© 2026 Sinochem Nanjing Corporation,
All Right Reserved
3-Cyclohexylaminopropanesulfonic Acid Sodium Salt, sometimes called CAPS-Sodium Salt, belongs to a class of so-called Good’s buffers, valued for their stability and broad use in biochemistry and molecular biology. The chemical acts as a buffer, meaning it helps keep the pH steady in solutions, which often matters when working with proteins and enzymes. In my experience inside a biochemistry lab, stable pH means experimental data stays reliable, and fewer surprises pop up along the way. The sodium salt form swaps out the hydrogen in the sulfonic acid group for sodium, which usually boosts solubility and lets scientists make standard solutions faster without fuss.
CAPS-Sodium Salt turns up as a solid in most labs, usually as a white powder, crystalline solid, or sometimes as small flakes. This powder dissolves quickly in water, giving a clear solution, which saves time during set up for electrophoresis or western blotting. Its molecular formula is C9H18NNaO3S, and the structure shows a cyclohexyl group attached to a propanesulfonic acid, with an amine tucked onto the chain. Its molecular weight lands at about 255.3 g/mol. Density can shift with hydration level and form, but measuring around 1.25 g/cm³ for the solid isn’t uncommon. With a pKa close to 10.4 at 25°C, CAPS-Na buffers well in the alkaline pH range, which comes in handy during certain protein purification or enzymatic assays. Such specific alkalinity beats common buffers when handling proteins that lose stability at lower pH.
Scientists, production teams, and technical staff find CAPS-Sodium Salt in packs labeled as flakes, powder, or occasionally small pearls. Some suppliers also offer it in solution, usually measured in liters for quick batching. In most cases, pouring powder directly into the buffer tank and stirring does the trick, so prepping a working solution can take minutes instead of hours. The material acts as a chemical pH stabilizer in both solution and solid phase, and in some cases, its crystalline nature helps with accurate weighing for analytical work. Its use stretches into chromatography and electrophoresis, especially during protein or nucleic acid separation under alkaline conditions. People focused on diagnostics, drug research, or even manufacturing rely on proper raw materials like CAPS-Na to maintain reproducible results.
The purity for CAPS-Sodium Salt usually hits above 99% for analytical grade material, with trace metals and water content kept minimal by most reputable suppliers. Labs trust product labels to show exact specifications, covering moisture, chloride, sulfate, and insoluble matter. Not every supplier matches detail for detail, but higher quality lots list every contaminant, which gives peace of mind when health, safety, or experimental integrity matter. The HS Code for CAPS-Na lands at 2922199090—helpful for import and export paperwork, customs, and global shipping. Consistent identification under its specific HS Code cuts down on confusion and helps speed logistics.
Like many synthetic chemicals used in research and manufacturing, CAPS-Sodium Salt deserves careful handling. The chemical does not count among the “extremely hazardous” by most standards, but dust or solution can irritate eyes, skin, or respiratory tract if mishandled. Direct ingestion or large splashes pose genuine harmful risks, especially in high concentration. Standard material safety data sheets (SDS) call for gloves, goggles, and working in a well-ventilated space. I’ve learned that labeling bottle tops and keeping an updated SDS file close by stops accidents before they start—especially when training new lab members. If spills happen, sweeping powder into proper waste containers and flushing residues with plenty of water keeps people safe and the workspace clean.
Buffer chemicals like CAPS-Na shape the backbone of daily work in genomics, diagnostics, and protein engineering. Ensuring every shipment meets reliability standards starts with transparent documentation, clear product grades, and robust distribution networks. Suppliers can tighten quality controls, reporting not only purity but trace contaminants and stability data. For end-users, using closed systems when possible, investing in dust-free dispensers, and online inventory management all make handling processes safer and more economical. Open access to regulatory data, application guides, and technical support matters too—especially as more countries grow their research efforts and scale up reagent production. It boils down to product quality, good communication, and proper training, as every step matters from raw material to final experiment.
