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Product Name: Troxerutin
Chemical Name: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy)-4-chromenone
Synonyms: Vitamin P4, O-(β-Hydroxyethyl)rutoside
Molecular Formula: C33H42O19
Molecular Weight: 742.68 g/mol
Recommended Use: Pharmaceutical applications, dietary supplement
Supplier: See shipping documents or supplier address
Contact Information (Emergency): Call local poison control center or supplier emergency hotline
GHS Classification: Not classified as hazardous under GHS criteria
Physical State: Powder or crystalline solid
Color: Light yellow to off-white
Major Hazards: Dust formation possible, slight irritation to eyes, skin, or respiratory tract; otherwise low hazard potential under normal handling
Signal Word: None
Hazard Symbols: None required
Precautionary Statements: Avoid inhaling dust, contacting eyes, or prolonged skin exposure; practice standard laboratory hygiene
Substance: Troxerutin
CAS Number: 7085-55-4
EC Number: 230-391-5
Purity: ≥98% (typical specification for pharmaceutical-grade material)
Impurities: Trace levels of structurally related flavonoids (generally <1%)
Other Additives: None required for pure substance
Inhalation: Move victim to fresh air, seek medical attention if symptoms such as coughing or shortness of breath persist
Skin Contact: Wash skin thoroughly with soap and water, remove contaminated clothing if irritation or discomfort occurs
Eye Contact: Rinse eyes cautiously with clean water for several minutes; remove contact lenses if present and easy to do
Ingestion: Rinse mouth if troxerutin is swallowed, do not induce vomiting unless directed by a medical professional; call physician if large amount swallowed or if symptoms result
Symptoms to Watch For: Mild irritation to eyes, respiratory tract, or skin, particularly in case of significant exposure
Notes for Physicians: Treat based on symptoms; no known antidote required
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Specific Hazards from Fire: Combustion generates carbon oxides and other organic byproducts
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Advice: Move containers from fire area if safe to do so, use water spray to cool unopened containers, avoid breathing smoke or fumes
Personal Precautions: Prevent dust formation, wear gloves, safety glasses, laboratory coat, and approved dust mask
Environmental Precautions: Keep troxerutin out of surface waters or drains; sweep up and place in appropriate container for disposal
Cleanup Methods: Collect material using methods that minimize dust release, ventilate area, wash spill site when clean-up complete
Disposal: Dispose of spill cleanup materials in accordance with local regulations and company policy
Handling: Minimize dust generation and accumulation, use only in ventilated areas, avoid inhalation and contact with skin or eyes
Storage Conditions: Store in tightly closed containers, in a cool, dry, well-ventilated place, away from strong oxidizing agents or sources of ignition
Special Storage Requirements: Protect from direct sunlight and moisture, do not store near food or feed
Exposure Limits: No established OSHA or ACGIH exposure limits
Engineering Controls: Use exhaust ventilation or other engineering controls to keep airborne levels below recommended exposure limits
Personal Protective Equipment: Protective gloves (nitrile or latex), safety glasses with side-shields or chemical goggles, lab coat, dust mask or particulate respirator if dust potential is high
Hygiene Measures: Wash hands after handling, before breaks, and at end of work; avoid eating or drinking in work area
Appearance: Light yellow or off-white crystalline powder
Odor: Odorless
pH: Approx. 5.0 – 7.5 (1% aqueous solution)
Melting Point: Approx. 230°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water, sparingly soluble in ethanol
Density: Approx. 1.65 g/cm³
Vapor Pressure: Negligible at ambient temperature
Flash Point: Not determined
Partition Coefficient (n-octanol/water): log Kow approx. -1.7
Other Properties: Stable under normal storage and handling conditions
Reactivity: Stable in normal conditions
Chemical Stability: Stable at recommended storage conditions
Incompatible Materials: Strong acids, strong oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, low molecular weight organic compounds
Hazardous Polymerization: Not expected
Conditions to Avoid: Excess heat, moisture, direct sunlight
Acute Toxicity: Oral (rat) LD50 > 5000 mg/kg, low toxic potential
Skin Irritation: Mild transient irritation possible on prolonged exposure
Eye Irritation: Mild transient irritation
Sensitization: No data indicating skin or respiratory sensitization in humans
Chronic Toxicity: Studies in animals and humans indicate minimal or no chronic toxicity at expected exposure levels
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen
Mutagenicity: No significant genotoxic effects reported in available data
Other Health Effects: No evidence of significant health effects reported for occupational exposure in pharmaceutical handling environments
Ecotoxicity: Not expected to be acutely toxic to aquatic life
Persistence and Degradability: Readily biodegradable in sewage and soil environments
Bioaccumulative Potential: Low, due to high solubility and low partition coefficient
Mobility in Soil: Highly mobile in aqueous environments
Other Adverse Effects: No known significant environmental effects or critical hazards
Waste Disposal Methods: Dispose of material in accordance with local, regional, and national regulations for non-hazardous organic chemicals
Contaminated Packaging: Rinse and dispose of containers as non-hazardous waste, if allowed by regulations
Precautions: Prevent spillage from entering drains or waterways, incinerate or landfill using authorized facilities as per environmental guidelines
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Transport Labels: None required
Special Precautions: Avoid rough handling to prevent package breakage and dusting
Environmental Hazards: None expected
TSCA Status: Listed or exempt
REACH Status: Pre-registered or registered substance in the EU
OSHA Hazard Communication: Not hazardous
WHMIS (Canada): Not controlled
Other National Inventories: Listed in most country inventories
Labeling Requirements: Standard labeling, non-hazardous for laboratory or industrial use
Restrictions: None identified for pharmaceutical or research handling
SARA Title III, Section 313: Not subject to reporting
California Proposition 65: Not listed as causing cancer, birth defects, or other reproductive harm
