Wusu, Tacheng Prefecture, Xinjiang, China admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:



Zaltoprofen Material Safety Data: A Down-to-Earth Look

Identification

Name: Zaltoprofen
Chemical Formula: C17H14O3S
Common Use: Non-steroidal anti-inflammatory drug for pain relief
Appearance: White to off-white crystalline powder
Odor: Odorless
Other Names: Not widely marketed globally under other trade names
Distinctive Features: Structural resemblance to other propionic acid derivatives

Hazard Identification

Main Risks: Irritation to eyes, skin, and respiratory tract on direct contact
Health Hazards: Can provoke gastrointestinal discomfort, potential allergic skin reactions in some individuals, aggravation of pre-existing asthma
Environmental Hazards: Spillage into waterways can disrupt aquatic ecosystems
Chronic Effects: Overuse linked to renal impairment and cardiovascular concerns
GHS Classification: This compound carries risk statements around organ toxicity and allergic response

Composition / Information on Ingredients

Main Constituent: Zaltoprofen (over 98% by weight)
Impurities: Trace amounts of process-related organic by-products
Physical Form: Highly pure, particulate solid
Nature of Mixture: Typically processed as a single active component with few excipients during preparation for clinical use

First Aid Measures

Inhalation: Move to fresh air, monitor breathing, seek medical attention for discomfort
Skin Contact: Wash thoroughly with water and mild soap, remove contaminated clothing
Eye Contact: Rinse under running water for at least fifteen minutes, consult an ophthalmologist if irritation continues
Ingestion: Rinse mouth, avoid vomiting unless instructed by medical personnel, get prompt medical advice
Notes for Healthcare Providers: Monitor for adverse reactions specific to NSAIDs, including gastrointestinal upset or allergic flare-ups

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam
Unsuitable Media: Water jets may spread powder contamination
Hazardous Combustion Products: Sulfur oxides, carbon oxides, potentially irritating fumes
Protective Precautions: Full protective clothing and self-contained breathing apparatus recommended for responders
Special Notes: Move containers away from fire zone if possible without risk, ensure firewater remains uncontaminated

Accidental Release Measures

Personal Precautions: Use gloves, eye protection, provide respiratory protection in areas with dust
Cleanup Methods: Control dust with damp material, collect spilled material in suitable container for disposal
Environmental Safeguards: Protect against spillage into drains, soils, and waterways
Ventilation: Use good ventilation to avoid inhalation risks for those cleaning up
Waste Management: Gather residue in chemically compatible containers for controlled disposal

Handling and Storage

Handling Practices: Avoid dust formation, keep away from food and beverages, do not breathe powder
Hygiene: Wash hands before breaks and after handling, keep clothes clean
Safe Storage Conditions: Keep containers tightly sealed, store in a dry, well-ventilated environment, protect from light and heat sources
Incompatibles: Store away from oxidizers, acids, and sources of ignition
Segregation: Place away from incompatible pharmaceuticals and chemicals

Exposure Controls and Personal Protection

Engineering Controls: Ensure local exhaust systems operate where powder is handled
Personal Protective Equipment: Nitrile gloves, goggles or safety glasses, laboratory coats, approved respirator for airborne particles
Control of Occupational Exposure: Limit exposure time, implement closed-system handling if available
Hygiene Measures: Do not eat, drink, or smoke in handling area, wash contaminated skin after work

Physical and Chemical Properties

Physical State: Solid, crystalline
Color: Ranges from white to very pale cream
Melting Point: Around 124°C
Solubility: Slightly soluble in water, more soluble in organic solvents like ethanol
Molecular Weight: 298.36 g/mol
pH (in aqueous solution): Slightly acidic
Odor: None
Vapor Pressure: Negligible at room temperature

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Thermal Decomposition: Can release toxic gases at high temperatures
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Polymerization: Does not undergo hazardous polymerization
Reactivity Notes: Product integrity holds up well under standard pharmaceutical conditions until expiry

Toxicological Information

Routes of Exposure: Inhalation, skin contact, ingestion
Acute Effects: Stomach distress, possible allergic reactions, nasal passage irritation if inhaled
Chronic Effects: Long-term use linked to ulcer risk, kidney impacts, rare blood count changes
Sensitization: Contact may provoke skin sensitization in susceptible individuals
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a confirmed carcinogen
Other Effects: Laboratory animal studies suggest low acute oral toxicity at therapeutic doses

Ecological Information

Environmental Fate: Persistent in aquatic systems due to low water solubility
Toxicity to Aquatic Life: May harm fish and aquatic invertebrates in concentrated doses
Mobility: Tends to bind with soil and sediment; unlikely to reach groundwater easily
Bioaccumulation: Low potential for bioaccumulation
Degradation: Breaks down slowly by abiotic and biotic means

Disposal Considerations

Waste Treatment: Follow all local drug disposal guidelines, avoid flushing into waterways
Disposal of Containers: Triple-rinse containers, deface labels, place with chemical waste
Precautionary Steps: Seek chemical waste disposal through licensed contractors to avoid environmental harm
Other Solutions: Encourage take-back programs and collaborations with hospitals or clinics to centralize unused stock disposal

Transport Information

Classification: Transported as non-hazardous under most regulations for pharmaceutical solids
Packaging: Use moisture-proof, tamper-evident containers
Labeling: Include clear identity, hazard warnings when shipping in bulk
Handling During Transit: Guard against breakage, secure against spillage in transit to prevent both waste and exposure
Regulatory Transport Restrictions: Not classified under dangerous goods for air, road, or sea in most developed economies

Regulatory Information

Legal Status: Prescription-only medicine in countries where approved
Workplace Safety: Must comply with regional occupational health statutes
Environmental Compliance: Subject to chemical waste rules under local environmental protection authorities
Pharmacological Oversight: Approved as an NSAID in limited markets, subject to varying approvals depending on jurisdiction
Other Requirements: Mandates secure storage, monitoring and record-keeping per healthcare regulation