lower: approx. 30 g/m³ (dust in air)
Vapor Pressure: Not applicable
Solubility: Insoluble in water, soluble in 80% ethanol, acetone, aqueous ammonia
Partition Coefficient: Not determined
Auto-ignition Temperature: Approx. 400°C
Decomposition Temperature: Above 190°C
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal use, sensitive to moisture, may clump if wet
Reactivity: Low chemical reactivity under normal conditions
Conditions to Avoid: Sources of ignition, moisture, strong oxidizers
Hazardous Decomposition: Burning produces CO₂, CO, nitrogen oxides
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Not acutely toxic as per available data
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Health Effects: Dust irritation of respiratory tract, eyes, or skin
Chronic Effects: No studies showing chronic toxicity, no carcinogenic classification
Special Sensitivities: Not known to be allergenic, but food-grade corn protein allergies may apply
Mutagenic or Reproductive Effects: Not identified

Ecological Information

Environmental Fate: Biodegradable protein, breaks down in soil and water
Aquatic Toxicity: No data suggesting harm to aquatic systems
Mobility: Not mobile as bulk powder
Persistence and Degradability: Rapidly degrades by natural processes
Bioaccumulation: Not expected to bioaccumulate

Disposal Considerations

Waste Disposal: Dispose of in accordance with local, state, and federal laws, treat as non-hazardous waste if not contaminated
Packaging Disposal: Use unsoiled containers for recycling or disposal
Special Instructions: Do not discharge into water sources, avoid airborne dust during disposal

Transport Information

UN Number: Not classified as dangerous for transport
UN Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Protect from moisture and rough handling in transit, ship in sealed container

Regulatory Information

OSHA: Not listed as hazardous
TSCA (US): Listed
DSL (Canada): Listed
REACH (EU): Exempt as naturally occurring substance
Other Regulations: Not subject to chemical-specific notification or labeling
Label Elements: No hazard labeling required under GHS, supply common name and safety advice
Restrictions: None specific, other than food/pharmaceutical purity requirements