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Product Name: Tauroursodeoxycholic Acid
Synonyms: Tudca; TUDCA; Tauro-ursodeoxycholic acid
CAS Number: 14605-22-2
Recommended Use: Research, pharmaceutical ingredient, biochemical studies
Supplier Details: Name, address, phone number, emergency contact
Classification: Not classified as hazardous under GHS criteria
Signal Word: Not applicable
Hazard Statements: No known significant effects or critical hazards
Pictograms: None
Precautionary Statements: Avoid dust formation; use personal protective equipment
Other Hazards: May cause mild skin or eye irritation upon direct contact
Chemical Identity: Tauroursodeoxycholic Acid
Concentration: 95–100% active ingredient
Molecular Formula: C26H45NO6S
Molecular Weight: 499.7 g/mol
Impurities: Trace organic or inorganic compounds below reporting threshold
Inhalation: Move to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash with soap and water; remove contaminated clothes
Eye Contact: Rinse cautiously with water; remove contact lenses if present and easy; continue rinsing
Ingestion: Rinse mouth, drink water, get medical advice if feeling unwell
Symptoms: May cause mild irritation to skin, eyes, respiratory tract; unlikely to cause serious harm under normal conditions
Notes to Physician: Symptomatic treatment; no specific antidote known
Suitable Extinguishing Media: Water spray, carbon dioxide, foam, dry chemical extinguishers
Unsuitable Media: High volume water jet can spread powders
Special Hazards: Fine dust can form explosive mixtures with air; thermal decomposition may release toxic fumes
Protective Equipment: Self-contained breathing apparatus, full protective gear
Other Information: Cool containers exposed to fire with water spray; prevent firefighting water from entering watercourses
Personal Precautions: Use respiratory protection, gloves, eye/face protection; evacuate unnecessary personnel
Environmental Precautions: Prevent further leakage or spillage if safe to do so; avoid discharge into drains, watercourses, or soil
Methods for Clean Up: Sweep up and collect without creating dust; place in clearly labelled waste container for disposal; ventilate area
Other Advice: Report large scale releases to local authorities
Precautions for Safe Handling: Avoid contact with skin, eyes, and clothing; prevent dust formation; use in well-ventilated areas; wash hands after handling
Suitable Storage Conditions: Keep container tightly sealed in a dry, cool location; avoid exposure to moisture and incompatible materials
Storage Incompatibilities: Strong oxidizers, acids, bases
Special Requirements: Use original containers; label appropriately to avoid misuse
Occupational Exposure Limits: Not established for this compound; handle using best laboratory practices
Engineering Controls: Local exhaust ventilation or process enclosure to control dust
Personal Protective Equipment:
— Respiratory protection if dust or fumes are generated
— Safety goggles to prevent eye contact
— Chemical-resistant gloves for skin protection
— Protective lab coat or apron
Hygiene Measures: No eating, drinking, or smoking in work areas; wash hands thoroughly after handling
Appearance: White to off-white crystalline powder
Odor: Mild or odorless
Odor Threshold: Not determined
pH: 4.5–6.5 (1% solution in water)
Melting Point: 200–210°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible
Vapor Density: Not relevant
Solubility: Soluble in water, dimethyl sulfoxide, methanol
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not available
Decomposition Temperature: >220°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal use and storage conditions
Possible Hazardous Reactions: May react with strong oxidizing or reducing agents
Conditions to Avoid: Excessive heat, moisture, strong acids and bases, ignition sources
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides
Acute Toxicity: Oral LD50 (rat) >2000 mg/kg (low toxicity)
Skin Corrosion/Irritation: May cause mild irritation in susceptible individuals
Serious Eye Damage/Irritation: Temporary discomfort, tearing, or redness possible
Respiratory or Skin Sensitization: No reports of sensitization under controlled use
Germ Cell Mutagenicity: No data suggesting mutagenic effects
Carcinogenicity: Not listed by IARC, ACGIH, NTP, OSHA
Reproductive Toxicity: No reproductive effects observed in animal studies at relevant doses
Specific Target Organ Toxicity (Single/Repeated Exposure): Not expected at workplace exposure levels
Other Information: Product is used therapeutically at monitored dosages; always follow risk assessment protocols
Ecotoxicity: Not expected to be hazardous to aquatic life in small quantities, but large releases may affect water quality
Persistence and Degradability: Bio-degradable through microbial action
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Moderate mobility in aqueous environments
Other Adverse Effects: Avoid uncontrolled environmental release; good laboratory practices reduce risk
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations
Product Disposal: Place unused material or waste in clearly labelled hazardous waste containers; incinerate or land-fill at permitted facility
Contaminated Packaging: Rinse containers thoroughly; dispose as for product
Precautions: Do not discharge to sewer systems or water bodies
UN Number: Not regulated as hazardous under international transport codes
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Transport Precautions: Use sturdy packaging to prevent breakage and limit exposure
Inventory Status: Listed under relevant chemical inventories (TSCA, REACH, DSL, etc.)
OSHA Hazard Communication: Not hazardous
SARA Title III (Sections 311/312): No hazard categories assigned
WHMIS Classification (Canada): Not controlled
California Proposition 65: Not listed
Other Regulation: Substance may be subject to additional national or local reporting and safety obligations
