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Product Name: Valeryl Chloride
Chemical Formula: C5H9ClO
CAS Number: 638-29-9
Synonyms: Pentanoyl chloride, n-valeryl chloride
Intended Use: Intermediate for organic synthesis, pharmaceutical research, agrochemical manufacturing
Manufacturer’s Information: Refer to current label and Safety Officer for contact details
Emergency Phone: Contact local poison control and fire brigade for immediate assistance
Classification: Flammable liquids (Category 3), Acute toxicity (Category 3, inhalation), Skin corrosion/irritation (Category 1B), Eye damage/irritation (Category 1), Specific target organ toxicity, single exposure (Category 3, respiratory tract)
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, triggers respiratory irritation, toxic by inhalation or swallowing, liquid and vapors are flammable
Pictograms: Corrosive, Skull and Crossbones, Flame, Exclamation Mark
Precautionary Statements: Avoid all contact, use only with adequate ventilation, never inhale vapors, keep away from sparks or flame sources, store in tightly closed containers
Chemical Name: Pentanoyl chloride
CAS Number: 638-29-9
Concentration: ≥98% (by weight)
Impurities: Less than 2% hydrocarbons or other chlorinated organics
Substances Present: No additional hazardous ingredients specified above cutoff limits for reporting
Inhalation: Move person to fresh air immediately, give oxygen if breathing is difficult, avoid mouth-to-mouth if rescuing, seek medical attention without delay
Skin Contact: Flush skin using running water for at least 30 minutes, remove contaminated clothing, use soap only if skin remains oily, do not scrub, seek urgent medical attention
Eye Contact: Wash eyes with water or saline for at least 30 minutes continuously, lift eyelids regularly to flush entire area, do not use neutralizing agents, call for ophthalmologist intervention quickly
Ingestion: Do not induce vomiting, rinse mouth with water if person is conscious, never give anything by mouth to an unconscious individual, get medical attention quickly
General Advice: Ensure first responders avoid self-exposure through full personal protection
Suitable Extinguishing Media: Use dry chemical, water spray, alcohol-resistant foam, or carbon dioxide, avoid direct water jets which may spread the substance
Specific Hazards: Releases hydrogen chloride and phosgene upon combustion, may emit pungent and toxic vapors, flammable liquid and vapor
Protective Equipment: Full self-contained breathing apparatus required, fire-resistant chemical splash suit, keep product drums cool using water spray from a safe distance
Firefighting Advice: Approach from upwind, evacuate unnecessary personnel, contain runoff, notify authority if water supply becomes contaminated
Personal Precautions: Use chemical splash goggles, acid-resistant gloves, full face shield, and impervious clothing, avoid all inhalation or skin contact
Emergency Procedures: Evacuate area, ventilate space, control ignition sources, consult safety team before entry
Environmental Precautions: Prevent spills from reaching soil, surface water, and drains, inform environmental authorities if major leak occurs
Methods for Cleanup: Neutralize small spills with sodium carbonate or slaked lime, absorb using dry inert material like sand, shovel into approved waste container, seal and label before disposal
Safe Handling: Only handle in spark-free, well-ventilated chemical fume hoods, avoid static discharge, use proper chemical personal protective equipment at all times
Hygiene Practices: Never smoke, eat, or drink near open product, always wash thoroughly after handling, keep work clothes separate from street clothing
Storage Conditions: Keep containers tightly closed, store in dry and cool dedicated chemical storage, segregate away from water, alcohols, amines, bases, and oxidizers, label tanks and rooms with hazard indicators
Incompatible Materials: Avoid all contact with water or moist air, reactive metals, strong bases, oxidizing agents, hydroxides, or ammonia
Control Parameters: No occupational exposure limits set by OSHA or ACGIH as of latest revision, suggested ceiling values of 1 ppm (manufacturer’s recommendation)
Engineering Controls: Chemical fume hoods, dedicated exhaust ventilation, closed systems for transfers, explosion-proof electrical systems in handling areas
Personal Protective Equipment (PPE): NIOSH-approved air-purifying or supplied-air respirator, chemical-resistant gloves (Viton or butyl rubber preferred), full-face shield, chemical splash goggles, acid-resistant apron and boots
Monitoring: Regular workplace air monitoring, medical surveillance for repeated exposure situations
Appearance: Clear to yellowish liquid with sharp, suffocating odor
Odor: Pungent, irritating
P.H: Not applicable (reacts with water)
Melting Point: −65 °C
Boiling Point: 129 °C (at 760 mm Hg)
Flash Point: 38 °C (closed cup)
Vapor Pressure: 13 mm Hg at 20 °C
Solubility: Reacts fiercely with water, soluble in most organic solvents
Relative Density: 0.97 g/cm3 (20 °C)
Viscosity: 0.77 mPa·s (20 °C)
Partition Coefficient: log Kow estimated 2.4-2.7
Autoignition Temperature: 220 °C
Explosive Properties: Not explosive, forms flammable mixtures in air
Chemical Stability: Stable only in tightly sealed containers under dry, inert gas atmosphere, otherwise decomposes slowly, especially in moist air
Reactivity: Fiercely reactive with water, alcohols, strong bases, hydroxides, and amines, rapidly forms hydrogen chloride and corrosive vapors
Hazardous Decomposition Products: Hydrogen chloride, phosgene, pentanoic acid under heating or combustion
Conditions to Avoid: Avoid moisture, open flames, temperatures above flash point, materials incompatible with acid halides
Routes of Exposure: Absorbed rapidly by inhalation, skin contact, ingestion, or splashes to eyes
Acute Toxicity: Oral LD50 (rat): 252 mg/kg, Inhalation LC50 (rat, 4h): 260 ppm, Dermal LD50 (rabbit): 1,100 mg/kg
Chronic Effects: Prolonged or repeated exposure can cause severe respiratory inflammation, chronic bronchitis, dermatitis, corneal damage
Symptoms of Exposure: Severe burning sensation in mouth, throat, eyes, chemical burns, coughing, shortness of breath, nausea
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No current data showing carcinogenicity, mutagenicity, or reproductive toxicity effects as per IARC, NTP, OSHA, or EU classifications
Ecotoxicity: Toxic to aquatic organisms due to low LC50 values (fish: 11 mg/L, 96 h), harmful to invertebrates and microflora through acidification of water
Mobility: Volatile, vaporizes readily and can be transported with wind, hydrolyzes rapidly in presence of water to pentanoic acid and hydrogen chloride
Persistence and Degradability: Rapid hydrolysis means environmental compartments least likely to see persistent residues beyond days
Bioaccumulation Potential: Low bioaccumulation in aquatic life due to quick breakdown
Other Adverse Effects: Can lower pH drastically on release to water bodies, harming aquatic and plant life, avoid any uncontrolled environmental discharges
Waste Treatment Methods: Neutralize under controlled conditions using soda ash or calcium hydroxide in a fume hood prior to any further treatment
Disposal Containers: Use acid-resistant, labeled containers with sealed closures, do not reuse empty bottles
Special Precautions: Consult local hazardous waste disposal contractor for incineration or landfill, confirm compliance with national and local regulations
Contaminated Packaging: Rinse triple with water (under local guidelines), neutralize washings, label as hazardous waste
UN Number: 1813
Proper Shipping Name: Valeryl chloride
Hazard Class: 3 (Flammable liquids), 8 (Corrosive substances)
Packing Group: II
Labels Required: Flammable liquid, Corrosive
Environmental Hazards: Marine pollutant (if over threshold amount)
Special Transport Precautions: Secure upright, keep modules dry, deliver by authorized carriers with hazmat clearance, follow emergency response guidebook instructions for chemical spills in transit
Inventory Status: Included in TSCA (USA), EINECS/ELINCS (Europe), DSL (Canada), ENCS (Japan); always verify current status before shipping internationally
OSHA: Hazardous chemical, subject to hazard communication standard
SARA Title III: Section 313 listed if workplace threshold exceeded
REACH: Requires registration for manufacture, import, or use above minimum tonnage levels, Safety Data Sheet must accompany all shipments in EU
Other Regulation References: Refer to national transport, waste control, and workplace health and safety codes for handling obligations; consult MSDS for local variations in country-specific regulation
