© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Vitamin D2
Synonyms: Ergocalciferol
Chemical Formula: C28H44O
Molecular Weight: 396.65 g/mol
CAS Number: 50-14-6
Manufacturers: Listed by major chemical suppliers in nutritional and pharmaceutical industries
Intended Use: Nutritional supplement, food fortification, pharmaceutical ingredient
Contact Information: Found in manufacturer's technical documentation
Emergency Phone: Provided by manufacturer or supplier's safety department
GHS Classification: Category 2 for reproductive toxicity, acute toxicity (oral, dermal, inhalation) not classified under standard handling
Signal Word: Warning
Hazard Statements: Toxic to reproduction, may be harmful if swallowed in large quantities, can cause hypercalcemia on chronic overexposure
Pictogram: Health hazard
Precautionary Statements: Avoid inhalation and ingestion, use in well-ventilated area, wear personal protection
Chemical Name: Ergocalciferol
Concentration: 100% pure or diluted in various carriers for formulations
Impurities: Residual solvents (trace), product stabilizers possible in commercial lots
Allergens: None intrinsic to synthetic/USP grade
Additives: May include powder carriers or stabilizers depending on supplier
Inhalation: Move person to fresh air, seek medical attention for persistent symptoms
Skin Contact: Wash skin with soap and water, remove contaminated clothing, medical consultation for irritation
Eye Contact: Flush with water several minutes, seek medical help if irritation continues
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical authority, monitor for symptoms of overdose (nausea, confusion, weakness)
Symptoms: Hypercalcemia (thirst, confusion, nausea), may develop after chronic overexposure or accidental ingestion of large doses
Flammability: Slight fire hazard in finely divided form or bulk when exposed to flame
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, other toxic gases on decomposition
Special Protective Equipment: Full protective gear and self-contained breathing apparatus recommended for all fires involving chemicals
Firefighting Instructions: Isolate area, approach from upwind, use standard firefighting techniques
Personal Protection: Wear gloves, safety glasses, and dust mask
Environmental Precautions: Avoid soil, water, and drain contamination, contain and absorb spills at once
Cleanup Methods: Use inert absorbent material, sweep up using non-sparking tools, place in closable containers for approved disposal
Decontamination: Rinse area with ample water after removal of bulk material, ventilate affected space
Handling Precautions: Avoid dust development, use in well-ventilated areas, minimize contact with eyes, skin, and clothing
Hygienic Practices: Wash hands after handling, separate from foods and feedstuffs
Storage Conditions: Store in tightly-sealed container, cool, dry, and dark location, ideal temperature below 25°C, protect from light
Incompatibilities: Strong oxidizers, acids, bases, moisture, exposure to sunlight
Special Requirements: Segregate from incompatible chemicals and keep away from children and unauthorized personnel
Engineering Controls: Local exhaust or fume hood for bulk handling, general ventilation where possible
Habitual Monitoring: Inspect airborne concentrations when working with large quantities, use particulate mask as required
Personal Protective Equipment: Gloves (nitrile, latex), safety glasses or goggles, protective lab coat or apron
Respiratory Protection: Dust mask or respirator for powder handling
Environmental Controls: Prevent particles from entering the environment, abide by local safety protocols
Appearance: White to off-white, crystalline or powder
Odor: Practically odorless
Odor Threshold: Not applicable or determined
pH: Not applicable (practically insoluble in water)
Melting Point: 115–118°C
Boiling Point: Not determined, decomposes
Flash Point: >100°C (no significant data for solid formulation)
Solubility: Practically insoluble in water, soluble in alcohol, acetone, fats, and oils
Partition Coefficient (n-octanol/water): Log Kow approximately 8.8
Vapor Pressure: Negligible at room temperature
Density: 0.95–1.00 g/cm³
Viscosity: Not applicable for solid
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal conditions for storage and use
Hazardous Reactions: May react with strong oxidizers, acids, bases
Decomposition Products: Toxic fumes, carbon monoxide, carbon dioxide on excessive heating or combustion
Conditions to Avoid: Prolonged light, heat, humidity, exposure to air or strong chemicals
Acute Toxicity: LD50 (oral, rat) approximately 10–50 mg/kg
Chronic Toxicity: Prolonged exposure leads to hypercalcemia, renal impairment, vascular calcification, symptoms of vitamin D overdose start from 50,000 IU/day in adults
Carcinogenicity: Not considered carcinogenic by IARC, NTP, or OSHA at typical exposure levels
Reproductive Toxicity: Risk of fetal toxicity and teratogenicity at pharmacological doses
Sensitization: Not known as a skin or respiratory sensitizer
Mutagenicity: Tests indicate no mutagenic potential in standard models
Ecotoxicity: Expected very low, not acutely toxic to aquatic life at low concentrations, rapidly biodegradable
Persistence and Degradability: Readily degraded by sunlight and microorganisms in soil and water
Bioaccumulation: Unlikely due to rapid metabolism in environment
Mobility in Soil: Low, partitions strongly to organic material
Other Effects: Avoid bulk disposal into waterways and municipal sewage due to possible nutrient loading
Waste Treatment Methods: Dispose through licensed chemical waste contractors or incineration, follows municipal and local regulations
Container Disposal: Triple rinse containers, dispose as hazardous waste if contaminated
Precautions: Do not allow into soil, rivers, or drains
Recycling: Not considered feasible for bulk product
UN Number: Not regulated as a hazardous material for air, sea, or road transport
Proper Shipping Name: Vitamin D2, Ergocalciferol
Transport Hazard Class: None assigned
Packing Group: Not required
Marine Pollutant: Not classified
Special Precautions for Users: Protect product from moisture, sunlight, and mechanical damage during transit
Other Information: Follow all regulations for handling chemicals in transit, label as a pharmaceutical ingredient
International Inventories: Listed in TSCA (USA), DSL/NDSL (Canada), EINECS (EU), AICS (Australia), ENCS (Japan)
OSHA Standard: Not specifically regulated, control exposure as for nuisance dusts
SARA Title III: Not regulated under Sections 302, 304, or 313
REACH Registration: Exists for medicinal and nutritional use categories
FDA: Approved as food additive and pharmaceutical ingredient
California Proposition 65: Not listed
WHMIS (Canada): Not classified as hazardous
Other Regulations: Must follow GMP for food and pharma workplaces, occupational exposure controls depend on specific workplace
